Journal of Intensive Care Medicine最新文献

{"title":"Impact of Metabolically Healthy and Unhealthy Obesity on Outcomes of Sepsis Complicated by Septic Shock in Elderly Patients.","authors":"Giorgi Chilingarashvili, Diksha Sanjana Pasnoor, Shreya Bajjuri, Ritika Parekh, Nirmala Manjappachar, Jyotsna Gummadi, Athmananda Nanjundappa, Rupak Desai","doi":"10.1177/08850666251372543","DOIUrl":"https://doi.org/10.1177/08850666251372543","url":null,"abstract":"<p><strong>Purpose: </strong>Obesity is a risk factor for sepsis complications in older adults. We assessed the impact of metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO) on outcomes in septic shock.</p><p><strong>Methods: </strong>We conducted a retrospective analysis using the National Inpatient Sample (2016-2020) to identify a cohort of 1,737,075 patients aged 65 years and older who were hospitalized with septic shock, as defined by ICD-10 diagnosis codes. Obese patients without hypertension, diabetes, or hyperlipidemia were classified as MHO; those with ≥1 risk factor as MUHO. Baseline demographics and hospital characteristics were compared using χ² and Mann-Whitney U tests. Multivariable logistic regression adjusted for age, sex, race, comorbidity index, and hospital factors estimated odds ratios (ORs) for respiratory failure, mechanical ventilation, in-hospital mortality, and cardiac arrest. Secondary endpoints included length of stay (LOS) and hospitalization cost.</p><p><strong>Results: </strong>Among 268 050 obese patients, 23 915 (1.4%) were classified as MHO and 244 135 (14.1%) as MUHO. Both phenotypes were more prevalent in females and least common among Asian patients. MHO prevalence was highest among Native Americans, while MUHO was most common among Hispanics in 2020. From 2016 to 2019, the prevalence of both phenotypes remained stable, with modest increases observed during the 2020 sepsis surge. Respiratory failure occurred most frequently in the MHO group (∼70%), followed by MUHO (∼65%) and non-obese patients (∼60%). After adjusting for confounders, both MHO and MUHO groups had higher odds of respiratory failure and mechanical ventilation compared to non-obese patients. In-hospital mortality increased across all groups in 2020; however, MUHO patients had lower adjusted mortality risk. Cardiac arrest rates remained unchanged, while length of stay and hospitalization costs were highest among MHO patients.</p><p><strong>Conclusions: </strong>MHO and MUHO both confer higher respiratory failure and ventilation risk; lower mortality in MUHO warrants further study.Clinical ImplicationsPhenotypic obesity classification may improve sepsis risk stratification and inform metabolic-specific management.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251372543"},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Based Assessment of Rectus Femoris Muscle Wasting as a Predictor of 28-Day Mortality in Septic Shock: A Prospective Study.","authors":"Nguyen Thi Huyen Trang, Le Thi Viet Hoa, Pham Dang Hai","doi":"10.1177/08850666251370636","DOIUrl":"https://doi.org/10.1177/08850666251370636","url":null,"abstract":"<p><strong>Background: </strong>Bedside ultrasound is increasingly utilized to assess muscle mass in critically ill patients, providing a noninvasive and real-time tool for early risk stratification. Muscle wasting is known to be associated with adverse outcomes in septic shock, but its prognostic value using ultrasound in this population remains underexplored. This study aimed to investigate the association between changes in rectus femoris cross-sectional area (CSA), assessed by bedside ultrasound, and 28-day mortality in patients with septic shock.</p><p><strong>Methods: </strong>This prospective observational study enrolled adult patients (≥18 years) with septic shock admitted to the intensive care unit (ICU), diagnosed according to Sepsis-3 criteria. Ultrasound assessments of rectus femoris CSA were performed at baseline (day 0), day 4, and day 7 using a linear transducer. The primary outcome was 28-day mortality. Percentage change in CSA was calculated, and its association with mortality was evaluated using multivariable logistic regression and receiver operating characteristic (ROC) analysis.</p><p><strong>Results: </strong>A total of 116 patients were included. The 28-day mortality rate was 20.7%. Rectus femoris CSA decreased significantly over time, with a median reduction of -0.35 cm² (IQR: -0.62 to -0.21) by day 7. The percentage decrease in CSA was significantly greater in non-survivors at both day 4 (-10.0% vs -8.5%, <i>P</i> = .041) and day 7 (-15.4% vs -13.5%, <i>P</i> = .044). In multivariable analysis, percentage CSA loss at day 7 was independently associated with 28-day mortality (OR 0.94, 95% CI 0.88-0.99, <i>P</i> = .036). ROC analysis yielded an area under the curve (AUC) of 0.65 (95% CI 0.52-0.78) for %CSA reduction at day 7, with a -15.28% cut-off showing 66.7% sensitivity and 61.9% specificity.</p><p><strong>Conclusions: </strong>Serial ultrasound assessment of rectus femoris CSA is a feasible and reproducible method for monitoring muscle wasting in septic shock. While the predictive performance was modest, serial ultrasound measurements may serve as a valuable adjunct in early mortality risk stratification in critically ill patients.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251370636"},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic and Therapeutic Impact of Critical Care Echocardiography in Patients Admitted in the Intensive Care Unit for Circulatory Or Respiratory Failure Report from an Expert Center.","authors":"Victor Penaud, Cyril Charron, Eve Garrigues, Pierre-Alexandre Haruel, Edouard Jullien, Romain Jouffroy, Sylvie Meireles, Matthieu Petit, Amélie Prigent, Victor Beaucote, Guillaume Salama, Adrien Joseph, Antoine Vieillard-Baron","doi":"10.1177/08850666251356987","DOIUrl":"https://doi.org/10.1177/08850666251356987","url":null,"abstract":"<p><p>PurposeCritical Care Echocardiography (CCE) is now a major tool in assessments of ICU patients. We aimed to evaluate its clinical impact in patients admitted to the intensive care unit for acute respiratory failure (ARF) or shock.MethodsWe conducted a single-center retrospective observational study of all patients admitted between January 1th and December 31st 2019 for ARF or shock, who received CCE in the first 12 h of admission. The primary outcome was the therapeutic impact associated with CCE. Secondary outcomes included differences in therapeutic impact between ARF and shock patients, and between trans-thoracic (TTE) and trans-esophageal (TEE) CCE.Results486 patients were potentially eligible, 109 were excluded because CCE was performed after 12 h or because of missing CCE report. 329 patients were analyzed, 31% with shock, 44% with ARF, 25% with both. TTE was performed in 71%, TEE in 29%. All TEE patients were invasively mechanically ventilated and 65% of invasively ventilated patients underwent TEE. No TEE-related complications were observed. CCE was followed with 363 therapeutic interventions in 231 (70%) patients within 2 h. The most common involved hemodynamic optimization in 193 patients (59%), including fluid expansion (129 patients, 39%), vasopressor initiation (39 patients, 12%), vasopressor dose adjustment (79 patients, 24%), inotrope initiation (15 patients, 4.5%), inotrope dose adjustment (5 patients), and others like cardioversion (4 patients) and veno-arterial ECMO implantation (3 patients). TEE patients were more likely to receive therapeutic changes, notably significantly more fluids (53% vs 34% p = 0.0014) and had more frequent vasopressor dose adjustments (64% vs 24% p < 0.001).ConclusionsCCE was followed with therapeutic interventions in nearly 70% of patients admitted for ARF or shock, emphasizing its diagnostic value. Hemodynamic optimization was the primary intervention. We have not found any complications or adverse events of TEE in our cohort.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251356987"},"PeriodicalIF":2.1,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midline Catheters as an Alternative for Central Venous Catheters in Venous Pressure Monitoring: A Single Center Experience.","authors":"Brendan Sweeney, Justin Kim, Ariana Adnani, Huma Saleem, Seda Akben, Yin Rong Alvina Teo, Eduard Shaykhinurov, Maria Wu, Rishika Bheem, Samita Islam, Danielle Davison, Katrina Hawkins, Daniel King, Sasa Ivanovic, David P Yamane","doi":"10.1177/08850666251368867","DOIUrl":"https://doi.org/10.1177/08850666251368867","url":null,"abstract":"<p><p>PurposeMidline catheters (ML) are long peripheral intravenous catheters placed in an upper extremity above the antecubital fossa via the basilic, cephalic, or brachial veins. These provide safe and comfortable long-term vascular access for critically ill patients. Central venous pressures (CVP) are obtained from central venous catheters (CVC) and are often used as resuscitation parameters. Given the proximity of ML to the axillary vein, we investigated if midline venous pressure (MVP) is comparable to CVP.MethodsThis is an observational study conducted in adult critical care patients at a tertiary academic center. Inclusion criteria were patients with a CVC in the subclavian or internal jugular veins and a ML in place as part of standard ICU care. Pressure measurements were recorded from both catheters every 15 min over a 60-min period. Demographic, clinical, and physiological data points were collected. Continuous variables were analyzed using the t-test. Pearson correlation was used to evaluate the relationship between the paired variables.ResultsWe enrolled 50 patients with 5 pressure measurements taken per patient (n = 250). The mean MVP and CVP were 10.6 ± 6.4 mm Hg and 9.1 ± 6.3 mm Hg, respectively (<i>P</i> < .001). In Bland Altman analysis, the mean bias was -1.48 ± 3.99 mm Hg with limits of agreement of -9.3 mm Hg to 6.3 mm Hg. The Pearson correlation coefficient was 0.8 (<i>P</i> < .001).ConclusionsOur study investigated MVP as a correlate of CVP. Our results show a mean bias of -1.48 ± 3.99 mm Hg and a strong positive Pearson correlation coefficient of 0.8 between the MVP and the CVP. The large limits of agreement indicate MVP and CVP are not interchangeable. Despite this, clinically significant pressure values from CVCs and MLs trend similarly.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251368867"},"PeriodicalIF":2.1,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"State-of-the-art Neurointervention for Extended Window and Large Ischemic Core.","authors":"Kiwon Lee, Danielle Mahon","doi":"10.1177/08850666251346147","DOIUrl":"https://doi.org/10.1177/08850666251346147","url":null,"abstract":"<p><p>The implementation of endovascular therapy as a treatment for acute ischemic stroke has developed greatly in recent years. The primary trials demonstrated negative to mixed results, and it wasn't until the MR CLEAN trial that thrombectomy was established as a beneficial treatment. Since then, further studies have continued to provide additional data allowing for expansion of patient eligibility to receive such therapy. This manuscipt highlights the development and progression of the utilization of endovascular treatment in acute ischemic stroke.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251346147"},"PeriodicalIF":2.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-linear Association Between Lactate Levels and ICU Mortality in Septic Patients: A Multi-Center Study of 13,888 Cases.","authors":"Lei Zhao, Rong Zhang","doi":"10.1177/08850666251366228","DOIUrl":"10.1177/08850666251366228","url":null,"abstract":"<p><p>BackgroundBlood lactate is a crucial prognostic indicator in sepsis, but its non-linear relationship with mortality remains unclear. This study aimed to investigate the complex association between lactate levels and ICU mortality in septic patients.MethodsIn this multi-center retrospective study of 13,888 septic patients from the eICU database, we analyzed the association between admission lactate levels and ICU mortality using multivariate models and threshold effect analysis. Models were adjusted for demographics, comorbidities, laboratory parameters, medications, mechanical ventilation status, and APACHE IV scores.ResultsA total of 13,888 septic patients were recruited, including 1688 (12.2%) with ICU mortality. Admission lactate level was positively correlated with ICU mortality. When adjusting for potential confounders, the ICU mortality risk in patients in the highest lactate quartile (>5.2 mmol/L) increased by 133% relative to those in the lowest quartile (<2.0 mmol/L) (OR 2.33, 95% CI 1.91-2.83, P < 0.001). No significant interactions were observed in subgroups based on age, sex, BMI, APACHE IV score, acute myocardial infarction, renal replacement therapy, or vasopressor use (all P-interaction >0.05)，however, Significant interactions were observed in subgroups based on acute respiratory failure (P-interaction <0.001) and mechanical ventilation (P-interaction = 0.004).ConclusionLactate demonstrates a non-linear relationship with ICU mortality in septic patients, with 6.09 mmol/L as a critical threshold. This finding provides evidence for risk stratification and treatment decisions in sepsis management.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251366228"},"PeriodicalIF":2.1,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographic Variations of Intensive Care Unit Admissions with Substance-Related Diagnoses in the United States.","authors":"Kelsey Hills-Dunlap, Max McGrath, Ryan Peterson, Ariyani Challapalli, P Michael Ho, Tyree H Kiser, R William Vandivier, Sarah E Jolley, Marc Moss, Ellen L Burnham","doi":"10.1177/08850666251372491","DOIUrl":"10.1177/08850666251372491","url":null,"abstract":"<p><p>BackgroundSubstance use is an important contributor to morbidity, mortality, and healthcare utilization in the United States. While prior research has explored regional differences in substance use and related hospitalizations, the geographic variation in substance-related ICU admissions remains underexplored. We sought to compare the prevalence of ICU admissions involving substance use across geographic divisions and between urban and rural ICUs in the United States.MethodsUsing the national PINC AI Healthcare Database, we performed a retrospective observational study of adult ICU admissions between January 1, 2016 and December 31, 2019 with a substance-related ICD-10 diagnosis. We calculated the proportion of all ICU admissions with diagnoses related to any substance, and separately for alcohol, opioids, and stimulants and compared these across U.S. Census divisions and between urban and rural ICUs.ResultsOut of 4,740,799 ICU admissions, 760,153 (16.0%) included at least one substance-related diagnosis. The highest burden of substance-related diagnoses was observed in the New England, Pacific, and Mountain divisions, where alcohol and opioid-related ICU admissions were most prevalent. Stimulant-related ICU admissions were disproportionately higher in the Pacific division. Urban ICUs generally reported a higher proportion of substance-related admissions compared to rural ICUs, with certain regional exceptions.ConclusionThere are substantial geographic and urban-rural differences in substance-related ICU admissions across the United States. Our findings suggest a need for region-specific strategies to address distinct substance use patterns and reduce the burden on critical care resources.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251372491"},"PeriodicalIF":2.1,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Detection of Sepsis Using Artificial Intelligence in Intensive Care Units: A Systematic Review and Meta-Analysis.","authors":"Xiaomeng Ji, Huasong Huo, Lihua Dong","doi":"10.1177/08850666251372499","DOIUrl":"https://doi.org/10.1177/08850666251372499","url":null,"abstract":"<p><p>PurposeThis meta-analysis aimed to assess the diagnostic performance of artificial intelligence for detecting sepsis in intensive care unit.MethodsA thorough literature search was performed using PubMed, Embase, and Web of Science to locate relevant studies published through November 2024. The selected studies specifically examined the diagnostic accuracy of artificial intelligence in identifying septicemia. To estimate pooled sensitivity and specificity values, a bivariate random-effects model was employed, with results reported alongside 95% confidence intervals. Heterogeneity across studies was evaluated using the I² statistic.ResultsOf the 1495 studies initially identified, 16 studies encompassing a total of 159,947 patients, met the inclusion criteria for this meta-analysis. For the internal validation set, the pooled results for sepsis detection showed a sensitivity of 0.76 (95% CI: 0.71-0.80), a specificity was of 0.85 (95% CI: 0.81-0.89), and an area under the curve (AUC) of 0.87 (95% CI: 0.84-0.90). In comparison, the external validation set yielded a sensitivity of 0.78 (95% CI: 0.65-0.87), a specificity of 0.82 (95% CI: 0.76-0.86), and an AUC of 0.87 (95% CI: 0.83-0.89). Deeks' funnel plot and Egger's test indicated no significant publication bias in both the internal and external validation sets(<i>P</i> = .63,.89).ConclusionsThe findings of this meta-analysis indicate that artificial intelligence demonstrates a high diagnostic performance in identifying sepsis and septic shock. However, substantial heterogeneity across studies may impact the robustness of this evidence. Further research using external validation datasets is required to confirm these results and evaluate their applicability in clinical settings.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251372499"},"PeriodicalIF":2.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Early Versus Delayed Initiation of Vasopressin in Post-Cardiothoracic Surgery Vasoplegic Shock and the Effect on Post-Operative Atrial Fibrillation.","authors":"Kinsey Smith, Roberto Montealegre, Britton Blough, Vivek Kataria","doi":"10.1177/08850666251364773","DOIUrl":"https://doi.org/10.1177/08850666251364773","url":null,"abstract":"<p><p>Post-operative complications of cardiothoracic surgery include vasoplegic shock and post-operative atrial fibrillation (POAF). Use of catecholamines for vasoplegic shock may enhance the risk of POAF; thus, use of non-catecholamine vasopressors is reasonable. This retrospective, single-center cohort study compared early to delayed initiation of vasopressin in vasoplegic shock and assessed the association with POAF. Patients were included if they were ≥ 18 years of age, underwent cardiothoracic surgery, and were diagnosed with vasoplegic shock requiring norepinephrine and vasopressin post-operatively. Early vasopressin use was defined as vasopressin initiated within six hours of ICU admission and delayed vasopressin use was defined as vasopressin initiated greater than six hours and up to 24 hafter ICU admission. In total, 126 patients were included. Patients were primarily male (83.3%) and Caucasian (80.1%). Most patients received coronary artery bypass grafting (77.8%). Post-operative hemodynamics were similar between groups, although patients in the early vasopressin group were more likely to receive earlier initiation of norepinephrine (17 vs 62 min, <i>P</i> < .001). Post-operative atrial fibrillation occurred in 21.8% of patients in the early vasopressin group compared to 28% of patients in the late vasopressin group during ICU admission (<i>P</i> = .508), with most patients on vasopressors at time of POAF onset (72.4%). Observations in patients who received early vasopressin were shorter duration of vasoplegic shock (39 vs 60 h, <i>P</i> < .001), shorter ICU length of stay (2.2 vs 3 days, <i>P</i> = .009) and shorter hospital length of stay (7.1 vs 9.8 days, <i>P</i> = .005). Multivariate logistic regression with variables including intraoperative vasopressin use and the POAF score did not impact the primary outcome. Early initiation of vasopressin was not significantly associated with a decreased rate of POAF in the management of vasoplegic shock after cardiothoracic surgery. Further investigation into early vasopressin use in this patient population is warranted.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"8850666251364773"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Part 1: Current Concepts in Radiologic Imaging and Intervention in Acute Cholecystitis.","authors":"Easton Neitzel, Julia Laskus, Peter R Mueller, Avinash Kambadakone, Shravya Srinivas-Rao, Eric vanSonnenberg","doi":"10.1177/08850666241259421","DOIUrl":"10.1177/08850666241259421","url":null,"abstract":"<p><p>Acute calculous cholecystitis and acute acalculous cholecystitis are encountered commonly among critically ill, often elderly, patients. Multidisciplinary management of these conditions is essential, with intensivists, surgeons, diagnostic radiologists, interventional radiologists, infectious disease physicians, gastroenterologists, and endoscopists able to contribute to patient care. In this article intended predominantly for intensivists, we will review the imaging findings and radiologic treatment of critically ill patients with acute calculous cholecystitis and acute acalculous cholecystitis.</p>","PeriodicalId":16307,"journal":{"name":"Journal of Intensive Care Medicine","volume":" ","pages":"919-928"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}