Journal of Cardiovascular Electrophysiology最新文献

{"title":"Step-by-Step Approach to Phrenic Nerve Displacement.","authors":"Carli J Peters, Gregory E Supple","doi":"10.1111/jce.16617","DOIUrl":"https://doi.org/10.1111/jce.16617","url":null,"abstract":"<p><p>Phrenic nerve injury, though rare, can be a serious complication of catheter ablation leading to significant morbidity. The close proximity of the phrenic nerve to the site of origin of arrhythmias may also impact the success of catheter ablation. When the phrenic nerve is near the optimal site of ablation, several techniques have been proposed to create separation between the nerve and the epicardium, including the introduction of fluid, gas, and balloons. In this article, we present a step-by-step approach to phrenic nerve displacement to facilitate ablation, including a review of phrenic nerve anatomy, localization techniques, procedural strategies, and necessary equipment.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Power Short-Duration Temperature-Controlled Radiofrequency Ablation for the Treatment of Outflow Tract Ventricular Arrhythmias.","authors":"Dionyssios Leftheriotis, Panagiota Flevari, Konstantinos A Papathanasiou, Efstratios Karamanolis, Alexandra Gkatzia, Maria Polikandrioti, Gerasimos Filippatos","doi":"10.1111/jce.16636","DOIUrl":"10.1111/jce.16636","url":null,"abstract":"<p><strong>Introduction: </strong>The tissue temperature-controlled DiamondTemp ablation (DTA) catheter has been mainly used for atrial fibrillation ablation. We report our initial experience in using this catheter for the treatment of outflow premature ventricular contractions (PVCs) or repetitive non-sustained monomorphic ventricular tachycardias (VTs).</p><p><strong>Methods: </strong>Twenty patients were studied: 10 with right ventricular outflow tract PVCs/VTs, eight with PVCs/VTs from the aortic sinus cusps, and two with left ventricular outflow tract PVCs. The DTA parameters were adjusted to a target-temperature of 60°C with 50 W power. Ablation success was defined as the absence of clinical VT/PVCs at the end of the procedure and during the next 48 h of continuous rhythm monitoring without antiarrhythmic drugs. All patients were reevaluated 2 months after the ablation.</p><p><strong>Results: </strong>The average ablation duration was 262 (145-690) seconds and the average tissue temperature (T) was 50.4 ± 2.9°C. A mean number of 11 ± 6 lesions per case were applied. The average time of T > 50°C was 18 (12-20) seconds, that is 70% of the ablation time, and an average relative impedance drop of 13.8 ± 2.0% was recorded. No serious complications occurred, and no VT recurrence was observed until discharge and during the short follow-up period.</p><p><strong>Conclusion: </strong>This initial evaluation suggests that the DTA system reached the adjusted temperature and power targets, and it can be effectively and safely applied for the treatment of outflow tract PVCs/VTs. This performance should be further evaluated by long-term randomized controlled trials in comparison to conventional ablation catheters.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urban-Rural Differences in the Outcomes of Patients Hospitalized for Cardiac Implantable Electronic Devices Infection in the United States.","authors":"Siddharth Agarwal, Zain Ul Abideen Asad, Muhammad Bilal Munir, Justin Z Lee, Daniel C DeSimone, Christopher V DeSimone, Abhishek J Deshmukh","doi":"10.1111/jce.16637","DOIUrl":"https://doi.org/10.1111/jce.16637","url":null,"abstract":"<p><strong>Background: </strong>Cardiac implantable electronic device (CIED) infections are a serious complication associated with significant morbidity, mortality, and healthcare costs. Despite guideline recommendations for complete device removal, disparities in healthcare access and resource availability between urban and rural settings may influence patient outcomes. This study aims to evaluate rural-urban disparities in the management and outcomes of patients hospitalized with CIED infections.</p><p><strong>Methods: </strong>A retrospective cohort analysis was conducted using the National Readmissions Database (NRD) from 2016 to 2021. Patients aged ≥ 18 years hospitalized with CIED infections were identified using ICD-10 codes. Hospital location was categorized as urban or rural based on the Urban Influence Codes. Baseline characteristics, complications, and outcomes were compared using chi-square and t-tests, and a multivariable logistic regression model was employed to assess the independent association of hospital settings with transvenous lead removal (TLR) utilization.</p><p><strong>Results: </strong>A total of 288,402 patients were hospitalized for CIED infections, with 94.9% treated in urban hospitals and 5.1% in rural hospitals. Urban hospital patients had a higher prevalence of key comorbidities, including heart failure, valvular heart disease, atrial fibrillation and peripheral vascular disorders. In-hospital mortality was significantly higher in urban hospitals (6.2% vs. 4.8%, p < 0.01) likely due to higher burden of comorbidities and higher rates of acute complications such as stroke (3.1% vs. 1.8%, p < 0.01) and systemic embolism (1.4% vs. 0.7%, p < 0.01). TLR was more frequently performed in urban hospitals (20.1% vs. 9.6%, p < 0.01), with rural hospitals exhibiting 59% lower odds of receiving TLR (OR: 0.41, 95% CI: 0.36-0.47, p < 0.01). TLR was associated with reduced in-hospital mortality, 30-day mortality, and 30-day readmission rates across both hospital settings.</p><p><strong>Conclusion: </strong>Our study highlights significant rural-urban disparities in CIED infection management. Despite rural hospitals admitting patients with a lower comorbidity burden, TLR utilization was significantly lower, potentially due to limited access to specialized expertise and procedural resources. Given TLR's association with improved survival and reduced readmissions, regardless of the hospital setting, targeted interventions are needed to enhance access to specialized care in rural settings. Further research is warranted to explore strategies for bridging these disparities and optimizing CIED infection outcomes nationwide.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Extent of Pulmonary Vein Electrical Connections Predicts the Success of Stand-Alone Pulmonary Vein Isolation in Persistent Atrial Fibrillation.","authors":"Matteo Marchetti, Christelle Haddad, Adrian Luca, Mathieu Le Bloa, Cheryl Teres, Giulia Domenichini, Alessandra Pia Porretta, Claudia Herrera, Etienne Pruvot, Patrizio Pascale","doi":"10.1111/jce.16622","DOIUrl":"https://doi.org/10.1111/jce.16622","url":null,"abstract":"<p><strong>Background: </strong>Identification of persistent AF (PsAF) patients who may be cured with stand-alone pulmonary vein isolation (PVI) would allow more efficient ablation strategies. Intuitively, the benefit of PVI is expected to be lower when PVs are poorly connected, but this assumption has never been tested.</p><p><strong>Objective: </strong>Evaluate whether the circumferential extent of PV connections assessed pre-ablation predicts the success rate of PVI.</p><p><strong>Methods: </strong>Consecutive patients with PsAF undergoing first ablation with stand-alone PVI were included. The extent of PV electrical connection was assessed using a circular mapping catheter and graded as limited, moderate, or extensive, according to tertiles of the mean numbers of bipoles recording PV potentials along the circumference of each vein.</p><p><strong>Results: </strong>One hundred and forty-eight patients were included (age 64 ± 9.7 years, PsAF duration 7.3 ± 7 months). After a mean follow-up of 38.6 ± 7.8 months, freedom from arrhythmia recurrence after last PVI was significantly lower in patients with limited (38.6%), compared to moderate, and extensive PV connections (69.7% and 69%, respectively; p = 0.002). While redo PVI procedures did not significantly affect final ablation outcomes in patients with limited PV connections, a significant incremental arrhythmia-free survival gain was observed with increasing extent of PV connections (p < 0.01).</p><p><strong>Conclusions: </strong>The circumferential extent of PV connections is correlated to the success rate of PVI in patients with PsAF and may be a marker of the contribution of PVs to AF. The finding of limited PV connections may be used to select patients who may benefit from first-line adjunctive ablation.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial Fibrillation as a Predictor of Age-Related Macular Degeneration.","authors":"Kaden T Bunch, Heidi T May, Kirk U Knowlton, Tami L Bair, J Brent Muhlestein, Jeffrey L Anderson, Ravi Ranjan, Benjamin A Steinberg, T Jared Bunch","doi":"10.1111/jce.16627","DOIUrl":"https://doi.org/10.1111/jce.16627","url":null,"abstract":"<p><strong>Background: </strong>Aging of the population has resulted in more patients living with atrial fibrillation (AF) and age-related macular degeneration (AMD). AF is associated with macro- and micro-thromboembolism, microvascular dysfunction, and system inflammation. Organ systems sensitive to the long-term systemic and vascular disease associations of AF will likely develop dysfunction over time. There is also an increase in age-related macular degeneration (AMD), which shares many pathophysiologic risk factors of AF. We hypothesized that AF will increase the risk of AMD.</p><p><strong>Methods: </strong>A total of 38 746 consecutive patients from the large ongoing prospective angiography INSPIRE Study database without a history of AMD were evaluated for the development of AMD. Long-term incidence of AMD was assessed at 1 and 5 years and at last follow-up to determine its association with AF.</p><p><strong>Results: </strong>Over a mean follow-up of 2159.4 ± 1851.7 days, 11 787 (30.4%) had or developed AF. Patients with AF were older (67.7 ± 12.2 vs. 57.5 ± 15.5 years, p < 0.0001), and had higher rates of hypertension (50.0% vs. 44.0%, p < 0.0001), renal failure (1.7% vs. 1.1%, p < 0.0001), stroke (4.6% vs. 3.1%, p < 0.0001), and heart failure (27.3% vs. 11.5%, p < 0.0001). AF patients were more likely to be treated with a statin, ACE/ARB, diuretic, and warfarin. The overall incidence of AMD over the follow-up period was higher in patients with AF (2.1% vs. 1.2%, p < 0.0001). Compared with no AF, the risk of AMD in patients with AF was increased at 1 year (hazard ratio [HR] = 1.92 [1.26-2.93], p = 0.003), 5 years (HR = 1.83 [1.46-2.29], p < 0.0001), and long-term (1.80 [1.52-2.12], p < 0.0001). The association of AF with AMD was attenuated after adjustment by baseline characteristics, comorbidities, and medications. All AMD risks were mitigated in multivariable modeling that included baseline characteristics (i.e., CHA2DS2-Vasc) and drug therapies for AF.</p><p><strong>Conclusion: </strong>Patients with AF are at elevated risk of developing AMD that increases over time when compared to patients without AF. In this cohort of patients, the risk of AMD is due to risk factors that drive the presence of AF itself and its progression. Comprehensive treatment of AF that focuses on its underlying risk factors, including dynamic reassessment of risk factors during follow-up, may impact risk of AMD in patients with AF.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial Fibrillation (AF) and Heart Failure With Preserved Ejection Fraction (HFpEF): Advances and Challenges.","authors":"Sanjeev Saksena, April Slee, Ranghadham Nagarakanti, Atul Prakash","doi":"10.1111/jce.16625","DOIUrl":"https://doi.org/10.1111/jce.16625","url":null,"abstract":"<p><p>This state-of-the-art review is based on the Philippe Coumel Lecture in 2024 (Figure 1). It highlights the confluence of two major cardiovascular epidemics, atrial fibrillation and heart failure, with preserved ejection fraction. In these conditions, advances in electrophysiology and heart failure physiology are intertwined and are integrated in this review. This constellation of disease states has its own unique epidemiologic features, pathophysiology, experimental and clinical mechanisms; and an increasing knowledge base with respect to clinical presentation, prognostic implications, and therapeutic options from pharmacologic advances and non-pharmacologic interventions. Major advances, continuing challenges, and future directions in this condition are described in this rapidly evolving field of scientific endeavor.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Neglected Parameter: Tricuspidal E Wave Deceleration Time as Predictor of Atrioventricular Synchrony in VDD Leadless Pacemakers.","authors":"Mattia Strazzanti, Caterina Maffeis, Luca Tomasi, Sofia Capocci, Bruna Bolzan, Elena Franchi, Flavio Luciano Ribichini, Giacomo Mugnai","doi":"10.1111/jce.16613","DOIUrl":"https://doi.org/10.1111/jce.16613","url":null,"abstract":"<p><p>Leadless pacemakers as the Medtronic Micra AV, have improved cardiac pacing by reducing complications associated with traditional systems. However, achieving high atrioventricular synchrony (AVS) remains a challenge, especially in patients with a high pacing burden. This prospective study enrolled 30 patients to assess the role of echocardiographic parameters in predicting AVS postimplantation. AVS was evaluated via 24-h Holter monitoring, with a median AVS of 67.9% ± 9.6%. Right atrial function, particularly the tricuspidal E wave deceleration time, emerged as the only independent predictor of AVS (p = 0.03), with an AUC of 0.77. These findings suggest that pre-implantation echocardiographic assessment of right atrial parameters could aid in selecting patients who would benefit most from Micra AV. Further studies with larger cohorts and extended follow-ups are warranted.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Octaspline Multielectrode Catheter and Unipolar Reference Location for Premature Ventricular Contraction Ablation.","authors":"Pedro A Sousa, Carolina Saleiro, Sérgio Barra, Inês Fonseca, Luís Elvas, John Silberbauer, Lino Gonçalves","doi":"10.1111/jce.16618","DOIUrl":"https://doi.org/10.1111/jce.16618","url":null,"abstract":"<p><strong>Background: </strong>An accurate local activation time (LAT) map is essential during premature ventricular contraction (PVC) ablation. The aim of this study was to evaluate whether the use of a novel octaspline multielectrode catheter, with and without the use of a catheter-embedded unipolar reference, improves LAT mapping during PVC ablation compared to a pre-existing pentaspline mapping catheter.</p><p><strong>Methods: </strong>This study prospectively assessed 10 consecutive patients referred for PVC ablation from January to June 2023. Three 12-min LAT maps were performed in each patient using three different strategies: pentaspline catheter + unipolar reference in the inferior vena cava (IVC) versus octaspline catheter + unipolar in the IVC versus octaspline catheter + unipolar embedded in the mapping catheter. Acute procedural and midterm endpoints were assessed.</p><p><strong>Results: </strong>The use of an octaspline catheter increased the number of total LAT points (1010 ± 451 vs. 397 ± 213, p = 0.001), LAT points near the successful RF ablation site (118 ± 105 vs. 21 ± 19, p = 0.010) and electrograms (EGM) per PVC (23 ± 21 vs. 7 ± 3, p = 0.032), while reducing mapping duration (65 ± 41 EGM/min vs. 21 ± 8 EGM/min, p = 0.003). However, signal resolution was not superior to that obtained with the pentaspline catheter, with similar bipolar (p = 0.505) and unipolar (p = 0.176) voltages, an increased bipolar signal duration (p = 0.003) and a reduction in the unipolar signal duration (p = 0.013). Use of a catheter-embedded unipolar reference led to shorter unipolar signal duration (76 ± 34 ms vs. 142 ± 29 ms, p < 0.001), and provided an earlier unipolar signal deflection to QRS onset (-24 ± 16 ms vs. -19 ± 11 ms, p = 0.006) and earlier -dV/dT signal annotation (-12 ± 10 ms vs. -7 ± 9 ms, p < 0.001). This subsequently led to a shorter distance from the earliest LAT to successful RF site (p = 0.014). No significant differences between multielectrode mapping catheters were seen regarding catheter-induced ectopy rate (p = 0.703).</p><p><strong>Conclusions: </strong>The use of an octaspline catheter combined with an embedded unipolar reference may associate with faster, more detailed and accurate activation mapping in the setting of PVC ablation.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of Raw-Data Analysis When Determining the Cause of Pause Alerts Transmitted by an Implantable Loop Recorder Remote Monitoring Devices.","authors":"Moshe Rav Acha, Hana Raiz, Michael Glikson, Michael Ilan","doi":"10.1111/jce.16634","DOIUrl":"https://doi.org/10.1111/jce.16634","url":null,"abstract":"<p><strong>Introduction: </strong>Use of implantable loop recorder (ILR) for the diagnosis and documentation of cardiac arrhythmia has gained popularity during the last decade. Most ILRs are accompanied by remote monitoring (RM) devices, which allow automated daily interrogations of the ILR. These transmit arrhythmic or pause alerts to the treating clinic, enabling timely medical attention and treatment. Although ILR RM transmissions have been shown to have significant false positive alerts, a true positive alert suggesting a wrong arrhythmia diagnosis has not been shown to date.</p><p><strong>Methods and results: </strong>We revised all ILR pause transmissions arriving to our hospital device clinic during 2024, looking for pause alerts which were initially misdiagnosed. We report a case series of patients in whom a RM pause alert has been transmitted with a suspected apparent diagnosis of sinus arrest. However, when interrogating the ILR in clinic, these episodes were diagnosed as high-degree atrioventricular block (AVB) pauses, for which an urgent permanent pacemaker (PPM) might be indicated. Review of these cases revealed that in contrast with the automated RM PDF alerts, in which the figure resolution cannot be changed (and thus small P waves may be unnoticed), the raw-data episode recording on the RM web page enables one to increase the image resolution to clearly discern initially unnoticed non-conducted P waves.</p><p><strong>Conclusion: </strong>ILR RM pause alerts should always be reviewed via the raw-data RM web page or alternatively via ILR device interrogations, to achieve a sufficiently high-resolution image to assure these pauses are not due to AVB.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension and Atrial Fibrillation: Insight From Basic to Translational Science Into the Mechanisms and Management.","authors":"Bharat K Kantharia, Shuai Zhao, Dominik Linz, Jordi Heijman, Xander H T Wehrens","doi":"10.1111/jce.16632","DOIUrl":"https://doi.org/10.1111/jce.16632","url":null,"abstract":"<p><p>There is a parallel epidemic of atrial fibrillation (AF) and hypertension (HTN) occurring globally. Both AF and HTN are no longer confined to the older population. The pathophysiology of AF related to HTN is complex with many inter-related factors. Hypertension causes hypertrophy of the ventricular musculature, dilatation of atria, elevated intracardiac pressures, atrial and ventricular mechanical dysfunction, abnormal expression of ion channels, dysregulation of the renin-angiotensin-aldosterone system, and the autonomic function. The pathophysiological alterations and structural changes that occur in the atria, including architectural subcellular abnormalities fibrosis, are considered to cause atrial cardiomyopathy (atriopathy) predisposing to AF. In this review, we discuss some relevant and combined basic and translational science data related to HTN leading to atriopathy and AF and possible clinical applications in the treatment and prevention of AF in patients with HTN.</p>","PeriodicalId":15178,"journal":{"name":"Journal of Cardiovascular Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}