Journal of clinical & experimental dermatology research最新文献

{"title":"Acne-Related Conditions and Sensitive Skin Syndrome","authors":"C. Michael","doi":"10.35248/2155-9554.21.12.E117","DOIUrl":"https://doi.org/10.35248/2155-9554.21.12.E117","url":null,"abstract":"","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"117 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80564926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 and Impact on Dermatology","authors":"L. Martini","doi":"10.35248/2155-9554.21.12.E115","DOIUrl":"https://doi.org/10.35248/2155-9554.21.12.E115","url":null,"abstract":"","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"11 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88774379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Analysis of a Single- Kuwaiti Center Clinical Experience Toward Development of Proper Controlling Treatment of 84 Pemphigus Patients with a Long-Term Follow-Up: Efficacy and Safety of the Multidrug Protocol Combining Intravenous Immunoglobulin with the Cytotoxic Immunosuppressor Drugs","authors":"I. Almasry, V. Lazarević, F. Alkhawaja, Jihan M Rajy, N. Musami, Nadia Alnaki, R. Dvořák, Aliaa Sadek, Humoud Al Sabah, Atlal Al-Lafi","doi":"10.35248/2155-9554.21.12.567","DOIUrl":"https://doi.org/10.35248/2155-9554.21.12.567","url":null,"abstract":"Pemphigus is the name of a group of autoimmune pathological entities characterized by the formation of intraepithelial blisters in the skin and/or mucosa. Pemphigus vulgaris (PV) and Pemphigus foliaceus (PF) are considered as classical forms. Rare, non-classical forms of Pemphigus include: Pemphigus herpetiformis, IgA pemphigus, Paraneoplastic pemphigus, IgG/IgA pemphigus. Aim: Aim of our study is to explore the prognostic influence of clinical, immunological and therapeutic drugs on disease course and remission in different pemphigus variants in Kuwait and to establish a safe and effective multidrug protocol. Plan of the study is to make a correlation between epidemiological factors, therapy used and clinical and immunological remission, as well as, follow up of comorbidities in our patients. 84 patients were evaluated, from 1st January 1990 to 31st December 2013. IVIG is used as a third-line adjuvant treatment initially flanked by high-dose systemic corticosteroids and steroid- sparing immune-suppressants. Thus, this multidrug IVIG regimen made it possible to achieve a rapid control of the pemphigus symptoms, with progression to a stable disease remission, while maintenance an overall safety of treatment.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"23 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81071238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Impact of Alopecia Areata on Egyptian Patients","authors":"Doaa A. E. Abou-Taleb, Omnia H Abd El Hameed, Alaa Ea Moubasher","doi":"10.35248/2155-9554.21.12.568","DOIUrl":"https://doi.org/10.35248/2155-9554.21.12.568","url":null,"abstract":"Alopecia occupies an important place in psychiatric comorbidity and may be associated with anxiety, stress and depression. Psychiatric problems are more common in patients with alopecia than in healthy individuals. This study aimed to assess the psychological impact of Alopecia Areata (AA) among Egyptian patients by using the Arabic version of the Depression, Anxiety and Stress Scale (DASS-42). Patients and methods: A total of 100 Egyptian patients with AA were randomly recruited from the outpatient clinics of the department of dermatology of Assiut University Hospital (AUH). The SALT score used to assess the severity of AA. Patients were asked to describe the impact of AA on their life by filling in the Arabic version of DASS-42. Results: 71% of the AA patients were males and 29% were females, 93% were educated either higher education 46% or lower education 47%. The patients of AA who had depression were 90 patients (26% with extreme depression, 22% with severe depression, 29% with moderate depression and 13% with mild depression). Also, anxiety was present in 85% of patients (38% with extreme anxiety, 24% with severe anxiety, 18% with moderate anxiety and 5% with mild anxiety). Regarding stress, it was present in 95% of patients (35% with extreme stress, 23% with severe stress, 32% with moderate stress and 5% with mild stress). Conclusion: Our study may serve as a stimulus to dermatologists to improve the relationships with their patients and re-evaluate their management of AA and put in consideration the psychological management that can help to improve the clinical outcomes in Egyptian patients with AA.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"16 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78404388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Recovery of Skin Cancer Services Following the COVID-19 Pandemic, Using Combined Speciality Clinics to Decrease Waiting Times and Improve Cost Efficiency","authors":"C. Brennan, M. Stone, R. Pinder, A. Gowda","doi":"10.46889/jdr.2021.2304","DOIUrl":"https://doi.org/10.46889/jdr.2021.2304","url":null,"abstract":"The unprecedented COVID-19 pandemic continues to have significant ramifications for nonurgent medical treatment and cancer care globally. Provision of healthcare for noncommunicable disease has been dramatically curtailed across the world, in order to redirect resources in a bid to gain control of the coronavirus. There are multiple reports internationally of significant reductions in urgent cancer referrals [1-4]. In England, patients diagnosed with a stage I primary fell for all types of cancer in the first 4 months of the pandemic compared to pre-pandemic levels (March to June 2019 vs 2020; 18400 vs 12400), equating to a drop of approximately 1500 people per month [5]. Skin cancer primaries are amongst the most impacted1, as by September 2020 the estimated number of malignant cancer diagnoses had reached 95% of pre-pandemic activity in all groups except non-melanoma skin cancer [5]. A Canadian study examined the pandemic’s influence on skin biopsies and demonstrated a precipitous drop to just 15% of expected biopsy numbers compared to the same period in the year prior to the pandemic [4]. Furthermore, the elderly, females and patients living in areas of greater socioeconomic deprivation were disproportionately affected and less likely to attend for skin biopsies when suspicion of cutaneous malignancy was present [4]. Whilst substantial improvements in biopsy rates have been noted, it is expected that a large backlog of cases will","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"143 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73533168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Pseudochromohidrosis Cured with Oral Erythromycin and Topical Clindamycin","authors":"Rashmi Singh","doi":"10.46889/jdr.2021.2205","DOIUrl":"https://doi.org/10.46889/jdr.2021.2205","url":null,"abstract":"Apocrine chromohidrosis and eccrine pseudochromohidrosis are both rare skin presentations. In case of former patient presents with coloured sweats in apocrine distributions usually axilla, breast etc., while later presents with coloured sweat in eccrine distribution. Such cases need to be reported after other possibilities with similar presentations have been ruled, and need special mention in literature as mostly they are misdiagnosed as factitious. Hereby, I am also reporting one such case of pseudochromohidrosis which needed attention as it was causing anxiety to both patient and family members and its proper diagnosis and treatment brought a great relief to them.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85380023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of COVID-19 on Outcomes in Aesthetic Medicine: AMulticentre Retrospective Study of Italian Patients","authors":"Maurizio Cavalllini, P. Cirillo, S. Fundarò, G. Muti, A. Santorelli, G. Salti","doi":"10.35248/2155-9554.21.12.553","DOIUrl":"https://doi.org/10.35248/2155-9554.21.12.553","url":null,"abstract":"COVID-19 has profoundly affected the delivery of aesthetic treatment to the general public. In our cohort of patients who underwent botulinum toxin, soft tissue filler infiltration, and thread lifting using bioabsorbable suspension threads from January to April 2020, there was no observed increase in the number of complications. Although cutaneous complications were seen in some botulinum toxin and soft tissue filler injection recipients, the observed complication rates were similar to pre-pandemic figures. Also, these were relatively mild and were easily reversible with supportive therapy. Patients who underwent suspension thread placement did not have apparent complications regardless of having had systemic symptoms attributable to COVID-19. Regardless of the rapid upsurge of the number of cases from February to March, the reported incidences of cutaneous manifestations of possible complications remained low.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"95 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84906041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cosmetic Dermatology Training Exposure among Saudi Residents: A Cross Sectional Study","authors":"Mohammed H. Abduljabbar","doi":"10.35248/2155-9554.21.S8.548","DOIUrl":"https://doi.org/10.35248/2155-9554.21.S8.548","url":null,"abstract":"Background: For more than half a century, cosmetic dermatology has been an integral part of dermatology practice. Dermatologists perform more cosmetic procedures than any other specialty on the basis of data from the Center for Medicare and Medicaid Services. Therefore; it is essential that young dermatologists be educated about cosmetic procedures and achieve competency and proficiency in this area, to provide competent care. Aim of the study: This study aimed to assess the current state of cosmetic dermatology training in residency programs. Objectives: To assess the educational exposure of dermatology residents to cosmetic dermatology, to elicit their perceptions on the effect of various teaching strategies for developing procedural skills during their residency in SCFHS-accredited programs in Saudi Arabia, focusing on the residents experience and perspective. Methods: An analytic cross-sectional study was performed on Saudi Dermatology residents in Saudi Arabia at 2019. Permission was taken from Champlain et al. to use the questionnaire. An anonymous self-administrated questionnaire was used which included two parts: the first part inquired about demographic information and the second part inquired about cosmetic dermatology training during residency. Data were analyzed using the Statistical Package for Social Sciences version 20. Results: Thirty six dermatology residents participated in this study with mean age (27.6 ± 1.9), 61.1% were female, 33.3% were in the 4th year and 22.2% were in the first year. Nearly 55.5% of the participants, their residency program were with more than 15 residents. 86% of them had formal lectures including laser, filler, sclerotherapy and chemical peels while 63% were only observer during different cosmetic procedures. Residents in the cosmetic dermatology program prefer more hands-on training (61%) versus lectures (25%) or assigned readings (11%). Conclusion: The residency training program in Saudi Arabia like many programs that provide hands-on cosmetic dermatologic training but there is still lack in the level of participation as a primary surgeon which needs more facilities in both devices and procedures.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"49 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75989819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulatory Role Played by the mRNA Binding Protein Tristetraprolin in the Skin and its Involvement in Different Diseases","authors":"R. Lotti, T. Zanocco-Marani","doi":"10.35248/2155-9554.21.S10.574","DOIUrl":"https://doi.org/10.35248/2155-9554.21.S10.574","url":null,"abstract":"The mRNA binding protein Tristetraprolin (TTP), encoded by the ZFP36 gene, plays a fundamental regulatory role in a wide variety of cellular processes by means of its widespread expression in different tissues, and of its ability to post transcriptionally regulate the stability, and therefore the expression, of multiple specific target mRNAs. Because of these features, TTP expression and activity are strictly regulated, and malfunctions of such mechanisms underlie different pathologies. Here we recapitulate the role of TTP in the skin, and its involvement in different conditions, with special reference to psoriasis and cancer.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"1 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79972373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reharmonize: Aesthetic Modalities Founded on the Concepts of Restoring, Reshaping, and Resurfacing for the Comprehensive Treatment of Millennials","authors":"V. Wong, Dennis Malvin Hern, ez Malgapo","doi":"10.35248/2155-9554.21.12.562","DOIUrl":"https://doi.org/10.35248/2155-9554.21.12.562","url":null,"abstract":"Background: Non-surgical minimally invasive procedures, typically in combination, are now becoming the norm. The integrated use of these modalities can be offered to millennial patients, who have unique demands and aesthetic goals. Objective: We aimed to demonstrate the effects of Definisse™ Fillers, Definisse™ Threads and Definisse™ Peel Program in combination to treat two millennials, one female and one male. Case description: The male subject had noticeable change in his facial proportions with correction of hollows over the malar and suborbital areas and a more prominent chin with the help of both Definisse™ Fillers and Definisse™ Threads (double needle and free floating). There was also noticeable improvement in the pigmentation with a more even and clearer skin tone after Definisse™ Lightening Peel application. The patient verbalized a high level of satisfaction with the effects of the treatment overall. The female subject had a noticeable correction of the prominence on her nasal bridge. There was a slightly pronounced lateral and upward lifting of the cheeks. Her uneven pigmentation was also seen to diminish following Definisse™ Peel Program. She was likewise very satisfied and happy with the result of her treatment. Conclusion: The prejuvenation effect of a combination of minimal invasive procedures provides an optimal aesthetic option for millennials. The results obtained confirm the importance of the reharmonize approach to male and female aesthetics. And this is accomplished by working from deep to superficial facial, with satisfactory and long-lasting aesthetic outcomes.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"45 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86508813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}