ISRN Dermatology最新文献_第9页

Biologicals and fetal cell therapy for wound and scar management. 用于伤口和疤痕治疗的生物和胎儿细胞疗法。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-05-18 DOI: 10.5402/2011/549870

Nathalie Hirt-Burri, Albert-Adrien Ramelet, Wassim Raffoul, Anthony de Buys Roessingh, Corinne Scaletta, Dominique Pioletti, Lee Ann Applegate

{"title":"Biologicals and fetal cell therapy for wound and scar management.","authors":"Nathalie Hirt-Burri, Albert-Adrien Ramelet, Wassim Raffoul, Anthony de Buys Roessingh, Corinne Scaletta, Dominique Pioletti, Lee Ann Applegate","doi":"10.5402/2011/549870","DOIUrl":"10.5402/2011/549870","url":null,"abstract":"Few biopharmaceutical preparations developed from biologicals are available for tissue regeneration and scar management. When developing biological treatments with cellular therapy, selection of cell types and establishment of consistent cell banks are crucial steps in whole-cell bioprocessing. Various cell types have been used in treatment of wounds to reduce scar to date including autolog and allogenic skin cells, platelets, placenta, and amniotic extracts. Experience with fetal cells show that they may provide an interesting cell choice due to facility of outscaling and known properties for wound healing without scar. Differential gene profiling has helped to point to potential indicators of repair which include cell adhesion, extracellular matrix, cytokines, growth factors, and development. Safety has been evidenced in Phase I and II clinical fetal cell use for burn and wound treatments with different cell delivery systems. We present herein that fetal cells present technical and therapeutic advantages compared to other cell types for effective cell-based therapy for wound and scar management.","PeriodicalId":14682,"journal":{"name":"ISRN Dermatology","volume":"2011 ","pages":"549870"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30484041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neoadjuvant use of photodynamic therapy in Basal cell and squamous cell carcinomas of the face. 在面部基底细胞癌和鳞状细胞癌的新辅助治疗中使用光动力疗法。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-05-31 DOI: 10.5402/2011/809409

Goran Jeremic, Corey C Moore, Michael G Brandt, Philip C Doyle

引用次数: 0

Nevogenesis: a benign metastatic process? 新生:良性转移过程?

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-04-05 DOI: 10.5402/2011/813513

Andrew L Ross, Margaret I Sanchez, James M Grichnik

引用次数: 13

The pathogenesis of Candida infections in a human skin model: scanning electron microscope observations. 人体皮肤模型中念珠菌感染的发病机制:扫描电镜观察。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-09-05 DOI: 10.5402/2011/150642

A Raz-Pasteur, Y Ullmann, I Berdicevsky

{"title":"The pathogenesis of Candida infections in a human skin model: scanning electron microscope observations.","authors":"A Raz-Pasteur, Y Ullmann, I Berdicevsky","doi":"10.5402/2011/150642","DOIUrl":"https://doi.org/10.5402/2011/150642","url":null,"abstract":"Cutaneous candidiasis is an opportunistic infection that arises, in most cases, from endogenous, saprophytic candidal blastospores that selectively colonize oral, gastrointestinal, vaginal, and cutaneous epithelium. Candida albicans has been regarded as the most common causative agent in human fungal infections. However, other Candida species have become a significant cause of infection. Scanning electron microscope (SEM) observations were used to analyze the capability of C. albicans, C. tropicalis, and C. parapsilosis to adhere to human skin model, used in this study, which was found to mimic the human skin in vivo. The skin sections were inoculated with low and high concentration of the yeasts and followed for 1 and 5 days; then they were viewed by SEM. The electron microscopy observations revealed that all three yeasts tested adhered to the skin but C. albicans covered the entire skin model to a higher extent than C. tropicalis or C. parapsilosis. Mucin-like material coated the blastoconidia mainly in C. albicans. All Candida species have shown characteristics resembling biofilm formation. The use of human skin sections for ex vivo evaluation of adherence of various yeasts may partially explain the predominance of C. albicans in cutaneous pathogenicity.","PeriodicalId":14682,"journal":{"name":"ISRN Dermatology","volume":"2011 ","pages":"150642"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30485156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27

Xanthoma disseminatum in a pair of blind, deaf male twins. 一对失明、失聪的男性双胞胎患有广泛性黄瘤。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-03-15 DOI: 10.5402/2011/342909

Naveed Natanzi, David Peng, Eli Ahdoot, Sandra Ghatan, Amy Reinstandler, Ramin Ram

引用次数: 3

Nevus senescence. 痣衰老。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-06-22 DOI: 10.5402/2011/642157

Andrew L Ross, Margaret I Sanchez, James M Grichnik

引用次数: 0

Unusual presentation of a rare tumor of the dorsal surface of the foot. 脚背表面罕见肿瘤的罕见表现。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-03-31 DOI: 10.5402/2011/704549

O Hocar, H Yacoubi, N Akhdari, S Amal, F Ait Essi, M Latifi, H Rais, B Belaabidia

引用次数: 4

Immunohistochemical Reactivity of the 14F7 Monoclonal Antibody Raised against N-Glycolyl GM3 Ganglioside in Some Benign and Malignant Skin Neoplasms. 抗n -糖基GM3神经节苷脂14F7单克隆抗体在一些良恶性皮肤肿瘤中的免疫组织化学反应性

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-04-10 DOI: 10.5402/2011/848909

Rancés Blanco, Enrique Rengifo, Charles E Rengifo, Mercedes Cedeño, Milagros Frómeta, Adriana Carr

引用次数: 35

Severe Hair Loss of the Scalp due to a Hair Dye Containing Para phenylenediamine. 由于染发剂含有对苯二胺导致严重的头皮脱发。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-06-07 DOI: 10.5402/2011/947284

Waka Ishida, Teruhiko Makino, Tadamichi Shimizu

引用次数: 24

Pilot Study of 15 Patients Receiving a New Treatment Regimen for Androgenic Alopecia: The Effects of Atopy on AGA. 接受雄激素性脱发新治疗方案的15例患者的初步研究:特应性对AGA的影响。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-04-11 DOI: 10.5402/2011/241953

A W Rafi, R M Katz

{"title":"Pilot Study of 15 Patients Receiving a New Treatment Regimen for Androgenic Alopecia: The Effects of Atopy on AGA.","authors":"A W Rafi, R M Katz","doi":"10.5402/2011/241953","DOIUrl":"https://doi.org/10.5402/2011/241953","url":null,"abstract":"Background. We examined the efficacy of a new regimen to treat AGA, with attention to male patients who are atopic. Objective. To assess the efficacy of a four-part regimen for the treatment of AGA in atopic and nonatopic patients. NuH Hair is a novel topical combination of finasteride, dutasteride, and minoxidil, which is blended in a hypoallergenic lotion. The other three components included Rogaine foam, Propecia, and ketoconazole shampoo. Methods. A prospective pilot study was conducted in 15 patients. All patients were assessed for the presence of atopy. Each patient served as their own control. All patients were treated specifically with NuH Hair and were given the option to add any of the other components of the protocol to their regimen. Photographs were taken of each patient's scalp at months 0, 1, 3, 6, and 9. Results. All 15 patients demonstrated significant growth of hair. In those patients who utilized all 4 components, significant growth was achieved in as little as 30 days. In those patients who choose only to utilize NuH Hair, significant growth was demonstrated after 3 months. Conclusion. Aggressively treating AGA achieves significant and rapid growth of new hair. This is effective in atopic and nonatopic male patients.","PeriodicalId":14682,"journal":{"name":"ISRN Dermatology","volume":"2011 ","pages":"241953"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2011/241953","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30485158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14