Biotechnology to Combat COVID-19 [Working Title]最新文献

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Sensor Surface Design with NanoMaterials: A New Platform in the Diagnosis of COVID-19 纳米材料传感器表面设计:新冠肺炎诊断平台
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-03-29 DOI: 10.5772/INTECHOPEN.97056
Eliete A. Alvin, A. Borges, R. D. P. Martins, M. Lemes, R. M. Barbosa, C. J. Oliveira, Diógenes Meneses, B. G. Lucca, N. Dantas, V. R. Júnior, R. P. A. Balvedi, F. C. Abreu, Marcos Vinícius da Silva, Anielle C. A. Silva
{"title":"Sensor Surface Design with NanoMaterials: A New Platform in the Diagnosis of COVID-19","authors":"Eliete A. Alvin, A. Borges, R. D. P. Martins, M. Lemes, R. M. Barbosa, C. J. Oliveira, Diógenes Meneses, B. G. Lucca, N. Dantas, V. R. Júnior, R. P. A. Balvedi, F. C. Abreu, Marcos Vinícius da Silva, Anielle C. A. Silva","doi":"10.5772/INTECHOPEN.97056","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.97056","url":null,"abstract":"Mass testing for COVID-19 is essential to defining patient management strategies, choosing the best clinical management, and dimensioning strategies for controlling viral dissemination and immunization strategies. Thus, it is of utmost importance to search for devices that allow a quick and reliable diagnosis of low cost that can be transposed from the bench to the bedside, such as biosensors. These devices can help choose the correct clinical management to minimize factors that lead to infected patients developing more severe diseases. The use of nanomaterials to modify biosensors’ surfaces to increase these devices’ sensitivity and their biofunctionality enables high-quality nanotechnological platforms. In addition to the diagnostic benefits, nanotechnological platforms that facilitate the monitoring of anti-SARS-CoV-2 antibodies may be the key to determining loss of protective immune response after an episode of COVID-19, which leads to a possible chance of reinfection, as well as how they can be used to assess and monitor the success of immunization strategies, which are beginning to be administered on a large scale and that the extent and duration of their protection will need to be determined. Therefore, in this chapter, we will cover nanomaterials’ use and their functionalities in the surface design of sensors, thus generating nanotechnological platforms in the various facets of the diagnosis of COVID-19.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"133 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127363200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Different Therapeutic Strategies to Tackle the Infection Associated with COVID-19 应对COVID-19相关感染的不同治疗策略
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-03-24 DOI: 10.5772/INTECHOPEN.96899
Meemansha Sharma, Thakur Uttam Singh, Madhu Cholenahalli Lingaraju, S. Parida
{"title":"Different Therapeutic Strategies to Tackle the Infection Associated with COVID-19","authors":"Meemansha Sharma, Thakur Uttam Singh, Madhu Cholenahalli Lingaraju, S. Parida","doi":"10.5772/INTECHOPEN.96899","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96899","url":null,"abstract":"Covid-19 is a pandemic and the whole world is facing the loss in terms of morbidity and mortality of the human resources. Therefore, there is an urgent need for various therapeutic agents or drugs to treat the covid-19 patients. Although, vaccination process is under way, it is not possible to provide the vaccination to whole world in a short period. Therefore, it is an essential strategy to work on the various therapeutic aspects of covid-19 treatment. The present book chapter will discuss and review the various aspects of the treatment strategies of the covid-19. Further, we will provide an overview of the virus and host based potential therapeutic targets along with existing therapeutics which are effective against SARS-CoV-2 virus. Also, the novel vaccines are being developed against covid-19 deadly virus will be discussed.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130726515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Qualitative Study of Pre-Vaccine Decrease of Mortality from COVID-19 疫苗接种前降低COVID-19死亡率的定性研究
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-03-23 DOI: 10.5772/INTECHOPEN.97017
V. Mammadov, L. Jafarova
{"title":"A Qualitative Study of Pre-Vaccine Decrease of Mortality from COVID-19","authors":"V. Mammadov, L. Jafarova","doi":"10.5772/INTECHOPEN.97017","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.97017","url":null,"abstract":"More than a year has passed since the appearance of disease called COVID-19 in the world. This disease became the reason for unprecedented measures taken so far, having received the classification of pandemic. The world has faced with pandemics before, but society has not yet taken such unprecedented restrictive measures. The restrictions of not only local but even of global nature, such as the suspension of international flights, various scientific and political events were adopted around the world. Media resources have played a key role in the formation and development of the attitude towards the disease in people. Despite all the depressing news, the facts showed a low mortality rate, which is often ignored by the media. As a result, medical staff around the world have faced psychological health issues among the different groups of the population, especially vulnerable ones such as people with chronic disease and with weak immunity. At present, it is early to talk about the results and outcomes of the pandemic. However, previous year has taught us many lessons and can become a key factor in understanding the role of the media in pandemic times, developing strategies for combating diseases and protecting public health.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114648297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Development of RT-PCR Based Diagnosis of SARS-CoV-2 基于RT-PCR诊断SARS-CoV-2的研究进展
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-03-16 DOI: 10.5772/INTECHOPEN.96823
Rutuja Sunil Patankar, V. Zambare
{"title":"Development of RT-PCR Based Diagnosis of SARS-CoV-2","authors":"Rutuja Sunil Patankar, V. Zambare","doi":"10.5772/INTECHOPEN.96823","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96823","url":null,"abstract":"In the 2020, COVID-19 pandemic disease created an havoc situation world widely and mainly caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). It has been challenging task for researchers, scientists and medico-pharmaceutical organisations to find out rapid and reliable diagnosis methods. Among the all testing services, a Reverse Transcription Polymerase Chain Reaction (RT-PCR) is the more accurate, rapid and authenticated molecular technique used for most of the diagnosis of major diseases. It has been a global priority to fix the rapid diagnosis method to combat against the pandemic COVID-19. Thus, the present chapter mainly focussing on the progress of RT-PCR method development though various processes of data collection on isolation of whole genome sequence, its primer and method designing. In this scenario, India suddenly become the global leader for vaccine development and hence the challenges and RT-PCR kit development in India and rest of the world has been be discussed. World wide many Government and private agencies and industries have taken an initiative for diagnosis of SARS-CoV-2 hence this chapter also summarised the scope of RT-PCR to combat pandemic situation in future.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128597992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
The Link between Electrical Properties of COVID-19 and Electromagnetic Radiation COVID-19电学特性与电磁辐射之间的联系
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-03-14 DOI: 10.5772/INTECHOPEN.96815
Awaad K. Al Sarkhi
{"title":"The Link between Electrical Properties of COVID-19 and Electromagnetic Radiation","authors":"Awaad K. Al Sarkhi","doi":"10.5772/INTECHOPEN.96815","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96815","url":null,"abstract":"The ability of a new vaccine design based on control the intracellular physiological consequences of both the electrical properties and the electromagnetic radiation interactions between a virus and a host cell, which is a method to strengthen immune system develop protection against COVID-19 and new strains. The capacity of COVID-19 to bind to angiotensin-converting enzyme 2 (ACE2) and immune evasion mechanisms are only one of the properties required to stimulate a preventative immune response. In this chapter, a multidimensional new strategy is used to exemplify the empowerment function intracellular and extracellular level information can play in the support of immunogen against COVID-19 pathogens. Besides during this chapter, the nature of electromagnetic radiation is described as a vibrating string based on a string-theory and unification of electromagnetic radiation and gravitational waves by supporting with multiple cites strong evidence. Overall, we demonstrate a new approach to understand the important role of the physiological consequences of the interplay between the immune system and COVID-19 and designing vaccine strategy immunogens that take advantage of that information against COVID-19 and new strains.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129702012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cellular Therapy as Promising Choice of Treatment for COVID-19 细胞疗法是治疗COVID-19的有希望的选择
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-03-13 DOI: 10.5772/INTECHOPEN.96900
Duygu Koyuncu Irmak, E. Karaoz
{"title":"Cellular Therapy as Promising Choice of Treatment for COVID-19","authors":"Duygu Koyuncu Irmak, E. Karaoz","doi":"10.5772/INTECHOPEN.96900","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96900","url":null,"abstract":"In the pandemic of COVID-19, while living normals have been changing, there have been a huge effort globally to find out effective and safe treatment agents and vaccines. As of now, the advances show the progress in vaccine development, however the treatment of the COVID-19 is yet not fully specified. The drugs, i.e. antibiotics, antivirals, antimalarians, even anti-HIV agents which have been known already were taken out of the shelves and brought into use in different combinations. On the other hand, the cellular treatment, more specifically the mesenchymal stem cell therapy has been encouraged, resulting in various evidence published all over the world. This chapter aims to compile the published information, in means of methods, disease manifestations, results and limitations, about the stem cell treatment of the COVID-19 and to provide a source of harmonized reference for scientific society.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133595354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Whole Genome Sequencing: A Powerful Tool for Understanding the Diversity of Genotypes and Phenotypes among COVID-19 Infected Patients to Help in Controlling Outbreaks 全基因组测序:了解COVID-19感染患者基因型和表型多样性以帮助控制疫情的有力工具
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-02-15 DOI: 10.5772/INTECHOPEN.96260
Rayan A. Ahmed
{"title":"Whole Genome Sequencing: A Powerful Tool for Understanding the Diversity of Genotypes and Phenotypes among COVID-19 Infected Patients to Help in Controlling Outbreaks","authors":"Rayan A. Ahmed","doi":"10.5772/INTECHOPEN.96260","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96260","url":null,"abstract":"In Wuhan, China (December 2019), viral pneumonia cases of uncertain origin have been reported. The emergency has drawn global attention. To determine the pathogenic potential, joint efforts were conducted by Chinese Multidisciplinary Task Forces. An integral component of wide range of research applications is not only determining the causative agent but also the nucleic acid bases order in biological samples. Research techniques determining genetic material features and its order is called “sequencing”, classified into three generations. Moreover, the first sequencing attempt was conducted and a genetic link identified between samples isolated from China and other previously sequenced Coronaviruses. However, there was patient to patient diversity in terms of clinical and laboratory manifestations and diseases severity. After the genetic material of the causative agent was successfully sequenced, it was named the novel coronavirus causing COVID-19. Here, we review the genome sequences of novel coronavirus infected patients from different countries such as India, Bangladesh and Ecuador compared to China (first reported case), seeking not only to recognize similarities and differences between genome sequences of novel coronavirus, but also to compare them with other forms of coronaviruses family. Utilizing this data will assist in making right decisions minimizing negative consequences of the outbreak.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"17 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120858914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology, Pathogenesis, and Healing Strategies of COVID-19 COVID-19的流行病学、发病机制和治疗策略
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 2021-02-11 DOI: 10.5772/INTECHOPEN.96200
B. Bhowmik
{"title":"Epidemiology, Pathogenesis, and Healing Strategies of COVID-19","authors":"B. Bhowmik","doi":"10.5772/INTECHOPEN.96200","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96200","url":null,"abstract":"In the present chapter, some notable features (epidemiology, pathogenesis, and clinical characteristics) regarding recent outbreak COVID-19 have been reviewed. Most significant features related to COVID-19 such as (i) roots of infection and disease manifestation, (ii) shape and structure of viral S-protein, (iii) genome sequence study and replication in host cell, (iv) role of environmental factors, (v) diagnosis tools and (vi) role of biosensor have been critically investigated. The biological and behavioral risk factors for pregnant women before and after child birth have been dictated clearly. Pulmonary abnormalities due to COVID-19 of the patient having diabetes, cancer etc. history have been clarified with help of CT imaging. Finally, prevention and cure strategies adopted by many health professionals based on the existing drugs are mentioned with their side effects.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127124482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 and Cancer: Biological Interconnection and Treatment COVID-19和癌症:生物互联和治疗
Biotechnology to Combat COVID-19 [Working Title] Pub Date : 1900-01-01 DOI: 10.5772/intechopen.97482
N. Jyotsana
{"title":"COVID-19 and Cancer: Biological Interconnection and Treatment","authors":"N. Jyotsana","doi":"10.5772/intechopen.97482","DOIUrl":"https://doi.org/10.5772/intechopen.97482","url":null,"abstract":"The COVID-19 pandemic has affected more than 125 million lives worldwide and more than 2.5 million people have died so far. Cancer in itself increases the risk of infection especially, cancer patients undergoing cancer-associated treatments are more susceptible to SARS-CoV2 infection. However, many questions related to the biological interconnection between the two diseases remain to be answered. This chapter summarizes some of the biological components that connect cancer to COVID-19 and provide knowledge to not only understand but also, target the co-morbidities.","PeriodicalId":159296,"journal":{"name":"Biotechnology to Combat COVID-19 [Working Title]","volume":"279 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123138217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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