Journal of chemical and pharmaceutical research最新文献_第3页

Determination of pH-BOD-COD and degradation in batang arau watersheds at Padang city 巴东市巴塘阿劳流域pH-BOD-COD测定及其降解

Journal of chemical and pharmaceutical research Pub Date : 2015-12-30 DOI: 10.31227/osf.io/efdzj

I. Dewata, R. Zainul

{"title":"Determination of pH-BOD-COD and degradation in batang arau watersheds at Padang city","authors":"I. Dewata, R. Zainul","doi":"10.31227/osf.io/efdzj","DOIUrl":"https://doi.org/10.31227/osf.io/efdzj","url":null,"abstract":"This research aims to determine the pH, BOD and COD in river basin region and its relation to the occurrence of damage to the environment. The study was conducted by sampling at six locations representing the upstream region, the central region and the region downstream/estuary for four years, from 2011 until 2014. The sampling locations in the watershed Batang Arau at Padang city, include Lubuk Paraku (section 1), Banyan Lubuk Kilangan (section 2), the center, Bridges Lubeg by pass (section 3), Bridge Aur Duri / Pulau Aia (section 4), downstream, Bridges Aru Padang (section 5) and Muaro Bridge Siti Nurbaya (section 6 ). In the Upstream, for the parameters pH, BOD and COD in 2011 to 2014 received a range of changes in pH of 6-9, unless the parameters BOD in 2012 of about 4.35 mg/L. In the central region (middlestream), namely BOD content of 4.35 mg/L (2011), 4.54 mg/L (2012), 3.36 mg/L (2013) and 2.56 mg/L (2014), approaching the quality standards was set at 3 mg/L. While the pH and COD are below the quality standards every year. In the downstream, the results of BOD of 17.21 mg/L (2011), 21.25 mg/L (2012), 5.04 mg/L (2013) and 3.42 mg/L (2014). Meanwhile, COD 47.5 mg/L (2011), 57.76 mg/L (2012), 11.17 mg/L (2013) and 20, 5 mg/L (2014), while the quality standards for COD by 25 mg/L, and pH parameters within normal limits. From this research, we reported that watersheds degradation has been in downstream area (section 5 and 6), but in upstream and middlestream was still normally and not degraded.","PeriodicalId":15344,"journal":{"name":"Journal of chemical and pharmaceutical research","volume":"151 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83368965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Private Placement Discount of Chinese Listed Companies Based on the Perspective of the Investors’ Sentiment 基于投资者情绪视角的中国上市公司定向增发折价

Journal of chemical and pharmaceutical research Pub Date : 2013-12-01 DOI: 10.1007/978-3-642-38442-4_13

Jun Yu, Zhu-bao Wei, Shu-zhen Wang, J. Tang

引用次数: 3

An equation of state for nonaqueous electrolyte solutions 非水电解质溶液的状态方程

Journal of chemical and pharmaceutical research Pub Date : 2012-10-31 DOI: 10.4236/ACES.2012.24061

Zheng Han

引用次数: 2

Molecular determinants of ligand binding at the human histamine H₁ receptor: Site-directed mutagenesis results analyzed with ligand docking and molecular dynamics studies at H₁ homology and crystal structure models. 人组胺H1受体配体结合的分子决定因素:通过配体对接和H1同源性和晶体结构模型的分子动力学研究分析位点定向突变结果。

Journal of chemical and pharmaceutical research Pub Date : 2012-06-01

Tania C Cordova-Sintjago, Lijuan Fang, Martijn Bruysters, Rob Leurs, Raymond G Booth

{"title":"Molecular determinants of ligand binding at the human histamine H1 receptor: Site-directed mutagenesis results analyzed with ligand docking and molecular dynamics studies at H1 homology and crystal structure models.","authors":"Tania C Cordova-Sintjago, Lijuan Fang, Martijn Bruysters, Rob Leurs, Raymond G Booth","doi":"","DOIUrl":"","url":null,"abstract":"The human histamine H1 G-protein coupled receptor (GPCR) is an important drug target for inflammatory, sleep, and other neuropsychiatric disorders. To delineate molecular determinants for ligand binding for drug discovery purposes, human H1 receptor models were built by homology to the crystal structure of the human β2 adrenoceptor (β2AR) and from the recently reported crystal structure of the human H1 receptor complex with doxepin at 3.1 Å (PDB code 3RZE). Ligand affinity of histamine and the H1 antagonists mepyramine and (2S, 4R)-(-)-trans-4-phenyl-2-N, N-dimethylaminotetralin (PAT) at wild type and point-mutated (D3.32A, Y3.33A, W4.56A, F5.47A, W6.48A, Y6.51A, F6.52A, F6.55A, Y7.43A) human H1 receptors were determined experimentally and results analyzed by ligand docking and molecular dynamic studies at WT and point-mutated H1 receptor models. Differences in ligand binding affinities correlated to differences in ligand binding modes at models built according to homology or crystal structure, indicating, both models are accurate templates for predicting ligand affinity for H1 drug design.","PeriodicalId":15344,"journal":{"name":"Journal of chemical and pharmaceutical research","volume":"4 6","pages":"2937-2951"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085681/pdf/nihms496523.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32494199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RSK2 Binding Models Delineate Key Features for Activity. RSK2绑定模型描述了活性的关键特征。

Journal of chemical and pharmaceutical research Pub Date : 2010-01-01

Rick Gussio, Michael J Currens, Dominic A Scudiero, Jeffrey A Smith, Deborah A Lannigan, Robert H Shoemaker, Dan W Zaharevitz, Tam Luong Nguyen

引用次数: 0