Fate of Acute Cytomegalovirus Hepatitis in an Immune Competent Host

Acute Cytomegalovirus (CMV) infections are widely distributed worldwide, with seroprevalance of 30-100% of general population, and a high rate of subclinical infections. Most of the cases pass silently, or complain of a group of non-specific symptoms that are usually mild and self-limited especially in immune competent individuals. Complications from acute CMV infections may rarely occur particularly in immune compromised individuals, affecting many organs including the liver, causing elevated liver Transaminases, jaundice and may even lead to acute liver failure requiring the use of antiviral therapy. In this case report, we describe a rare case of acute CMV hepatitis in a 34 years old immune competent male, who presented with fever, fatigue, elevated Transaminases and jaundice, which resolved completely without the need for antiviral therapy.