Journal of Failure Analysis and Prevention最新文献

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Primary nasal viral infection rewires the tissue-scale memory response. 原发性鼻腔病毒感染重塑了组织规模记忆反应。
Journal of Failure Analysis and Prevention Pub Date : 2024-03-18 DOI: 10.1101/2023.05.11.539887
Samuel W Kazer, Colette Matysiak Match, Erica M Langan, Marie-Angèle Messou, Thomas J LaSalle, Elise O'Leary, Jessica Marbourg, Katherine Naughton, Ulrich H von Andrian, Jose Ordovas-Montanes
{"title":"Primary nasal viral infection rewires the tissue-scale memory response.","authors":"Samuel W Kazer, Colette Matysiak Match, Erica M Langan, Marie-Angèle Messou, Thomas J LaSalle, Elise O'Leary, Jessica Marbourg, Katherine Naughton, Ulrich H von Andrian, Jose Ordovas-Montanes","doi":"10.1101/2023.05.11.539887","DOIUrl":"10.1101/2023.05.11.539887","url":null,"abstract":"<p><p>The nasal mucosa is frequently the initial site of respiratory viral infection, replication, and transmission. Recent work has started to clarify the independent responses of epithelial, myeloid, and lymphoid cells to viral infection in the nasal mucosa, but their spatiotemporal coordination and relative contributions remain unclear. Furthermore, understanding whether and how primary infection shapes tissue-scale memory responses to secondary challenge is critical for the rational design of nasal-targeting therapeutics and vaccines. Here, we generated a single-cell RNA-sequencing (scRNA-seq) atlas of the murine nasal mucosa sampling three distinct regions before and during primary and secondary influenza infection. Primary infection was largely restricted to respiratory mucosa and induced stepwise changes in cell type, subset, and state composition over time. Type I Interferon (IFN)-responsive neutrophils appeared 2 days post infection (dpi) and preceded transient IFN-responsive/cycling epithelial cell responses 5 dpi, which coincided with broader antiviral monocyte and NK cell accumulation. By 8 dpi, monocyte-derived macrophages (MDMs) expressing <i>Cxcl9</i> and <i>Cxcl16</i> arose alongside effector cytotoxic CD8 and <i>Ifng</i>-expressing CD4 T cells. Following viral clearance (14 dpi), rare, previously undescribed <b>K</b>rt13+ <b>n</b>asal <b>i</b>mmune-<b>i</b>nteracting <b>f</b>loor <b>e</b>pithelial (KNIIFE) cells expressing multiple genes with immune communication potential increased concurrently with tissue-resident memory T (T<sub>RM</sub>)-like cells and early IgG+/IgA+ plasmablasts. Proportionality analysis coupled with cell-cell communication inference, alongside validation by in situ microscopy, underscored the CXCL16-CXCR6 signaling axis between MDMs and effector CD8 T cells 8dpi and KNIIFE cells and T<sub>RM</sub> cells 14 dpi. Secondary influenza challenge with a homologous or heterologous strain administered 60 dpi induced an accelerated and coordinated myeloid and lymphoid response without epithelial proliferation, illustrating how tissue-scale memory to natural infection engages both myeloid and lymphoid cells to reduce epithelial regenerative burden. Together, this atlas serves as a reference for viral infection in the upper respiratory tract and highlights the efficacy of local coordinated memory responses upon rechallenge.</p>","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77071788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Fatigue Life of Gas Metal Arc and Friction Stir Welded AA 6061-T651 Aluminium Alloy Joints: A Comparative Investigation 评估气体金属弧焊和搅拌摩擦焊 AA 6061-T651 铝合金接头的疲劳寿命:比较研究
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2024-01-10 DOI: 10.1007/s11668-023-01845-y
Hemendra Kumar Srivastava, V. Balasubramanian, S. Malarvizhi, A. G. Rao
{"title":"Assessment of Fatigue Life of Gas Metal Arc and Friction Stir Welded AA 6061-T651 Aluminium Alloy Joints: A Comparative Investigation","authors":"Hemendra Kumar Srivastava, V. Balasubramanian, S. Malarvizhi, A. G. Rao","doi":"10.1007/s11668-023-01845-y","DOIUrl":"https://doi.org/10.1007/s11668-023-01845-y","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"45 14","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139440951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contact Welding Failure Analysis of Micro Electromagnetic Relays in Electrical Endurance Experiments 电气耐久性实验中微型电磁继电器的接触焊接故障分析
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2024-01-07 DOI: 10.1007/s11668-023-01846-x
Chao Zhang, Zhe Zheng, Wanbin Ren, Jian Liu, Xiu-qin Liu
{"title":"Contact Welding Failure Analysis of Micro Electromagnetic Relays in Electrical Endurance Experiments","authors":"Chao Zhang, Zhe Zheng, Wanbin Ren, Jian Liu, Xiu-qin Liu","doi":"10.1007/s11668-023-01846-x","DOIUrl":"https://doi.org/10.1007/s11668-023-01846-x","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"26 12","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139448481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrosion Failure Analysis of a S135 Drill Pipe S135 钻杆的腐蚀失效分析
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2024-01-05 DOI: 10.1007/s11668-023-01819-0
Jinlan Zhao, Xiaoliang Bai, Tingting Qu, Dongfeng Li, Wenhong Liu, Zunyi Wei, Xiaolong Li
{"title":"Corrosion Failure Analysis of a S135 Drill Pipe","authors":"Jinlan Zhao, Xiaoliang Bai, Tingting Qu, Dongfeng Li, Wenhong Liu, Zunyi Wei, Xiaolong Li","doi":"10.1007/s11668-023-01819-0","DOIUrl":"https://doi.org/10.1007/s11668-023-01819-0","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"54 24","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139384283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metallurgical Failure Analysis of Economizer Tube of Thermal Power Plant 火力发电厂经济器管的冶金失效分析
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2024-01-02 DOI: 10.1007/s11668-023-01837-y
Md Murtuja Husain, V. Rajinikanth, Parikshit Munda
{"title":"Metallurgical Failure Analysis of Economizer Tube of Thermal Power Plant","authors":"Md Murtuja Husain, V. Rajinikanth, Parikshit Munda","doi":"10.1007/s11668-023-01837-y","DOIUrl":"https://doi.org/10.1007/s11668-023-01837-y","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"112 50","pages":"1-16"},"PeriodicalIF":1.2,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Electrochemical Hydrogen Charging on Hydrogen Embrittlement and Mechanical Properties of Quenched Tempered X100 Pipeline Steel 电化学充氢对淬火回火 X100 管线钢的氢脆和机械性能的影响
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2023-12-31 DOI: 10.1007/s11668-023-01841-2
Reza Khatib Zadeh Davani, E. Entezari, M. Mohtadi-Bonab, Sandeep Yadav, Jhon Freddy Aceros Cabezas, Jerzy A. Szpunar
{"title":"Effect of Electrochemical Hydrogen Charging on Hydrogen Embrittlement and Mechanical Properties of Quenched Tempered X100 Pipeline Steel","authors":"Reza Khatib Zadeh Davani, E. Entezari, M. Mohtadi-Bonab, Sandeep Yadav, Jhon Freddy Aceros Cabezas, Jerzy A. Szpunar","doi":"10.1007/s11668-023-01841-2","DOIUrl":"https://doi.org/10.1007/s11668-023-01841-2","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"115 51","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139134204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pitting Corrosion of S13Cr Tubing in a Gas Field: A Failure Case and Corrosion Mechanism Analysis 气田中 S13Cr 油管的点腐蚀:失效案例与腐蚀机理分析
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2023-12-31 DOI: 10.1007/s11668-023-01843-0
Jinxing Yao, Xiankang Zhong, Qi Xiong, Jiansheng Yu, Duo Hou, Zhe Wang, Taihe Shi
{"title":"Pitting Corrosion of S13Cr Tubing in a Gas Field: A Failure Case and Corrosion Mechanism Analysis","authors":"Jinxing Yao, Xiankang Zhong, Qi Xiong, Jiansheng Yu, Duo Hou, Zhe Wang, Taihe Shi","doi":"10.1007/s11668-023-01843-0","DOIUrl":"https://doi.org/10.1007/s11668-023-01843-0","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"104 6","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139134798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental Study on Brittle Fracture Mechanism and Mechanical Properties of HRB400E Rebar Cross-Spot Welding HRB400E 钢筋交叉点焊接的脆性断裂机理和力学性能实验研究
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2023-12-31 DOI: 10.1007/s11668-023-01844-z
Dongdong Li, Kuankuan Xu, Xianzhong Zhang, Qingfeng Ding
{"title":"Experimental Study on Brittle Fracture Mechanism and Mechanical Properties of HRB400E Rebar Cross-Spot Welding","authors":"Dongdong Li, Kuankuan Xu, Xianzhong Zhang, Qingfeng Ding","doi":"10.1007/s11668-023-01844-z","DOIUrl":"https://doi.org/10.1007/s11668-023-01844-z","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":" 1007","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139136337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Failure Analysis of Fuel-Film Cooling Assembly of Reaction Control System for Satellite 卫星反应控制系统燃料膜冷却组件的故障分析
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2023-12-29 DOI: 10.1007/s11668-023-01840-3
Madni Shifa, F. Tariq
{"title":"Failure Analysis of Fuel-Film Cooling Assembly of Reaction Control System for Satellite","authors":"Madni Shifa, F. Tariq","doi":"10.1007/s11668-023-01840-3","DOIUrl":"https://doi.org/10.1007/s11668-023-01840-3","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":" 14","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139143044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Failure Analysis of the M5-Brass Shear Screw Used in an Aerospace Ordinance Applications 航空航天条例应用中使用的 M5-黄铜剪切螺钉的失效分析
IF 1.2
Journal of Failure Analysis and Prevention Pub Date : 2023-12-26 DOI: 10.1007/s11668-023-01839-w
Lagudu Yerrinaidu, R. Ranjith, Sushant K. Manwatkar, R. Gupta
{"title":"Failure Analysis of the M5-Brass Shear Screw Used in an Aerospace Ordinance Applications","authors":"Lagudu Yerrinaidu, R. Ranjith, Sushant K. Manwatkar, R. Gupta","doi":"10.1007/s11668-023-01839-w","DOIUrl":"https://doi.org/10.1007/s11668-023-01839-w","url":null,"abstract":"","PeriodicalId":15843,"journal":{"name":"Journal of Failure Analysis and Prevention","volume":"77 4","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139156850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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