Journal of Biophysics最新文献

Corrigendum to “Structural Stability, Transitions, and Interactions within SoxYZCD-Thiosulphate from Sulfurimonas denitrificans: An In Silico Molecular Outlook for Maintaining Environmental Sulphur Cycle” 《反硝化硫单胞菌soxyzcd -硫代硫酸盐的结构稳定性、跃迁和相互作用:维持环境硫循环的硅分子展望》的勘误

Journal of Biophysics Pub Date : 2016-12-20 DOI: 10.1155/2016/7905302

Sujay Ray, A. Banerjee

引用次数: 0

Detection of Gait Modes Using an Artificial Neural Network during Walking with a Powered Ankle-Foot Orthosis 利用人工神经网络检测动力踝足矫形器行走时的步态模式

Journal of Biophysics Pub Date : 2016-12-13 DOI: 10.1155/2016/7984157

Mazharul Islam, E. Hsiao-Wecksler

{"title":"Detection of Gait Modes Using an Artificial Neural Network during Walking with a Powered Ankle-Foot Orthosis","authors":"Mazharul Islam, E. Hsiao-Wecksler","doi":"10.1155/2016/7984157","DOIUrl":"https://doi.org/10.1155/2016/7984157","url":null,"abstract":"This paper presents an algorithm, for use with a Portable Powered Ankle-Foot Orthosis (i.e., PPAFO) that can automatically detect changes in gait modes (level ground, ascent and descent of stairs or ramps), thus allowing for appropriate ankle actuation control during swing phase. An artificial neural network (ANN) algorithm used input signals from an inertial measurement unit and foot switches, that is, vertical velocity and segment angle of the foot. Output from the ANN was filtered and adjusted to generate a final data set used to classify different gait modes. Five healthy male subjects walked with the PPAFO on the right leg for two test scenarios (walking over level ground and up and down stairs or a ramp; three trials per scenario). Success rate was quantified by the number of correctly classified steps with respect to the total number of steps. The results indicated that the proposed algorithm's success rate was high (99.3%, 100%, and 98.3% for level, ascent, and descent modes in the stairs scenario, respectively; 98.9%, 97.8%, and 100% in the ramp scenario). The proposed algorithm continuously detected each step's gait mode with faster timing and higher accuracy compared to a previous algorithm that used a decision tree based on maximizing the reliability of the mode recognition.","PeriodicalId":15261,"journal":{"name":"Journal of Biophysics","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91366625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Structural Stability, Transitions, and Interactions within SoxYZCD-Thiosulphate from Sulfurimonas denitrificans: An In Silico Molecular Outlook for Maintaining Environmental Sulphur Cycle 反硝化硫单胞菌soxyzcd -硫代硫酸盐的结构稳定性、跃迁和相互作用:维持环境硫循环的硅分子前景

Journal of Biophysics Pub Date : 2016-09-29 DOI: 10.1155/2016/8683713

Sujay Ray, A. Banerjee

{"title":"Structural Stability, Transitions, and Interactions within SoxYZCD-Thiosulphate from Sulfurimonas denitrificans: An In Silico Molecular Outlook for Maintaining Environmental Sulphur Cycle","authors":"Sujay Ray, A. Banerjee","doi":"10.1155/2016/8683713","DOIUrl":"https://doi.org/10.1155/2016/8683713","url":null,"abstract":"Thiosulphate oxidation (an essential mechanism) serves to maintain the global sulphur cycle. Earlier experimental and computational studies dealt with environmental thiosulphate oxidation but none dealt with thiosulphate oxidation from deep ocean belts. Wet-laboratory experimental research shows that epsilon-proteobacteria Sulfurimonas denitrificans possess sox (sulphur-oxidizing) operon and perform thiosulphate oxidation efficiently underneath the oceans. From this specific sox operon, SoxCD complex recycles the thiosulphate-bound SoxY from SoxYZ complex to balance the environmental sulphur cycle. So, four chief proteins were variedly modeled and relevant simulated interactive structures were obtained. The final simulated tetraprotein complex (SoxYZCD) from docked SoxYZ and SoxCD complexes was disclosed to be a highly interactive one with predominant ionic residues. Free energy of folding, solvent accessibility, and conformational shifts (coil-like conformation to helices and sheets) were observed in SoxYZ complex after interacting with SoxCD. The stability of the complex (SoxYZCD) after simulation was also observed through the electrostatic surface potential values. These evaluations were rationalized via biostatistics. This aids SoxCD for recycling SoxY along with thiosulphate, which remains interconnected by four H-bonds with SoxY. Therefore, this novel exploration is endowed with the detailed molecular viewpoint for maintaining the sulphur cycle (globally) including the ocean belts.","PeriodicalId":15261,"journal":{"name":"Journal of Biophysics","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84747286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Coupled Phase-Temperature Model for Dynamics of Transient Neuronal Signal in Mammals Cold Receptor 哺乳动物冷感受器瞬态神经元信号动力学的相温耦合模型

Journal of Biophysics Pub Date : 2016-09-28 DOI: 10.1155/2016/2754249

Firman Ahmad Kirana, H. Alatas, Irzaman Husein

引用次数: 2

Data Acquisition System for In Situ Monitoring of Chemoelectrical Potential in Living Plant Fuel Cells 植物燃料电池化学电势原位监测数据采集系统

Journal of Biophysics Pub Date : 2016-08-30 DOI: 10.1155/2016/6108056

F. Chee, Cheng-Ann Chen, Jackson Hian Wui Chang, Ying Ying Choo, J. Dayou

引用次数: 4

Physical Non-Contact Communication between Microscopic Aquatic Species: Novel Experimental Evidences for an Interspecies Information Exchange 微观水生物种之间的物理非接触交流:物种间信息交换的新实验证据

Journal of Biophysics Pub Date : 2016-03-02 DOI: 10.1155/2016/7406356

D. Fels

引用次数: 5

Self-Optimized Biological Channels in Facilitating the Transmembrane Movement of Charged Molecules 促进带电分子跨膜运动的自优化生物通道

Journal of Biophysics Pub Date : 2016-01-29 DOI: 10.1155/2016/1657679

V. T. N. Huyen, Le Bin Ho, V. Lap, V. L. Nguyen

{"title":"Self-Optimized Biological Channels in Facilitating the Transmembrane Movement of Charged Molecules","authors":"V. T. N. Huyen, Le Bin Ho, V. Lap, V. L. Nguyen","doi":"10.1155/2016/1657679","DOIUrl":"https://doi.org/10.1155/2016/1657679","url":null,"abstract":"We consider an anisotropically two-dimensional diffusion of a charged molecule (particle) through a large biological channel under an external voltage. The channel is modeled as a cylinder of three structure parameters: radius, length, and surface density of negative charges located at the channel interior-lining. These charges induce inside the channel a potential that plays a key role in controlling the particle current through the channel. It was shown that to facilitate the transmembrane particle movement the channel should be reasonably self-optimized so that its potential coincides with the resonant one, resulting in a large particle current across the channel. Observed facilitation appears to be an intrinsic property of biological channels, regardless of the external voltage or the particle concentration gradient. This facilitation is very selective in the sense that a channel of definite structure parameters can facilitate the transmembrane movement of only particles of proper valence at corresponding temperatures. Calculations also show that the modeled channel is nonohmic with the ion conductance which exhibits a resonance at the same channel potential as that identified in the current.","PeriodicalId":15261,"journal":{"name":"Journal of Biophysics","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78739322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficiency Enhancement of Cocktail Dye of Ixora coccinea and Tradescantia spathacea in DSSC 鸡尾草和鸡翅草鸡尾酒染料在DSSC中的增效作用

Journal of Biophysics Pub Date : 2015-12-17 DOI: 10.1155/2015/582091

Zularif Zolkepli, Andery Lim, P. Ekanayake, K. Tennakoon

{"title":"Efficiency Enhancement of Cocktail Dye of Ixora coccinea and Tradescantia spathacea in DSSC","authors":"Zularif Zolkepli, Andery Lim, P. Ekanayake, K. Tennakoon","doi":"10.1155/2015/582091","DOIUrl":"https://doi.org/10.1155/2015/582091","url":null,"abstract":"The use of anthocyanin dyes extracted from epidermal leaves of Tradescantia spathacea (Trant) and petals of Ixora coccinea (IX) was evaluated in the application of dye-sensitized solar cells (DSSCs). Subsequently, cocktail anthocyanin dyes from these dyes were prepared and how they enhanced the cell's overall performance was assessed using five different volume-to-volume ratios. Cocktail dyes absorbed a wider range of light in the visible region, thus increasing the cell efficiencies of the cocktail dyes when compared to the DSSC sensitized by individual dyes. The surface charge (zeta-potential), average size of aggregated anthocyanin molecules (zetasizer), and anthocyanin stability in different storage temperatures were analyzed and recorded. Lower size of aggregated dye molecules as revealed from the cocktail dyes ensured better adsorption onto the TiO2 film. Tradescantia/Ixora pigments mixed in 1 : 4 ratio showed the highest cell efficiency of η = 0.80%, under the irradiance of 100 mW cm−2, with a short-circuit current density 4.185 mA/cm2, open-circuit voltage of 0.346 V, and fill factor of 0.499. It was found that the desired storage temperature for these cocktail dyes to be stable over time was −20°C, in which the anthocyanin half-life was about approximately 1727 days.","PeriodicalId":15261,"journal":{"name":"Journal of Biophysics","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83488750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Flexural Stiffness of Myosin Va Subdomains as Measured from Tethered Particle Motion 从栓系粒子运动测量肌球蛋白Va亚域的弯曲刚度

Journal of Biophysics Pub Date : 2015-11-30 DOI: 10.1155/2015/465693

A. Michalek, G. Kennedy, D. Warshaw, M. Y. Ali

{"title":"Flexural Stiffness of Myosin Va Subdomains as Measured from Tethered Particle Motion","authors":"A. Michalek, G. Kennedy, D. Warshaw, M. Y. Ali","doi":"10.1155/2015/465693","DOIUrl":"https://doi.org/10.1155/2015/465693","url":null,"abstract":"Myosin Va (MyoVa) is a processive molecular motor involved in intracellular cargo transport on the actin cytoskeleton. The motor's processivity and ability to navigate actin intersections are believed to be governed by the stiffness of various parts of the motor's structure. Specifically, changes in calcium may regulate motor processivity by altering the motor's lever arm stiffness and thus its interhead communication. In order to measure the flexural stiffness of MyoVa subdomains, we use tethered particle microscopy, which relates the Brownian motion of fluorescent quantum dots, which are attached to various single- and double-headed MyoVa constructs bound to actin in rigor, to the motor's flexural stiffness. Based on these measurements, the MyoVa lever arm and coiled-coil rod domain have comparable flexural stiffness (0.034 pN/nm). Upon addition of calcium, the lever arm stiffness is reduced 40% as a result of calmodulins potentially dissociating from the lever arm. In addition, the flexural stiffness of the full-length MyoVa construct is an order of magnitude less stiff than both a single lever arm and the coiled-coil rod. This suggests that the MyoVa lever arm-rod junction provides a flexible hinge that would allow the motor to maneuver cargo through the complex intracellular actin network.","PeriodicalId":15261,"journal":{"name":"Journal of Biophysics","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88162794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Review of Nuclear Microscopy Techniques: An Approach for Nondestructive Trace Elemental Analysis and Mapping of Biological Materials 核显微技术:一种无损痕量元素分析和生物材料制图的方法

Journal of Biophysics Pub Date : 2015-11-18 DOI: 10.1155/2015/740751

Stephen Juma Mulware

引用次数: 18