Chenyu Zhou, Jinlin Wu, E. Xie, L. Dai, Jian Song, R. Zhao, Shiqi Gao, J. Qiu, Cuntao Yu
{"title":"Female Sex Is Not an Independent Risk Factor for Poor Prognosis of Patients with Acute Type A Aortic Dissection Undergoing Surgery","authors":"Chenyu Zhou, Jinlin Wu, E. Xie, L. Dai, Jian Song, R. Zhao, Shiqi Gao, J. Qiu, Cuntao Yu","doi":"10.1155/2023/8889261","DOIUrl":"https://doi.org/10.1155/2023/8889261","url":null,"abstract":"Background and Aim of the Study. The effects of sex on the prognosis of patients with acute type A aortic dissection (ATAAD) have still remained controversial. This study aimed to explore the sex differences in outcomes of ATAAD patients undergoing surgery. Methods. Data of patients with ATAAD who were operated in our center from 2010 to 2018 were retrospectively collected. Data on pre-, intra-, and postoperative courses were analyzed. Propensity score weighting was performed to balance the baseline characteristics. Multivariable logistic regression was used to assess predictors of early mortality in overall female and male patients. Results. A total of 1448 patients were enrolled, including 352 (24.3%) female patients and 1096 (75.7%) male patients. Females were significantly older than males (56.0 vs. 47.8 years, \u0000 \u0000 P\u0000 <\u0000 0.001\u0000 \u0000 ). Dissection was less extensive (Fuwai Ct: 85.8% vs. 91.3%, \u0000 \u0000 P\u0000 =\u0000 0.003\u0000 \u0000 ) and malperfusion syndrome was less frequently diagnosed (Penn Ab: 19.3% vs. 29.7%, \u0000 \u0000 P\u0000 <\u0000 0.001\u0000 \u0000 ) in females. Males experienced more aortic root replacement (Bentall: 14.2% vs. 24.9%, \u0000 \u0000 P\u0000 <\u0000 0.001\u0000 \u0000 ) and total arch replacement combined with frozen elephant trunk (56.8% vs. 75.8%, \u0000 \u0000 P\u0000 <\u0000 0.001\u0000 \u0000 ) with the prolonged operation time (6.1 vs. 6.4 hours, \u0000 \u0000 P\u0000 =\u0000 0.001\u0000 \u0000 ). In contrast, early mortality was higher in females (9.4% vs. 6.1%, \u0000 \u0000 P\u0000 =\u0000 0.036\u0000 \u0000 ). No differences were found in long-term survival and reoperation rates. After propensity score weighting, sex suggested no influence on both early and long-term outcomes. Cardiopulmonary bypass time was an independent risk factor for early mortality in both overall and sex-related populations according to the multivariable logistic regression. Conclusions. In ATAAD, different presentations and surgical strategies were noted in male and female patients. However, there were no significant differences in early and long-term outcomes between sexes after propensity score weighting.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48824844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Arnaout, Yaman Nerabani, Hassan Alhaj Ali, Mohamad Zaher Shahrour, M. Fallaha, I. Arnaout, Ahmad Sajee, Mohamad Morjan, Hussein Al-Kanj
{"title":"Mortality and Survival after Norwood Procedure Comparison between Shunt Type in Patients with Hypoplastic Left Heart Syndrome or Its Variants: A Systematic Review and Meta-Analysis Study","authors":"A. Arnaout, Yaman Nerabani, Hassan Alhaj Ali, Mohamad Zaher Shahrour, M. Fallaha, I. Arnaout, Ahmad Sajee, Mohamad Morjan, Hussein Al-Kanj","doi":"10.1155/2023/8534205","DOIUrl":"https://doi.org/10.1155/2023/8534205","url":null,"abstract":"Background. In the Norwood procedure, a conduit is performed either from the subclavian artery to the pulmonary artery, Blalock–Taussig shunt (mBTs), or from the right ventricle to the pulmonary artery (RV-PA shunt). There are some concerns regarding the two shunts and which one is better according to morbidity and mortality in patients with hypoplastic left heart syndrome or its variants. Methods. We systematically searched PubMed, Web of Science, Scopus, Embase, and Cochrane Library databases from inception to 04/June/2021 to collect articles reporting a comparison of RV-PA shunt and mBTs. Results. Our meta-analysis showed that the mortality rate after 6 months, 1, 2, 3, 4, 5, and 6 years for the mBTS group was 16.3%, 28.6%, 34.8%, 42.4%, 44.6%, 45.1%, and 39.6%, respectively, and for the RV-PAS, 14.8%, 26.6%, 31%, 40.1%, 36.1%, 37.5%, and 34.0%, respectively. The mortality rate was significantly higher in the mBTs group at 1 and 2 years; otherwise, there is no significance differences. Overall complications rate was higher in the mBTs group than in the RV-PAs group (17.8% vs. 8.5%). In contrast, the rate of cardiac complications was higher in the RV-PAS group. Conclusions. The RV-PA shunt had lower mortality and overall complications rate than mBT shunt at the short-term outcome within the first two years, but at the long term, there was no difference between the two shunts. On the other hand, the mBT shunt had a lower incidence of cardiac complications at the early stage after the operations. However, some studies are poor due to the difficulties in conducting original research in this field. Therefore, we recommend conducting systematic reviews and original studies to compare these and other therapeutic procedures for these patients.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42976913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Association of the Cerebral Protection Strategy with Early Mortality and Postoperative Stroke in Acute Type A Aortic Dissection: A Systematic Review and Meta-Analysis","authors":"Caius Mustonen, Mikko Uimonen","doi":"10.1155/2023/3975367","DOIUrl":"https://doi.org/10.1155/2023/3975367","url":null,"abstract":"Objective. The optimal cerebral protection strategy in acute type A aortic dissection (ATAAD) is still without a clear consensus. The purpose of this meta-analysis was to compare the outcome of different cerebral protection strategies on ATAAD patients. Materials and Methods. We conducted a systematic review including all studies concerning surgically managed ATAAD patients between 1.1.2010 and 28.2.2022 and reporting the use of cerebral protection strategies in three large databases (Pubmed, Cochrane library, and Scopus). The main outcome events were 30-day mortality and a postoperative stroke rate. The pooled event rates adjusted by age, gender, CPB duration, circulatory arrest duration, and total arch reconstruction rate were calculated. Results. Overall, 39 articles were included covering a total of 16, 876 ATAAD patients. The estimated adjusted pooled early mortality rate was 10.1% (95% confidence interval [CI] 9.1–11.3%) in the ACP group, 15.9% (13.3–18.9%) in the RCP group, and 11.6% (9.2–14.5%) in the HCA group. Compared to the RCP group, ACP and HCA demonstrated lower early mortality (RCP vs. ACP odds-ratio 1.66 [1.28–2.15], <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\"> <mi>p</mi> </math> < 0.001; RCP vs. HCA odds-ratio 1.45 [1.02–2.07], <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M2\"> <mi>p</mi> </math> = 0.039). The adjusted pooled stroke rate was 9.0% (8.3–9.8%) in the ACP group, 10.5% (9.3–11.7%) in the RCP group, and 9.1% (8.1–10.2%) in the HCA group. Conclusion. Early mortality might be more common in ATAAD patients treated with RCP compared to ACP and HCA. With regards to postoperative stroke, the results were inconclusive despite the trending inferiority of RCP compared to the other strategies.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135643222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left Ventricular Recovery after Transapical Transcatheter Aortic Valve Implantation Compared with Conventional Aortic Valve Replacement in Patients with Aortic Regurgitation and Reduced Ejection Fraction","authors":"Zhiqin Lin, Zheng Xu, Xiaofu Dai, Liangwan Chen","doi":"10.1155/2023/3691715","DOIUrl":"https://doi.org/10.1155/2023/3691715","url":null,"abstract":"Background and Aim of the Study. To evaluate differences in left ventricular recovery after transapical transcatheter aortic valve implantation and conventional aortic valve replacement in patients with aortic regurgitation and reduced left ventricular ejection fraction. Methods. All patients with reduced left ventricular ejection fraction who underwent aortic valve surgery for AR at our institution between January 2015 and November 2021 were retrospectively reviewed. Generalized estimating equations were used to compare left ventricular recovery and remodeling outcomes between the patient groups. Results. A total of 87 cases were included in this study, 36 patients for TA-TAVI and 51 patients for C-AVR. Transapical transcatheter aortic valve implantation was associated with better and faster recovery of left ventricular ejection fraction and left ventricular end-diastolic dimension (adjusted β = 0.002, 95% CI: 0.000 to 0.003, and <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\"> <mi>p</mi> <mo>=</mo> <mn>0.046</mn> </math> ; adjusted β = 0.330, 95% CI: 0.185 to 0.474, and <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M2\"> <mi>p</mi> <mo><</mo> <mn>0.001</mn> </math> , respectively) within the first 3 months postoperatively compared with left ventricular ejection fraction, with the same improvement in New York Heart Association function class (adjusted β = 0.381, 95% CI: −0.349 to 1.111, and <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M3\"> <mi>p</mi> <mo>=</mo> <mn>0.306</mn> </math> ). Conclusions. This study highlights patients who underwent transapical transcatheter aortic valve implantation for aortic regurgitation with reduced left ventricular ejection fraction. However, future randomized controlled prospective clinical trials with longer follow-up durations are required.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135831769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nudge Theory Can Be Used to Optimise Cardiac Surgery Inpatient Management","authors":"Aashray K. Gupta, J. Kovoor, S. Bacchi","doi":"10.1155/2023/7291773","DOIUrl":"https://doi.org/10.1155/2023/7291773","url":null,"abstract":"Nudge theory has influenced the behaviour of millions of individuals across the world; however, the potential power of this approach has yet to be fully utilised in the field of inpatient cardiac surgery. The nudge theory also presents multiple nonalert choice architecture modifications that may be employed. Choice architecture is already influencing decisions made in hospitals every day, whether it has been deliberately designed to promote beneficial behaviours or not. Decision making for cardiac surgery inpatients is already subject to inherent choice architectures, which may be amenable to nudges. The types of choices to which nudges may be employed in the inpatient surgical setting are numerous and may be relevant to medical officers, nursing staff, allied health staff, and patients. Through the strategic development and robust evaluation of choice architecture modification, using the principles of the nudge theory, further optimisation of cardiac surgery inpatient management may be achieved.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44559394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Chen, Dongxu Wang, Yuanchen He, M. Fang, P. Hou, Yiming Tan, Yu Liu, Yan Jin, Liming Yu, Yong Zhang
{"title":"Potential Role of Extracellular CIRP in Total Aortic Arch Replacement under Hypothermic Circulatory Arrest","authors":"K. Chen, Dongxu Wang, Yuanchen He, M. Fang, P. Hou, Yiming Tan, Yu Liu, Yan Jin, Liming Yu, Yong Zhang","doi":"10.1155/2023/6178343","DOIUrl":"https://doi.org/10.1155/2023/6178343","url":null,"abstract":"Objectives. To investigate the potential role of extracellular cold-inducible RNA-binding protein (CIRP) in total aortic arch replacement under hypothermic circulatory arrest. Methods. The serum extracellular CIRP levels at five time points in 96 patients with Stanford A aortic dissection were detected. Overall change trend of CIRP levels at five time points was described, and the risk factors for 30-day mortality after surgery were analyzed. Results. The serum extracellular CIRP levels increased gradually after surgery, starting to rise significantly at approximately 12 h postoperatively, reaching or approaching a peak at approximately 24 h postoperatively, and ceasing to rise significantly after approximately 48 h postoperatively. Age, troponin-I, urodilatin, cooling time, cardiopulmonary bypass time, cross-clamp time, duration of surgery, and CIRP level at the end of surgery in the death group were significantly higher than those in the survival group. Multivariable analysis indicated that CIRP level at the end of surgery, age, urodilatin, and cross-clamp time were independent risk factors for postoperative 30-day mortality. Conclusion. Extracellular CIRP is closely related to the perioperative condition and prognosis of hypothermic circulatory arrest.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41568122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel Echocardiographic Metrics Predict Tricuspid Insufficiency in Pediatric Ebstein Anomaly","authors":"Wei Liu, Chen Wen, Shentu Jin, Yuqi Zhang, Zhongqun Zhu, Lijun Chen, Huiwen Chen","doi":"10.1155/2023/7796087","DOIUrl":"https://doi.org/10.1155/2023/7796087","url":null,"abstract":"Objectives. The tricuspid anterior leaflet is considered important in most repair techniques for Ebstein anomaly (EA). We aim to assess the anterior leaflet morphology using novel metrics and investigate the association of the morphology with recurrent moderately severe or greater tricuspid regurgitation (TR). Methods. Seventy-four paediatric patients with EA undergoing cone reconstruction (CR) between 2010 and 2021 were included. Anterior leaflet mobility (ALM) and anterior leaflet length (ALL) were remeasured on preoperative 2D echocardiography. The prediction accuracies of ALM and ALL-I (ALL indexed to body surface area) for recurrent TR were evaluated using receiver operating characteristic (ROC) curve analyses. Results. The median age of patients was 3.3 years (interquartile range, 1.9–7.1 years). Both ALM and ALL-I correlated with the Carpentier type and GOSH score. Nine patients (12.2%) developed recurrent TR during the one-year follow-up. By univariable logistic regression analyses, ALM (odds ratio [OR], 0.89; 95% CI [confidence interval], 0.82–0.96; \u0000 \u0000 p\u0000 \u0000 = 0.003) and ALL-I (OR, 1.39; 95% CI, 1.08–1.78; \u0000 \u0000 p\u0000 \u0000 = 0.011) were risk factors for recurrent TR. ROC curve analyses showed that ALM (AUC = 0.81) and ALL-I (AUC = 0.77) had better predictive performance for recurrent TR compared with the GOSH score (AUC = 0.68), the Carpentier type (AUC = 0.67), and preoperative TR severity (AUC = 0.58), and the combinations of ALM and ALL-I (AUC = 0.87) improved the predictive performance compared with ALM or ALL-I alone. Conclusions. ALM and ALL-I can help optimize evaluation in the anterior leaflet morphology and predict recurrent TR after CR in pediatric EA.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49452918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Curry Sherard, Savannah Skidmore, K. Shorbaji, B. Welch, K. Bhandari, A. Kilic
{"title":"Improvement in Racial Disparities in Heart Transplantation following the Heart Allocation Policy Change","authors":"Curry Sherard, Savannah Skidmore, K. Shorbaji, B. Welch, K. Bhandari, A. Kilic","doi":"10.1155/2023/5061721","DOIUrl":"https://doi.org/10.1155/2023/5061721","url":null,"abstract":"Objectives. Heart transplantation (HT) is a definitive therapy for refractory heart failure, making it the gold-standard treatment for recipients with end-stage disease. Heart allocation policy (HAP) in the United States was changed on October 18th, 2018. The aim of this study was to assess the effect of the new policy on racial disparities in heart transplantation (HT) outcomes. Methods. The United Network for Organ Sharing (UNOS) registry was used to identify adult recipients undergoing isolated HT between 2010 and 2021. Recipients were stratified into pre-HAP (January 2010 to September 2018) vs. post-HAP (October 2018 to September 2021). Recipient race was classified as White, Black, Hispanic, or other. The primary outcome was post-HT mortality. Cox proportional hazard models were used for risk-adjustment in evaluating the independent effect of race on post-HT mortality. Results. A total of 27,403 recipients underwent HT in 143 centers during study period. The proportion of non-Whites undergoing HT increased in the post-HAP era: (pre-HAP: White 66.0%, Black 21.2%, Hispanic 8.2%, Other 4.6% versus post-HAP: White 62.5%, Black 23.2%, Hispanic 9.5%, Other 4.8%; \u0000 \u0000 p\u0000 <\u0000 0.001\u0000 \u0000 ). In risk-adjusted analysis, Black recipients were at higher risk of post-HT mortality in the pre-HAP era (HR 1.31, 95% CI 1.22–1.41; \u0000 \u0000 p\u0000 <\u0000 0.001\u0000 \u0000 ) but not in the post-HAP era (HR 1.12, 95% CI 0.03–1.34; \u0000 \u0000 p\u0000 =\u0000 0.222\u0000 \u0000 ) compared to White recipients. Other non-White recipients had comparable risk-adjusted post-HT mortality rates compared to White recipients both in the pre-HAP and post-HAP eras. Conclusions. Under the new heart allocation system, a higher percentage of recipients are non-White. In addition, racial disparities in HT outcomes have improved with Black recipients no longer having an increased risk-adjusted mortality following HT.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48837199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Yuan, Wenrui Ma, J. Cui, Junjiang Liu, Zhao-hua Yang, Shou-guo Yang, Hongqiang Zhang, Fanshun Wang, Huan Liu, Chunsheng Wang, Xiaoning Sun
{"title":"Mildly Elevated Pulmonary Artery Systolic Pressure is Associated with Extracorporeal Membrane Oxygenation Support after Heart Transplantation","authors":"L. Yuan, Wenrui Ma, J. Cui, Junjiang Liu, Zhao-hua Yang, Shou-guo Yang, Hongqiang Zhang, Fanshun Wang, Huan Liu, Chunsheng Wang, Xiaoning Sun","doi":"10.1155/2023/8877476","DOIUrl":"https://doi.org/10.1155/2023/8877476","url":null,"abstract":"Background. Pulmonary hypertension is a well-known risk factor for hemodynamic instability after heart transplantation. However, it remains unclear whether a mild elevation of pulmonary artery systolic pressure (PASP) is associated with higher risks of graft dysfunction and resultant extracorporeal membrane oxygenation (ECMO) support. Methods. From 2016 to 2021, 102 adult recipients undergoing orthotopic heart transplantation at our institution were investigated (mean age, 48.5 ± 13.2 years; 22.5% female). This study cohort was stratified into 3 groups based on the PASP measured by right heart catheterization before surgery: >50 mmHg, 35–50 mmHg, and <35 mmHg. The primary end point was ECMO support after procedure. Results. ECMO was implemented in 24 (23.5%) patients due to difficult weaning from cardiopulmonary bypass or cardiac low output in the intensive care unit, which was likely to be associated with higher mortality (\u0000 \u0000 P\u0000 =\u0000 0.053\u0000 \u0000 ). Age, gender, comorbidities, preoperative medications, and graft ischemia time were comparable across the 3 groups. The use of ECMO was significantly more common in patients with baseline PASP >50 mmHg (11/36, 30.6%) and 35–50 mmHg (12/38, 31.6%), while only 1 (3.6%) patient with baseline PASP <35 mmHg required ECMO support after transplant (\u0000 \u0000 P\u0000 =\u0000 0.007\u0000 \u0000 ). Multivariate logistic models demonstrated that PASP (odds ratio = 2.34; \u0000 \u0000 P\u0000 =\u0000 0.028\u0000 \u0000 ) and cardiopulmonary bypass time (odds ratio = 1.01; \u0000 \u0000 P\u0000 <\u0000 0.001\u0000 \u0000 ) were independent risk factors for postoperative ECMO. Conclusions. A mild elevation of pretransplant PASP (e.g., 35–50 mmHg) is related to low cardiac output and subsequent ECMO after heart transplantation, for which prompt administration of vasodilators before transplant may be protective.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46929107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3D-Printed Models for Multidisciplinary Discussion of Congenital Heart Diseases","authors":"M. Song, Sang Yoon Lee, S. Yoon, Jeong‐Wook Seo","doi":"10.1155/2023/8899573","DOIUrl":"https://doi.org/10.1155/2023/8899573","url":null,"abstract":"Background. Congenital heart defects (CHDs) are complex three-dimensional (3D) lesions with variable anatomies that present therapeutic challenges. The application of a patient-specific3D-printed model in preoperative planning and communication in medical practice can contribute to a complete understanding of the intracardiac and vascular anatomy. This study aimed to prospectively investigate the clinical value of a 3D CHD model in multidisciplinary discussions. Methods. Between August 2019 and April 2021, 19 patients with complex CHDs before surgery were prospectively enrolled in this study. Eight to 14 medical specialists participated in multidisciplinary discussions using patient-specific 3D models. A subjective satisfaction questionnaire, comprising 12 questions to be answered on a 10-point scale, was distributed. Results. Twenty 3D-printed anatomic models of 19 patients were used. The median age and weight of the enrolled patients were 0.8 years (range, 5 days to 43 years) and 9.6 kg (range, 2.8–54 kg), respectively. The most common underlying disease was a double outlet of the right ventricle. The mean scores for understanding spatial orientation, ease of communication between clinicians during discussions, prediction of surgical complications, and information additional to conventional 2D imaging were 9.4 ± 1.1, 9.4 ± 0.9, 9.0 ± 1.1, and 9.2 ± 0.4, respectively. The competency and comfort scores for each patient’s surgical plan increased significantly after using the 3D-printed model (from 6.2 ± 1.6 to 9.2 ± 0.9, \u0000 \u0000 p\u0000 \u0000 < 0.001 and from 6.3 ± 1.6 to 9.2 ± 0.8, \u0000 \u0000 p\u0000 \u0000 < 0.001, respectively). Conclusions. Patient-specific 3D models, for patients with complex CHDs, improved the understanding of the disease and facilitated multidisciplinary discussions and surgical decision-making. However, because outcomes were mainly evaluated by subjective reports, the possibility of other unknown factors affecting the outcomes should be considered. Trial Registration. This trial is registered with D-1904-031-1024.","PeriodicalId":15367,"journal":{"name":"Journal of Cardiac Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45345058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}