Journal of andrology最新文献

Penile Morphometrics and Erectile Function in Healthy Portuguese Men 葡萄牙健康男性阴茎形态计量学和勃起功能

Journal of andrology Pub Date : 2020-01-01 DOI: 10.35248/2167-0250.2020.9.204

H. Pereira

{"title":"Penile Morphometrics and Erectile Function in Healthy Portuguese Men","authors":"H. Pereira","doi":"10.35248/2167-0250.2020.9.204","DOIUrl":"https://doi.org/10.35248/2167-0250.2020.9.204","url":null,"abstract":"Objective: This study aimed to evaluate the relationship between penile morphometrics and erectile function in a sample of healthy Portuguese men. Methods: A sample of 1416 adult men with an average age of 39 years were surveyed and completed the following measures: socio-demographic questionnaire, penile morphometrics evaluation questionnaire, and the Portuguese version of the International Index of Erectile Function-5 (IIEF-5). Results: The average result for penis length was 16.75 cm (SD=2.25) and a circumference of 9.56 cm (SD=2.38). Levels of satisfaction with the morphometrics of the penis were relatively high (7.61 on a scale of 1 to 10, SD=1.87), as well as overall levels of erectile function (4.21 on a scale of 1 to 5; SD=0.61). Results showed a negative association between penis length and erectile function (r=-242; p<0.05), and positive association between the circumference and erectile function (r=0.183; p<0.05); penile length and circumcision was associated with less erectile function. Conclusion: This study provides evidence that penile morphometrics interferes with erectile function and this is an important source of information for professionals working in the male sexual health field.","PeriodicalId":15029,"journal":{"name":"Journal of andrology","volume":"9 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69988192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Sperm Quality and Seminal Biochemical Parameters in Infertile Men with and without Leukocytospermia 有和没有白细胞精症的不育男性的精子质量和精液生化参数

Journal of andrology Pub Date : 2018-01-01 DOI: 10.35248/2167-0250.18.7.197

Djordjevic D, Lalic N, Vukovic I, N. D., Perovic D, Kisic Dt, Micic S

{"title":"Sperm Quality and Seminal Biochemical Parameters in Infertile Men with and without Leukocytospermia","authors":"Djordjevic D, Lalic N, Vukovic I, N. D., Perovic D, Kisic Dt, Micic S","doi":"10.35248/2167-0250.18.7.197","DOIUrl":"https://doi.org/10.35248/2167-0250.18.7.197","url":null,"abstract":"Objective: White Blood Cells (WBC) are commonly present in almost every human semen sample, but the clinical significance of leukocytospermia, defined as more than 1 × 106/mL of WBC in seminal plasma, is not elucidated. The aim of this study was to evaluate the association of the leukocytospermia with sperm characteristics and biochemical markers of function of the male accessory glands in infertile men. Methods: One hundred and eighty-five men with fertility problems were investigated. They were composed of two groups, patients without leukocytospermia (n=115) and patients with leukocytospermia (n=70). The infertile men enrolled in the study underwent semen analysis and measurements of fructose, acid-phosphatase, zinc and γ- glutamyltranspeptidase in seminal plasma. Results: The mean age of study participants was 33.97 ± 6.45 years. The analysis of leukocyte concentration in semen has shown that 70 (37.8%) patients had leukocytospermia. Patients with leukocytospermia had significantly decreased sperm count and vitality while other sperm parameters such as seminal volume, progressive motility, morphology of pathological forms and seminal plasma pH were not affected. The levels of acid-phosphatase, fructose and γ-glutamyltranspeptidase were significantly decreased in infertile men with leukocytospermia compared to men without this condition. The levels of seminal zinc did not differ between the two groups of patients. Conclusion: Our results indicate that leukocytospermia has a significant negative effect on the standard semen parameters and biochemical compounds that reflect the function of accessory glands, prostate and seminal vesicles in particular.","PeriodicalId":15029,"journal":{"name":"Journal of andrology","volume":"7 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69987897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Influence of Semen Parameters and Malondialdehyde on Infertile Males in Iraq 精液参数及丙二醛对伊拉克不育男性的影响

Journal of andrology Pub Date : 2018-01-01 DOI: 10.35248/2167-0250.18.7.198

Newman Az, G. Hussain, Bassam Aa

引用次数: 1

Pure Egyptian Cattle Bulls Show both Individual Variation and Different Interaction with Extender in the Post-Thawing Sperm Parameters 纯埃及公牛解冻后精子参数表现出个体变异和与扩展器的不同相互作用

Journal of andrology Pub Date : 2017-11-30 DOI: 10.4172/2167-0250.1000193

A. A. Mohammed, W. Ahmed

{"title":"Pure Egyptian Cattle Bulls Show both Individual Variation and Different Interaction with Extender in the Post-Thawing Sperm Parameters","authors":"A. A. Mohammed, W. Ahmed","doi":"10.4172/2167-0250.1000193","DOIUrl":"https://doi.org/10.4172/2167-0250.1000193","url":null,"abstract":"Objectives: As very few studies were done on the freezability of pure Egyptian cattle bull sperm. So, we designed this study to evaluate the individual variations in freezability of native bull semen extended in Tris based diluent and sodium citrate-based diluent. \u0000Methods: Semen was collected by artificial vagina, examined at once in farm laboratory. Only semen samples fit the minimum parameters are extended in two extenders first the universal one (TRIS) and second modified Sodium citrate extender by adding glycerol (CU-16) which created at Cornell University to evaluate the individual bull variation and interaction between extender and bull. \u0000Results: Post-Thawing individual sperm motility, live, abnormal, acrosome integrity percentage was evaluated in addition to Hypo-Osmotic Swelling test (HOS). The highest value for motility, live abnormal and acrosome percentage were 44.00 ± 1.12, 52.25 ± 1.60, 21.25 ± 0.81 and 62.80 ± 2.58 from bull 2, 1, 3 and 2, respectively for semen extended in TRIS, and 42.25 ± 1.61, 52.00 ± 1.76, 22.15 ± 0.85 and 57.40 ± 3.07, from bull 1, 1, 4, 3, respectively for semen extended in CU-16. The results of HOS were 59.25 ± 1.76 and 55.95 ± 2.13 from bull 1 extended in TRIS and CU-16, respectively. \u0000Conclusion: A significant variation (p<0.05) in tested parameter was clear when semen extended in TRIS extender with the absence of such variation when semen extended in CU-16 except in live sperm percentage. With ignoring the extender effect a clear significant variations were detected between bulls in all tested parameters.","PeriodicalId":15029,"journal":{"name":"Journal of andrology","volume":"6 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45840881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Evaluation of Xgene (R) , a Eurycoma longifolia Extract Enriched Penis CareCream, as a Novel Vehicle in Creating Penis Consciousness and Confidence in Keeping and Maintaining Erection for Penetrative Sex Xgene（R），一种富含长叶Eurycoma提取物的阴茎护理霜，作为一种新的载体，在培养阴茎意识和信心以保持和维持勃起以进行穿透性行为方面的评估

Journal of andrology Pub Date : 2017-08-09 DOI: 10.4172/2167-0250.1000189

M. I. Tambi

{"title":"Evaluation of Xgene (R) , a Eurycoma longifolia Extract Enriched Penis CareCream, as a Novel Vehicle in Creating Penis Consciousness and Confidence in Keeping and Maintaining Erection for Penetrative Sex","authors":"M. I. Tambi","doi":"10.4172/2167-0250.1000189","DOIUrl":"https://doi.org/10.4172/2167-0250.1000189","url":null,"abstract":"Ancient Middle-Eastern medicine described the practise of massaging camel hump fat to revive dysfunctional penis. This practice was long forgotten. A cream containing a Malaysian herb, Eurycoma longifolia, known to increase cellular cGMP and cAMP, was put to a study to evaluate its efficacy strengthening and maintaining penis tumescence. 60 men were recruited.50 men were given active cream and the remaining; bland cream. The study was for two months. Each man was taught to massage the glans penis with the cream, to be done for 5 minutes, twice a day. The men filled up the SHIM and the Erection Hardness Score (EHS). All these were repeated at two weeks, one month, 6 weeks and end of study. All men completed the study, claimed the cream made their penis skin fine.4 men on bland cream and all the 50 men on active cream claimed that they get bigger and firmer erections, scoring higher SHIM Score and Erection Hardness Score. The active cream provided better grade erection and good control of ejaculation. The ancient concept of a penis caring cream to maintain healthy penis function and wellness can be a good way in ensuring healthy penis function.","PeriodicalId":15029,"journal":{"name":"Journal of andrology","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48664686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Ecto-Cyclic AMP Independent Protein Kinase-A Potent Regulator of L-type Calcium Channel and Forward Motility of Goat (Capra indicus) Epididymal Spermatozoa 外环AMP独立蛋白激酶-山羊附睾精子l型钙通道和前向运动的有效调节剂

Journal of andrology Pub Date : 2017-08-07 DOI: 10.4172/2167-0250.1000188

D. Nath, M. Shaw

{"title":"Ecto-Cyclic AMP Independent Protein Kinase-A Potent Regulator of L-type Calcium Channel and Forward Motility of Goat (Capra indicus) Epididymal Spermatozoa","authors":"D. Nath, M. Shaw","doi":"10.4172/2167-0250.1000188","DOIUrl":"https://doi.org/10.4172/2167-0250.1000188","url":null,"abstract":"Objective: Caprine (Capra indicus) spermatozoa possess a novel ecto-cAMP independent protein kinase (ecto- CIK) on their membrane surface. This enzyme showed remarkable alteration through the maturation process of spermatozoa in epididymis. We investigated the role of CIK in the regulation of forward motility of epididymal spermatozoa by controlling the intracellular level of [Ca2+]. \u0000Method: Cauda epididymal mature sperm cells were treated with CIK antibody and maximum inhibition of enzyme activity (85%) was observed at 120 minutes of exposure. To analyze the calcium uptake mechanisms cells were exposed to 45Ca2+ after treatment with CIK antibody and pretreated with different calcium channel regulators. The intracellular [Ca2+]i signal was determined fluorometrically by using fura 2-AM. The computerized spectrophotometric assay method was used to measure the percentage of forward motility. \u0000Result: It was shown that the uptake of calcium through the L-type voltage-dependent Ca2+ channels of the plasma membrane is regulated by CIK. Pretreatment of sperm cells with varapamil (20 μM), nifedipine (20 μM) significantly inhibited the increased intracellular [Ca2+]i induced by the CIK antibody. Whereas calmodulin antagonists trifluoperazine and w13 (N-(4-Aminobutyl)-5-chloro-2 naphthalenesulfonamide hydrochloride and sodium azide, a potent mitochondrial inhibitor, showed no effect on this calcium entry. The treatment with ca ionophore A123187 of the CIK antibody treated cells showed channel inhibitor insensitive increase of calcium uptake. It was observed that verapamil (20 μM) has significant role in decreasing (~50%) forward motility of CIK-antibody treated spermatozoa. \u0000Conclusion: We concluded that CIK is an important regulator of forward motility in epididymal spermatozoa and the regulation may be activated partly by the intracellular [Ca2+]i level the extent of which is functionally imparted by the voltage gated L type calcium channel.","PeriodicalId":15029,"journal":{"name":"Journal of andrology","volume":" ","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48664142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Annexin V based Sperm Selection in Assisted Reproduction 基于膜联蛋白V的精子选择在辅助生殖中的应用

Journal of andrology Pub Date : 2017-07-07 DOI: 10.4172/2167-0250.1000182

Teijeiro Juan Manuel, Munuce María José, Caille Adriana María, Zumoffen Carlos, M. Estela

引用次数: 8

Stress and Cell Death in Testicular Cells 应激与睾丸细胞死亡

Journal of andrology Pub Date : 2017-06-10 DOI: 10.4172/2167-0250.1000183

Juárez-Rojas, Lizbeth, Casillas Fahiel, Retana-Márquez Socorro

{"title":"Stress and Cell Death in Testicular Cells","authors":"Juárez-Rojas, Lizbeth, Casillas Fahiel, Retana-Márquez Socorro","doi":"10.4172/2167-0250.1000183","DOIUrl":"https://doi.org/10.4172/2167-0250.1000183","url":null,"abstract":"The success of male reproduction requires the production of a large number of spermatozoa by a unique process known as spermatogenesis. Spermatogenesis is carried out in close association with the Sertoli cells, the only somatic cells of the seminiferous epithelium which are responsible for providing structural, nutritional and endocrine support to the developing germ cells. The seminiferous epithelium of the testes is a rapid proliferation tissue, where the germinal cells, through a large number of mitotic and meiotic divisions prior to their differentiation culminate with the structural and functional formation of spermatozoa. The number of germ cells that Sertoli cells can sustain is maintained by apoptosis, which fulfills the elimination of germ cells with genetic errors, damage to DNA or excess cell production. Apoptosis can also be activated by external factors such as stress, causing alterations in spermatogenesis and testicular involution, which compromises fertility. However, death in testicular cells is not attributed only to apoptosis, as cells use different mechanisms to activate their self-elimination, such as anoikis and autophagy. All of these mechanisms are discussed.","PeriodicalId":15029,"journal":{"name":"Journal of andrology","volume":"20 23","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0250.1000183","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41266661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Centers of Excellence 卓越中心

Journal of andrology Pub Date : 2017-05-29 DOI: 10.4172/2167-0250.1000E114

R. D. Blackledge

引用次数: 0

Extraversion and Neuroticism in Sexually Dysfunctional Men Suffering fromErectile Dysfunction and Premature Ejaculation: A Cross-Sectional Study 性功能障碍男性的外倾性和神经质性患有勃起功能障碍和早泄:一项横断面研究

Journal of andrology Pub Date : 2017-05-06 DOI: 10.4172/2167-0250.1000181

M. Silvaggi, P. Michetti, R. Rossi, A. Fabrizi, C. Leonardo, F. Tripodi, F. Nimbi, C. Simonelli

{"title":"Extraversion and Neuroticism in Sexually Dysfunctional Men Suffering fromErectile Dysfunction and Premature Ejaculation: A Cross-Sectional Study","authors":"M. Silvaggi, P. Michetti, R. Rossi, A. Fabrizi, C. Leonardo, F. Tripodi, F. Nimbi, C. Simonelli","doi":"10.4172/2167-0250.1000181","DOIUrl":"https://doi.org/10.4172/2167-0250.1000181","url":null,"abstract":"The role of personality traits in sexual complaints and dysfunctions is ever more evident. However, the literature is very scarce as to the possible relationships between such personality traits and specific sexual dysfunctions like ED, PE or both, their subtypes as to time of onset and severity levels. The main aim of the present study was to investigate if Neuroticism and Extraversion have different roles and trends in men suffering from PE and/or ED, both lifelong and acquired. Moreover, we verified if, by adopting DSM-IV-TR and DSM-5 criteria for diagnosing PE, some differences emerged in percentages of diagnosed cases. The sample consisted of 222 patients aged 18-70. The International Index of Erectile Function (IIEF-15) was used to assess erectile function, and the Premature Ejaculation Severity Index (PESI) was used to assess the severity of PE dysfunction. Neuroticism and Extraversion were measured with the Eysenck Personality Questionnaire-Revised (EPQ-R). In our results, Neuroticism and Extraversion were dependent on the kind of sexual dysfunction and its severity. These results suggest that type, time of onset and severity of sexual dysfunctions should be considered as related to specific personality characteristics and vice versa.","PeriodicalId":15029,"journal":{"name":"Journal of andrology","volume":"2017 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41621361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2