Journal of Diabetology最新文献_第3页

The hidden obstacles to intranasal insulin delivery: A narrative review 鼻内胰岛素输送的隐性障碍:叙述性回顾

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_108_22

Ujjawal Rawat, Ambika Choudhary, P. Mittal, A. Verma

引用次数: 0

Platelet indices as a predictor of microvascular complications of type 2 diabetes mellitus 血小板指数作为2型糖尿病微血管并发症的预测指标

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_129_22

P. Agrawal, Shoorvir Singh, Akhilesh K Singh, N. Pursnani, Chandan K Keshari, A. Gautam, Harendra Kumar

引用次数: 0

Glucagon and cardiovascular disease 胰高血糖素和心血管疾病

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_94_23

Nagendra Kumar Singh, Banshi Saboo, Sanjeev Phatak, Samuel Seidu, Viral Shah, Wasim Hanif, Asher Fawwad

引用次数: 0

Glucagon-related advancements in diabetes therapy 与胰高血糖素相关的糖尿病治疗进展

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_96_23

Binayak Sinha, Samit Ghosal, Satinath Mukhopadhyay, Akhtar Hussain, Anjana Ranjit Mohan, Peter Schwarz, Francesc Xavier Cos Xavier

引用次数: 0

Prevalence of and risk factors for diabesity in urban Chennai 金奈城市糖尿病患病率及危险因素分析

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_121_22

Aarthi Raveendiran, R. Pradeepa, Venkatesan Ulagamathesan, J. Chambers, V. Mohan, P. Venkatasubramanian, A. Mohan

{"title":"Prevalence of and risk factors for diabesity in urban Chennai","authors":"Aarthi Raveendiran, R. Pradeepa, Venkatesan Ulagamathesan, J. Chambers, V. Mohan, P. Venkatasubramanian, A. Mohan","doi":"10.4103/jod.jod_121_22","DOIUrl":"https://doi.org/10.4103/jod.jod_121_22","url":null,"abstract":"Background: A large number of epidemiologic studies across the world indicate a growing link between obesity and diabetes. The metropolitan city of Chennai in South India is experiencing an alarming increase in diabetes and obesity. Aim: The aim of this study was to determine the prevalence of and risk factors for diabetes and obesity together termed as “diabesity” among adults in urban Chennai. Materials and Methods: This was a community-based cross-sectional door-to-door study done as part of a large National Institute of Health and Care Research (NIHR)––a funded project aimed to understand patterns and determinants of health in South Asia. Of the 200 wards in Chennai, 34 wards were surveyed in the main project and two wards were selected randomly for this substudy. Five community enumeration blocks were selected using a systematic sampling technique. Participants aged ≥18 years were selected using a consecutive sampling method. Results: Of the 1138 participants studied, the prevalence of diabesity was found to be 34.3%(n = 390). Of the study participants, 74.8% had obesity (61.9%––generalized obesity; 68.5%––abdominal obesity) and 43.0% had diabetes. As age increased, the diabesity risk also increased gradually from 30 to 39 years (odds ratio [OR]: 3.6[95%, confidence interval [CI]: 1.4–8.9]) to 50–59 years (OR: 5.4[95%, CI: 2.2–13.2]), whereas there was a slight decrease in risk after 60 years (OR: 5.1[95%, CI: 2.1–12.3]). Females had nearly twice the risk of diabesity compared to men (OR: 1.8, P < 0.001), and physically inactive individuals had 1.7 times increased risk (P < 0.001). Conclusion: We report in this study that the prevalence of the dual metabolic defect (diabesity) is alarmingly high in urban Chennai. This study was an attempt to understand the epidemiology of diabesity.","PeriodicalId":15627,"journal":{"name":"Journal of Diabetology","volume":"188 1","pages":"34 - 40"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74421191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and validation of treatment adherence scale for type 2 diabetes mellitus 2型糖尿病治疗依从性量表的研制与验证

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_126_22

Vallari Jadav, Hetal K Rathod, Sudhir Jadhav, Anil D. Mahajan, Deepu Palal, N. Borah, Prerna Verma, Sheri DeBoe Johnson, Gracia Sohkhlet, Sandeep Nallapu

引用次数: 0

Management of type 2 diabetes: Self-management education and clinical findings 2型糖尿病的管理:自我管理教育和临床结果

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_20_23

Aysun Türe, Nilufer Demirsoy, Deniz Gökalp

{"title":"Management of type 2 diabetes: Self-management education and clinical findings","authors":"Aysun Türe, Nilufer Demirsoy, Deniz Gökalp","doi":"10.4103/jod.jod_20_23","DOIUrl":"https://doi.org/10.4103/jod.jod_20_23","url":null,"abstract":"Abstract Aim: The purpose of this study is to determine the effects of the self-management education provided to patients with type 2 diabetes under the leadership of a nurse on the perceptions of self-management and clinical findings of patients. Materials and Methods: The sampling of the research comprises 281 patients who received a diagnosis of type 2 diabetes and whose treatment is being conducted. The self-management perceptions, body mass index, preprandial blood glucoses, and glycolyzed hemoglobin levels of the patients were measured before and after the intervention and 3 months later. Results: It was determined as a result of the comparison of the scores before and after the nursing education provided to the patients that the patients’ self-management perception scale scores increased significantly and that the body mass index, preprandial blood glucose, and glycolyzed hemoglobin levels reduced significantly ( P < 0.01). Conclusions: It is determined in research that the self-management education provided to patients with type 2 diabetes under the leadership of a nurse had a meaningful impact on the diabetes self-management skills and clinical findings of the patients. Practice Implications: It was determined that the average diabetes self-management education scores increased significantly when comparing before and after the self-management provided to patients and that the body mass index, preprandial blood glucose, and glycolyzed hemoglobin levels decreased at a statistically meaningful level.","PeriodicalId":15627,"journal":{"name":"Journal of Diabetology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136116406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical potential of glucagon-like peptide-1 analogs in the management of diabesity 胰高血糖素样肽-1类似物在糖尿病治疗中的临床潜力

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_102_22

Nidhi Sharma, Shreya Singh

{"title":"Clinical potential of glucagon-like peptide-1 analogs in the management of diabesity","authors":"Nidhi Sharma, Shreya Singh","doi":"10.4103/jod.jod_102_22","DOIUrl":"https://doi.org/10.4103/jod.jod_102_22","url":null,"abstract":"Obesity and cardiovascular complications are the two pandemic which plays a crucial role in the pathophysiology of type 2 diabetes mellitus. Loss of weight and increased cardiovascular risk are becoming the hurdles for the diabetic population. The tremendous hike in the rate of obesity is one of the main reasons for the increased cases of diabetes mellitus and hence, obesity becomes a high-risk factor for diabetes. Glucagon-like peptide-1 (GLP-1) agonists were initially developed for the treatment of diabetes mellitus but was found to be effective not only for the glycemic control but also for the weight loss. Hence this review article aims to assess the clinical efficacy of GLP-1 agonists in the management of weight loss, and also discusses the detailed insights of FDA approved drugs used in weight management, and discuss the mechanisms by which GLP-1 agonist, used in weight loss therapy. It also discusses the role of dual co-agonist in the treatment of obesity. This literature survey has been done by searching term “GLP-1 agonist, diabetes, obesity, novel drug targets” in the PubMed, Scopus, Embase, and web of science databases. Then, the search is further narrowed by including the articles having recent updates only and then further it is narrowed by excluding the animal studies and including only the clinical studies. This article is purely based on the published clinical data obtained from various clinical trials. Based on the previous studies and clinical trials, it has been observed that GLP-1 agonists such as liraglutide and semaglutide are more efficacious drug than other approved drugs in weight management therapy and have advantage of improving the blood glucose profile and reduces the cardiovascular risk also. It is also found that dual gastric inhibitory polypeptide (GIP)/GLP-1 agonists is regarded as the more effective in treating obesity than the GLP-1 agonist alone.","PeriodicalId":15627,"journal":{"name":"Journal of Diabetology","volume":"48 1","pages":"1 - 13"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73528442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceptions and behavioral patterns of Asian Indian adolescents diagnosed with type 1 diabetes 诊断为1型糖尿病的亚洲印度青少年的认知和行为模式

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_5_23

Velu Manya, A. Amutha, P. Latha, R. Unnikrishnan, Viswanathan Mohan, R. Anjana

引用次数: 0

Vitamin D and pathophysiology of polycystic ovary syndrome: A case–control study 维生素D与多囊卵巢综合征病理生理:一项病例对照研究

Journal of Diabetology Pub Date : 2023-01-01 DOI: 10.4103/jod.jod_122_22

Barnali Ray Basu, Sanchari Chakraborty, Ankita Samaddar, Randrita Pal, S. Saha, Nilansu Das

引用次数: 0