{"title":"Hypertriglyceridemia Induced Acute Pancreatitis in Pregnancy: A Case Report","authors":"A. Subedi, S. Gurung","doi":"10.22502/JLMC.V8I1.321","DOIUrl":"https://doi.org/10.22502/JLMC.V8I1.321","url":null,"abstract":"Introduction: Acute pancreatitis is a rare event in pregnancy. Hypertriglyceridemia induced acute pancreatitis accounts for the second most common cause in pregnancy. This rare event has a high maternal and fetal mortality of 20% and 50% respectively. Case report: A 21-year-old woman, G2P0+1 at 26 weeks period of gestation presented to OBGYN emergency in a state of shock with history of sudden onset of severe epigastric pain and multiple episodes of vomiting for one day and absent fetal movement for six hours. Immediate fluid resuscitation was done. Her reports showed increased hematocrit, leukocytosis, serum lipase and amylase elevated to > 200U/L. Ultrasonography showed bulky pancreas with intrauterine fetal death. With the diagnosis of acute pancreatitis with fetal demise, she was managed conservatively in intensive care unit by fasting, nasogastric aspiration, intravenous fluids, antibiotics, analgesics and heparin. She was intubated on the third day for increasing tachypnea. Her lipid profile showed elevated triglyceride> 1000 mg/dl and was started on oral hypolipidemic drugs. Pregnancy was terminated vaginally by misoprostol and was discharged on 19th day. Conclusion: Hypertriglyceridemia induced acute pancreatitis in pregnancy has an increased maternal and fetal complication.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"57 2","pages":"92-95"},"PeriodicalIF":0.0,"publicationDate":"2020-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141203813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paradigm Shift in Gynecological Surgeries Over Eight Years in Dhulikhel Hospital.","authors":"S. Tamrakar, B. Kayastha","doi":"10.22502/JLMC.V7I2.282","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.282","url":null,"abstract":"Introduction: One of the greatest achievements in the surgical field is the paradigm shift from opensurgery to minimal invasive surgery. Hysteroscopy, laparoscopy, laparoscopy-assisted vaginal hysterectomyand total laparoscopic hysterectomy are frequently performed minimal invasive gynecological surgeries.These surgeries are being regularly performed in Dhulikhel hospital. This study aims to review thechanges in surgical approaches in the field of gynecological surgeries in this institute. Methods: This was aretrospective study of changes in surgical approaches from conventional to minimal invasive surgery in thefield of gynecological surgeries from 2010 to 2018. Demographic characteristics of patients and indicationfor various minimal invasive surgeries were compared over this time period. Results: There were significantchanges in surgical approaches from conventional open surgeries to minimally invasive approach throughthe years. There was no obvious difference in demographic characteristics of the cases and the indications forhysterectomy and endometrial sampling were comparable. Conclusion: There was definitely paradigm shiftin conventional method to minimal invasive methods for major gynecological surgeries like hysterectomy,ovarian cystectomy, salpingectomy for ectopic pregnancy and endometrial samplings.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"70-75"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42640060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Axial Torsion and Meckel’s Diverticulitis: A Diagnostic Conundrum","authors":"S. Baral, R. Chhetri, Neeraj Thapa","doi":"10.22502/JLMC.V7I2.284","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.284","url":null,"abstract":"Introduction: Meckel’s diverticulum is one the most common congenital anomalies of gastrointestinal tract that mimics acute appendicitis, gastroenteritis, peptic ulcer disease. Complications related to it can be haemorrhage, intestinal obstruction, perforation while axial torsion is one of the rarest complications. So, this paper objectifies a rare clinical scenario that we encountered in our practice and highlights on the possible management strategies. Case : An 11 year boy presented with a history of pain at peri-umbilical region for four days with 2-3 episodes of vomiting. Abdominal examination revealed tenderness at suprapubic area with a mass around 5x3 cm along hypogastrium. Ultrasonography abdomen revealed an avascular structure in central area with clumping of bowel and omentum over the lesion while computed tomography scan of abdomen revealed blind ended gas filled structure at hypogastrium with thickened enhancing irregular wall associated with adjacent mesenteric fat plane stranding and prominent adjacent axial vessels supplying inflammatory lesion. Exploratory laparotomy showed axial twisting of diverticulum about 10x5 cm arising from anti-mesenteric border around 50 cm proximal to ileo-caecal junction with a fibrous band attached to the fundus and ileum leading to gangrenous diverticulum with clumping of bowel loops along with omental covering. De-twisting and adhesiolysis along with excision of the diverticulum was done with two layered closure of the defect. Conclusion: Axial torsion is the rarest of the complication of MD and should be managed with utmost caution. Excision of the twisted diverticulum with or without wedge resection of the involved ileum is the procedure of choice.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"113-115"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46319722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nasal Parameters and Facial Index in Medical Undergraduates: A Cross Sectional Study","authors":"S. Kc, Subina Shrestha, L. Bhattarai","doi":"10.22502/JLMC.V7I2.287","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.287","url":null,"abstract":"Introduction: Face has priority in identification of an individual. Nose occupying the middle of face is animportant sense organ that helps in respiration. Nose and face can be classified into different types accordingto nasal index and facial index. The aim of this study was to analyze nose and face type and find out itsdominance in different sex of Nepalese and Indian population. Methods: This was a quantitative observationalstudy conducted on 156 medical students using simple sampling method. Data were collected then nasalindex and facial index were calculated. Descriptive statistical data i.e. mean, standard deviation, togetherwith the independent-samples t-test results for anthropometric variables of nasal and facial parameters insex and Nationality (Nepalese and Indian) were analyzed. Results: All the measurement values were morein males compared to females, but the sexual dimorphism in nasal index (male 76.25 ± 7.75, female 75.70± 8.05) and facial index (male 85.77 ± 8.1, female 82.97 ± 7.63) is not statistically significant. Chi-squaretest revealed significant difference in face type among Nepalese and Indian population. Mesorrhine wasthe most common type of nose in both the population. Nepalese had commonly euryprosopic type of facewhile Indians had hypereuryprosopic type of face. Conclusion: Sexual dimorphism was not significant inboth nasal and facial parameters while type of face was helpful in differentiation of Nepalese and Indianpopulation.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"81-87"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48341504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinico-epidemiology of Hymenoptera Stings in and around Kaski District, Nepal.","authors":"S. Nepal, A. Atreya, T. Kanchan","doi":"10.22502/JLMC.V7I2.276","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.276","url":null,"abstract":"Introduction: In Nepal, morbidity and mortality from Hymenoptera stings is mainly from three commonly encountered insects: hornets (local: aringal), wasps (local: barulo) and honey bees (local: mahuri). The present study documents the incidence of hymenoptera sting in Western Region of Nepal and explores the cause behind such unprovoked attack upon human subjects. Methods: This hospital-based study included all the patients with history of insect sting attending the Emergency Department of Manipal Teaching Hospital, Pokhara from May 2015 till November 2015. Results: Of total 16 cases during the study period three were brought dead cases. The alleged insect happened to be bee in two cases, hornet in two cases, and wasp in eight cases with a case of unidentified insect sting. Severe burning pain with swelling, redness and itching were the common presenting symptom in all the admitted patients (n=13). Conclusion: Agricultural activity during the day was the cause of most unprovoked stings followed by deliberate destruction of the insect hive. Immediate medical attention in the nearby health care facility to the victims will save mortality. The health care facility also needs to have surplus lifesaving medication to counteract the life-threatening anaphylaxis reactions from such stings.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"50-55"},"PeriodicalIF":0.0,"publicationDate":"2019-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44121395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Otomycosis and its Predisposing Factors in Out-Patient Department of Otorhinolaryngology in a Tertiary Care Center","authors":"Bhuwan Raj Pandey, M. Singh, K. Bajracharya","doi":"10.22502/JLMC.V7I2.291","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.291","url":null,"abstract":"Introduction: Otomycosis is a fungal infection of external auditory canal frequently encountered by \u0000otorhinolaryngologists. It causes discomfort to patients with varied symptoms of pruritus, otorrhea, aural \u0000fullness and earache. People with a habit of using unnecessary ear drops, cleaning ear with unsterilized \u0000objects and those who use mustard oil are all prone to otomycosis. This study aims to find out the association \u0000between otomycosis and its predisposing factors. Methods: This study was undertaken in the Department of \u0000Otorhinolaryngology of a tertiary hospital from March 2018 to February 2019 and a total of 300 clinically \u0000diagnosed cases of otomycosis were enrolled for the study. Results: The mean age ±SD of the patients was \u000037.7 ± 18.8 years. Females (n=172, 57.3%) were more prone to otomycosis than males (n=128, 42.7%). The most common presenting symptom was pruritus only (n=95, 31.7%) with unilateral involvement being more common. The most common predisposing factor was mustard oil instillation (n=124, 41.3%). Aspergillus niger was the most common fungus causing otomycosis in this study (n=104, 34.7%). Positive fungal cultures were observed in 285 specimens (95%). The fungal growth (n=285) was high in patients with the history of instilling mustard oil (42.8%) into the ear, 34.0% in topical steroid containing ear drops and 23.2% in self-cleaning group. Conclusion: Otomycosis is common in people using unnecessary steroid containing ear drops, cleaning ear with unsterilized objects and instillation of mustard oil.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"76-80"},"PeriodicalIF":0.0,"publicationDate":"2019-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44546187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of Ultrasound Scan in Non-Traumatic Acute Abdomen Presenting in Surgery Department of a Tertiary Care Center","authors":"S. Acharya, A. Tiwari, Rupesh Sharma, S. Paudel","doi":"10.22502/JLMC.V7I2.293","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.293","url":null,"abstract":"Introduction: An acute abdomen is defined as a clinical condition characterized by severe abdominal pain developing suddenly over several hours or less. Ultrasonography (USG) helps the managing surgeons arrive at early diagnosis and rule out alternative diseases, thus reducing negative laparotomy rate. This study analyzed the diagnostic yield of USG in patients with non-traumatic acute abdomen presenting to Surgery department via Emergency department/outpatient department of a tertiary hospital. Methods: This cross-sectional observational study included 110 patients with non-traumatic acute abdominal pain who were sent for USG examination. The percentage concordance of USG diagnosis with the final diagnosis at discharge was determined in terms of sensitivity, specificity, positive and negative predictive values for acute abdomen. Results: Of 110 patients, correct clinical diagnosis was made in 83 patients (75%) while USG made a correct diagnosis in 101 patients (91%). Hence, with the help of USG, accuracy of diagnosing cause of acute abdomen increased by 16 %. The sensitivity and specificity of USG in diagnosis of acute appendicitis were 87.7% and 98.3% respectively. Conclusion: USG is easily available and non-invasive modality without radiation exposure and requiring minimal patient preparation. USG should, therefore, be an important routine diagnostic investigation in patients presenting with acute abdomen.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"56-60"},"PeriodicalIF":0.0,"publicationDate":"2019-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47983303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Shrestha, D. Mansur, D. K. Mehta, Sheprala Shrestha, Anupama Shrestha
{"title":"Variations of Nutrient Foramen of Femur and its Clinical Implications","authors":"P. Shrestha, D. Mansur, D. K. Mehta, Sheprala Shrestha, Anupama Shrestha","doi":"10.22502/JLMC.V7I2.270","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.270","url":null,"abstract":"Introduction: Nutrient foramen is the largest opening on the shaft of the femur that conveys nutrient artery into the marrow cavity. Knowledge on locations of nutrient foramina is essential during surgical procedures as well as to rule out if the fracture line passes through the foramina. The purpose of the study was to determine the number and position of nutrient foramina in relation to length and topography of the femur. Methods: The study model was descriptive, cross-sectional study that included 151 femurs (71 right and 80 left side). The total number, location, and direction of nutrient foramina were investigated. Total length of femur and distance of foramen from the proximal end was measured with the 500mm 20\" Digital Vernier Nib Jaw Caliper Metric/ Imperial Machine-DRO and finally Foraminal Index was calculated. Results: The analysis revealed 119(78.81%) of the femurs with single nutrient foramen, 31(20.52%) with double and 1(0.67%) with triple nutrient foramina. Foraminal Index II was found in 74(86.05%) on right side and 90(91.84%) on left side. The most common location of nutrient foramen was the medial lip of linea aspera (n= 77, 41.85%). All of the foramina were directed towards the proximal end. Conclusion: The present study has reported the majority of nutrient foramina located in the middle third of femur along the linea aspera. Thus, linea aspera should not be stripped off during surgical procedures to avoid damage to the nutrient arteries.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"61-64"},"PeriodicalIF":0.0,"publicationDate":"2019-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42626978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Tranexamic Acid in Reducing Blood Loss in Cesarean Section: A Comparative Study.","authors":"S. Acharya, S. Mishra","doi":"10.22502/JLMC.V7I2.292","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.292","url":null,"abstract":"Introduction: Obstetric hemorrhage is one of the major causes of maternal morbidity and mortality. Blood loss during cesarean section is almost twice than that in vaginal delivery. The aim of this study was to evaluate the efficacy of tranexamic acid to reduce blood loss in cesarean section and its side effects. Methods: A comparative study was done in 100 women undergoing cesarean section between December 2015 to January 2017. The study group of 50 women received one gram intravenous tranexamic acid and the control group of 50 women did not receive tranexamic acid. Primary outcome measure was blood loss during cesarean section. Secondary outcome measures were drop in post-operative hemoglobin and hematocrit, change in pulse rate and blood pressure, need of additional uterotonics, auxiliary procedures to stop bleeding, blood transfusion rate and maternal and neonatal side effects of the drug. Results: Mean intraoperative blood loss in the study group was 443.62± 86.73ml; and in control group, 667.40±131.01ml (p<0.001). Mean postoperative drop in hemoglobin (g/dl) in the two groups were 0.82±0.27 and 1.86±0.64 respectively (p<0.001). Mean postoperative drop in hematocrit in the two groups were 2.60±0.91 and 5.49±1.97 respectively (p<0.001). Fourteen patients in the control group required additional uterotonics while none in the study group (p<0.001). There was no significant difference in the transfusion requirement (p=0.079). None of the mothers and the newborns had major side effects of drug. Conclusion: Tranexamic acid is a safe and effective drug to reduce blood loss in cesarean section.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"44-49"},"PeriodicalIF":0.0,"publicationDate":"2019-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41774416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive Factors for Post-Operative Bleeding in Percutaneous Nephrolithotomy.","authors":"Neeraj Thapa, S. Baral, R. Chhetri, S. Paudel","doi":"10.22502/JLMC.V7I2.283","DOIUrl":"https://doi.org/10.22502/JLMC.V7I2.283","url":null,"abstract":"Introduction: Post-operative bleeding is a serious complication necessitating prompt attention inPercutaneous Nephrolithotomy (PCNL). A number of factors dictate the severity of post-PCNL bleeding.Identification of these risk factors helps prevent bleeding complications. Methods: In this observationalcross-sectional study, a total of 126 patients with renal stones >10mm or stag-horn stones underwent PCNL.All the relevant pre- and intra-operative factors were noted and analyzed. Hemoglobin differences betweenpre- and post-operative levels were considered for the evaluation of blood loss. Univariate and multivariablelogistic regression analysis was done. The strength of association was examined using Odds Ratio and95% confidence intervals derived from the logistic regression. A p value <0.05 was considered statisticallysignificant. Results: The mean age of the patients was 31.9 ±4.47 years. The mean drop in hemoglobinwas 1.83 ±0.98 gm/dl. Age, stone size, number of tracts, size of Amplatz sheath and number of stonessignificantly affected the blood loss in univariate analysis. Among the variables mentioned above only, thenumber of stones could maintain the significance in multivariable analysis (p<0.05). The number of stonesincrease the risk of bleeding post PCNL by 4.4 times. Conclusion: Stone size, number of tracts, size ofAmplatz sheath and the number of stones significantly affect the blood loss post PCNL. Identification ofthese risk factors should be considered for minimizing bleeding in PCNL.","PeriodicalId":16109,"journal":{"name":"Journal of Lumbini Medical College","volume":"7 1","pages":"65-69"},"PeriodicalIF":0.0,"publicationDate":"2019-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48514231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}