JACC: Cardiovascular Interventions最新文献

{"title":"Recommended Steps for UNICORN With Balloon-Expandable Valves","authors":"Kwong-Yue Eric Chan MBBS, Chun-Ka Wong MBBS, Tai-Leung Chan MBBS, Gilbert H.L. Tang MD MSc MBA, Simon Cheung-Chi Lam MBBS","doi":"10.1016/j.jcin.2025.05.034","DOIUrl":"https://doi.org/10.1016/j.jcin.2025.05.034","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Outcomes of Real-World Transcatheter Tricuspid Valve Replacement.","authors":"Domenico Angellotti,Isabel Mattig,Daryoush Samim,Björn Goebel,Charlotte Jantsch,Barbara Rubinic,Tobias Ruf,Tobias Geisler,Mirjam Kessler,Matti Adam,Lukas Stolz,Varius Dannenberg,Mohammad Kassar,Konstantinos Stathogiannis,Vincenzo Cesario,Nicolas Dumonteil,Michael Chrissoheris,Konstantinos Spargias,Stephan Baldus,Wolfgang Rottbauer,Muhammed Gerçek,Philippe M Bartko,Harald Lapp,Henryk Dreger,Jörg Hausleiter,Philipp Lurz,Stephan Windecker,Volker Rudolph,Fabien Praz","doi":"10.1016/j.jcin.2025.06.002","DOIUrl":"https://doi.org/10.1016/j.jcin.2025.06.002","url":null,"abstract":"BACKGROUNDTranscatheter tricuspid valve replacement (TTVR) has been recently approved for the treatment of patients with severe tricuspid regurgitation (TR). Real-world evidence regarding the commercial use of TTVR is lacking.OBJECTIVESThe aim of this study was to investigate the real-world safety and efficacy of the EVOQUE TTVR system in patients with severe TR treated at 12 experienced heart valve centers in 5 European countries.METHODSConsecutive patients treated with the EVOQUE system since approval in Europe (October 2023 to February 2025) were included in this retrospective analysis. Clinical outcomes were assessed at 30-day follow-up.RESULTSThe study included 176 patients (mean age 77.8 years, 72.0% women, median TRI-SCORE 5 points [IQR: 2 points]). At a median follow-up time of 30 days (IQR: 2 days), severe or greater TR was reduced to mild or none in 126 of 128 patients (98.4%; P < 0.001). NYHA functional class improved from 20.2% (28 of 138) class I or II at baseline to 79.7% (110 of 138; P) at 1 month (P < 0.001), with signs of improved hepatorenal function (estimated glomerular filtration rate 47.0 ± 19.9 mL/min/1.73 m2 vs 53.7 ± 23.3 mL/min/1.73 m2 [P < 0.001]; bilirubin 14.2 ± 8.8 μmol/L vs 11.0 ± 9.8 μmol/L [P < 0.001]). Massive or torrential TR at baseline was more common among patients who improved compared with those with stable or worsening NYHA functional class (75 of 98 [76.5%] vs 20 of 40 [50.0%]; P = 0.004). Permanent pacemaker implantation was required in 21 of 111 pacemaker-naive patients (18.9%), in particular those with conduction disturbances at baseline (OR: 4.53; 95% CI: 1.73-11.82; P = 0.002). Moderate or severe right ventricular dysfunction was an independent predictor of clinical failure at 1-month follow-up (OR: 3.60; 95% CI: 1.39-9.32, P = 0.008).CONCLUSIONSTR elimination following TTVR in a real-world setting was associated with significant symptom and end-organ functional improvement. Patients with massive or torrential TR were more likely to experience functional improvement. Pre-existing conduction disturbances are associated with increased risk for pacemaker implantation, while baseline right ventricular dysfunction is a strong predictor of adverse clinical outcomes.","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Edge-to-Edge Repair for Atrial and Ventricular Secondary Mitral Regurgitation: Insights From the REPAIR Study.","authors":"Philipp von Stein,Lukas Stolz,Jean Marc Haurand,Matthias Gröger,Felix Rudolph,Donika Mustafa,Jannik Jobst,Christoph Alexander Mues,Amir Abbas Mahabadi,Isabel A Hoerbrand,Carl Schulz,Atsushi Sugiura,Jennifer von Stein,Christos Iliadis,Philipp Lurz,Muhammed Gerçek,Patrick Horn,Mirjam Kessler,Guido Ascione,Tienush Rassaf,Marcel Weber,Niklas Schofer,Mathias Konstandin,Florian Schindhelm,Helge Möllmann,Bernhard Unsöld,Henning Guthoff,Stephan Baldus,Wolfgang Rottbauer,Volker Rudolph,Juan F Granada,Jörg Hausleiter,Roman Pfister,Victor Mauri,","doi":"10.1016/j.jcin.2025.05.031","DOIUrl":"https://doi.org/10.1016/j.jcin.2025.05.031","url":null,"abstract":"BACKGROUNDSecondary mitral regurgitation (SMR) has 2 phenotypes: atrial (aSMR) and ventricular (vSMR). The role of mitral valve transcatheter edge-to-edge repair (M-TEER) in aSMR remains less defined, with limited evidence on the PASCAL implant (Edwards Lifesciences).OBJECTIVESThe authors sought to evaluate and compare outcomes of SMR phenotypes undergoing M-TEER.METHODSREPAIR (REgistry of PAscal for mItral Regurgitation) is an investigator-initiated, multicenter registry of patients undergoing M-TEER. aSMR was defined by left atrial dilation with preserved left ventricular size and ejection fraction. Outcomes included MR ≤1+ at discharge, technical success, NYHA functional class improvement, and 1-year survival.RESULTSAmong 915 patients (166 [18%] aSMR, 749 [82%] vSMR), the median follow-up was 491 days (Q1-Q3: 360-833 days). MR ≤1+ was achieved in 77.2% vs 71.4% (P = 0.162), with technical success in 97.0% vs 98.3% (P = 0.446). NYHA functional class improved in both phenotypes (P < 0.001), with 61.2% vs 61.3% in functional class ≤II at follow-up (P > 0.999). One-year survival was 88.4% (95% CI: 82.8%-94.4%) vs 86.0% (95% CI: 83.1%-89.0%; P = 0.346). In aSMR patients, 1-year survival was significantly lower in patients with baseline tricuspid regurgitation (TR) grade ≥moderate compared with those with <moderate TR (84.3% [95% CI: 77.0%-92.3%] vs 100.0% [95% CI: 100.0%-100.0%]; P = 0.041). In vSMR patients, survival was similar between ≥moderate and <moderate baseline TR (83.9% [95% CI: 79.8%-88.2%] vs 89.3% [95% CI: 85.0%-93.8%]; P = 0.051).CONCLUSIONSM-TEER effectively reduces MR to ≤1+ and improves symptoms in both aSMR and vSMR. Particularly in aSMR, ≥moderate baseline TR is linked to worse outcomes, warranting consideration as an additional treatment target.","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simplified and Improved Commissural Alignment Technique With the Supra-Annular, Self-Expanding Evolut FX System.","authors":"Chieh Yang Christopher Koo,George Petrossian,Newell Robinson,William Chung,Matthew Henry,Andrew Berke,Kristin Pasquarello,Ziad Ali,Omar Khalique,Jaffar M Khan","doi":"10.1016/j.jcin.2025.06.003","DOIUrl":"https://doi.org/10.1016/j.jcin.2025.06.003","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"102 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From TAVR to TTVR: Echoes of Progress and Caution.","authors":"Mohamad Alkhouli,Kuan-Chih Huang","doi":"10.1016/j.jcin.2025.06.001","DOIUrl":"https://doi.org/10.1016/j.jcin.2025.06.001","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"639 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"800.21 Aortic Valve Replacement: Do Hospital Location and Size Matter?","authors":"C. Umeh, R. Gupta, G. Kaur, R. Dhawan, B. Eghreriniovo, J. Obi, S. Maguwudze, P. Mahdavian, S. Kumar, M. Zainea, J. Mohan","doi":"10.1016/j.jcin.2024.01.246","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.01.246","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"141 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140464230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"400.25 Comparing the Clinical Outcomes of Fractional Flow Reserve and Intravascular Ultrasonography in Guiding Percutaneous Coronary Intervention","authors":"A. M. Balakrishna, A. Aboeata, A. Jhand","doi":"10.1016/j.jcin.2024.01.192","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.01.192","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"308 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140466417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"800.6 Impact of Hospital Procedural Volume on the Outcomes of Transcatheter End-to-End Mitral Valve Repair in Clinical Trials Non-Eligible Patients","authors":"A. Maraey, H. Elsharnoby, N. Bardia, M. Mahmoud, N. Chaaban, A. Elzanaty, M. Patel, A. Fares, O. Sajdeya, M. Khalil","doi":"10.1016/j.jcin.2024.01.266","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.01.266","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"54 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140464368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"700.06 Comprehensive Radiation Shield Minimizes Operator Radiation Exposure and Obviates Need for Lead Aprons in Coronary and Structural Intervention","authors":"D. Rizik","doi":"10.1016/j.jcin.2024.01.224","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.01.224","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"39 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140464899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"800.45 Single-Center Comparison of Watchman vs Amulet Left Atrial Appendage Closure Device to Treat Patients with Non-Valvular Atrial Fibrillation","authors":"A.S. Bahga, J. Smazil, L. Roark, J. Friant, B. Conway, A. Karim, S. Nathan, J. Paul, P. Sharma, J. Blair, A. Shah","doi":"10.1016/j.jcin.2024.01.254","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.01.254","url":null,"abstract":"","PeriodicalId":14666,"journal":{"name":"JACC: Cardiovascular Interventions","volume":"70 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140463112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}