Journal of dental health, oral disorders & therapy最新文献

{"title":"Team-based learning student assessment instrument in Brazilian dental education: a validation study","authors":"F. B. Souza, Elaine Judite de Amorim Carvalho, Bruna de Castro, Emmanoel Matheus de Oliveira Matos, Ingrid Melo Schüler Arreguy","doi":"10.15406/jdhodt.2019.10.00481","DOIUrl":"https://doi.org/10.15406/jdhodt.2019.10.00481","url":null,"abstract":"","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"139 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74674549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hegab TMJ Splint (HTS)","authors":"A. Hegab","doi":"10.15406/jdhodt.2019.10.00480","DOIUrl":"https://doi.org/10.15406/jdhodt.2019.10.00480","url":null,"abstract":"Successful treatment of the TMJ internal derangement is based on understanding the biomechanical performance of the TMJ and subsequently to understand the biomechanical changes within the TMJ resulted from the occlusal splint to achieve harmonious relationships among teeth, joints, and muscles. As the disc displaced anteriorly, the elevator muscles continue to seat the condyle in the fossa resulting in decreasing the joint space and posterior-superiorly movement of the condyle. The aim of the splint is to move the condyle downward and foreword besides movement of the disk toward the normal position. These movements resulting in increasing the joint space, decreasing the joint pressure especially on the posterior attachment of the articular disk. Moreover; the vertical thickness of the occlusal splint return the normal physiologic function of the masticatory mechanism by relax the masticatory muscles by decreasing the electrical muscle activity and re-establish the disk condyle relationship (disc re-capture).4","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"25 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83574871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of two orthodontic NiTi wires regarding their structures and phase transformation temperatures","authors":"A. C. A. D. Souza, L. N. Souza, A. Drummond, V. Buono","doi":"10.15406/JDHODT.2019.10.00468","DOIUrl":"https://doi.org/10.15406/JDHODT.2019.10.00468","url":null,"abstract":"","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74418414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Car T-Cell Therapy in Head and Neck Cancers- A Meta-Analysis","authors":"","doi":"10.33140/jodh.03.02.1","DOIUrl":"https://doi.org/10.33140/jodh.03.02.1","url":null,"abstract":"Background: Cancer, defined by the World Health Organization (WHO) is “a large group of diseases characterized by the growth of abnormal cells beyond their usual boundaries that can then invade adjoining parts of the body and/or spread to other organs”. From extensive surgical excisions, radiotherapy, laser therapy to immunotherapies, various treatment strategies have been proposed and implemented so far but unfortunately none could improve the five year survival rate of the patients globally. Immunotherapy, being one amongst them, is a type of cancer treatment that boosts the body’s natural defenses to fight against cancer. The current concept of immunotherapy involves Chimeric antigen receptor or the CAR T-Cell therapy which involves alterations and modifications of T cells to fight cancer cells better. Until recently, the use of CAR T-cell therapy has been restricted to small clinical trials, largely in patients with advanced blood cancers and has also shown a promising window of hope in head and neck (especially oral) cancers as well. But these treatments have nevertheless captured the attention of the people because of the remarkable responses they have produced in some patients for whom all other treatments had stopped working. The current concept of immunotherapy involves the cancer vaccines making use of CAR T-cells which are the most powerful antigen presenting cells for the induction of antigen specific T cell response. This evidence based study therefore aims to highlight the clinical perspective of CAR T-Cell based immunotherapy in oral and other head and neck cancers. Aim: Assessment of efficacy of Car T-Cell Therapy in head and neck Malignancies. Research Question: Is Car T-Cell Therapy actually effective in treating head and neck cancers? Materials and Methods: Study sample included review of 70 research articles, based on scientific data bases from the English literature based COCHRANE collaboration having a definite RCT (Randomized Control Trial). The literature was studied, analyzed and assessed; comparison was made on their p (probability) values between various techniques in terms of their sensitivity and specificity. The articles were scrutinised based on the criterion for meta-analysis and finally 11 study articles were chosen for the study. Result and Conclusion: Due to its unique individual characteristics, it helps combat against the cancer cells at its very inception. Promises a complete and permanent cure for malignancies at the grass root level. It has a sensitivity and specificity of greater than 80-90% and enhances recovery rate from 40-50% to more than 90%. So on a bulls eye view, we can say that as the already existing techniques of oral cancer treatment are very superficial and not very significant, Car T-Cell therapy tends to bring about a paradigm shift in oral cancer treatment thereby giving a new ray of hope to cancer ailing patients.","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74333888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indirect versus direct pulp capping: reactionary versus reparative dentin","authors":"M. Goldberg","doi":"10.15406/jdhodt.2019.10.00466","DOIUrl":"https://doi.org/10.15406/jdhodt.2019.10.00466","url":null,"abstract":"They colonize and enlarge the dentino-enamel junction, widening the gap between the carious enamel and the soft carious dentin. Debris such as cell walls remnants remaining after by vegetal chewing, and fibers issued from muscle-like ‘meat’ may also be present. The soft carious dentin located beneath this zone of food debris is a mixture of bacteria and demineralized dentin that may be removed without drilling, using only manually sharp excavators. At the surface of this layer, the carious dentin is fully demineralized. The soft carious dentin displays enlarged tubules, containing bacteria acting within these reservoirs. This layer is totally deprived of peritubular dentin. From the surface to the depth of the lesion, the dentin progressively is less demineralized. Apatitic crystals provide some consistency to this layer. Gradually peritubular dentin reappears. The next carious layer includes a mixture of infected tubules filled by cariogenic bacteria and bacteria-free tubules. A continuous ring of peritubular dentin surrounds the lumens of the canaliculi. Intertubular dentin gradually reach the original structure. Demineralization and reprecipitation occurs at the surface of apatitic crystals, increasing their size in three directions. In the sound dentin, crystals display the following main dimensions: 34Å thick, 139Å wide and 250Å long. In the carious dentin, the crystals increase in thickness, and enlarge. Measurements indicate a 90Å (65-70Å) thickness x 300Å in width, and a length of x 500Å. Crystals reach a final diameter of 120-135Å according to Takuma et al.1","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73552175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lip Repositioning: A Secret to Magnificent Smile","authors":"Saurabh Anand Thawrani, Komal S Thawrani","doi":"10.33140/jodh.03.01.4","DOIUrl":"https://doi.org/10.33140/jodh.03.01.4","url":null,"abstract":"Aesthetics now a day became a demand for a fast growing\u0000population. Aesthetic dentistry provides fantastic solutions most\u0000of the times to enhance the way the people look, which in turn\u0000enhance self-confidence. A smile conveys a friendly nature, and\u0000reflects happiness and confidence. A smile is an important non-verbal\u0000method of communication and is an interaction between the teeth,\u0000the lip framework, and the gingival scaffold [1]. In the western\u0000world, a medium smile line with minimal gingival display (GD) is\u0000considered to be the most pleasing. When an excessive amount of\u0000gingiva is visible while smiling, this condition is commonly referred\u0000to as a ‘‘gummy smile’’ and it is found frequently in the general\u0000population. In a sample of over 450 adults, aged 20 to 30 years, 7%\u0000of men and 14% of women were found to have a gummy smile [2].\u0000Excessive gingival display is associated with different etiologies,\u0000which must be identified before treatment. It is imperative, therefore,\u0000for the clinician to evaluate the essentials of the patient’s smile, and\u0000consider the dynamic relationship between the patient’s dentition,\u0000gingiva, and lips while smiling [1,3].","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84812383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laser therapy on dental emergencies of patients with hemophilia as an alternative for hemostasis and reducing the use of factor VIII concentrate","authors":"Laura Beatriz Isidro Olán, Marco Antonio Rueda Ventura, C. A. Nájera, Armando Najera Castro","doi":"10.15406/jdhodt.2019.10.00464","DOIUrl":"https://doi.org/10.15406/jdhodt.2019.10.00464","url":null,"abstract":"Al (Gallium and aluminum arsenide); He, Ne (hHelium, neon). High intensity laser machines produce visible and physical effects in oral tissues and can be a substitute for cold scalpel or for conventional high rotatory instrument. Er:YAG (Erbium:Ytrium-Aluminum-Garnet) Laser has bactericidal effects against periodontal pathogenic bacteria and also eliminate bacterial endotoxins. Different tissue effects according to the temperature reached in a laser machine are showed in Table 1. In these cases series the temperature oscilated between 70-90 Celsius degrees to achieve hemostasis in different types of emergency oral bleeding. Table 1 Tissue effects according to the temparature reached","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76190606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The healthy root pulp, degradation and regeneration","authors":"M. Goldberg","doi":"10.15406/jdhodt.2019.10.00462","DOIUrl":"https://doi.org/10.15406/jdhodt.2019.10.00462","url":null,"abstract":"2. In the root, the Hopewell-Smith and Tomes granular layers constitute the outer limits (each of these layers being 8-15μm thick, with a total thickness approximately of 30μm). Both layers are located beneath the dentino-enamel or the dentinocementum junctions. In the outer mantle dentin, they contain a few tubules that are bent, and display minute diameter. In the granular layer, the peripheral layers include unfilled interglobular spaces (or calcospheritic structures), apparently empty but actually containing GAGs. These outer layers constitute the limits of the sound circumpulpal dentin (primary and secondary dentins). The pulp volume displays variable thickness, depending the age of the tooth.1","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84674705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LSTR 3mix-MP Important Efficacy Particularly Antibacterial and Periapical Lesions\u0000during Conservative Treatment in the Dentistry like RCT and Others Endodontics\u0000Management: Case Studies","authors":"","doi":"10.33140/jodh.03.01.3","DOIUrl":"https://doi.org/10.33140/jodh.03.01.3","url":null,"abstract":"Local sterilization and tissue repair which generally termed as LSTR, brings a radicular change in the field of conservative\u0000dentistry. Efficacy against antibacterial environment and non-surgical healing of periapical lesions much better than\u0000calcium hydroxide. LSTR 3Mix-MP, Using an antibacterial drug combination, therapy is a novel caries, pulpal treatment\u0000of primary tooth and root canal treatment. LSTR 3Mix-MP aims to eliminate causative bacteria from lesions and after\u0000sterilization, the host’s natural tissue recovery process usually the lesions are repaired or resolved. LSTR 3Mix MP where\u0000TAP (triple antibiotics paste) such as: Metronidazole, Ciprofloxacin, Minocycline and Vehicle MP Macrogol/polyethylene\u0000glycol and propylene glycol used to prepare. TAP has great antibacterial efficacy particularly against enterococci which\u0000remains after successful root canal treatment, effective eradication of the causative microorganisms during root canal\u0000treatment procedures. Residual infection in Root canal therapy has always been an area of interdermind or vague for\u0000a treating dental surgeon. Lesion sterilization and tissue repair (LSTR) therapy is a non-surgical or non-conventional\u0000endodontic treatment procedure that involves non-instrumentation or minimal instrumentation followed by placement of\u0000a triple antibiotic paste in a medication along with Macrogol and Propylene glycol.","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"236 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83951162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observers Agreement in Perception of Non-Cavitated Approximal Dental Caries\u0000by Intraoral Digital CCD Radiography at Different Exposure Parameters and\u0000Corresponding Required Radiation Dose","authors":"Mohamed Mehanny, Marcel Noujeim","doi":"10.33140/jodh.03.01.1","DOIUrl":"https://doi.org/10.33140/jodh.03.01.1","url":null,"abstract":"Objectives: To evaluate the diagnostic accuracy of Charged Coupled device (CCD) in detection of Non- Cavitated Approximal\u0000caries at different exposure parameters in relation to radiation dose in vitro.\u0000Study Design: Seventy-eight surfaces of extracted teeth were inserted in acid gel to create non-cavitated proximal caries\u0000with different depth, and then Radiographs have been taken to all teeth by CCD sensor. Radiographs were interpreted by\u0000three observers. The lesions were classified as (N) No lesion, (D1) Less than ½ enamel thickness, (D2) more than halfway of\u0000enamel but not involve DEJ. (D3) Dentin caries. Teeth were randomly selected for histological analysis after consensus from\u0000three oral and maxillofacial radiologists as Gold standard. The corresponding radiation dose was measured by unfors meter\u0000device at different exposure parameters.\u0000Results: The histological examination showed that the distribution of lesions was 39.8% Sound, both enamel lesions are\u0000equal 17.8%, Dentin lesions 24.6.\u0000The sensitivity and specificity of CCD to detect normal surfaces were 0.95, D1 was 0.37, D2 was 0.74 and D3 was 0.86. As\u0000the lesions depth increased, the sensitivity increased.\u0000The higher image quality was produced by using exposure parameters (70 KvP, 160 ms) and (70 KvP, 200 ms). While, (60\u0000KvP, 200 ms) and (60 KvP, 250 ms) produced the worse image quality.\u0000Conclusion: Regard the balance between the higher diagnostic accuracy of digital images and minimum radiation dose:\u0000using exposure parameters as (70 KvP, 160 ms) is considered the best image quality and relative dose (81 mSv). While, (70\u0000KvP, 125ms) and (66 KvP, 160 ms) are little bit lower quality and corresponding dose are (63), (73) respectively. Although\u0000(70 KvP, 200 ET) produce higher image quality but its relative dose is high (101mSv).","PeriodicalId":15598,"journal":{"name":"Journal of dental health, oral disorders & therapy","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75881958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}