ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy最新文献

{"title":"28 Increasing the diagnostic yield of the 100,000 genomes project for participants with congenital heart disease","authors":"Stephanie L. Baross, Simon G. Williams, Kathryn E. Hentges, B. Keavney","doi":"10.1136/heartjnl-2022-bcs.28","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.28","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"123 15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116976047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"10 Disease penetrance in asymptomatic carriers of familial cardiomyopathy variants","authors":"A. Mahmood, D. Morris-Rosendahl, M. Edwards, Andrew Fleming, T. Homfray, Samantha Mason, Ellie Quinn, James Ware, J. Baksi, S. Prasad, A. Pantazis, B. Halliday","doi":"10.1136/heartjnl-2022-bcs.10","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.10","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122705520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2 Prevalence and diagnostic significance of novel 12-lead ecg patterns following COVID-19 infection in elite soccer players","authors":"R. Bhatia, A. Malhotra, H. MacLachlan, S. Gati, S. Marwaha, S. Al-Turaihi, P. Catterson, Sean Carmody, N. Chatrath, R. Cooper, H. Dhutia, S. Fyyaz, Ravi Gill, Chris Jones, Dimitrios Kalogiannidis, A. Kenny, Tamin Khanbhai, A. Ladak, C. Miles, Chris Mogekwu, Gary O’Driscoll, Paulo Angelo Bulleros, Z. Fanton, R. Osborne, D. Oxborough, John Quartermain, Kashif Quazi, D. Rakhit, M. Sala, A. Varnava, M. Esteban, G. Finocchiaro, A. Kasiakogias, S. Khoury, Shoaib Amaan, S. Basu, Rishi Dand, J. O’Shea, M. Papadakis, Sanjay Sharma","doi":"10.1136/heartjnl-2022-bcs.2","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.2","url":null,"abstract":"2 Table 1Clinical Characteristics and CMR and 31P-MRS findings HV n=15 Isolated AS n=63 Diabetes and AS n=25 P value Age, y 71±4 71±12 72±7 0.73 Female, n (%) 6(40) 7(28) 25(40) 0.3 BMI, kg/m2 26±2* 27±4€ 31±4 <0.0001 Systolic BP, mmHg 136±9 132±17 131±20 0.44 HbA1c, mmol/mol 37±3* 37±4€ 56±14 <0.0001 NT- proBNP, ng/L 67[21-112] * 1411[629-2194]† 1376[390-2362] <0.0001 Euro Score II - 1.13 1.14 0.27 Rockwood Score - 2.15 2.22 0.23 CARDIAC STRUCTURAL AND FUNCTIONAL CHANGES LV end-diastolic volume indexed to BSA, mL/m2 78±15 80±22 84±21 0.53 LV end-systolic volume indexed to BSA, ml/m2 28±6 32±22 35±19 0.24 LV mass, g 102±25* 147±41† 164±59 0.0003 LV mass to LV end-diastolic volume, g/mL 0.66±0.11* 0.99±0.26† 0.96±0.25 <0.0001 LV stroke volume, ml 95±22 94±22 100±20 0.42 LV ejection fraction,% 64±3 64±12 60±12 0.25 LV maximal wall thickness, mm 10±1* 14±3† 14±3 <0.0001 RV end-diastolic volume indexed to BSA, mL/m2 83±12 79±18 78±20 0.36 RV end-systolic volume indexed to BSA, ml/m2 32±7 37±14 37±16 0.6 RV stroke volume, ml 97±17† 82±20 84±22 0.03 RV ejection fraction,% 62±5* 55±9† 54±10 0.01 LA biplane end-systolic volumes, mL 72±20 95±50 100±44 0.16 Biplane LA EF,% 59±11* 45±17 39±19 0.008 Global longitudinal strain, (-),% 16±4* 13±4† 11±4 0.001 Peak systolic circumferential strain, (-),% 21±2 1 ±5 18±5 0.11 Peak longitudinal diastolic strain rate, s-1 0.79±0.2 0.83±0.3 0.65±0.2€ 0.04 Mean native T1, (ms) 1209±79 1232±88 1262±84 0.16 Extra cellular volume, (%) 24±3 24±2 25±4 0.54 LGE, (%) - 3.1±2 3.4±4 0.85 MYOCARDIAL ENERGETICS AND PERFUSION PCr/ATP ratio 2.17±0.5* 1.74±0.4† 1.39±0.25€ <0.0001 Increase in RPP,% 25 23 25 0.5 Stress MBF, ml/min/g 2.14±0.66* 1.68±0.6† 1.24±0.3€ <0.0001 Rest MBF, ml/min/g 0.66±0.11 0.73±0.2 0.68±0.22 0.4 MPR 3.83±1.8* 2.4±0.78† 1.78±0.47€ <0.0001 € signifies p<0.05 between AS DM and AS Control, * signifies p<0.05 between AS DM and HV, † signifies p≤0.05 between AS Control and HV.Values are mean ±standard deviations or percentages. BSA indicates body surface area;LV, Left ventricle;RV, right ventricle;DM, type 2 diabetes mellitus;HCM, hypertrophic cardiomyopathy;LV, left ventricular;LA, left atrial;LA EF, left atrial ejection fraction;PCr, phosphocreatine;ATP, adenosine tri-phosphate;RPP, rate pressure product;MBF, myocardial blood flow;MPR, myocardial perfusion reserve. 2 Figure 1Cumulative incidence of the clinical events after valve replacement (AVR) is shown in the top row. Differences in myocardial PCr/ATP ratio, global stress myocardial blood flow and global longitudinal strain between healthy volunteers, patients with isolated severe AS and patients with severe AS and DM before the AVR in PCr/ATP ratio;global stress myocardial blood flow (ml/min/g) and global longitudinal strain are shown in the middle row. Changes in energetics, stress MBF and GLS after AVR are shown in the bottom row.[Figure omitted. See PDF]Conclusion3% of elite soccer players demonstrated novel ECG changes post COVID-19 infection, of which a","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121137610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"19 Signal averaged ecg changes in hypertrophic cardiomyopathy with obstructive sleep apnoea","authors":"S. Karim, Shreyas Venkataraman, A. Chahal, Virend Somers","doi":"10.1136/heartjnl-2022-bcs.19","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.19","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127386080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"31 Arrhythmia as a herald sign for cardiac lymphoma in a young and immunocompetent patient","authors":"Thomas Wardill, Sadaf Diamondali, Chris Steadman","doi":"10.1136/heartjnl-2022-bcs.31","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.31","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117127265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"27 Utilisation of genetic testing in an adult congenital heart disease clinic","authors":"S. Raza, D. Cullington, Matthew J. Daniels","doi":"10.1136/heartjnl-2022-bcs.27","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.27","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123281305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"20 Predictors of permanent pacemaker insertion after mitral valve replaement","authors":"J. Malik, Hamza Ghauri, Raafe Iqbal","doi":"10.1136/heartjnl-2022-bcs.20","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.20","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131705803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"1 Mitral valve abnormalities in decedents of sudden cardiac death due to hypertrophic cardiomyopathy and idiopathic left ventricular hypertrophy","authors":"R. Bhatia, S. Khoury, J. Westaby, E. Behr, M. Papadakis, Sanjay Sharma, G. Finocchiaro, M. Sheppard","doi":"10.1136/heartjnl-2022-bcs.1","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.1","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130701313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"29 Alivecor: detecting arrythmias in a single centre adult congenital population","authors":"J. W. Pennington, Katee English, Sarah Gardner","doi":"10.1136/heartjnl-2022-bcs.29","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.29","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125423881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"21 Atherosclerosis in fabry disease","authors":"A. Roy, H. Umar, Antonio Ochoa-Ferraro, A. Warfield, N. Lewis, T. Geberhiwot, R. Steeds","doi":"10.1136/heartjnl-2022-bcs.21","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-bcs.21","url":null,"abstract":"","PeriodicalId":152114,"journal":{"name":"ACHD/Valve Disease/Pericardial Disease/Cardiomyopathy","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123523554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}