Japanese journal of microbiology最新文献_第9页

Mode of Synergism between Colistin and Sulfisomezole in Inhibiting the Growth of Proteus Organism 粘菌素与磺胺硫唑抑制变形杆菌生长的协同作用模式

Japanese journal of microbiology Pub Date : 1967-03-01 DOI: 10.1111/J.1348-0421.1967.TB00339.X

Y. Onozawa, K. Kumagai, N. Ishida

{"title":"Mode of Synergism between Colistin and Sulfisomezole in Inhibiting the Growth of Proteus Organism","authors":"Y. Onozawa, K. Kumagai, N. Ishida","doi":"10.1111/J.1348-0421.1967.TB00339.X","DOIUrl":"https://doi.org/10.1111/J.1348-0421.1967.TB00339.X","url":null,"abstract":"When either colistin at 1,000 μg/ml or sulfisomezole at 125 μg/ml was used separately, growth of a strain of Proteus mirabilis was not inhibited. However, when 1 μg/ml of colistin and 25 μg/ml of sulfisomezole were used together in agar media, growth was inhibited. The synergistic action of colistin and sulfisomezole was also demonstrated in broth culture, when a smaller inoculum such as 106 cells/ml was used. The lethal and lytic effect of this synergism parallels the characteristic effect of colistin towards colistin-sensitive gram-negative organisms. When the mode of this synergistic action was analyzed by adding each compound in sequence to a growing culture of Proteus, it was found that growth of organism for about 4 generations in the presence of sulfisomezole was a prerequisite for revealing the lethal and lytic effects of colistin. In cultures where these two compounds were present at the beginning of incubation, the synergistic effect was abolished by the addition of p-aminobenzoic acid (PABA) at an early stage of incubation, but not at a late stage. Methionine, serine, and betaine, when used together, had the same effect as PABA. An insufficiency of the three compounds induced by sulfisomezole, was considered to afford the receptor site of colistin to Proteus.","PeriodicalId":14559,"journal":{"name":"Japanese journal of microbiology","volume":"86 1","pages":"221-227"},"PeriodicalIF":0.0,"publicationDate":"1967-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74611490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Grouping of RNA Phages by a Millipore Filtration Method 用微孔过滤法对RNA噬菌体进行分组

Japanese journal of microbiology Pub Date : 1967-03-01 DOI: 10.1111/J.1348-0421.1967.TB00337.X

T. Miyake, T. Shiba, I. Watanabe

引用次数: 17

Two types of slowly growing, nonphotochromogenic mycobacteria obtained from soil by the mouse passage method: Mycobacterium terrae and Mycobacterium novum. 用小鼠传代法从土壤中获得两种生长缓慢、不显光的分枝杆菌:地分枝杆菌和新分枝杆菌。

Japanese journal of microbiology Pub Date : 1967-03-01 DOI: 10.1111/J.1348-0421.1967.TB00333.X

M. Tsukamura

{"title":"Two types of slowly growing, nonphotochromogenic mycobacteria obtained from soil by the mouse passage method: Mycobacterium terrae and Mycobacterium novum.","authors":"M. Tsukamura","doi":"10.1111/J.1348-0421.1967.TB00333.X","DOIUrl":"https://doi.org/10.1111/J.1348-0421.1967.TB00333.X","url":null,"abstract":"Two types of slowly growing, nonphotochromogenic mycobacteria, Mycobacterium terrae and Mycobacterium novum, were isolated from soil by mouse body passage method. The former was presented previously by the present author as a new species. Its characteristics are better clarified in this paper based on the data of 93 strains. Mycobacterium novum is a slowly growing nonphotochromogen. It grows at 10 to 14 days on egg media and does not grow on Sauton agar. It grows on Ogawa egg medium containing either 0.2% (w/v) sodium p-aminosalicylate, 0.1% (w/v) sodium salicylate or 0.25 mg/ml NH2OH·HCl. It is differentiated from M. tuberculosis, M. bovis and M. microti by these characters. It grows at 28 C and 37 C, but does not grow at 45 C. Other characteristics are: nitrate not reduced; negative two week arylsulphatase; negative niacin test; and no amidase clemonstrated. None of the carbohydrates and nitrogen compounds tested could be utilized as the sole source of carbon or of nitrogen in synthetic agar medium. It survived in mouse organs for three to four weeks. It was noticed that these mycobacteria occur very commonly in soil.","PeriodicalId":14559,"journal":{"name":"Japanese journal of microbiology","volume":"87 1","pages":"163-172"},"PeriodicalIF":0.0,"publicationDate":"1967-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81288860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Drug Resistance of Enteric Bacteria:XII. Unique Substrate Specificity of Penicillinase Produced by R Factor 肠道细菌的耐药性:12。R因子产生青霉素酶的独特底物特异性

Japanese journal of microbiology Pub Date : 1967-03-01 DOI: 10.1111/J.1348-0421.1967.TB00334.X

R. Egawa, T. Sawai, S. Mitsuhashi

引用次数: 76

Some Ionic Factors Affecting Efficiency of Infection of African Green Monkey Kidney Cultures with SV40 DNA in Isotonic Saline Media 等渗盐水培养基中影响非洲绿猴肾SV40 DNA感染效率的若干离子因素

Japanese journal of microbiology Pub Date : 1967-03-01 DOI: 10.1111/J.1348-0421.1967.TB00340.X

A. Ishikawa, A. Furuno

引用次数: 4

Drug Resistance of Enteric Bacteria:XI. Isolation of Shigella Strains in Hetero-R State 肠道细菌的耐药性:11。异r态志贺氏菌的分离

Japanese journal of microbiology Pub Date : 1967-03-01 DOI: 10.1111/J.1348-0421.1967.TB00332.X

Tokumitsu Tanaka, H. Hashimoto, Y. Nagai, S. Mitsuhashi

引用次数: 17

Drug Resistance of Enteric Bacteria:X. Recombination of Defective R (TC) Factor with Other Episomes 肠道细菌的耐药性:X。缺陷R (TC)因子与其他发作的重组

Japanese journal of microbiology Pub Date : 1967-02-01 DOI: 10.1111/J.1348-0421.1967.TB00330.X

K. Harada, M. Kameda, Mitsue Suzuki, S. Mitsuhashi

引用次数: 18

Prevalence of Transferable Drug Resistance in Drug‐Resistant Bacteria Isolated from Urinary Tract Infections in Japan 日本尿路感染中分离的耐药细菌可转移耐药性的流行情况

Japanese journal of microbiology Pub Date : 1967-02-01 DOI: 10.1111/J.1348-0421.1967.TB00324.X

Y. Naide, T. Kawamura, K. Makino, H. Tamura, Tsutomu Watanabe

引用次数: 7

Some Physical Properties of Phage F of Bacillus subtilis 枯草芽孢杆菌噬菌体F的一些物理性质

Japanese journal of microbiology Pub Date : 1967-02-01 DOI: 10.1111/J.1348-0421.1967.TB00331.X

Kenji Watanabe, W. Szybalski

引用次数: 1

Changes in the Phage‐Typing Patterns of Staphylococci Following Lysogenization 葡萄球菌溶原后噬菌体分型模式的变化

Japanese journal of microbiology Pub Date : 1967-02-01 DOI: 10.1111/J.1348-0421.1967.TB00328.X

H. Oshima, U. Kawaharada, T. Kasuga, S. Mitsuhashi

引用次数: 3