发布求助
文献互助 智能选刊 最新文献

International Journal of Dermatology and Clinical Research最新文献

筛选
英文 中文
Low PD-1 expression and no prognostic impact in early-stage Mycosis Fungoides: 61 patients retrospective cohort analysis 61例早期蕈样真菌病患者PD-1低表达及无预后影响
International Journal of Dermatology and Clinical Research Pub Date : 2019-07-20 DOI: 10.17352/2455-8605.000032
G. Amorim, D. Quintella, João Paulo Niemeyer Corbellini, L. C. Ferreira, M. Ramos‐e‐Silva, T. Cuzzi
{"title":"Low PD-1 expression and no prognostic impact in early-stage Mycosis Fungoides: 61 patients retrospective cohort analysis","authors":"G. Amorim, D. Quintella, João Paulo Niemeyer Corbellini, L. C. Ferreira, M. Ramos‐e‐Silva, T. Cuzzi","doi":"10.17352/2455-8605.000032","DOIUrl":"https://doi.org/10.17352/2455-8605.000032","url":null,"abstract":"Background: Mycosis fungoides (MF) is an indolent behavior cutaneous T-cell lymphoma. Most \u0000patients present a slowly progressive course, over many years. However, some patients evolve early \u0000towards advanced stages of the disease, despite adequate treatment, having therefore, a worse prognosis. Increasing knowledge of risk factors that contribute to a better prognostic evaluation is considered of interest.","PeriodicalId":153509,"journal":{"name":"International Journal of Dermatology and Clinical Research","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115703695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nε-(carboxymethyl) lysine represses hair follicle formation by inhibiting Sonic hedgehog expression in a NF-κB-independent manner ε-(羧甲基)赖氨酸以不依赖于NF-κ b的方式抑制Sonic hedgehog基因的表达，从而抑制毛囊的形成
International Journal of Dermatology and Clinical Research Pub Date : 2019-02-02 DOI: 10.17352/2455-8605.000031
Kosuke Tanaka, Kana Mizuno, Chika Natsume, M. Takanishi, Y. Shimada, R. Saito, N. Fujita, T. Fujita
{"title":"Nε-(carboxymethyl) lysine represses hair follicle formation by inhibiting Sonic hedgehog expression in a NF-κB-independent manner","authors":"Kosuke Tanaka, Kana Mizuno, Chika Natsume, M. Takanishi, Y. Shimada, R. Saito, N. Fujita, T. Fujita","doi":"10.17352/2455-8605.000031","DOIUrl":"https://doi.org/10.17352/2455-8605.000031","url":null,"abstract":"Ne-(carboxymethyl) lysine (CML), an advanced glycation end product (AGE), is an aging factor produced by glycation of protein. Higher levels of AGE in skin tissue are related to skin elasticity, but how CML that has accumulated in the skin affects hair follicle formation is unclear. This study constructed a simple model that mimics accumulated glycation from feeding by intradermally injecting Ne-(carboxymethyl) lysine (CML), and examined the effects on the morphogenesis of hair follicles (HF). The results showed weakening of the hair shaft and HF formation by CML. The in vitro inhibitory effect of CML on wound healing of dermal papilla cells (DPC) suggested that the mechanism influences the proliferation and migration of DPC, which are essential for HF morphogenesis.","PeriodicalId":153509,"journal":{"name":"International Journal of Dermatology and Clinical Research","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116454808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare disease more common than perceived: Two case studies and brief review of IgA Vasculitis 一种罕见的疾病，比想象的更常见:IgA血管炎的两个案例研究和简要回顾
International Journal of Dermatology and Clinical Research Pub Date : 2019-01-25 DOI: 10.17352/2455-8605.000030
Lydia Shedlofsky Do, Chelsea Crist
{"title":"A rare disease more common than perceived: Two case studies and brief review of IgA Vasculitis","authors":"Lydia Shedlofsky Do, Chelsea Crist","doi":"10.17352/2455-8605.000030","DOIUrl":"https://doi.org/10.17352/2455-8605.000030","url":null,"abstract":"Immunoglobulin A (IgA) Vasculitis, more commonly known as Henoch-Schonlein Purpura (HSP), is a disorder which causes inflammation and bleeding in the small blood vessels of the skin, joints, intestines, and kidneys. We report 2 cases of IgA vasculitis found in a rural emergency department: 1) HSP in an 8-year-old male who was initially misdiagnosed with insect bites 2) HSP in an adult male patient. We present both cases and a literature review, indicating that low incidence may be secondary to under diagnosis, arguing for a need of further education on the subject.","PeriodicalId":153509,"journal":{"name":"International Journal of Dermatology and Clinical Research","volume":"258 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123287257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated bilateral facial palsy due to chicken pox- An unique presentation 水痘引起的孤立性双侧面瘫-一种独特的表现
International Journal of Dermatology and Clinical Research Pub Date : 2019-01-12 DOI: 10.17352/2455-8605.000029
N. Chatterjee, C. Chatterjee
{"title":"Isolated bilateral facial palsy due to chicken pox- An unique presentation","authors":"N. Chatterjee, C. Chatterjee","doi":"10.17352/2455-8605.000029","DOIUrl":"https://doi.org/10.17352/2455-8605.000029","url":null,"abstract":"A nineteen year old girl presented with rashes of chicken pox and inability to close both eyes properly for two days. She had difficulty in eating and smiling.","PeriodicalId":153509,"journal":{"name":"International Journal of Dermatology and Clinical Research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115181792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incontinentia Pigmenti: an unusual and fast presentation 色素失禁:一种不寻常且快速的表现
International Journal of Dermatology and Clinical Research Pub Date : 2018-12-20 DOI: 10.17352/2455-8605.000028
Eduardo Duarte Sobrosa, Bruno Evangelista de Toledo, A. Sadovsky
{"title":"Incontinentia Pigmenti: an unusual and fast presentation","authors":"Eduardo Duarte Sobrosa, Bruno Evangelista de Toledo, A. Sadovsky","doi":"10.17352/2455-8605.000028","DOIUrl":"https://doi.org/10.17352/2455-8605.000028","url":null,"abstract":"Incontinentia pigmenti is a rare X-linked neuroectodermal dysplasia estimated to occur in approximately 1:50,000 births. It’s first clinical manifestations are unique cutaneous lesions comprehending four different stages that emerge throughout the first year of life and persist until adolescence. One third of these patients develop central nervous system and ocular manifestations, causing great disability. The authors report the case of a patient with vesicular cutaneous lesions within 5 days after birth, with a fast and uncommon evolution. Although rare, the early identification of this disorder can prompt thorough investigation of associated comorbidities and adequate familiar and medical assistance.","PeriodicalId":153509,"journal":{"name":"International Journal of Dermatology and Clinical Research","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123238460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信