Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2071393
Xin Hong, Huan Liu
{"title":"Size-dependent amplitude and phase distribution under a high NA objective","authors":"Xin Hong, Huan Liu","doi":"10.1117/12.2071393","DOIUrl":"https://doi.org/10.1117/12.2071393","url":null,"abstract":"The interactions between light and sub-wavelength sized dielectric particles have been paid more attentions especially in biotechnology and photonics. Base on Mie scattering method, we calculate the electrical field distribution scattered by a single dielectric particle which is focused by a high numerical aperture (NA) objective. The theoretical result indicates a size dependent amplitude and phase distribution, which agrees well with the experimental measurement. This method provides a way to evaluate the particles size down to the range of less than diffraction limitation.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114691009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2074234
Jian Wang, Dijun Chen, H. Cai, R. Qu, W. Fang, Z. Fang
{"title":"High side-mode suppression ratio laser output by single sideband injection locking of semiconductor lasers","authors":"Jian Wang, Dijun Chen, H. Cai, R. Qu, W. Fang, Z. Fang","doi":"10.1117/12.2074234","DOIUrl":"https://doi.org/10.1117/12.2074234","url":null,"abstract":"High side-mode suppression ratio (SMSR) and higher optical power output of frequency converted lightwave is successfully realized by single side band injection locking of distributed feedback laser (DFB). This method is of great potential in the application of fast optical frequency sweep signal generation. Compared to that acquired from direct carrier suppressed single sideband (CS-SSB), the SMSR of the injection locked slave laser by single sideband injection locking is much higher (32.5dB to 12dB at best), and the power of the injection locked slave laser output is 11dB higher (-22dBm to -33.5dBm) than converting directly from CS-SSB. The variation of SMSR and locking bandwidth of the slave laser as optical injection ratio changes is also researched.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"170 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123189580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2070929
Peng Liu, Si Di, Jian Jin, Liping Bai
{"title":"Enhancement display of veins distribution based on binocular vision and image fusion technology","authors":"Peng Liu, Si Di, Jian Jin, Liping Bai","doi":"10.1117/12.2070929","DOIUrl":"https://doi.org/10.1117/12.2070929","url":null,"abstract":"The capture and display of veins distribution is an important issue for some applications, such as medical diagnosis and identification. Therefore, it has become a popular topic in the field of biomedical imaging. Usually, people capture the veins distribution by infrared imaging, but the display result is similar with that of a gray picture and the color and details of skin cannot be remained. To some degree, it is unreal for doctors. In this paper, we develop a binocular vision system to carry out the enhancement display of veins under the condition of keeping actual skin color. The binocular system is consisted of two adjacent cameras. A visible band filter and an infrared band filter are placed in front of the two lenses, respectively. Therefore, the pictures of visible band and infrared band can be captured simultaneously. After that, a new fusion process is applied to the two pictures, which related to histogram mapping, principal component analysis (PCA) and modified bilateral filter fusion. The final results show that both the veins distribution and the actual skin color of the back of the hand can be clearly displayed. Besides, correlation coefficient, average gradient and average distortion are selected as the parameters to evaluate the image quality. By comparing the parameters, it is evident that our novel fusion method is prior to some popular fusion methods such as Gauss filter fusion, Intensity-hue-saturation (HIS) fusion and bilateral filter fusion.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115040060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2071845
Weiwei Wang, Xiao-tong Li, Z. Cen, Luwei Zhang
{"title":"Analysis of nonlinear self-focusing phenomenon in high-power laser system based on ray-tracing","authors":"Weiwei Wang, Xiao-tong Li, Z. Cen, Luwei Zhang","doi":"10.1117/12.2071845","DOIUrl":"https://doi.org/10.1117/12.2071845","url":null,"abstract":"In high power laser systems, nonlinear effect, one of the key factors of beam wavefront aberration and even irreversible damage to system, has always been one of the top considerations of researchers for decades. A hybrid ray-tracing method for both linear media and nonlinear media based on geometric optics is presented in this paper and realized by programming. In a simple optic system with KDP crystal, an obvious decline of beam quality is observed in high laser power density conditions and a method taking component intervals as compensation of beam quality is proved feasible. Considering the complexity of traditional modeling method based on surfaces, a modeling method based on components is established. Hopefully, the conclusions and flaws of this paper can shed light on relevant work and further research.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133866010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of laser fluence in protein synthesis of cultured DRG neurons following low-level laser irradiation","authors":"Liqin Zheng, Caimin Qiu, Yu-hua Wang, Yixiu Zeng, Hongqin Yang, Yanding Zhang, S. Xie","doi":"10.1117/12.2071447","DOIUrl":"https://doi.org/10.1117/12.2071447","url":null,"abstract":"Low-level lasers have been used to relieve pain in clinical for many years. But the mechanism is not fully clear. In animal models, nitric oxide (NO) has been reported involving in the transmission and modulation of nociceptive signals. So the objective of this study was to establish whether low-level laser with different fluence could stimulate the production of nitric oxide synthese (NOS), which produces NO in cultured primary dorsal root ganglion neurons (DRG neurons). The primary DRG neurons were isolated from healthy Sprague Dawley rats (8-12 weeks of age) and spread on 35 mm culture dishes specially used for confocal microscopy. 24 hours after spreading, cells were irradiated with 658 nm laser for two consecutive days at the energy density of 20, 40, 60 and 80 mJ·cm-2 respectively. Control groups were not exposed to the laser, but were kept under the same conditions as the irradiated ones. The synthesis of NOS after laser irradiation was detected by immunofluorescence assay, and the changes of NOS were evaluated using confocal microscopy and Image J software. The results showed that all the laser fluence could promote the production of NOS in DRG neurons, especially the 60 mJ·cm-2 . These results demonstrated that low-level laser irradiation could modify protein synthesis in a dose- or fluence- dependent manner, and indicated that low-level laser irradiation might achieve the analgesic effect through modulation of NO production.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133288197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2071011
Xiao-dong Wang, Q. Zhu, Jing-qin Su, N. Xie, Dongbin Jiang, K. Zhou, Xiao-jun Huang, X. Zeng, Yi Guo, Li Sun, Qing Li
{"title":"Development of a sub-petawatt ultrashort laser facility","authors":"Xiao-dong Wang, Q. Zhu, Jing-qin Su, N. Xie, Dongbin Jiang, K. Zhou, Xiao-jun Huang, X. Zeng, Yi Guo, Li Sun, Qing Li","doi":"10.1117/12.2071011","DOIUrl":"https://doi.org/10.1117/12.2071011","url":null,"abstract":"The paper presents the development of a sub-petawatt ultrashort laser facility, i.e. the upgraded super intense laser for experiment on the extremes (SILEX-I). The facility is a multi-stage Ti:sapphire chirped pulse amplification (CPA) laser system. Cross-polarized wave generation was used to improve the temporal contrast. An adaptive optical system was utilized to correct wavefront aberrations and to improve focusability before each shot. After upgrading, the maximum energy is 20.1 J, the recompressed pulse width is 26.8 fs and the peak power is up to 750 TW. The temporal contrast is around 109. The on-target focal spot size (full width at half maximum (FWHM)) is Φ6.5 μm and the focused intensity is greater than 4x1020 W/cm2.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133503421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2070398
Liang Xue, Nan Sun, Keding Yan, Fei Liu, Shouyu Wang
{"title":"High-speed quantitative interferometric microscopy based phase imaging cytometer","authors":"Liang Xue, Nan Sun, Keding Yan, Fei Liu, Shouyu Wang","doi":"10.1117/12.2070398","DOIUrl":"https://doi.org/10.1117/12.2070398","url":null,"abstract":"The paper proposed a simple large scale bio-sample phase detecting equipment called gravity driven phase detecting cytometer, which is based on quantitative interferometric microscopy to realize flowing red blood cells phase distribution detection. The method has advantages on high throughput phase detecting and statistical analysis with high detecting speed and in real-time. The statistical characteristics of red blood cells are useful for biological analysis and disease detection. We believe this method is shedding more light on quantitatively measurement of the phase distribution of bio-samples.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125907586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2071307
Feng-juan Zhang, Xiaoming Hu, Qishen Zhang
{"title":"The evaluation and planning of light dose in photodynamic therapy for port wine stains","authors":"Feng-juan Zhang, Xiaoming Hu, Qishen Zhang","doi":"10.1117/12.2071307","DOIUrl":"https://doi.org/10.1117/12.2071307","url":null,"abstract":"Photodynamic therapy (PDT) is one of the best available treatment for dermatology, especially for port wine stains (PWS), in which the efficacy is associated with the light dose, the photosensitizer concentration, the oxygen concentration and so on. Accurate control of the light dose will help doctors develop more effective treatment protocols, and reduce the treatment cost. Considering the characters of PWS, a binocular vision system composed of a camera, a digital projector and a computing unit is designed. An accurate 3D modeling of patients was achieved using a gray coding structured light, and then the lesions were segmented based on HSV space. Subsequently, each 3D point is fit on the surface by a nearest neighbor algorithm and the surface normal can be obtained. Three dimensional localization of lesion provide digital objective basis for automatic control of light device. The irradiance on the surface at a given angle can be assessed, and the optimum angle for the treatment can be solved and optimized by the doctor to improve irradiation areas.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126165261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2074476
P. Zhu, Xinglong Xie, Jianqiang Zhu, Haidong Zhu, Qingwei Yang, Jun Kang, Ailin Guo, Qi Gao
{"title":"Analysis of temporal contrast degradation due to wave front deviation in large aperture ultra-short pulse focusing system","authors":"P. Zhu, Xinglong Xie, Jianqiang Zhu, Haidong Zhu, Qingwei Yang, Jun Kang, Ailin Guo, Qi Gao","doi":"10.1117/12.2074476","DOIUrl":"https://doi.org/10.1117/12.2074476","url":null,"abstract":"In extremely intense laser system used for plasma physics experiments, temporal contrast is an important property of the ultra-short pulse. In this paper, we theoretically study the temporal contrast degradation due to wave front deviation in large aperture ultra-short pulse focusing system. Two-step focusing fast Fourier transform (FFT) algorithm with the coordinate transform based on Fresnel approximation in space domain and Fourier integral transform method in time domain were used to simulate the focusing process spatially and temporally, in which the spatial distribution of ultra-short pulse temporal contrast characteristics at the focal spot is related to the wave front in large aperture off-axis parabolic mirror focusing optical system. Firstly, temporal contrast degradation due to wave front noise with higher spatial frequency is analyzed and appropriate evaluation parameter for large aperture ultra-short pulse focusing system is put forward from the perspective of temporal contrast. Secondly, the influence of wave front distortion with lower spatial frequency on temporal contrast is revealed comparing different degradation characteristics of various aberrations. At last, a method by controlling and optimizing the wave front to prevent temporal contrast degradation in large aperture ultra-short laser system is proposed, which is of great significance for high temporal contrast petawatt laser facilities.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130420105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photonics AsiaPub Date : 2014-11-18DOI: 10.1117/12.2071537
Shi-yu Zhang, Xiaoming Hu, Ya Zhou
{"title":"The simulation of light distribution in photodynamic therapy for port wine stains","authors":"Shi-yu Zhang, Xiaoming Hu, Ya Zhou","doi":"10.1117/12.2071537","DOIUrl":"https://doi.org/10.1117/12.2071537","url":null,"abstract":"Photodynamic Therapy is regarded as the best treatment for port wine stains, which has the main adverse effect of various degrees of pain (mild to moderate) during the illumination. Though the cooling and cold water have been used to reduce such pain, there is still no scientific evidence for these relief. In this paper, a realistic skin model is built to simulate the distribution of light under treatment, which helps control the light dose and temperature, and improve the clinical results. Comparing with the general parallel skin model, a curving stratum basale layer is used in this paper, and various blood vessel configurations such as single and multiple vessels with horizontally and vertically oriented, curve vessels, various vessel diameter and various radius of curvature of stratum basale layer are simulated. The results shows a more realistic modeling for the thermal damage and help to relief the pain in the treatment.","PeriodicalId":164339,"journal":{"name":"Photonics Asia","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127145729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}