Y. Joly, Katherine Huerne, M. Arych, Y. Bombard, E. Dove, Palmira Granados, Chih-Hsing Ho, I. van Hoyweghen, Hannah Kim, Audrey Lebret, T. Minssen, Katharina Ó Cathaoir, A. Prince, M. Otlowski, Michael Pepper, R. Sladek, Lingqiao Song, Torsten Voight, M. Zawati, G. Dalpé
{"title":"Confronting New Issues in Genetic Discrimination","authors":"Y. Joly, Katherine Huerne, M. Arych, Y. Bombard, E. Dove, Palmira Granados, Chih-Hsing Ho, I. van Hoyweghen, Hannah Kim, Audrey Lebret, T. Minssen, Katharina Ó Cathaoir, A. Prince, M. Otlowski, Michael Pepper, R. Sladek, Lingqiao Song, Torsten Voight, M. Zawati, G. Dalpé","doi":"10.2139/ssrn.3920622","DOIUrl":"https://doi.org/10.2139/ssrn.3920622","url":null,"abstract":"Genetic discrimination (GD) is the differential or unfair profiling of an individual based on genetic data. This article summarizes the actions of the Genetic Discrimination Observatory (GDO) in addressing GD, and recent developments in GD since late 2020. It shows GD can take many forms in today’s rapidly evolving society.","PeriodicalId":150377,"journal":{"name":"Medical Ethics eJournal","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115540619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Trautman, Paul Seaborn, A. Sulkowski, D. Mayer, Robert T. Luttrell
{"title":"Cannabis at the Crossroads: A Transdisciplinary Analysis and Policy Prescription","authors":"L. Trautman, Paul Seaborn, A. Sulkowski, D. Mayer, Robert T. Luttrell","doi":"10.2139/ssrn.3541229","DOIUrl":"https://doi.org/10.2139/ssrn.3541229","url":null,"abstract":"Cannabis has returned to the mainstream in recent years after an interlude of legal prohibition and partial societal stigmatization. 2019 U.S. state-legal cannabis sales have been estimated at 13.6 billion dollars with predictions for sales to near 30 billion by 2025. The global market for cannabis products - including a range of products produced from non-psychoactive hemp - could approach hundreds of billions of dollars annually. At the same time, the legal cannabis industry faces significant challenges in the United States; legalization has been uneven, with disparities among states, and federal law continues to impose obstacles to predictability in the nationwide market for cannabis. \u0000 \u0000Conflicts between U.S. federal and state laws regarding cannabis are numerous. Federal law treats most forms of cannabis as illegal, yet 97.7 percent of the U.S. population –– located in 47 states, the District of Columbia, and 4 U.S. territories –– are living in jurisdictions where medical or recreational use of cannabis, including cannabidiol (“CBD”) oil, is now legal. \u0000 \u0000This Article takes a transdisciplinary approach and proceeds in eight parts. First, we explore the history of cannabis including its earliest uses, noting periodic prohibitions. Second, we look at applicable current U.S. federal statutes, both criminal and non-criminal. Third, we consider the legalization approaches and experiences in the states. Fourth, we look at the Canadian experience including national recreational market legalization in 2018. Fifth, we examine the ethical issues around recreational and medical marijuana use. Sixth, we describe the future outlook for cannabis businesses in terms of both market potential and regulation. Seventh, we describe Congressional proposals to change federal laws on cannabis. Eighth, we then draw upon these various perspectives to arrive at a policy prescription. And last, we conclude.","PeriodicalId":150377,"journal":{"name":"Medical Ethics eJournal","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124214944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug Prices, Dying Patients, and the Pharmaceutical Marketplace: A New Conditional Approval Pathway for Critical Unmet Medical Needs","authors":"R. Bohrer","doi":"10.2139/ssrn.3330925","DOIUrl":"https://doi.org/10.2139/ssrn.3330925","url":null,"abstract":"Prescription drugs are much in the news these days. There are two topics which appear very often; first, the very high prices of new drugs, particularly the “specialty�? drugs developed for serious diseases; and second, the time required for FDA approval in relation to the perceived need for earlier access to new therapies for critically ill patients. Much less in the news, but lurking behind both problems, is the need for better information for physicians and patients to use in making decisions about prescribing and taking drugs and for insurance companies and the government to use to structure their pharmaceutical benefits plans. This article proposes an approach to both accelerated access and drug prices that would generate the information doctors and patients need to make decisions about drugs and the information the government and private insurers need to provide appropriate access and coverage for those drugs. The new form of conditional approval proposed here would be similar to the parallel track program developed by the FDA in the 1990s, during the HIV crisis. I argue that, like parallel track, the conditional approval proposed here could be implemented by the FDA under its existing authority, allow wide access to desperately needed drugs, and would control prices while providing better information about the real safety and efficacy of new drugs for critically ill patients.","PeriodicalId":150377,"journal":{"name":"Medical Ethics eJournal","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124145460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reducing Avoidable Medication-Related Harm: What Will it Take?","authors":"E. Tetteh","doi":"10.2139/ssrn.3260474","DOIUrl":"https://doi.org/10.2139/ssrn.3260474","url":null,"abstract":"Consumption of quality-assured medicines is expected to maintain or improve population health. Yet in a number of situations, what is realized is lower health benefits or magnified safety risks. Recognizing the public health implications of safety risks or medication-related harm, and that some types of harm are avoidable, the World Health Organization has initiated the third Global Patient Safety challenge on Medication Safety. Under the term \"Medication Without Harm\", this Challenge aims to assess the scope and nature of avoidable medication-related harm, create a framework for intervention and develop national guidance and tools to support safer medication use. The global target under the Challenge is to reduce the level of severe avoidable medication-related harm by 50% over a five-year period or within the next five years. Given a higher morbidity and mortality due to medication-related harm in low-income countries, this paper evaluates what needs to be done in low-income countries in order to achieve the global target. The ideal solution advocated requires that health planners in each low-income country determine what fraction of safety risks or harm can be prevented; and the relationship between number or frequency of avoidable harm or safety risks and the resource costs of treatment or prevention. In the absence of such information, this paper discusses a number of prevention strategies that might help; arguing that the period over which avoidable medication-related harm can be reduced by 50% will depend on whether significant continuous investments in health-system strengthening are made prior to and within that period.","PeriodicalId":150377,"journal":{"name":"Medical Ethics eJournal","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115825357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Healthsouth (C): The Trial","authors":"P. Werhane, Jenny Mead, C. E. Collier","doi":"10.2139/ssrn.908774","DOIUrl":"https://doi.org/10.2139/ssrn.908774","url":null,"abstract":"In the winter of 2005, former HealthSouth CEO Richard Scrushy went on trial for fraud after he and other executives at HealthSouth, which specialized in outpatient surgery, rehabilitation, and physical therapy, were accused of inflating profits. The trial attracted a lot of attention, not only because of the size of the fraud and Scrushy's colorful personality and legendarily lavish spending habits, but also because this was the first case in which a corporate CEO was tried for violating the Sarbanes-Oxley Act, passed in 2002. The case summarizes the four-month trial, the tactics of both the defense and prosecution teams, and some of the long-term implications for companies accused or convicted of ethics violations. See also the A and B cases (UVA-E-0273 and UVA-E-0274).","PeriodicalId":150377,"journal":{"name":"Medical Ethics eJournal","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116130928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}