{"title":"Fate of Acute Cytomegalovirus Hepatitis in an Immune Competent Host","authors":"M. Asser","doi":"10.29199/cgdd.201013","DOIUrl":"https://doi.org/10.29199/cgdd.201013","url":null,"abstract":"Acute Cytomegalovirus (CMV) infections are widely distributed worldwide, with seroprevalance of 30-100% of general population, and a high rate of subclinical infections. Most of the cases pass silently, or complain of a group of non-specific symptoms that are usually mild and self-limited especially in immune competent individuals. Complications from acute CMV infections may rarely occur particularly in immune compromised individuals, affecting many organs including the liver, causing elevated liver Transaminases, jaundice and may even lead to acute liver failure requiring the use of antiviral therapy. In this case report, we describe a rare case of acute CMV hepatitis in a 34 years old immune competent male, who presented with fever, fatigue, elevated Transaminases and jaundice, which resolved completely without the need for antiviral therapy.","PeriodicalId":159300,"journal":{"name":"Journal of Clinical Gastroenterology and Digestive Disorders","volume":"175 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115186133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Duodenal Bezoar Following Pyloric-Exclusion Gastrojejunostomy","authors":"A. Maiti, Salahudeen, Goyal, E. Rahimi","doi":"10.29199/cgdd.101012","DOIUrl":"https://doi.org/10.29199/cgdd.101012","url":null,"abstract":"Bezoars are large aggregates of ingested material ranging from hair, fruit fibers, and others [1]. Radiographically, bezoars can mimic gastric neoplasms [2]. Complications from bezoars include small bowel obstruction to life-threatening bowel perforation [3]. Majority of patients with bezoars have some history of abdominal surgery [4,5]. While several cases of bezoars have been reported after gastro-duodenal surgeries, this is the first report of bezoar formation due to pyloric-exclusion gastrojejunostomy.","PeriodicalId":159300,"journal":{"name":"Journal of Clinical Gastroenterology and Digestive Disorders","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134488064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is There A Place for Systemic Chemotherapy and Targeted Agents in Metastatic Small Intestine Neuroendocrine Tumors?","authors":"K. Daskalakis, A. Tsolakis","doi":"10.29199/cgdd-101011","DOIUrl":"https://doi.org/10.29199/cgdd-101011","url":null,"abstract":"Neuroendocrine tumors (NETs) demonstrate a widely variable clinical behavior but in general they have an indolent clinical course. Small intestine NETs (SI-NETs) of Grades 1 and 2 have rather limited response rates to systemic chemotherapy of about 10%-30% [1-2]. Reports in the literature describe the low activity of chemotherapeutic drugs such as 5-FU/capecitabine given in combination to either oxaliplatin or dacarbazine/epirubicin or temozolomide [3-6]. Nevertheless, somatostatin analogs (SSAs) can control hormonal symptoms in the majority of the patients. Furthermore, SSAs show antiproliferative action. However, it is known that occasional well-differentiated SI-NETs may show a discrepancy between the proliferative index of the primary and the metastasis, necessitating the prompt initiation of systemic treatment [7].","PeriodicalId":159300,"journal":{"name":"Journal of Clinical Gastroenterology and Digestive Disorders","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115545892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}