Journal of Manipulative and Physiological Therapeutics最新文献

{"title":"Influence of Sex and Body Mass Index on the Thoracic Kyphosis and Lumbar Lordosis","authors":"Ana P.O.C. Miranda MS ,&nbsp;Patrícia J. Penha PhD ,&nbsp;Luciana G. Pereira ,&nbsp;Wallace C. Pessoa PT ,&nbsp;Sílvia M.A. João PhD","doi":"10.1016/j.jmpt.2022.12.001","DOIUrl":"10.1016/j.jmpt.2022.12.001","url":null,"abstract":"<div><h3>Objectives</h3><p>The purpose of this study was to assess the influence of sex and body mass index<span> (BMI) on the thoracic kyphosis<span> and lumbar lordosis of adolescents and to assess the reliability and agreement of the flexicurve method for these measurements.</span></span></p></div><div><h3>Methods</h3><p>The study included 217 adolescents of both sexes, aged between 11 and 15 years, who were students from municipal schools in the city of São José dos Campos in São Paulo. The measurement of thoracic kyphosis and lumbar lordosis angles was performed using the flexicurve method. Descriptive analysis of the data, analysis of covariance for comparison between groups (by BMI and sex), assessment of reliability, and intrarater agreement were analyzed.</p></div><div><h3>Results</h3><p>There was a significant difference between the groups by BMI and sex only for lumbar lordosis. The obese group had greater lumbar angles for both sexes (female sex: 32.6° ± 7.8° [eutrophic]; 37.7° ± 7.3° [obese]; male sex: 25.3° ± 7.3° [eutrophic]; 32.2° ± 7.3° [obese]). In the comparison between the sexes, the greatest lumbar angles were found in the female sex (female sex: 32.6° ± 7.8°; male sex: 25.3° ± 7.3°) among the eutrophic. Excellent intrarater reliability was found for thoracic kyphosis (intraclass correlation coefficient, 0.86) and moderate for lumbar lordosis (intraclass correlation coefficient, 0.72).</p></div><div><h3>Conclusion</h3><p>Sex and BMI were associated with lumbar lordosis in adolescents and were greater in individuals with obesity and female individuals. The flexicurve method was reliable and accurate for the assessment of thoracic kyphosis and lumbar lordosis in adolescents.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9252626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neck Strength Evaluated With Fixed and Portable Dynamometers in Asymptomatic Individuals: Correlation, Concurrent Validity, and Agreement","authors":"Tais S. Martins PT ,&nbsp;Carina F. Pinheiro-Araujo PT, PhD ,&nbsp;Camila Gorla PT, MSc ,&nbsp;Lidiane L. Florencio PT, PhD ,&nbsp;Jaqueline Martins PT, MSc ,&nbsp;César Fernández-de-las-Peñas PT, PhD ,&nbsp;Anamaria S. Oliveira PT, PhD ,&nbsp;Débora Bevilaqua-Grossi PT, PhD","doi":"10.1016/j.jmpt.2022.10.001","DOIUrl":"10.1016/j.jmpt.2022.10.001","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to assess the correlation, concurrent validity, and agreement between the isometric cervical force measurements obtained with fixed and portable dynamometers in asymptomatic individuals.</p></div><div><h3>Methods</h3><p>Fifty asymptomatic individuals performed 3 maximal isometric contractions<span><span> for flexion, extension, and lateral flexion of the cervical spine using fixed and portable dynamometers. The correlation and concurrent validity for the measurements of the portable and fixed dynamometers were analyzed using Spearman's </span>correlation coefficient and the intraclass correlation coefficient (ICC), respectively. The agreement between the force values of the portable and fixed dynamometers was measured using the Bland-Altman method.</span></p></div><div><h3>Results</h3><p>Isometric cervical force measurements obtained with the fixed dynamometer and portable dynamometer showed a moderately to highly significant correlation for flexion (r_s = 0.74), extension (r_s = 0.82), right lateral flexion (r_s = 0.74), and left lateral flexion (r_s = 0.68). The concurrent validity was moderate to good for all measurements (ICC_2,3 = 0.67-0.80). The fixed and portable dynamometers did not agree, with a significant mean difference between the methods of 2.8 kgf (95% confidence interval [CI], 2.1-3.4 kgf) for cervical flexion, 5.3 kgf (95% CI, 4.2-6.4 kgf) for extension, and 9.1 kgf (95% CI, 0.4-2.1 kgf) for left lateral flexion. The limits of agreement were broad for all movements, with errors that varied between 61% and 77% of the mean force obtained with the fixed dynamometer.</p></div><div><h3>Conclusion</h3><p>The neck strength measurements obtained with the fixed and portable dynamometers demonstrated high to moderate correlation and had moderate to good comparability for asymptomatic participants. However, they did not agree in that the 2 methods did not provide equivalent measurements, and, therefore, based on these findings, the same equipment should always be used when reassessing an individual.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9613786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects on Neuromuscular Function After Ischemic Compression in Latent Trigger Points in the Gastrocnemius Muscles: A Randomized Within-Participant Clinical Trial","authors":"Albert Pérez-Bellmunt PhD, PT ,&nbsp;Mathias Simon PT ,&nbsp;Carlos López-de-Celis PhD, PT ,&nbsp;Sara Ortiz-Miguel MSc, PT ,&nbsp;Vanessa González-Rueda PhD, PT ,&nbsp;César Fernandez-de-las-Peñas PhD, PT","doi":"10.1016/j.jmpt.2020.07.015","DOIUrl":"10.1016/j.jmpt.2020.07.015","url":null,"abstract":"<div><h3>Objective</h3><p><span><span><span>The purpose of this study was to evaluate changes in neuromuscular function, </span>pain perception<span>, and basic physical properties in latent myofascial trigger points (TrPs) after a single treatment session of </span></span>ischemic compression in the </span>gastrocnemius muscle.</p></div><div><h3>Methods</h3><p><span>A randomized within-participant clinical trial with a blinded assessor was conducted. Twenty-nine asymptomatic volunteers with latent gastrocnemius-muscle TrPs were bilaterally explored. Each extremity was randomly assigned to the control group (no treatment) or the experimental group (90 seconds of ischemic compression over each TrP). Neuromuscular function of the gastrocnemius muscle was assessed using a MyotonPro. Muscle flexibility was analyzed using the lunge test and the passive ankle range of motion. The strength was determined with a handheld </span>dynamometer<span><span> (MicroFET2). Pain perception was analyzed with a 0-to-10 numerical pain rating scale and determination of </span>pressure pain thresholds over each latent TrP.</span></p></div><div><h3>Results</h3><p>The results revealed a reduction of 15.8% in pain perception and an increment of pressure tolerance of 9.9% without pain in the treatment group. Changes in muscle flexibility (active and passive) and most parameters for neuromuscular response (rigidity, elasticity, and relaxation) were also observed, but they were not significantly different between groups. The clinical effect sizes were moderate for pain perception (<em>d</em> = 0.69), pressure pain threshold (<em>d</em> = 0.78), muscle tone (<em>d</em> = 0.51), and elasticity (<em>d</em> = 0.54) in favor of the treated extremity. Small clinical effect sizes were observed for muscle physical outcomes.</p></div><div><h3>Conclusion</h3><p>The present study shows that the use of a single session of ischemic compression for latent gastrocnemius-muscle TrPs improved some sensory outcomes. The effects on ankle range of motion and neuromuscular responses were inconclusive.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jmpt.2020.07.015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9243820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in Coracohumeral Distance Between the Symptomatic and the Asymptomatic Shoulder in Patients With Unilateral Shoulder Pain and in Healthy Participants: A Cross-Sectional Study","authors":"Santiago Navarro-Ledesma PhD ,&nbsp;Manuel Fernandez-Sanchez PhD ,&nbsp;Filip Struyf PhD ,&nbsp;Alejandro Luque-Suarez PhD","doi":"10.1016/j.jmpt.2022.10.004","DOIUrl":"10.1016/j.jmpt.2022.10.004","url":null,"abstract":"<div><h3>Objectives</h3><p>The aim of this study was to analyze whether differences in the coracohumeral distance (CHD) exist between the symptomatic and the asymptomatic shoulder in patients with subacromial pain syndrome and compare with the shoulder of control participants.</p></div><div><h3>Methods</h3><p><span>This was a cross-sectional, observational study. A sample comprising 62 participants with subacromial pain syndrome was recruited from 3 different primary care centers. The CHD was determined from standardized </span>ultrasonography measures performed on both shoulders at 0° and 60° of shoulder abduction, whereas the dominant arm was measured for the control participants.</p></div><div><h3>Results</h3><p>Statistically significant differences in CHD at 0° and 60° were found between the symptomatic and control shoulders (<em>P</em> = .011/<em>P</em><span> = .002) and between the contralateral asymptomatic shoulder and controls (</span><em>P</em> = .026/<em>P</em> = .007).</p></div><div><h3>Conclusion</h3><p>We found differences in CHD at 0° and 60° of shoulder elevation between both the affected and the nonaffected shoulders when compared with healthy shoulders. These results suggest that CHD may be a contributing factor in chronic shoulder pain.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9599146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Forces Exerted by a Chiropractor on Children and Adults During High-Speed, Low-Amplitude Spinal Manipulations: A Feasibility Study","authors":"Walter Herzog PhD ,&nbsp;Peter Kevorkian DC ,&nbsp;Brent Russell DC ,&nbsp;Joel Alcantara DC","doi":"10.1016/j.jmpt.2022.09.003","DOIUrl":"10.1016/j.jmpt.2022.09.003","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this study was to demonstrate that quantification of the forces exerted by a single chiropractor<span> on children and adults during high-velocity, low-amplitude spinal manipulations and the correlation of forces to age was feasible.</span></p></div><div><h3>Methods</h3><p><span>The force-time profiles of high-velocity, low-amplitude spinal manipulations were measured in 48 children (109 manipulations) ranging from 14 weeks to 17 years of age, and 20 adults (49 manipulations) in a clinical setting. The measurements were taken using a thin, flexible pressure pad. Outcome variables (peak forces, preload forces, thrust forces, thrust durations, rates of force application, and thrust impulses) were quantified and compared across age groups using Kruskal-Wallis testing with Dunn </span>post hoc analysis<span>. Outcome variables were fitted with best-fitting linear regressions with age as the dependent variable. The level of significance for all statistical tests was set a priori at α = 0.05.</span></p></div><div><h3>Results</h3><p>Most outcome variables increased with the age of the patient. Specifically, peak forces, thrust forces, and the rate of force application were positively correlated with age, while thrust durations remained constant across all ages and preload forces decreased slightly with patient age for cervical spine manipulations.</p></div><div><h3>Conclusion</h3><p>For this single chiropractor in private practice, the forces he used increased with the age of the patient, and he thus used lower forces in children than adults. This study shows that measuring the forces used by a chiropractor in clinical practice on patients with a range of ages was feasible.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44698896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Effect of Lumbosacral Orthosis and Abdominal Drawing-In Maneuver on Postural Control in Adults With Nonspecific Chronic Low Back Pain","authors":"Fábio Carlos Lucas de Oliveira PT, PhD ,&nbsp;Christian Larivière PhD ,&nbsp;Mathieu Dallaire PT, MSc ,&nbsp;Hakim Mecheri PhD ,&nbsp;Suzy Ngomo PT, PhD ,&nbsp;Rubens A. da Silva PT, PhD","doi":"10.1016/j.jmpt.2022.09.005","DOIUrl":"10.1016/j.jmpt.2022.09.005","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to examine the immediate effects of lumbosacral orthosis and the abdominal drawing-in maneuver on the trunk postural control of adults with chronic low back pain compared with asymptomatic controls during 1-legged and semi-tandem stances.</p></div><div><h3>Methods</h3><p>An experimental and comparative study (cross-sectional design) was conducted in a laboratory setting. Twenty adults with chronic low back pain and 20 asymptomatic controls randomly performed 2 postural balance tasks over a force platform, considering 3 experimental conditions: (1) natural posture (baseline-control), (2) lumbosacral orthosis, and (3) abdominal drawing-in maneuver. Linear variables (mean amplitude, ellipse area, and sway velocity) derived from the center of pressure were computed, and 2-way analysis of variance (group × condition) for repeated measures were conducted.</p></div><div><h3>Results</h3><p>No group × condition interactions (.139 ≤ <em>P</em> ≤.938) were detected in any center of pressure parameters. No condition effect was detected, but a group effect (<em>P</em> = .042) was observed for 1 center of pressure parameter. The chronic low back pain group presented with a lower mean anteroposterior center of pressure amplitude than asymptomatic controls (∆ = 0.31 ± 0.66 cm [95% confidence interval, 0.05-0.56], <em>P</em> = .019) during the semi-tandem stance balance task.</p></div><div><h3>Conclusion</h3><p>Neither lumbosacral orthosis nor the abdominal drawing-in maneuver showed immediate improvement in trunk postural control in any group. Thus, clinicians should not expect immediate benefits or improvements yielded by lumbosacral orthosis or the abdominal drawing-in maneuver when patients with chronic low back pain undergo these interventions.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10389938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Effects of Single-Session Proprioceptive Neuromuscular Facilitation Exercises on the Sit-to-Stand Strategy in Patients With Chronic Lumbar Spinal Disc Disease: A Preliminary Study","authors":"Tomasz Sipko PT,&nbsp;Edmund Glibowski PhD","doi":"10.1016/j.jmpt.2022.09.004","DOIUrl":"10.1016/j.jmpt.2022.09.004","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to measure the immediate effects of single-session proprioceptive neuromuscular facilitation<span> exercises on the sit-to-stand (STS) task and level of pain in patients with chronic low back pain.</span></p></div><div><h3>Methods</h3><p>Fifty-three patients were assigned to the control and intervention groups. The total time was 30 minutes (each exercise 5 minutes). The minimum vertical ground reaction force (VGRF_min) and maximum vertical ground reaction force (VGRF_max) and time phases (T_min – time to counterforce, T_max – time to peak force, T_tot<span> – time to post-peak rebound force) were measured with a Kistler force plate in eyes-open and eyes-closed conditions during the STS task. Pain level was determined on a numeric rating scale.</span></p></div><div><h3>Results</h3><p>Main effects were observed only in the intervention group: decreasing pain value (F = 25.398, <em>P</em> &lt; .0001), increasing T_min (F = 5.72, <em>P</em> = .0044), decreasing T_max (F = 3.43, <em>P</em> = .04), and decreasing T_tot (F = 3.935, <em>P</em> = .02258). There was a main effect of the eyes factor on VGRF_min (F = 12.53, <em>P</em> &lt; .0001) and VGRF_max (F = 7.16, <em>P</em> &lt; .01).</p></div><div><h3>Conclusion</h3><p>Immediate effects of single-session proprioceptive neuromuscular facilitation exercises were observed in decreasing the level of pain. Adaptation effects were noted in the retention test. The STS task could be optimized in time phases and dynamic movements in patients with chronic low back pain.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41382850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electromyographic Activity of Sternocleidomastoid Muscle in Individuals With Neck Pain and Healthy Volunteers: A Reliability and Between-Group Differences Examination","authors":"Fotios Iliopoulos MSc (PT) ,&nbsp;Zacharias Dimitriadis PhD ,&nbsp;George A. Koumantakis PhD","doi":"10.1016/j.jmpt.2022.09.001","DOIUrl":"10.1016/j.jmpt.2022.09.001","url":null,"abstract":"<div><h3>Objectives</h3><p>The purpose of this study was to evaluate the electromyographic activity of the sternocleidomastoid muscle during the performance of the craniocervical flexion test (CCFT) in individuals with neck pain and healthy volunteers, assess the reliability of this method, and examine possible between-population differences.</p></div><div><h3>Methods</h3><p>Electromyographic activity of the sternocleidomastoid muscles of 22 individuals with neck pain and 22 healthy participants was recorded during the 55 stages of the CCFT. Pain (visual analog scale) and disability (Neck Disability Index) levels and pain duration were recorded for the participants with neck pain. Reliability of electromyography<span> was evaluated with the intraclass correlation coefficient, standard error of measurement, and minimum detectable change.</span></p></div><div><h3>Results</h3><p>Within-day reliability indices of electromyographic activity were very good to excellent (intraclass correlation coefficients, 0.86-0.98; standard error of measurement, 1.8%-7.6%; minimum detectable change, 5.0%-21.1%). For the head-lift normalization method, 2-way analysis of variance revealed significant between-group differences (<em>P</em> &lt; .02); however, these were not clinically significant when reliability test-retest error was considered. Differences between contraction levels were significant (<em>P</em> &lt; .001); however, the group by contraction level interaction factor was nonsignificant. Therefore, the between-groups electromyographic increases noted with increasing contraction levels were similar. No correlation was identified between participants’ electromyography data and pain or disability.</p></div><div><h3>Conclusion</h3><p>In participants with moderate pain, disability, and pain duration, no clear alterations in electromyographic activity of the sternocleidomastoid could be detected with the CCFT. Reliability of the test used was very good.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10355162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Massage Therapy in Regulating Wnt/β-Catenin Pathway on Retarding Denervated Muscle Atrophy in Rabbits","authors":"Wei-feng Hu BM ,&nbsp;Ru-bao Guo MD","doi":"10.1016/j.jmpt.2022.09.002","DOIUrl":"10.1016/j.jmpt.2022.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to investigate the effect of massage therapy<span> on retarding denervated<span> muscle atrophy in rabbits.</span></span></p></div><div><h3>Methods</h3><p>The denervated skeletal muscle<span><span> atrophy rabbit model was established with the clamping rabbit tibial nerve<span> method. On the third and first day after clamping the rabbit tibial nerve, the model rabbits were treated with massage or nerve growth factor<span> (15 μg/mL) once a day for 8 weeks, respectively. Subsequently, gastrocnemius tissues were collected from rabbits and detected by </span></span></span>electromyography<span><span><span>. The gastrocnemius tissue sections were stained with hematoxylin<span> and eosin and Sirius red staining to evaluate the histopathologic damage of denervated muscle atrophy in a rabbit model. Furthermore, the proliferation and differentiation-related targets of satellite cells in gastrocnemius tissues were detected by immunohistochemical, </span></span>immunofluorescence, real-time </span>quantitative reverse transcription polymerase chain reaction<span>, and Western blot assays, respectively. Also, the effects of massage on the Wnt/β-catenin pathway were detected. Finally, gastrocnemius myocytes were isolated from rabbits to detect the expression levels of α-smooth muscle actin (α-SMA).</span></span></span></p></div><div><h3>Results</h3><p><span>The nerve conduction deteriorated continuously with time in model rabbits. Massage significantly ameliorated the pathologic damages and motor endplate microstructure of </span>gastrocnemius muscle<span><span>, effectively prevented fibrosis<span>, and regulated the proliferation and differentiation-related messenger RNA and protein expression of satellite cells with the time increased after denervation. Additionally, the number of differentiating satellite cells was increased after being treated with massage, and massage further kept </span></span>denervated muscles from atrophy. Importantly, the effect of massage to attenuate muscle atrophy was associated with the activation of the Wnt/β-catenin pathway. Meanwhile, massage reduced the expression of α-SMA in gastrocnemius myocytes.</span></p></div><div><h3>Conclusion</h3><p>This model demonstrated that massage delayed the atrophy of skeletal muscle. This was probably accomplished by regulating the proliferation and differentiation of the satellite cells via the Wnt/β-catenin signaling pathway.</p></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45694086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TOC","authors":"","doi":"10.1016/S0161-4754(22)00151-8","DOIUrl":"https://doi.org/10.1016/S0161-4754(22)00151-8","url":null,"abstract":"","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0161475422001518/pdfft?md5=40817c74e19dc0b7f58be17d9f29a799&pid=1-s2.0-S0161475422001518-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136822350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}