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CD1a-positive dendritic cell-enriched pigmented purpuric dermatosis in association with dyslipidemia cd1a阳性树突状细胞富集的色素性紫癜性皮肤病与血脂异常相关
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_85_20
T. Hinojosa, D. Lewis, M. Duvic, C. Torres‐Cabala
{"title":"CD1a-positive dendritic cell-enriched pigmented purpuric dermatosis in association with dyslipidemia","authors":"T. Hinojosa, D. Lewis, M. Duvic, C. Torres‐Cabala","doi":"10.4103/jdds.jdds_85_20","DOIUrl":"https://doi.org/10.4103/jdds.jdds_85_20","url":null,"abstract":"Indeterminate cells (ICs) are dendritic cells (DCs) that share the histologic features of Langerhans cells and macrophages but lack Birbeck granules. It remains unclear whether IC histiocytosis is a separate disease entity or a reactive process. We report the case of a male with an 8-year history of dyslipidemia who developed extensive pigmented purpuric papules. Laboratory studies revealed peripheral monocytosis (8.2%), and two skin biopsies showed a dermal lichenoid lymphohistiocytic infiltrate composed of CD4+ T cells and CD8+ T cells and CD68+CD163+CD1a+Langerin histiocytes. PD-1/PD-L1+T cells were present in the dermis. Our case may help in understanding the pathogenesis of IC histiocytosis, and we hypothesize that expression of CD1a+ dermal DCs and T-cell dysfunction is a reactive process to dyslipidemia.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"12 1","pages":"89 - 91"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88571648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Autologous platelet-rich fibrin membrane as a wound dressing in the treatment of chronic nonhealing leg ulcers: A prospective study 自体富血小板纤维蛋白膜作为伤口敷料治疗慢性不愈合腿溃疡:一项前瞻性研究
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_80_20
Amina Asfiya, Sacchidanand Sarvajnamurthy, F. Shariff, Leelavathy Budamakuntala
{"title":"Autologous platelet-rich fibrin membrane as a wound dressing in the treatment of chronic nonhealing leg ulcers: A prospective study","authors":"Amina Asfiya, Sacchidanand Sarvajnamurthy, F. Shariff, Leelavathy Budamakuntala","doi":"10.4103/jdds.jdds_80_20","DOIUrl":"https://doi.org/10.4103/jdds.jdds_80_20","url":null,"abstract":"Background: Chronic nonhealing ulcers of the lower extremity are a cause of morbidity and mortality. The various treatment options available are limited and unsatisfactory. Promoting wound healing with an autologous platelet membrane could be a safe, easy, and inexpensive modality. Purpose: To assess an autologous platelet-rich fibrin (PRF) membrane as a wound dressing in the treatment of chronic nonhealing leg ulcers. Methods: A prospective study enrolled 30 patients with chronic nonhealing leg ulcers. Autologous PRF was applied weekly for 6 weeks. At each visit, the ulcer healing was assessed with wound measurements and photographs. The treatment outcome was defined as a percentage in a change of area and volume of the ulcer at the end of the study period. Results: Thirty patients with chronic nonhealing leg ulcers were treated for 6 weeks. 100% improvement in area of the ulcer was seen in 43% ulcers. The mean percentage of improvement in area of the ulcer was 72%. The mean percentage of improvement in volume of the ulcer was 77%. The mean duration of healing was 5 weeks. Conclusion: This study was limited by the lack of a control group. Autologous PRF may be useful for the treatment of chronic nonhealing leg ulcers which can be done on an outpatient basis with minimum adverse effects.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"67 1","pages":"73 - 76"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76978993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seborrheic keratosis-like changes in epidermal inclusion cyst: An unusual feature in a usual entity 表皮包涵囊肿的脂溢性角化样改变:在正常实体中不寻常的特征
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_110_21
S. Palo, C. Gargade
{"title":"Seborrheic keratosis-like changes in epidermal inclusion cyst: An unusual feature in a usual entity","authors":"S. Palo, C. Gargade","doi":"10.4103/jdds.jdds_110_21","DOIUrl":"https://doi.org/10.4103/jdds.jdds_110_21","url":null,"abstract":"A 58-year-old male presented with an asymptomatic, slowly growing, cystic and mobile swelling on the left leg calf of 6 months duration. Fine-needle aspiration cytology was suggestive of epidermal inclusion cyst. Histopathological examination revealed seborrheic keratosis-like changes in the cyst wall comprising of marked acanthosis, papillomatosis, pseudohorn cysts, squamous eddies, and clumps of keratohyalin granules. This is a very rare variant of epidermal inclusion cyst, possibly induced by infection with human papillomavirus.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"2 1","pages":"80 - 81"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73230945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linezolid-induced black hairy tongue: A case report and review of literature 利奈唑胺致黑毛舌1例报告及文献复习
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_1_22
M. Siddiqui, M. Adil, S. Amin, Kritika Xess
{"title":"Linezolid-induced black hairy tongue: A case report and review of literature","authors":"M. Siddiqui, M. Adil, S. Amin, Kritika Xess","doi":"10.4103/jdds.jdds_1_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_1_22","url":null,"abstract":"Black hairy tongue is an asymptomatic and benign condition presenting with black-to-brownish discoloration of the dorsum of the tongue with elongated filiform papillae. Several medications, particularly antibiotics, are implicated in its causation. Xerostomia, abnormal desquamation of the tongue, use of oxidizing mouthwashes, excessive intake of nicotine, coffee, and tea, and immunosuppressive states predispose to the development of this condition. Herein, we describe a case of a young female who developed black hairy tongue within 5 days of linezolid intake. The discoloration disappeared after 7 days of stopping the drug. We also summarize the various reports of black hairy tongue due to linezolid in a tabular form. We aim to highlight the importance of medication history in the identification of this uncommon condition. We also emphasize identifying risk factors for this condition and educating the patients about them.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"48 1","pages":"77 - 79"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75595631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allergens in corticosteroid vehicles in Saudi Arabia 沙特阿拉伯皮质类固醇车辆中的过敏原
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_26_22
M. Alharbi, S. Almutairi, Maisa A Alfalah
{"title":"Allergens in corticosteroid vehicles in Saudi Arabia","authors":"M. Alharbi, S. Almutairi, Maisa A Alfalah","doi":"10.4103/jdds.jdds_26_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_26_22","url":null,"abstract":"Background: Both the active steroid compounds and vehicle ingredients of the topical corticosteroid products can cause allergic contact dermatitis. Purpose: The objective of the current study was to assess the presence of allergens in topical corticosteroid vehicles used in Saudi Arabia. Methods: Package inserts of topical corticosteroid products available through February 2022 were reviewed independently by two dermatologists. Topical corticosteroids were excluded if they were not approved by the Saudi Food and Drug Authority. Results: Out of 79 products examined, 49 (62%) were included in the study. Out of the 49 products, 29 (59%) had one or more allergens (a total of 38 allergens). Three topical corticosteroids were responsible for more than 80% of all allergens. These included mometasone furoate (n = 12), clobetasol propionate (n = 7), and betamethasone valerate (n = 5). The most frequent allergens were propylene glycol (66%), parabens (16%), sorbitan (13%), and lanolin (5%). Formaldehyde(s), methylchloro-isothiazolinone, and methyl-isothiazolinone were not detected in any product. Approximately 48% of the products with allergens were creams, 41% were ointments, and 10% were lotions. With two exceptions, there were no statistically significant differences in the overall presence of allergens by the type, formulation, and concentration of topical corticosteroid products. Conclusion: Almost 60% of topical corticosteroid products widely used in dermatologic clinics in Saudi Arabia had one or more vehicle allergens. Since the best treatment for contact allergy is avoidance, dermatologists should be aware of vehicle allergens in topical corticosteroids and consider the use of allergen-free products.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"13 1","pages":"61 - 66"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87144748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Saudi adolescent present with new-onset vitiligo post-COVID-19 vaccination: Case report 沙特青少年在covid -19疫苗接种后出现新发白癜风:病例报告
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_35_22
Abdullah Alnaim, Amnah Al-Mulhim, Mohammed Al-Momen, Lenah Shaikh
{"title":"Saudi adolescent present with new-onset vitiligo post-COVID-19 vaccination: Case report","authors":"Abdullah Alnaim, Amnah Al-Mulhim, Mohammed Al-Momen, Lenah Shaikh","doi":"10.4103/jdds.jdds_35_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_35_22","url":null,"abstract":"Coronavirus disease of 2019 (COVID-19) is a relatively new pandemic; the first reported case was in late 2019, and the first vaccine was given in December 2020. To this date, multiple side effects have been reported with COVID-19 vaccines. Nonetheless, autoimmune (AI) diseases with the COVID-19 vaccine have rarely been associated. We described herein a case of sudden onset of vitiligo occurring after the first dose of the COVID-19 vaccine. To date, there are less than 10 reported cases of vitiligo post-COVID-19 vaccine. This report aims to recognize AI disease presentation with vaccines, specifically COVID-19.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"43 1","pages":"96 - 98"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90255503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Topical immunotherapy for alopecia areata: A successful diphenylcyclopropenone protocol 局部免疫治疗斑秃:一个成功的二苯环丙烯方案
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_21_22
Melika Motamedi, Kush Bapujib, N. Dhaliwal
{"title":"Topical immunotherapy for alopecia areata: A successful diphenylcyclopropenone protocol","authors":"Melika Motamedi, Kush Bapujib, N. Dhaliwal","doi":"10.4103/jdds.jdds_21_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_21_22","url":null,"abstract":"Alopecia areata (AA) is an autoimmune disorder that involves the destruction of anagenic hair follicles, resulting in non-scarring patchy hair loss. The patient presented in the following case had not seen improvement by use of conventional treatments and was started on topical immunotherapy, diphenylcyclopropenone (DPCP). This agent is commonly left as a last resort due to its constant need for follow-up, clinician-required administration, and risk of adverse effects. The following case presents a titration schedule using DPCP, resulting in minimal adverse effects and dramatic improvement in hair regeneration.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"150 1","pages":"92 - 95"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77393980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 3-year-old girl with old face appearance: Case report 3岁女童面容老旧1例报告
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_51_22
Hamad Ayed Alfahaad
{"title":"A 3-year-old girl with old face appearance: Case report","authors":"Hamad Ayed Alfahaad","doi":"10.4103/jdds.jdds_51_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_51_22","url":null,"abstract":"Hutchinson–Gilford Progeria Syndrome (HGPS) is a genetic disorder. Patients who suffer from this disorder show premature aging and a “plucked-bird” appearance on the face. This case reports a 3-year-old female, who manifested the symptoms of HGPS. The patient has a large head and eyes, receded jaws, a narrow nose, protruded forehead, decreased eyebrows and eyelash hair, stunted growth, and severe wrinkles. A genetic test was conducted to confirm the existence of the disease. The case is reported due to its rarity.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"65 1","pages":"99 - 101"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86135626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cavernous hemangioma resembling lymphangioma circumscriptum: The central role of dermoscope in diagnosis 海绵状血管瘤:皮肤镜在诊断中的核心作用
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_144_20
K. Djawad
{"title":"Cavernous hemangioma resembling lymphangioma circumscriptum: The central role of dermoscope in diagnosis","authors":"K. Djawad","doi":"10.4103/jdds.jdds_144_20","DOIUrl":"https://doi.org/10.4103/jdds.jdds_144_20","url":null,"abstract":"Vascular tumors and malformations are often called “angiomas.” Cavernous hemangiomas are more commonly found in adolescents, often on the face and rarely on the extremities. Surgery may be pursued for cosmesis in cases of cutaneous lesions that do not involute. A 12-year-old girl presented with a lump on her right knee 4 years ago. Initially, the lump was flat and appeared like a bluish bruise but then slowly enlarged. There were no complaints of itching, pain, and other discomfort. Physical examination showed a 3.2 cm × 2.1 cm mobile violaceous tumor composed of dark red or blue-black vesicles in the right knee, clinically resembling lymphangioma circumscriptum. Dermoscopic examination showed a pattern composed of central dark, red-blue lacunae, white structures, and a peripheral brownish homogeneous area, which was consistent for cavernous hemangioma. The patient underwent biopsy excision and the diagnosis was confirmed through histopathological examination.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"43 1","pages":"54 - 56"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86727082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical pearl: A small handy apparatus for chemical cautery 外科用珍珠:一种用于化学烧灼的小而方便的器具
Journal of Dermatology and Dermatologic Surgery Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_7_21
M. Mukhtar
{"title":"Surgical pearl: A small handy apparatus for chemical cautery","authors":"M. Mukhtar","doi":"10.4103/jdds.jdds_7_21","DOIUrl":"https://doi.org/10.4103/jdds.jdds_7_21","url":null,"abstract":"","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"201 2 1","pages":"43 - 44"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85614580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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