Journal of Clinical Dermatology最新文献_第2页

Serum Trace Element Levels in Patients with Alopecia Areata 斑秃患者血清微量元素水平

Journal of Clinical Dermatology Pub Date : 2020-07-01 DOI: 10.19070/2332-2977-2000057

N. Sherif

引用次数: 0

Estimation of Serum Trace Elements Levels in Libyan Patients with Psoriasis Vulgaris: A Case Control Study 利比亚寻常型银屑病患者血清微量元素水平的估计:一项病例对照研究

Journal of Clinical Dermatology Pub Date : 2020-06-10 DOI: 10.11648/J.IJCD.20200301.14

N. Sherif, S. El-Dibany

{"title":"Estimation of Serum Trace Elements Levels in Libyan Patients with Psoriasis Vulgaris: A Case Control Study","authors":"N. Sherif, S. El-Dibany","doi":"10.11648/J.IJCD.20200301.14","DOIUrl":"https://doi.org/10.11648/J.IJCD.20200301.14","url":null,"abstract":"Background: Psoriasis is a chronic autoimmune skin disease with a worldwide prevalence of 2–3%. Psoriasis is caused by a complex interplay among the immune system, genetic background, auto-antigens, and environmental factors. Trace elements are required for the normal functioning of many enzymes and play a significant role in the development of many diseases. Objective: To assess the serum levels of zinc, copper, magnesium, iron and folate in patients with psoriasis compared to healthy controls. Patients and Methods: A total of 41 patients with psoriasis vulgaris were compared with 50 age and sex matched healthy subjects. Serum levels of zinc (Zn), copper (Cu), magnesium (Mg), iron (Fe) and folate were measured in both groups and compared. Psoriasis Area and Severity Index (PASI) were used to measure the severity of the disease. Results: The mean serum level of Zn was 142.2±52 in patients compared to 90.2±18.9 in the controls (P=.000), serum level of Cu was 161.1±58.5 in patients versus 156.3±42.8 in control group (P=.650). Serum Mg was 2.4±0.5 in patients and 1.9±0.2 in control subjects (P=.000). Serum Fe was 90.8±50 in patients as compared to 116.9±32.4 in control subjects (P=.004), whereas, serum folate was 6.6±3.9 in patients and 9.5±5.3 in control subjects (P=.005). There was no significant direct correlation between levels of trace elements under study and PASI scoring. Conclusions: Trace elements particularly Zn, Cu, and Mg appear to be elevated in psoriasis patients, while Fe and folate were low in psoriatic patients, however, they can't serve as biomarkers for disease activity.","PeriodicalId":15418,"journal":{"name":"Journal of Clinical Dermatology","volume":"26 1","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2020-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78989496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety, Tolerability and Cost Effectiveness of Commercially Available vs. Freshly Prepared Salicylic Scid Peel in Treatment of Acne: An Indian Perspective 市售水杨酸皮与新鲜制备水杨酸皮治疗痤疮的安全性、耐受性和成本效益:印度观点

Journal of Clinical Dermatology Pub Date : 2020-02-13 DOI: 10.19070/2332-2977-2000055

I. Pandya, P. Pandya

引用次数: 0

Determinants of Syphilis Infection among Women Seeking Antenatal Care and Delivery Services in Olenchity Primary Hospital: A Case-Control Study 在奥伦蒂市初级医院寻求产前保健和分娩服务的妇女中梅毒感染的决定因素:一项病例对照研究

Journal of Clinical Dermatology Pub Date : 2020-02-04 DOI: 10.11648/J.IJCD.20200301.13

Gindo Lema Gutema, S. G. Abeya, G. Ayele

{"title":"Determinants of Syphilis Infection among Women Seeking Antenatal Care and Delivery Services in Olenchity Primary Hospital: A Case-Control Study","authors":"Gindo Lema Gutema, S. G. Abeya, G. Ayele","doi":"10.11648/J.IJCD.20200301.13","DOIUrl":"https://doi.org/10.11648/J.IJCD.20200301.13","url":null,"abstract":"The magnitude of syphilis infection among pregnant women is increasing worldwide. Syphilis infection during pregnancy is a risk of congenital syphilis for the fetus, might result in intrauterine death. The objective this study was to identify the predictors of syphilis infection among pregnant and delivering mother in Olenchity primary hospital from October 2017 to January 2018 G. C. Unmatched case-control study design (61 cases and 244 controls) was conducted among women seeking Antenatal care and delivery services. Cases and controls were selected based according to their of the serology result. Data was collected using pre-tested and structured questionnaire. The collected data were entered into EPI-info version 7 and analyzed using SPSS version 20. Principally binary logistic regression model was used to estimate the odds ratio at 95% confidence intervals. Education (AOR, 0.381; 95% CI: 0.169, 0.857), knowledge about Sexually transmitted Infections (AOR, 0.244 95% CI: 0.114, 0.522), loss of baby during pregnancy (AOR, 2.275; 95% CI: 1.022, 5.065), multiple sexual partner (AOR, 3.071; 95% CI: 1.220, 7.730), Cigarette smoking (AOR 7.628; 95% CI: 1.714,33.946), Human immune deficiency virus Positives (AOR, 41.145; 95% CI: 2.250, 752.362) were factors significantly associated with syphilis. Factors like having primary and secondary education and knowledgeable about sexually transmitted infections were less likely to have syphilis. However, having the history of multiple sexual partner, cigarette smoking, lose baby during pregnancy, HIV positive were more likely to associate with syphilis infection. These factors should be taken into consideration to prevent or curb the problems syphilis infection.","PeriodicalId":15418,"journal":{"name":"Journal of Clinical Dermatology","volume":"15 1","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2020-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88014746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine Learning Algorithm Applied for Predicting the Presence of Mycobacterium Tuberculosis 机器学习算法用于预测结核分枝杆菌的存在

Journal of Clinical Dermatology Pub Date : 2020-01-10 DOI: 10.11648/J.IJCD.20200301.12

Ibrahim Goni

{"title":"Machine Learning Algorithm Applied for Predicting the Presence of Mycobacterium Tuberculosis","authors":"Ibrahim Goni","doi":"10.11648/J.IJCD.20200301.12","DOIUrl":"https://doi.org/10.11648/J.IJCD.20200301.12","url":null,"abstract":"Tuberculosis is a contagious disease that causes of death. The body's response to active TB infection produces inflammation that can damage the lungs. Areas affected by active TB gradually fill with scar tissue. It is spread from person-to-person. A person is often infected by inhaling the germs. Tuberculosis germs are spread into the air when a person with TB disease of the lungs or throat coughs, sneezes, speaks, or sings. These germs can stay in the air for several hours, depending on the environment. However, patients with chronic diseases, such as diabetes, chronic kidney disease, and silicosis, are at elevated risk. Finally, age younger than 4 years, long-term malnutrition, and substance abuse are independent risk factors for disease. The aim of this research work is to develop an adaptive Neuro-Fuzzy system for predicting the presence of Mycobacterium tuberculosis. The system is structured with inputs and one output of which rules were generated by the system with the help of three domain Medical expertise and are injected in to the knowledge based where the system would use this rules to make decisions and draw a conclusion. MATLAB7.0 was used to implement this experiment using fuzzy logic and Neural Network toolbox. In this experiment linguistic variables are evaluated using Gaussian membership function.","PeriodicalId":15418,"journal":{"name":"Journal of Clinical Dermatology","volume":"15 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89052140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Ankyloblepharon Filiforme Adnatum: A Case Report 腓肠肌强直体1例报告

Journal of Clinical Dermatology Pub Date : 2020-01-09 DOI: 10.11648/J.IJCD.20200301.11

N. Albab, S. belghmaidi, I. Hajji, A. Moutaouakil, I. Ouahidi, M. Bourrous

{"title":"Ankyloblepharon Filiforme Adnatum: A Case Report","authors":"N. Albab, S. belghmaidi, I. Hajji, A. Moutaouakil, I. Ouahidi, M. Bourrous","doi":"10.11648/J.IJCD.20200301.11","DOIUrl":"https://doi.org/10.11648/J.IJCD.20200301.11","url":null,"abstract":"Introduction: Ankyloblepharon filiform adnatum (AFA) is defined by partial or complete fusion of the eyelids by webs of skin. It can be interest a part of the eyelid or its totality. Diagnosis should be done at an early stage of life. It is basically surgical. Case information: We describe a male new born at his twentieth day of life was referred for assessment of his both right and left eyelids. His was born on term. Pregnancy and delivery went normally. However there were first degree consanguinity. The baby was healthy apart from multiples bands of tissue between upper and lower eyelids of both of his eyes. These bands were axial, covering the pupil, and prevented full opening of both eyelids. The baby underwent surgery consisting of excising the bands of tissue with scissors at the level of each eyelid margin. Eye examination did not reveal any abnormality. Two months later, the follow up showed no anomaly. Conclusion: Ankyloblepharon filiform adnatum may be rare but it is potentially amblyogenic. However, the major practical importance of this anomaly is, perhaps, to alert the physician as to the presence of other associated congenital anomalies and the treatment should be performed as soon as the diagnosis is done.","PeriodicalId":15418,"journal":{"name":"Journal of Clinical Dermatology","volume":"53 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78126242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Crocin Ameliorated Atopic Dermatitis Induced in Mice by Inhibiting E-Cadherin/AKT Pathway 藏红花素通过抑制E-Cadherin/AKT通路改善小鼠特应性皮炎

Journal of Clinical Dermatology Pub Date : 2020-01-04 DOI: 10.19070/2332-2977-2000054

A. Alyoussef

引用次数: 0

Innate Lymphoid Cells, Diversity of Functions and Plasticity 先天淋巴样细胞，功能多样性和可塑性

Journal of Clinical Dermatology Pub Date : 2019-12-31 DOI: 10.19070/2332-2977-190005e

J. Félix

引用次数: 0

A 19 Month Old Male Child with Xeroderma Pigmentosum-A Case Report 19月龄男童色素性干皮病1例

Journal of Clinical Dermatology Pub Date : 2019-12-11 DOI: 10.11648/J.IJCD.20190202.12

Md. Shohidul Islam Khan, S. Jahan, S. Paul, Mohammad Morshad Alam, M. I. Hasan, D. Chowdhury, K. Shultana, F. Khan, M. Haque

{"title":"A 19 Month Old Male Child with Xeroderma Pigmentosum-A Case Report","authors":"Md. Shohidul Islam Khan, S. Jahan, S. Paul, Mohammad Morshad Alam, M. I. Hasan, D. Chowdhury, K. Shultana, F. Khan, M. Haque","doi":"10.11648/J.IJCD.20190202.12","DOIUrl":"https://doi.org/10.11648/J.IJCD.20190202.12","url":null,"abstract":"Background: Xeroderma Pigmentosum (XP) is a rare autosomal recessive genodermatosis characterized by pigmentary abnormalities, solar skin damage and cutaneous malignancies on sun exposed area of skin and eyes. XP occurs in subjects with molecular defects in the genes involved in nucleotide excision repair (NER) of ultraviolet-induced DNA lesions leading to premature skin and ocular ageing consequent upon cellular apoptosis and other UV-induced degenerative changes. If sufficient DNA damage occurs, there will be cellular transformation and the development of malignancies. Both genetic, as well as environmental factor, play an important role in XP. XP has a >1000-fold increased risk of a cutaneous basal cell or squamous cell carcinoma or malignant melanoma. Case history: In this case report, we mentioned about a 19 month old boy who was diagnosed clinically as a case of Xeroderma Pigmentosum and presented with pigmentary skin changes (generalized hypo and hyper pigmented macule), eye problems, developmental delay, acute respiratory infection and failure to thrive. A multidisciplinary team involving the Pediatrician, Dermatologist and Ophthalmologist evaluated, diagnosed and treated the patient. In this case, XP was diagnosed clinically due to lack of all investigation facilities. This genetic premalignant condition is rarely diagnosed at the district level hospitals in Bangladesh. We report this case to upgrade the knowledge of pediatricians working in the rural areas (primary and secondary level health care facilities) regarding the diagnosis, counseling, treatment modalities and appropriate referral for Xeroderma Pigmentosum. Recommended management should be focused on educating the patient and the parents about effective sun protection and early recognition of cancers. Genetic counseling should be offered for families at risk","PeriodicalId":15418,"journal":{"name":"Journal of Clinical Dermatology","volume":"21 1","pages":"15-19"},"PeriodicalIF":0.0,"publicationDate":"2019-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84590564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Abdominal Trauma in Children: 10-Year Experience in a Teaching Hospital in Enugu, Nigeria 儿童腹部创伤:尼日利亚埃努古一家教学医院的10年经验

Journal of Clinical Dermatology Pub Date : 2019-12-07 DOI: 10.11648/J.IJCD.20190202.11

C. Emeka

{"title":"Abdominal Trauma in Children: 10-Year Experience in a Teaching Hospital in Enugu, Nigeria","authors":"C. Emeka","doi":"10.11648/J.IJCD.20190202.11","DOIUrl":"https://doi.org/10.11648/J.IJCD.20190202.11","url":null,"abstract":"Background: Abdominal traumas are injuries to the abdomen resulting from transfer of energy from the exterior to the abdomen. It is associated with significant morbidity and mortality especially in developing countries. Methodology: Children who presented with abdominal trauma at Enugu State University Teaching Hospital between January 2007 and December 2016 were evaluated. Diagnosis of abdominal trauma was made based on clinical assessment and imaging investigation. Results: Over the ten year period, there were 42 cases of abdominal trauma with male to female ratio of 3.7:1 and mean age of 9.1 years (4-14). Fall from height, accounting for 42.9% of the cases, was the most common cause of abdominal trauma. This is followed by road traffic accident (35.7%), bicycle handle injury 14.3%, gunshot injury 7.1%. Abdominal ultrasound was the most common imaging modality. The spleen was the most injured organ, followed by liver, kidney, and intestine in descending order. Non-operative treatment was successful in 85.3% of the patients while 14.7% had surgery. The mean duration of hospital stay was 9.8 days (1-14) and the mortality was 7.1%. Conclusion: Abdominal trauma affects children of all age groups. In the current study, fall from height was the most common mechanism of injury and the spleen was the most injured organ. Non–operative treatment was the predominant modality of treatment.","PeriodicalId":15418,"journal":{"name":"Journal of Clinical Dermatology","volume":"5 1","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2019-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84258578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0