Research in Pediatrics & Neonatology最新文献

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Food Intolerance and Malabsorption Syndrome in Children: Signs and Symptoms 儿童食物不耐受和吸收不良综合征:体征和症状
Research in Pediatrics & Neonatology Pub Date : 2018-09-07 DOI: 10.31031/RPN.2018.02.000551
T. Yaroshevska
{"title":"Food Intolerance and Malabsorption Syndrome in Children: Signs and Symptoms","authors":"T. Yaroshevska","doi":"10.31031/RPN.2018.02.000551","DOIUrl":"https://doi.org/10.31031/RPN.2018.02.000551","url":null,"abstract":"Issues of food intolerance formation in children are currently relevant due to high prevalence and difficulties with diagnostics [1-3]. Environmental pollution can negatively affect quality of food. There are a significant number of food components, which human body is not adapted to during the evolution (e.g. stabilizers, preservatives, transgenic fats, refined products, etc.). Children have anatomical and physiological features that are predisposing to formation of malabsorption syndrome, such as delayed start of digestive enzyme systems, violation of gastrointestinal motility regulation, immaturity of the intestinal microbiocenosis, high intestinal penetration and others.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132533176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of a Long Term Ventricular Assist Device with a Modified Circuit and Modified Care Model for Short Term Extracorporeal Support: An Institutional Experience 在短期体外支持中使用改良电路和改良护理模式的长期心室辅助装置:一项机构经验
Research in Pediatrics & Neonatology Pub Date : 2018-08-17 DOI: 10.31031/RPN.2018.02.000550
Tanya Chadha, Shamsur Chowdhury, E. Ceithaml, M. Shillingford
{"title":"Use of a Long Term Ventricular Assist Device with a Modified Circuit and Modified Care Model for Short Term Extracorporeal Support: An Institutional Experience","authors":"Tanya Chadha, Shamsur Chowdhury, E. Ceithaml, M. Shillingford","doi":"10.31031/RPN.2018.02.000550","DOIUrl":"https://doi.org/10.31031/RPN.2018.02.000550","url":null,"abstract":"The industry of supportive mechanical devices has the pressure of needing to produce products that are reliable, durable, cost effective, and require low maintenance and oversight. In the pediatric population, mechanical support for patients with congenital heart disease is an ongoing challenge. Here we briefly describe our institution’s experience in providing short term extracorporeal support for pediatric congenital heart disease patients through innovative modifications to traditional extracorporeal circuitry and strategies.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133435816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Holoprosencephaly: A Case Study for Communicative and Swallowing Management 无前脑畸形:交流与吞咽治疗的个案研究
Research in Pediatrics & Neonatology Pub Date : 2018-08-13 DOI: 10.31031/RPN.2018.02.000547
M. Ciyiltepe, Z. U. Coskun
{"title":"Holoprosencephaly: A Case Study for Communicative and Swallowing Management","authors":"M. Ciyiltepe, Z. U. Coskun","doi":"10.31031/RPN.2018.02.000547","DOIUrl":"https://doi.org/10.31031/RPN.2018.02.000547","url":null,"abstract":"Holoprosencephaly (HP) is a developmental central nervous system defect characterized by advanced facial anomalies resulting from the complete separation of two lobes of the cerebral hemispheres [1]. Prevalence is 1.31 in 10,000 births [2,3]. There is a parallel relationship between the combination of different etiological factors in different contributions and the changing clinical picture of the disease. Autosomal dominant and autosomal recessive inherited forms are reported in the literature [4,5]. Considering the studies on holoprosencephaly, developmental, neurological and medical problems were found in children with holoprosencephaly Cohen, 1982; Ersin & Ertugrul, 2005 [6,7]. Table 1 lists the physical findings that can be seen in individuals with HP. Postnatal care of HP is multidisciplinary, symptomatic and long-lasting cognitive and physical supportive therapy. Prognosis depends on the size of the associated medical and neurological disorders (Table 2). Table 1: Physical characteristics that can be seen in","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129311021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Tuberculosis 先天性结核病
Research in Pediatrics & Neonatology Pub Date : 2018-08-13 DOI: 10.31031/rpn.2018.02.000546
N. Narain
{"title":"Congenital Tuberculosis","authors":"N. Narain","doi":"10.31031/rpn.2018.02.000546","DOIUrl":"https://doi.org/10.31031/rpn.2018.02.000546","url":null,"abstract":"Tuberculosis (TB) is a global public health problem with WHO South-East Asia Region accounting for about 45% of total cases. Tuberculosis is the ninth leading cause of death worldwide and is the leading infectious cause, ranking above HIV/AIDS. In 2016, about 1.3 million HIV negative people died due to tuberculosis [1]. However, Congenital Tuberculosis (CTB) is extremely rare condition with only less than 400 cases being reported thus far [2,3]. As the diagnosis and thus the treatment are often delayed, it has a mortality rate of almost 50% and about 22% in even those who receive treatment [4].","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125650820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Pyloric Stenosis in Preterm Identical Twins of a Triplet Birth with a Review of Pyloric Stenosis in Premature Neonates 三胞胎早产同卵双胞胎幽门狭窄与早产儿幽门狭窄回顾
Research in Pediatrics & Neonatology Pub Date : 2018-08-13 DOI: 10.31031/RPN.2018.02.000545
Darlene Ac, P. Dd
{"title":"Pyloric Stenosis in Preterm Identical Twins of a Triplet Birth with a Review of Pyloric Stenosis in Premature Neonates","authors":"Darlene Ac, P. Dd","doi":"10.31031/RPN.2018.02.000545","DOIUrl":"https://doi.org/10.31031/RPN.2018.02.000545","url":null,"abstract":"Pyloric stenosis occurs in 1 of every 200-300 live births and is four times more common in males than in females. Reports of pyloric stenosis in premature neonates are rare. We present a case of pyloric stenosis in premature female identical twins of a triplet birth whose father also had pyloric stenosis. The incidence of pyloric stenosis in premature infants and in identical twins, the age and manner of presentation and the clinical courses of these infants is presented. The potential mode of genetic inheritance is also reviewed.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124534052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continuous Hand Hygiene Monitoring Associated with a Two-Year Elimination of Central Line Associated Bloodstream Infections in the NICU 连续手卫生监测与两年消除新生儿重症监护病房中心静脉相关血流感染相关
Research in Pediatrics & Neonatology Pub Date : 2018-08-09 DOI: 10.31031/RPN.2018.02.000544
T. Zahouani, Zenaida Reyno, Suraiya Jahan, Lillian Diaz, Melba Talan, Ronald Bainbridge, Y. Sitnitskaya
{"title":"Continuous Hand Hygiene Monitoring Associated with a Two-Year Elimination of Central Line Associated Bloodstream Infections in the NICU","authors":"T. Zahouani, Zenaida Reyno, Suraiya Jahan, Lillian Diaz, Melba Talan, Ronald Bainbridge, Y. Sitnitskaya","doi":"10.31031/RPN.2018.02.000544","DOIUrl":"https://doi.org/10.31031/RPN.2018.02.000544","url":null,"abstract":"Hand Hygiene (HH) is the single most important method of preventing Central Line-Associated Bloodstream Infections (CLABSIs). We conducted a continuous 15 months long Performance Improvement project of HH monitoring in the NICU. Overt audit was conducted by trained unit staff, using modified World Health Organization Hand Hygiene Observation Tool. The data collected from October 2015 to December 2016 was entered into a departmental database. Of a total of 1466 observation, HH was observed 591, 40.3% times in nurses, 335, 22.9% times in resident and attending physicians, 148, 10.1% in Respiratory Therapists, and 392, 26.7% times in other ancillary staff. Most observations were conducted during the 0800-1600day shift (768, 52.4%), followed by the 1600-0000 evening shift (358, 24.4%), and then by the 0000-0800night shift (340, 23.2%). HH before touching patient was observed most commonly. Overall HH compliance rate increased from the pre-project nadir of 63% to 99.9% during the project period. Only 4 fallouts were identified, all during the day shift. Of these, 3 fallouts were observed in nurses, and 1 in a resident physician. In each instance education was provided in real-time. The interim analysis was shared at monthly unit staff meetings. After the PI project was completed, HH was observed by Head/Charge Nurses and Infection control personnel. From January 2017 to January 2018 HH compliance rate in NICU remained at 100%. There were no CLABSI events for a total of 27 months. Our experience is consistent with previous reports suggesting that education and feedback are the most successful strategies in achieving high HH compliance. We believe that combining real time education with feedback is as important as routine sharing of performance indicators with the multidisciplinary unit team. A positive after-effect in the post PI project phase demonstrates a change in the safety culture of our NICU.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122087866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single Dose Epidural Block for Infra Umbilical Surface Surgery in Children, a Surgeon’s Perspective 单剂量硬膜外阻滞用于儿童脐下表面手术,一个外科医生的观点
Research in Pediatrics & Neonatology Pub Date : 2018-07-19 DOI: 10.31031/rpn.2018.02.000541
V. Gharpure
{"title":"Single Dose Epidural Block for Infra Umbilical Surface Surgery in Children, a Surgeon’s Perspective","authors":"V. Gharpure","doi":"10.31031/rpn.2018.02.000541","DOIUrl":"https://doi.org/10.31031/rpn.2018.02.000541","url":null,"abstract":"Choice of anesthetic is a difficult decision considering the many options available these days. Each technique has its unique set of difficulties and complications. Anesthesia technique has to be chosen depending upon type of surgery, condition of patient, duration of surgery, safety, and finally cost. It should be possible to select a technique which provides optimum effect at the least possible cost, without compromising safety at any point.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122720283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adolescent Systemic Hypertension: Late Diagnosis of Coarctation of the Aorta 青少年全身性高血压:主动脉缩窄的晚期诊断
Research in Pediatrics & Neonatology Pub Date : 2018-07-16 DOI: 10.31031/RPN.2018.02.000539
M. Giuffre
{"title":"Adolescent Systemic Hypertension: Late Diagnosis of Coarctation of the Aorta","authors":"M. Giuffre","doi":"10.31031/RPN.2018.02.000539","DOIUrl":"https://doi.org/10.31031/RPN.2018.02.000539","url":null,"abstract":"The morbidity and mortality rates are low for patients undergoing treatment, for both surgical or catheter interventions, though long-term follow-up is required for complications. Today the diagnosis is often made prenatally with the advent of fetal echocardiography; however, approximately 30% of neonates with coarctation remain undiagnosed upon discharge after delivery. This cardiac defect generally results in left ventricular pressure overload and the patient presentation often varies with the severity of the left ventricular outflow tract obstruction. Additionally, coarctation may be associated with other cardiac defects, as well as chromosomal abnormalities such as Turner syndrome. Case Description A 14-year-old boy was referred to our community pediatric cardiology outpatient clinic for an incidental finding of systemic hypertension that was noted by the patient’s family physician on routine evaluation. The patient was completely asymptomatic, with no visual changes, no headaches, and had a normal activity profile by history. He had an unremarkable past medical history and also had a family history of late-onset hypertension. Abstract Coarctation of the aorta accounts for 5–7% of all the cases of congenital heart disease, with an estimated incidence of approximately 3 cases per 10,000 births. Coarctation of the aorta typically presents in the neonatal or early childhood period. The less severe coarctation patients may have subtle clinical findings such as elevated upper limb blood pressure, diminished femoral pulses, and a systolic ejection murmur that often transmits to the back. This case demonstrates that coarctation can be seen in the otherwise healthy adolescent population.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115302881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Renin-Angiotensin System Components in Hypertension During Pregnancy 肾素-血管紧张素系统成分在妊娠高血压中的作用
Research in Pediatrics & Neonatology Pub Date : 2018-07-02 DOI: 10.31031/RPN.2018.02.000537
XuanJin Jin
{"title":"Role of Renin-Angiotensin System Components in Hypertension During Pregnancy","authors":"XuanJin Jin","doi":"10.31031/RPN.2018.02.000537","DOIUrl":"https://doi.org/10.31031/RPN.2018.02.000537","url":null,"abstract":"Background: Hypertension is common disease amongst women with pregnancy. It is associated with significant maternal, fetal and infant morbidity. Current research on the mechanism of the hypertensive disorders is limited. The renin-angiotensin system (RAS) is a hormone signaling cascade that regulates blood pressure and systemic electrolyte and fluid balance. Our study was designed to focus on the mechanism of gestational hypertension before preeclampsia occurred, exploring the change in both circulating RAS and local RAS. Methods: The human kidney tissue were collected from patients suffered renal tumor (n: 5) or chronic renal insufficiency (n: 25). The human placental tissues were collected from woman with normal pregnancies (n: 35) and gestational hypertension (n: 21). There is no significant difference in maternal age between normal and gestational hypertension subjects. All the participants received written information, and signed the consent. Results: Before delivery, the circulating PRL and Ang II concentration in the gestational hypertension is significantly lower than that in normal pregnancy. There is no significant difference between gestational hypertension and normal pregnancy after delivery. In the local RAS, AT1, Ang II and Ang 1-7 levels in gestational hypertension placenta were significantly higher than normal pregnancy. There is no statistical difference of renin, AGT, and ACE, ACE2 between the two subjects. Conclusion: The change of Ang (1-7) expression in our study is different from the previous studies in preeclampsia. More attention should be put on the balance of Ang II and Ang (1-7).","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131276237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Childhood Gastric Teratoma: A Case Report 儿童胃畸胎瘤1例报告
Research in Pediatrics & Neonatology Pub Date : 2018-06-11 DOI: 10.31031/rpn.2018.02.000535
P. Halder, K. Mandal, A. Das, B. Debnath
{"title":"Childhood Gastric Teratoma: A Case Report","authors":"P. Halder, K. Mandal, A. Das, B. Debnath","doi":"10.31031/rpn.2018.02.000535","DOIUrl":"https://doi.org/10.31031/rpn.2018.02.000535","url":null,"abstract":"Gastric teratoma is relatively rare type of extra gonadal germ cell tumor which comprises <1% of all teratomas. It usually presents with abdominal mass and features of gastric outlet obstruction with or without gastrointestinal bleeding. Complete excision of the tumor is the best mode of treatment. Here, we report a case of gastric teratoma in a two month old male child where we had to go for partial gastrectomy owing to complete removal of the tumor.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115832571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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