M. Gürbüz, Hamdi Cakli, M. Dinçer, Durmuş Ediz, Emine Dündar, Erkan Özüdoğru
{"title":"T2N0M0 supraglottik karsinomda, sadece platinum indüksiyon kemoterapisi sonrası 54 aylık ilginç sürvi","authors":"M. Gürbüz, Hamdi Cakli, M. Dinçer, Durmuş Ediz, Emine Dündar, Erkan Özüdoğru","doi":"10.2399/JMU.2012003008","DOIUrl":"https://doi.org/10.2399/JMU.2012003008","url":null,"abstract":"Erken donem skuamoz hucreli supraglottik larenks karsinomlu hastalarin geleneksel tedavi sekli cerrahi ve/veya radyoterapidir. Literaturde larenksin erken donem kanseri olan hastalarda induksiyon veya kuratif amacla yapilan kemoterapinin basarisi ile ilgili farkli gorusler vardir. Bu calismada T2N0M0 supraglottik karsinom nedeniyle onerilen cerrahi tedaviyi kabul etmeyen ve radyoterapi oncesi iki kur sisplatin-5-FU induksiyon kemoterapisi uygulanan; ancak onerilen radyoterapiyi gormeyerek 54 ay takip disi kalan ve sonrasinda lokal nuks ve bolgesel metastaz ile basvuran bir olgu sunulmustur. Erken donem larenks karsinomlu olgularda induksiyon kemoterapisinin etkisi tartismalidir. Ancak parsiyel larenjektomiyi reddeden olgularda tedavi oncesi hasta ve ailesine verilen danismanlik da radyoterapinin olasi basarisini tahmin etmek acisindan onemlidir.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122723710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murat Kar, Imran San, Baki Korkmaz, Abdullah Ozgonul, Ismail Iynen
{"title":"Farklı belirtilerle başvuran larengofarengeal reflü olgularında 24 saatlik pH monitörizasyon sonuçları","authors":"Murat Kar, Imran San, Baki Korkmaz, Abdullah Ozgonul, Ismail Iynen","doi":"10.2399/JMU.2012003004","DOIUrl":"https://doi.org/10.2399/JMU.2012003004","url":null,"abstract":"Amac: Gastroozofageal reflunun atipik klinik sekillerinden biri olan larengofarengeal reflunun (LFR) kulak burun bogaz hastaliklari pratiginde pek cok belirtiden sorumlu oldugu dusunulmektedir. Calismamizda farkli belirtiler gosteren gruplarda LFR sikligini 24 saatlik cift kanalli pH metre monitorizasyonu ile gostermeyi amacladik. Yontem: Bu calisma, Temmuz 2007Temmuz 2008 arasinda cesitli kulak burun bogaz ve bas boyun semptomlari ile basvuran olgular uzerinde yapildi. Semptom ve bulgularina gore olgular 5 farkli grup (gastrointestinal, bronsial, larengeal, farengeal, rinolojik) ve herhangi bir yakinmasi olmayan bireylerden bir kontrol grubu olusturuldu. Tum olgulara 24 saatlik cift kanalli pH monitorizasyonu yapildi. Proksimal kanalda bir ve daha fazla pH degerinin 4.0'in altina dusmesi LFR pozitif olarak kabul edildi. Bulgular: Olcum sonuclarina gore LFR, gastrointestinal semptom grubunda %94 (18/19), bronsial semptom grubunda %96 (24/25), larengeal semptom grubunda %83 (26/31), farengeal semptom %93 (27/29), rinolojik semptom grubunda %90 (19/21), kontrol grubunda ise %10 (2/20) sikliginda tespit edilmistir. Semptomlara gore degerlendirildiginde larengofarengeal reflu en sik bronsial grupta saptanirken, en dusuk insidans larengeal grupta gozlenmistir. Sonuc: Larengofarengeal reflu, klinikte oldukca farkli kulak burun bogaz semptomlariyla karsimiza cikabilmektedir. Larengofarengeal refluden suphelenilen olgularda kesin tani icin 24 saatlik cift kanalli pH monitorizasyonu etkin bir yontem teskil etmektedir.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128416623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Metin Erdinç, M. Gürbüz, Erkan Özüdoğru, Cemal Cingi, Hamdi Cakli, E. Kaya, Armaǧan Incesulu, Cem Keçik
{"title":"Vokal kord poliplerinde cerrahi tedavi sonrası ses kalitesinin değerlendirilmesi","authors":"Metin Erdinç, M. Gürbüz, Erkan Özüdoğru, Cemal Cingi, Hamdi Cakli, E. Kaya, Armaǧan Incesulu, Cem Keçik","doi":"10.2399/JMU.2012002005","DOIUrl":"https://doi.org/10.2399/JMU.2012002005","url":null,"abstract":"Objective: Endolaryngeal microsurgery is the fundamental treatment of vocal cord polyps. After surgical treatment, the changes in the voice quality can be measured by various scales that examine the audio perception of the voice and/or by objective voice analyses done with the help of a software program. The aim of this study was to evaluate the vocal performance of the patients with vocal cord polyps operated with endolaryngeal microsurgery. Methods: In this study, Vocal Performance Questionnaire and acoustic voice analyses were performed on 40 patients with vocal cord polyps operated with endolaryngeal microsurgery and the results were compared statistically. Results: When pre-, and postoperative comparisons of the parametres of the cases were evaluated statistically by Vocal Assessment program, a statistically significant decrease in postoperative Jitter (%), Shimmer (%), Fo tremor (Hz), noise energy (dB), harsh voice, hoarse voice, breathy voice parameters, while a statistically significant increase in percent voiceless, and voiced time during habitual phonation, fundamental frequency change interval (Hz) was detected. However in statistical comparisons of parameters using Real Analysis Program, a statistically significant decreases were detected in percent voiceless time during habitual phonation, fundamental frequency change interval (Hz), and percent voiceless time values between the lowest-, and the highest-pitched sounds that could be recorded during phonation after the treatment, while statistically significant increases in posttreatment percent voiced time during habitual phonation, percent voiced time values between the lowest-, and the highest-pitched sounds that could be recorded during phonation, and fundamental frequency change interval (Hz) were demonstrated. Conclusion: It has been conceived that the physiology of the larynx can be protected with a successful surgical excision and the phonatuary functions of the vocal cords can be returned to normal.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125867784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belgin Küçükgünay, Görkem Eskiizmir, H. Ünlü, Asım Aslan, Petek Bayindir, Gülgün Yilmaz Ovali, B. Özyurt
{"title":"Normal popülasyonda ve frontal rinosinüzitli olgularda resessus frontalisin anatomik varyasyonlarının radyolojik olarak değerlendirilmesi","authors":"Belgin Küçükgünay, Görkem Eskiizmir, H. Ünlü, Asım Aslan, Petek Bayindir, Gülgün Yilmaz Ovali, B. Özyurt","doi":"10.2399/JMU.2012002001","DOIUrl":"https://doi.org/10.2399/JMU.2012002001","url":null,"abstract":"Objective: In this study, we aimed to evaluate the anatomical variations around frontal recess and the influence of variations on frontal rhinosinusitis (FR) in healthy individuals and in cases with frontal rhinosinusitis (FR). Methods: A total of 61 cases that applied to our outpatient center were grouped according to: cases with ear complaints (Group I, control group), cases with sinonasal symptoms but FR findings (Group II), and cases with both sinonasal and FR findings (Group III). All cases underwent paranasal computerized tomography (CT) with parasagittal reconstruction. All scans were assessed for the presence of fronto-ethmoidal cells, anatomical variations, osteomeatal complex diseases and sinus opacifications. Results: In all sides of study, the rate of fronto-ethmoidal cell was 20.9%. When cases with sinonasal signs (Groups II and III) and control group (Group I) were compared, intersinus septum (p=0.01) and agger nasi cells (p=0.001) were statistically significant. In sides with frontal recess disease (+) and/or frontal sinus opacification (+), Kuhn type III (p=0.03) fronto-ethmoidal cells and bulla frontalis (p=0.02) were significantly increased, and Kuhn type IV fronto-ethmoidal cell (both sides) was present only in cases with frontal recess disease (+) and/or frontal sinus opacification (+). When the role of fronto-ethmoidal cells on frontal recess disease and/or frontal sinus opacification were assessed, Kuhn Type III cell was 4.55 times (%95 GS: 0.560-12.196) more effective. Conclusion: Kuhn type III and IV fronto-ethmoidal cells and bulla frontalis may have a role in FR. The radiological evaluation of anatomical variations around frontal recess with parasagittal sections was useful.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131109185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salim Yüce, Mansur Doğan, I. Uysal, Ayhan Dursun, Ismail Salk, E. Altuntaş
{"title":"Dev frontal piyomukosel","authors":"Salim Yüce, Mansur Doğan, I. Uysal, Ayhan Dursun, Ismail Salk, E. Altuntaş","doi":"10.2399/JMU.2012002008","DOIUrl":"https://doi.org/10.2399/JMU.2012002008","url":null,"abstract":"Giant mucoceles of the frontal sinus are rare but their recognition is important in the differential diagnosis of proptosis and fronto-orbital lesions. We describe a patient with frontal giant mucocele with intracranial as well as orbit and ethmoid sinus involvement. A 53-year-old male was admitted with headache, right exophthalmos and ophthalmoplegia. Computed tomography and magnetic resonance imaging demonstrated a giant frontal sinus mucocele with extension into the left anterior cranial fossa and orbit. The mucocele was treated with a transcranial and endoscopic transnasal approach.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128346843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tamponlu ve tamponsuz septoplasti uygulanan hastalarda postoperatif mukosiliyer klirens zamanının karşılaştırılması","authors":"I. Cukurova, Yusuf Yalçın, Hüseyin Kırşen","doi":"10.2399/JMU.2012001003","DOIUrl":"https://doi.org/10.2399/JMU.2012001003","url":null,"abstract":"Amac: Tamponlu ve tamponsuz septoplasti uygulanan hastalarda postoperatif mukosiliyer klirens zamanini karsilastirmak. Yontem: Bu calismaya nazal deviasyonu olan 20'si kadin, 26'si erkek, toplam 46 hasta alindi. Hastalara lokal anestezi altinda septoplasti ameliyati uygulandi. Hastalar 2 gruba ayrildi. Birinci gruba (28 hasta), septum stabilizasyonu icin her iki nazal pasaja Merocell® tampon yerlestirildi. Postoperatif 2. gun tamponlar cikarildi ve salin solusyonu ile irrigasyon baslandi. Ikinci gruba (18 hasta) septum stabilizasyonu icin transseptal sutur uygulandi ve postoperatif 6. saatte salin solusyonu ile irrigasyon baslandi. Tum hastalara preoperatif, postoperatif 1. hafta ve 3. ayda sakarin klirens testi uygulandi ve sonuclar karsilastirildi. Bulgular: 20-53 yaslari arasinda 46 hastaya ait preoperatif nazal mukosiliyer klirens zamani; birinci grupta deviye tarafta 14.65 dk, nondeviye tarafta 14.07 dk idi. Ikinci grupta deviye tarafta 11.9 dk, nondeviye tarafta 13.1 dk idi. Postoperatif 1. haftada mukosiliyer klirens zamani; birinci grupta deviye tarafta 12.54 dk, nondeviye tarafta 11.23 dk , ikinci grupta deviye tarafta 10.1 dk, nondeviye tarafta 10.8 dk saptandi. Postoperatif 3. ayda mukosiliyer klirens zamani; birinci grupta deviye tarafta 11.6 dk, nondeviye tarafta 10.4 dk , ikinci grupta deviye tarafta 6.76 dk, nondeviye tarafta 7.8 dk saptandi. Sonuc: Nazal septal deviasyon nedeni ile opere edilen hastalarimizin postoperatif donemdeki mukosiliyer klirens zamani degerlendirildi. Suturlu teknik ile opere ettigimiz grupta mukosiliyer klirens zamaninin, diger gruba oranla daha hizli oldugu tespit edilmistir.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"350 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116502480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gelişme evresindeki dergimiz: Journal of Medical Updates","authors":"Cemal Cingi","doi":"10.2399/JMU.2012001000","DOIUrl":"https://doi.org/10.2399/JMU.2012001000","url":null,"abstract":"Sizleri Journal of Medical Updates dergimizin ikinci cildinin ilk say›s›nda kucaklamaktan mutluluk ve onur duyuyorum. Baflkanl›¤›n› yapt›¤›m, Surekli E¤itim ve Bilimsel Araflt›rmalar Derne¤i (SEBAD), ad›ndan da anlafl›laca¤› gibi, e¤itim ve bilimsel cal›flmalar› destekleyen ve kar amac› gutmeyen bir kurulufltur. Bircok bilimsel toplant› duzenledikten sonra, bu dergiyi y›lda 3 say› frekans›nda yay›nlamaya karar verdik. Dergimiz tum KBB alanlar›n›n yan› s›ra alerji, pediatri, noroloji, noroflirurji, anesteziyoloji, radyoloji ve go¤us hastal›klar› gibi ilgili alanlar› da icine alacakt›r. Derginin resmi dili Turkce ve ‹ngilizce’dir. Yaz›lar bu dillerin birinde yaz›lacak ancak ozetler her iki dilde de yay›mlanacakt›r. Dergimizin dunyan›n ceflitli bolgelerinden secilmifl onde gelen araflt›rmac›lardan oluflan editorleri bulunmaktad›r. Nazik destekleri icin onlara flukran duymaktay›z. Dergi maceram›za gecen y›l sadece bas›l› yay›n olarak bafllasak da, gunun koflullar› gere¤i bundan sonraki yay›n yolculu¤umuza hem bas›l›, hem de cevrimici olarak devam etmeye karar verdik. Art›k tum yay›mlanm›fl tum makalelere web sitemizden (www.jmedupdates.org) ulafl›labilecektir. Yaz›lar›n ac›k eriflim yay›mlanmas› derne¤imizin bir e¤itim hizmeti olup, bircok ac›k eriflim dergisinin aksine, yazarlardan hicbir ucret talep edilmeyecektir. Dergimizin bu emekleme evresindeki titiz cal›flmalar› ile de¤erli katk›larda bulunan editor ekibine ve yay›mc›m›z Deomed’e teflekkurlerimi sunuyorum. Sizi ilk yaz›n›z› “Journal of Medical Updates” dergimize gondermeye davet ediyor, de¤erlendirme ve son karar surecinin gerekli titizlikte ama cok k›sa olaca¤›na soz veriyorum. Herhangi bir konuda veya dergimizde yaz› de¤erlendirmek icin lutfen benimle temasa gecmekte tereddut etmeyiniz.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130004419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Alerjik rinit ve astımda ortak tanı yöntemleri","authors":"A. B. Kavut, Füsun Kalpaklıoğlu","doi":"10.2399/JMU.2012001005","DOIUrl":"https://doi.org/10.2399/JMU.2012001005","url":null,"abstract":"The diagnosis of allergic airway diseases is based on symptoms, and the laboratory tests help us to classify the types. A correct diagnosis is important, since the treatment will change in different types of diseases. For example, untreated rhinitis may result in other diseases like asthma, and deteriorate the quality of life. Therefore, early diagnose of allergic airway diseases is important before the disease progresses. This review summarizes the currently known diagnostic tools which can be useful in daily practical life and researches, including assessment of symptoms, physical examination, allergy skin tests, total and specific IgE, nasal provocation test and assessment parameters (symptoms, nasal flow and secretions), nasal mucosal sampling, and pulmonary function test.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114331036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enfeksiyondan korunma ve immün sistem","authors":"Murat Songu, H. Katılmış","doi":"10.2399/JMU.2012001006","DOIUrl":"https://doi.org/10.2399/JMU.2012001006","url":null,"abstract":"Immune system is a sum of all processes which protect a living organism against diseases, also recognize, and destroy pathogens and tumor cells. Human body protects itself against bacteria, viruses, and other foreign substances via very diverse mechanisms. This protection involves physical barriers, fagocytic cells in blood, and tissues, and various molecules of hematologic origin. These mechanisms can be divided into two interdependent defense systems as non-specific or hereditary immune system and specific or acquired immune system. Non-specific immune system which is the first stage of the defense system discriminates between foreign substances and those belonging to the body, but it cannot distinguish between two types of pathogens. However, specific immune system can discern between those belonging or foreign to the organism, and responds specifically to different pathogens, and foreign molecules. The main objective of this paper is in general to deal with cells, molecules, and tissues involving in immune system, and define normal mechanisms used to defend the body against foreign substances.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127196284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cemal Cingi, Fatih Oğhan, H. Ünlü, A. Tekat, Şemsettin Okuyucu
{"title":"Alerjik rinitte montelukast ve desloratadin kombinasyonunun etkinliği","authors":"Cemal Cingi, Fatih Oğhan, H. Ünlü, A. Tekat, Şemsettin Okuyucu","doi":"10.2399/JMU.2011001001","DOIUrl":"https://doi.org/10.2399/JMU.2011001001","url":null,"abstract":"Allergic rhinitis represents a global health problem affecting 10 to 25% of the population worldwide. The complications i.e. sinusitis, nasal polyps, middle ear and lower respiratory tract infections increase the importance of allergic rhinitis. Besides treatment costs, due to wage loss and decrease in productive capacity it has a huge negative impact on community. It may also seriously affect quality of life. Despite recent developments in its treatment modalities, several studies have indicated that the prevalence of allergic rhinitis is increasing. New knowledge on the mechanisms underlying allergic inflammation of the airways has resulted in better therapeutic strategies for allergic rhinitis. Montelukast and desloratadine has powerful effects on allergic rhinitis. Since studies demonstrate that both products have better pharmacodynamic and pharmacokinetic profiles, and having side effects similar to placebo, they are better options for this sub-group. The concomitant use of both drugs is believed to provide a better control on the symptoms of allergic rhinitis. The combination therapy possibly provides a more potential reduction in early and late allergic and inflammatory response to histamine and histamine like mediators during allergen inhalation. Including a fixed dose combination of montolukast-desloratadine to the treatment strategy seems to be a more rational and cost effective approach in these groups of patients.","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116811838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}