Irish Journal of Medical Science (1971 -)最新文献

{"title":"Book Review of \"Safety as we watch: anaesthesia in Ireland 1847–1998, by Declan Warde, Joseph Tracey, John Cahill\"","authors":"J. Loughrey","doi":"10.1007/s11845-022-03188-3","DOIUrl":"https://doi.org/10.1007/s11845-022-03188-3","url":null,"abstract":"","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"54 1","pages":"2029"},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77958694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trace elements released from dental implants with periimplantitis: a cohort study.","authors":"Gelengül Gürbüz-Urvasızoğlu, Mert Ataol, Fatma Betül Özgeriş","doi":"10.1007/s11845-022-03020-y","DOIUrl":"10.1007/s11845-022-03020-y","url":null,"abstract":"<p><strong>Background: </strong>Pure titanium and Ti6Al4V alloy have been in use as dental implant contemporarily. Trace element release from implant bodies is a possible health problem. Well-healed and osseointegrated intrabony implants are only in contact with bone and blood, but in the case of periimplantitis, the possibility of corrosion and the release of trace elements from dental implant surfaces increases due to contact with external factors.</p><p><strong>Aims: </strong>The aim of this study is to evaluate the trace element levels in the blood serum and saliva of patients who have dental implants with periimplantitis compared with the control group.</p><p><strong>Methods: </strong>This study included 25 patients diagnosed with periimplantitis and 25 participants with healthy osseointegrated implants as the control group. The trace element levels in blood serum and saliva were measured by inductively coupled plasma-mass spectrometry (ICP-MS) and results were analyzed statistically.</p><p><strong>Results: </strong>There is no statistically significant difference between groups for saliva samples except the aluminum (Al) levels of the study group are significantly lower than the control group (p < 0.05) and the mercury (Hg) levels of the study group are significantly higher than the control group (p < 0.05). On the other hand, there is a significant decrease in titanium (Ti), chromium (Cr), and iodine (I) in the blood serum samples of the study group (p < 0.05). There is no significant difference between the groups for other measured trace elements in the blood serum (p > 0.05).</p><p><strong>Conclusion: </strong>There is no statistically significant increase in titanium or aluminum levels in the study group compared with the control group.</p>","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"111 1","pages":"2305-2310"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76218733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of MINOCA syndrome and HEART score in patients presenting to the emergency department with panic attack and chest pain complaints.","authors":"Bahadır Taslidere, Ahmet Atsiz","doi":"10.1007/s11845-022-03018-6","DOIUrl":"10.1007/s11845-022-03018-6","url":null,"abstract":"<p><strong>Background: </strong>Patients presenting with chest pain may or may not be experiencing a panic attack. Is chest pain caused by a panic attack or myocardial infarction with non-obstructive coronary arteries (MINOCA) syndrome?</p><p><strong>Aim: </strong>In this study, we evaluated both MINOCA syndrome and HEART score in patients who presented to the emergency department with panic attacks and chest pain.</p><p><strong>Method: </strong>Patients who applied to the emergency department with panic disorder and chest pain complaints were included. Patients who met the MINOCA diagnostic criteria were identified. The study was completed with 143 eligible patients out of a total of 217 patients evaluated. The patients were divided into two groups. The first group was those whose symptoms and test results were consistent with MINOCA. The second group was composed of those whose chest pain was considered non-specific. The HEART score of all patients was calculated. The demographic characteristics, symptoms, and HEART scores were compared between the groups.</p><p><strong>Results: </strong>Of the 143 patients evaluated in the study, 62 (43.3%) were male and 81 (56.7%) were female. While the mean HEART score was 4.7 ± 1.5 in the MINOCA group, it was 2.0 ± 1.0 in the non-cardiac group, a statistically significant difference.</p><p><strong>Conclusion: </strong>Clinicians should pay attention to the patient's age, gender, number of attacks per week, HEART score, and which symptoms (palpitations, shortness of breath, and fear of death) are present in patients who meet the panic attack diagnostic criteria. Clinicians should be alert to the MINOCA syndrome in panic attack patients.</p>","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"293 2 1","pages":"2351-2356"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72920583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shaun R McCann: Medicine Matters. 40 years working within the Irish healthcare system","authors":"W. Tormey","doi":"10.1007/s11845-022-03140-5","DOIUrl":"https://doi.org/10.1007/s11845-022-03140-5","url":null,"abstract":"","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"66 1","pages":"1537-1538"},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73883668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: The use of glycosylated hemoglobin (HbA1c) as a predictor of the severity of acute coronary syndrome among diabetic patients","authors":"A. Albashir, O. Elawad, H. Mohamed","doi":"10.1007/s11845-022-02968-1","DOIUrl":"https://doi.org/10.1007/s11845-022-02968-1","url":null,"abstract":"","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"31 1","pages":"1471"},"PeriodicalIF":0.0,"publicationDate":"2022-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84515808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decision-making in awake fibre optic intubation for patients with severe dentofacial infection: which patients will require fibre optic intubation?","authors":"Conor M Bowe, Jessie A Elliott, Tom Schnittger, Gerard J Kearns","doi":"10.1007/s11845-019-02145-x","DOIUrl":"10.1007/s11845-019-02145-x","url":null,"abstract":"<p><strong>Background: </strong>Risk factors for advanced airway intervention among patients with dentofacial infection (DFI) are poorly understood. The appropriate delivery of clinical care to this patient group raises challenging anaesthetic service provision issues. The purpose of this study was to identify factors which may predict a requirement for an awake fibre optic intubation (AFOI) technique for airway management in this patient population.</p><p><strong>Methods: </strong>A retrospective analysis of data for consecutive patients admitted with DFI were analysed at the Oral & Maxillofacial department at St James's Hospital, Dublin from July 2014-July 2015 was carried out. Receiver operating characteristic analysis determined optimal cut-off values predictive of AFOI, and multivariate logistic regression determined independent risk factors for AFOI.</p><p><strong>Results: </strong>One hundred and twenty-five patients (64 male, 61 female) were admitted with DFI. The mean age was 35.9 years (range 16-91). AFOI was carried out in 58 (67.4%) patients who required GA. Increasing age was associated with an increase likelihood of AFOI (P = 0.047 95% CI 1.07(1.00-1.14). Reduced mouth opening was significantly associated with requirement for AFOI (28.8 ± 8.6 vs. 14.8 ± 8.6 mm, P < 0.0001). On receiver operating characteristic (ROC) analysis, mouth opening predicted requirement for AFOI with 87% accuracy (AUC 0.87 [95% CI 0.80-0.95], P < 0.0001). Using a cut-off value of 16.5 mm predicted subsequent AFOI with 96.7% (95% CI 78.1-100.0%) specificity and 65.6% (95% CI 51.4-77.8%) sensitivity. Initial C-reactive protein (CRP) was significantly associated with requirement for AFOI (60.1 ± 40.0 vs. 121.3 ± 89.8, P = 0.002). A CRP value of over 110 mg/L predicted subsequent AFOI with 95.8% (95% CI 78.9-100.0%) specificity.</p><p><strong>Conclusion: </strong>Increasing age, reduced mouth opening < 16.5 mm, and an increased serum admission CRP > 100 mg/L on admission significantly increase the requirement for AFOI on multivariate and univariate regression analysis. The availability of anaesthetists experienced in AFOI is essential for safe management of these patients.</p>","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"95 1","pages":"1039-1045"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76734395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sponsorship, advertising and alcohol control in Ireland: the importance of both premises and products in regulating intoxigenic environments.","authors":"Frank Houghton, Derek McInerney","doi":"10.1007/s11845-019-02154-w","DOIUrl":"10.1007/s11845-019-02154-w","url":null,"abstract":"","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"17 1","pages":"1035-1037"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84702417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Participatory development of a patient-clinician communication tool to enhance healthcare transitions for young people with 22q11.2.","authors":"Lorna Kerin, Diarmuid Lynch, Fiona McNicholas","doi":"10.1007/s11845-019-02104-6","DOIUrl":"10.1007/s11845-019-02104-6","url":null,"abstract":"<p><strong>Background: </strong>Individuals with the rare genetic disorder, 22q11.2 deletion syndrome (22q11.2ds), face particular challenges with transition from paediatric to adult health services due to complex physical and mental health care needs, often further complicated by intellectual disability (ID). To date, the lived experience of these young people navigating this complex journey has not been well researched.</p><p><strong>Aim: </strong>The project sought to understand the lived experiences of young women with 22q11.2ds transitioning from child to adult health services and to elicit recommendations for improvement.</p><p><strong>Methods: </strong>Following ethical approval, six female participants, aged 19-35 years, were recruited through the family support organisation 22q11 Ireland. Adhering to participatory action research (PAR) principles, four full day sessions using creative research methodologies were conducted over a 4-month period.</p><p><strong>Results: </strong>Participants reported significant difficulties navigating transition between and within clinical services, and reported a lack of information transfer between healthcare services which required multiple retelling of their story. They expressed a low sense of confidence in new healthcare providers and reported ambivalence regarding their own agency and ability to manage clinical appointments without family or 'keyworker' support. Participants co-designed a patient-clinician communication tool to assist in information transfer and to capture salient features of any healthcare consultation.</p><p><strong>Conclusions: </strong>There is a recognised need to strengthen transition pathways. This is especially true in this at risk group, given the poorer outcomes associated with transitions in youth with ID along with the additive effect of medical and mental health and learning difficulties that often co-occur in 22q11.2ds. A patient-clinician communication tool, designed by participants, offers a pragmatic approach to optimise healthcare transitions, support continuity of healthcare and personal autonomy.</p>","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"40 1","pages":"761-769"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75426763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of drug interactions and prescription appropriateness in elderly patients.","authors":"Elisa Petrini, Gian Paolo Caviglia, Rinaldo Pellicano, Giorgio Maria Saracco, Mario Morino, Davide Giuseppe Ribaldone","doi":"10.1007/s11845-019-02148-8","DOIUrl":"10.1007/s11845-019-02148-8","url":null,"abstract":"<p><strong>Background: </strong>In Europe, adverse drug reactions and drug interactions are the cause of considerable morbidity and mortality. In over 75s, hospital access due to adverse drug reactions can be as high as 1 in every 3.</p><p><strong>Aims: </strong>To assess the quality of the prescribed polytherapies in the territory, in terms of the risk of drug interactions and of prescription appropriateness, in over 75s.</p><p><strong>Methods: </strong>Randomly selected patients, over 75s, were analysed among the patients of 3 general practitioners. Their data were analysed with the INTERCheck® software. This software provided the list of drug interactions deriving from the chronic therapies. The program also provided the Beers criteria and the STOPP criteria related to the drugs, highlighting potentially inappropriate drugs.</p><p><strong>Results: </strong>A total of 188 patients were included in the study. A total of 216 serious or very serious drug interactions have been identified. A total of 92 patients (48.9%) were at risk of at least one serious or very serious interaction. The cut-off of the correlation between the number of drugs taken and the risk of incurring a serious or very serious interaction was found to be 5 (AUC = 0.833, sensitivity = 87%, p < 0.001). Patients on ≥ 4 drugs were at risk of prescriptive inappropriateness with a sensitivity of 84% (AUC = 0.781, p < 0.0001).</p><p><strong>Conclusions: </strong>Focusing on patients with at least 4 drugs in therapy is the right strategy to reduce the risks associated with polypharmacy.</p>","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"29 10 1","pages":"953-959"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82729304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the 2016 World Health Organization Classification of Tumours of the Central Nervous System: an Irish experience.","authors":"Conor Fearon, Teresa Loftus, Amber Lynn Byrne, Josephine Heffernan, Maeve Cooney, Ciara Heeney, Andrea Walsh, Jennifer Lorigan, Alan Beausang, Jane Cryan, Michael Farrell, Francesca Brett","doi":"10.1007/s11845-019-02144-y","DOIUrl":"10.1007/s11845-019-02144-y","url":null,"abstract":"<p><p>The 2016 World Health Organization Classification of Tumours of the Central Nervous System Tumours represents the most significant update to neuro-oncological tumour classification to date, compared with previous updates. This update reflects the substantial advances in molecular and genetic understanding of both adult and childhood brain tumours which have occurred in recent years. These advances have meant that an increasing array of molecular tests are required to definitively classify a tumour, allowing for a more precise integrated pathological diagnosis, but at the expense of a more challenging pathology workup. We review the changes incorporated into the 2016 classification and describe the impact of these changes in an Irish neuropathology laboratory.</p>","PeriodicalId":14616,"journal":{"name":"Irish Journal of Medical Science (1971 -)","volume":"36 1","pages":"799-803"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76166507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}