2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

{"title":"Anaerobic fat transfers and emulsifiers for autologous fat grafting","authors":"N. I. Khramtsova, S. Plaksin, A. Sotskov, D. N. Ponomarev","doi":"10.1109/MeMeA49120.2020.9137181","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137181","url":null,"abstract":"Autologous fat grafting is one of the most popular procedures in modern surgery. Adipose tissue, harvested by lipectomy, consists of two main fractions: fat cells, which are used in volumization, and stromal vascular fraction, which is the main source of stem cells and growth factors. In this study we analyzed the devices, such as fat filters and emulsifiers, and the results of fat processing.Initially fat harvested by lipectomy is not homogeneous, but consists of conglomerates of adipocytes. The usage of fat filters improves the rheology of fat by reducing the size of them. The fat emulsifiers purify fat from the connective tissue, leaving it on the grid.In this study, the number of destroyed adipocytes increased, and the number of viable fibroblast-like cells decreased significantly with each passage through the 1.4 mm and 1.2 mm filters.Each passage through a nanofilter with a mesh diameter of 0.5 mm reduced the number of viable fibroblast-like cells. With a decrease in the number of passages, the desired result is preserved: fibroblast-like cells remain viable, with a minimal number of adipocytes remaining. When the filter is changed and the cell diameter is reduced, adipocytes are destroyed to a significantly greater extent, and fibroblast-like cells do not suffer. The use of 1-3 passages through a nanofilter keeps viable up to 16-20% of fibroblast-like cells, while the use of a nanofilter with a smallest diameter of 0.15 mm destroys the fat cells already after 3 passages.The choice of filter type should be based on the desired result. To obtain the viable adipocytes while maintaining fibroblast-like cells, it is advisable to use untreated fat or a filter with a maximum diameter of, for example, 1.4 mm. It is advisable to use a 1.2 mm filter to maintain the same number of fibroblast-like cells, but less number of adipocytes. The use of nanofilters is recommend to use when it is necessary to disconnect adipocytes as much as possible, or destroy them, preserving only stromal cells.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130854059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of position repeatability of surgical EM tracking systems employing magnetic field model","authors":"M. Ragolia, F. Attivissimo, A. Nisio, A. Lanzolla","doi":"10.1109/MeMeA49120.2020.9137161","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137161","url":null,"abstract":"Position repeatability is a very important issue in navigation systems, especially in medical applications, where the precision of about 1-2 mm is required in many procedures. This paper proposes an effective procedure for assessing the position repeatability error of electromagnetic tracking systems (EMTSs) for surgical navigation, by using a model of the magnetic field based on magnetic dipole approximation of the transmitting coils. The proposed method allows to obtain quite accurate estimation of position repeatability errors even if the system parameters are affected by uncertainty.The new approach is applied on a novel EMTS prototype, developed to improve the state-of-the-art of current commercial systems. The obtained results are compared with the ones obtained in previous experimental tests without using magnetic field model and with the need to have more measurement data.Finally, the accuracy of the proposed method is evaluated for different orientations of the sensor","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131703521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rehabilitation Outcome in Patients undergone Hip or Knee Replacement Surgery using Inertial Technology for Gait Analysis","authors":"G. Pagano, G. D'Addio, Maurizio De Campi, L. Donisi, A. Biancardi, M. Cesarelli","doi":"10.1109/MeMeA49120.2020.9137125","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137125","url":null,"abstract":"Modern biomedical technologies are increasingly spreading to overcome the limitation based on the use of qualitative methods such as clinical scales, in fact in the clinical practice wearable inertial systems for gait analysis are spreading to support the clinical-therapeutic decision and to control the follow-up of patients. The purpose of this study is to investigate the rehabilitation outcome of patients under examination in terms of spatiotemporal parameters using the Stand and Walk test. A population-based sample of 30 post-surgical patients undergone hip or knee replacement surgery was studied; gender, age, weight, drug therapy and physiotherapy treatment were recorded. Data were calculated using a wearable inertial system for gait analysis: Opal System by APDM and analyzed using ANOVA test. Overall, ANOVA test between admission phase and discharge one, it emerges that there is a significant statistical difference on six spatiotemporal parameters related to gait, turning and anticipatory postural adjustments (APA). Study results suggest that there is an improvement in mobility of patients hospitalized at the Operating Rehabilitation and Functional Recovery Unit of ICS Maugeri Institute of Care and Scientific Research of Bari (Italy) after only a month of rehabilitation treatment. This result suggest the importance of rehabilitation and of the rehabilitation institutes in the follow-up of post-surgical patients.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125437023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impedance Measurement Exploited for Anaphylaxis Prediction in Casein Allergic Children","authors":"S. Barni, M. Mugnaini, A. Fort, F. Mori, M. Tani, V. Vignoli, Elia Landi, Riccardo Moretti, T. Addabbo","doi":"10.1109/MeMeA49120.2020.9137358","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137358","url":null,"abstract":"In this manuscript the authors present some impedance measurement results on a representative number of cases taken among children which are affected by different casein allergy severity degrees. In particular four groups of highly allergic, medium allergic and low allergic children have been identified together with controls and compared in order to verify if discrimination among healthy and affected children was possible. The measurement results provide signature components to discriminate between allergic children and components. Such features have been then used, concerning the time graphs to feed a Fuzzy classifier in the effort to prove that a cut-off threshold can be experimentally identified.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"266 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122985124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telemedicine DSS-AI Multi Level Platform for Monoclonal Gammopathy Assistance","authors":"A. Massaro, A. Galiano, Domenico Scarafile, A. Vacca, Antonella Frassanito, A. Melaccio, Antonio Giovanni Solimando, R. Ria, G. Calamita, Michela Bonomo, Francesca Vacca, A. Gallone, F. Attivissimo","doi":"10.1109/MeMeA49120.2020.9137224","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137224","url":null,"abstract":"The proposed work describes preliminary results of a research project based on the realization of a Decision Support System -DSS- platform embedding medical and artificial intelligence -AI- algorithms. Specifically the telemedicine platform is suitable for the optimization of assistance processes of patients affected by Monoclonal Gammopaty. The results are related to the whole design of the platform implementing a DSS based on a multi-level decision making process. Starting from the main architecture specifications, is formulated a flowchart based on different alerting levels of patient risk including artificial intelligence -AI- decision supporting facilities. Finally, the perspectives of the performed research are discussed.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122635496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, realization and experimental characterisation of a controllable-compliance joint of a robotic exoskeleton for assist-as-needed rehabilitation","authors":"A. Capace, L. Randazzini, C. Cosentino, M. Romano, A. Merola, Francesco Amato","doi":"10.1109/MeMeA49120.2020.9137142","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137142","url":null,"abstract":"Nowadays rehabilitation robotics has increasingly widespread applications into the biomedical field. One of the most promising strategies for the control of rehabilitation robots is the \"assist-as-needed\" approach, which is conceived to adapt the level of assistance of the robot on the basis of the physical characteristics and ability of the patient undergoing the robotic therapy. Within the framework of \"assist-as-needed\" control, the optimal adaptation of the robot performance can be achieved through some strategies that exploit the intrinsic compliance of soft actuators to regulate the interaction between the robot and the patient.This paper presents the current steps of the mechatronic design of a biorobotic joint with controllable compliance, towards the direction of the realization of a wearable and soft exoskeleton for \"assist-as-needed\" rehabilitation. The biorobotic joint is actuated by pneumatic artificial muscles (PAMs) that are soft actuators with variable stiffness.As result of the process of design and validation of the mechanism of regulation of the joint compliance, some experimental tests, which involve the measurements of pressure and force of the used PAMs, have been performed in order to characterize the performance of the mechanism of regulation influenced by the nonlinear and hysteretic response of the PAMs.The regulation mechanism enables the implementation of a novel and effective control strategy guaranteeing safe and biomimetic performance for the optimal regulation of the mechanical compliance of biorobotic joints over the full ranges of pressure and motion of the joint. The proposed control law overcomes some limiting assumptions taken in existing strategies of control of the pressure of the PAMs involved into the regulation of the mechanical compliance of rehabilitation robots actuated by pneumatic muscles.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128128178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The CT stimulation induced abnormal response in subjects with ASD: EEG study","authors":"G. Portnova, I. V. Skorokhodov, A. Varlamov, I. Shpitsberg","doi":"10.1109/MeMeA49120.2020.9137318","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137318","url":null,"abstract":"The research is a pilot electroencephalographic study of C-tactile (CT) perception in persons with autism, as abnormalities of such perception may contribute to communicative deficit in this group. Three types of stimulation were performed: slow (2-3 cm/sec) stroking with a soft brush, a hard brush, and an artificial peacock feather. The stimulation was performed in two regions: back of a forearm, rich in CT afferents, and palm, where their density is lower. Young individuals with ASD and their typically developing peers participated in the study. Unlike the controls, the ASD participants did not show pleasant behavior reaction and fractal dimension increase. The ASD participants also showed Hjorth complexity and alpha power increase accompanying negative affect, which was uncommon for the controls.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128146976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global lower limb muscle coactivation during walking in trans-femoral and trans-tibial amputees","authors":"A. Tatarelli, M. Serrao, T. Varrecchia, L. Fiori, A. Silvetti, C. D. Marchis, Simone Ranaldi, F. Draicchio, S. Conforto, A. Ranavolo","doi":"10.1109/MeMeA49120.2020.9137121","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137121","url":null,"abstract":"The aim of this work was to analyze the global coactivation (mechanism that regulates the simultaneous activity of antagonist muscles around the same joint) of the sound limb in people with unilateral trans-femoral and transtibial amputation in order to understand how the nervous system manages different levels of amputation and different types of prostheses. To achieve this aim, we calculated the global coactivation of 12 muscles using a time-varying multi-muscle co-activation function in 25 subjects with unilateral trans-femoral amputation (7, 12 and 6 with mechanical, electronic and bionic prosthesis respectively), in 7 subjects with trans-tibial amputation and in 20 healthy subjects representing the control group. The results highlight that, both trans-tibial and trans-femoral amputees show a characteristic double-peak shape as in healthy subjects although the second peak, in particular in subjects with trans-femoral amputation, appears to be slightly delayed with respect to the one that characterizes the control subjects. Furthermore, there is greater variability for both samples of amputees, with respect to the control subjects. On the other hand, TFA patients adopt similar strategies regardless of the kind of prosthesis. These results might indicate that the CNS has to manage, through the sound limb, a higher complexity due to double prosthetic joint of the amputated limb during the transfer to it of the body weight and all the control strategies that the patient adopts in response to the reorganization of the sensorimotor system as a consequence of the amputation. These findings suggest that the global lower limb coactivation behavior could be a useful measure of the motor control strategy, limb stiffness, postural stability in subjects with lower limb amputation.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133545485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal force evaluation for isotonic fatigue characterization in mouse Tibialis Anterior muscle","authors":"Flavia Forconi, F. Martelli, S. Pisu, A. Musarò, E. Rizzuto, Z. Prete","doi":"10.1109/MeMeA49120.2020.9137316","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137316","url":null,"abstract":"Skeletal muscle fatigue is most often studied as a response to repeated stimulations in isometric conditions and it is usually quantified as the progressive loss of force generating capability over time. However, physical dynamic activity is based on the shortening of skeletal muscles. Therefore, the condition that best mimics body movements is the isotonic one, in which muscle is allowed to shorten against a constant load. In the literature, the isotonic fatigue test is performed allowing the muscle to lift a load corresponding to one-third of the maximal isometric force (reference optimal force), as best representative of the force at which the tissue develops its maximum power. The goal of this study was to devise a new testing protocol in which each muscle was tested for isotonic fatigue by shortening against its own optimal force, i.e. the force at which it really developed the maximum power. Our hypothesis was that testing all the muscle at a standard reference value would introduce significant errors in the parameters associated to muscle fatigue and in their variance. The proposed protocol was based on the real-time measurement of the maximum power a muscle was able to generate through the application of the after-load technique and a mathematical interpolation to the Hill's equation, that therefore allowed to determine the experimental optimal force to be applied during the fatigue test. Experimental results showed that the muscles tested with the experimental optimal force had a fatigue time significantly lower than the control muscles tested with the reference optimal force. A decrease, even if not statistically significant, was also measured for the power and work generated during the fatigue test. Of note, for all these parameters a huge decrease in the measurement variance was reported, confirming that a precise assessment of the muscle experimental optimal force was needed to increase the accuracy of the measurements. On the other hand, the application of the protocol proposed in this work required an increase in the test duration, due to the application of the after-load technique, and a real time measurement of the power generated by the tissue.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132234067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Reading Movement from EOG Signals","authors":"F. Latifoğlu, Ramis Ileri, E. Demirci, Çiğdem Gülüzar Altıntop","doi":"10.1109/MeMeA49120.2020.9137290","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137290","url":null,"abstract":"In this paper, it is aimed to analysis of Electrooculography (EOG) signals recorded during the back to eye movement (retrieving words/re-reading) and skipping lines while reading. Two situations are characterized by large amplitude fluctuations in EOG signals. For this aim, EOG signals were recorded simultaneously while reading a text from 10 volunteers and changes in EOG signals caused by jumping a bottom line and back movements as reading were analyzed. The classification of these signals may allow the development of a new method for early and rapid diagnosis of various reading disorders (for example dyslexia). This study consists of two main processes; feature extraction and classification. Firstly, two features were determined from the recorded EOG signals for determination of retrieving words/re-reading from EOG signal. Then these signals were applied as input to various classifiers. The classifier performances were evaluated by calculating accuracy, sensitivity, specificity, precision and F measure. Overall classification results were obtained with high performance from all classifiers, and the highest accuracy of the classifiers used was 98% for each of the Random Forest and k-NN classifiers. The results show that this proposed method has an important performance for classification of eye movements from EOG signals.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114724335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}