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Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases最新文献

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Utility of Joint Population Exposure-Response Modeling Approach to Assess Multiple Continuous and Categorical Endpoints in Immunology Drug Development 联合人群暴露-反应建模方法在免疫药物开发中评估多个连续和分类终点的效用
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH6
Chuanpu Hu, Honghui Zhou
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引用次数: 0
Model-Based Meta-Analysis Use in the Development of Therapeutic Proteins 基于模型的荟萃分析在治疗性蛋白质开发中的应用
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH5
T. Taylor, B. Frame, Angela D. Taylor
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引用次数: 0
Mechanism and Physiologically Based PK/PD Model in Assisting Translation from Preclinical to Clinical: Understanding PK/PD of Therapeutic Proteins at Site-of-Action 机制和基于生理学的PK/PD模型协助临床前到临床的转化:了解治疗蛋白在作用位点的PK/PD
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH3
Xi Chen, Weirong Wang
{"title":"Mechanism and Physiologically Based PK/PD Model in Assisting Translation from Preclinical to Clinical: Understanding PK/PD of Therapeutic Proteins at Site-of-Action","authors":"Xi Chen, Weirong Wang","doi":"10.1002/9781119289234.CH3","DOIUrl":"https://doi.org/10.1002/9781119289234.CH3","url":null,"abstract":"","PeriodicalId":162868,"journal":{"name":"Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124644814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative Pharmacology Assessment Strategy Therapeutic Proteins in Pediatric Subjects - Challenges and Opportunities 定量药理学评估策略治疗性蛋白在儿科受试者-挑战和机遇
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH14
J. Momper, A. Mulberg, N. Mehrotra, D. Turner, W. Faubion, L. Conklin, K. Azer, M. Dubinsky
{"title":"Quantitative Pharmacology Assessment Strategy Therapeutic Proteins in Pediatric Subjects - Challenges and Opportunities","authors":"J. Momper, A. Mulberg, N. Mehrotra, D. Turner, W. Faubion, L. Conklin, K. Azer, M. Dubinsky","doi":"10.1002/9781119289234.CH14","DOIUrl":"https://doi.org/10.1002/9781119289234.CH14","url":null,"abstract":"","PeriodicalId":162868,"journal":{"name":"Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128640680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Biomarkers in Treatment Algorithms for Ulcerative Colitis (UC) 生物标志物在溃疡性结肠炎治疗算法中的作用
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH2
R. Khanna, B. Feagan
{"title":"The Role of Biomarkers in Treatment Algorithms for Ulcerative Colitis (UC)","authors":"R. Khanna, B. Feagan","doi":"10.1002/9781119289234.CH2","DOIUrl":"https://doi.org/10.1002/9781119289234.CH2","url":null,"abstract":"","PeriodicalId":162868,"journal":{"name":"Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130524435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of Minimal Anticipated Biological Effect Level (MABEL) in Human Starting Dose Selection for Immunomodulatory Protein Therapeutics - Principles and Case Studies 最小预期生物效应水平(MABEL)在人体免疫调节蛋白治疗起始剂量选择中的应用-原理和案例研究
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH4
Haiqing Wang, Zheng Yang, Rong Shi
{"title":"Application of Minimal Anticipated Biological Effect Level (MABEL) in Human Starting Dose Selection for Immunomodulatory Protein Therapeutics - Principles and Case Studies","authors":"Haiqing Wang, Zheng Yang, Rong Shi","doi":"10.1002/9781119289234.CH4","DOIUrl":"https://doi.org/10.1002/9781119289234.CH4","url":null,"abstract":"","PeriodicalId":162868,"journal":{"name":"Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115961550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Index 指数
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.index
{"title":"Index","authors":"","doi":"10.1002/9781119289234.index","DOIUrl":"https://doi.org/10.1002/9781119289234.index","url":null,"abstract":"","PeriodicalId":162868,"journal":{"name":"Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132225299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeling Approaches to Characterize Target-Mediated Pharmacokinetics and Pharmacodynamics for Therapeutic Proteins 表征靶标介导药代动力学和治疗蛋白药效学的建模方法
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH7
L. Gibiansky, E. Gibiansky
{"title":"Modeling Approaches to Characterize Target-Mediated Pharmacokinetics and Pharmacodynamics for Therapeutic Proteins","authors":"L. Gibiansky, E. Gibiansky","doi":"10.1002/9781119289234.CH7","DOIUrl":"https://doi.org/10.1002/9781119289234.CH7","url":null,"abstract":"","PeriodicalId":162868,"journal":{"name":"Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126807802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pharmacokinetics-Based Dosing Strategies for Therapeutic Proteins in Inflammatory Bowel Disease 基于药代动力学的炎症性肠病治疗蛋白给药策略
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases Pub Date : 2019-02-15 DOI: 10.1002/9781119289234.CH12
D. Mould, R. Upton, J. Wojciechowski
{"title":"Pharmacokinetics-Based Dosing Strategies for Therapeutic Proteins in Inflammatory Bowel Disease","authors":"D. Mould, R. Upton, J. Wojciechowski","doi":"10.1002/9781119289234.CH12","DOIUrl":"https://doi.org/10.1002/9781119289234.CH12","url":null,"abstract":"","PeriodicalId":162868,"journal":{"name":"Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121497176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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