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MOJ Bioequivalence & Bioavailability最新文献

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Assessment of effect of treatments on WBCS count variations in diabetic-HCV patients treated with three different regimens of hepatitis 评估三种不同肝炎治疗方案对糖尿病-丙型肝炎患者白细胞计数变化的影响
MOJ Bioequivalence & Bioavailability Pub Date : 2018-08-21 DOI: 10.15406/MOJBB.2018.05.00106
A. Mangi, Muhammad Khalid Khan, H. Khan, F. Rehman, Barkat Ali Khan, Awais Ahmed Juno, N. Lund, W. Malhani
{"title":"Assessment of effect of treatments on WBCS count variations in diabetic-HCV patients treated with three different regimens of hepatitis","authors":"A. Mangi, Muhammad Khalid Khan, H. Khan, F. Rehman, Barkat Ali Khan, Awais Ahmed Juno, N. Lund, W. Malhani","doi":"10.15406/MOJBB.2018.05.00106","DOIUrl":"https://doi.org/10.15406/MOJBB.2018.05.00106","url":null,"abstract":"Purpose The objective of the study was to assess the effect of different three HCV regmin therapies Methodology The reterospective cross sectional study was carried out in KPK Pakistan the total sample size was taken and data was collected with the help of questionnaire Results The mean WBCs count and variations in and diabetic HCV patients respectively The WBCs WBCs WBCs represent the white blood cells counts which were noted periodically before initiation the therapy months after the therapy and months after the therapy The mean WBCs count of patients who consumed IFN RBV is which dropped to and then elevated to Similarly the WBCs count dropped from to in first three months and then increased to at the th months in patients who consumed Peg ifn RBV Conclusion Infected population received anti HCV therapies INF RIB and PEG INF RIB during hepatitis C treatment showed a uniform reduction in mean white blood cells count SOF RBV showed a lower reduction in WBCs count nbsp","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"304 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115908775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Nigella sativa seeds extracts on clinically important bacterial and fungal species 黑草种子提取物对临床重要细菌和真菌种类的影响
MOJ Bioequivalence & Bioavailability Pub Date : 2018-08-16 DOI: 10.15406/mojbb.2018.05.00105
S. B. Shah, Syed Sadaqat Shah, L. Sartaj, S. Zaman, M. Bilal, Muhammad Salman
{"title":"Effect of Nigella sativa seeds extracts on clinically important bacterial and fungal species","authors":"S. B. Shah, Syed Sadaqat Shah, L. Sartaj, S. Zaman, M. Bilal, Muhammad Salman","doi":"10.15406/mojbb.2018.05.00105","DOIUrl":"https://doi.org/10.15406/mojbb.2018.05.00105","url":null,"abstract":"Salmonella typhi and Salmonella paratyphi A are the main causative agents of enteric fever.1,2 The infection is common in those areas where unhygienic conditions prevailed. According to estimation round about 27 million people become victim of typhoid annually, of this 27 million 200000 people die.3 More than 95% of patients can be recovering by providing appropriate therapy. But study suggests that 2-5% of typhoid patients got chronic gallbladder infection. Gallbladder infection may be due to bile or directly from blood. Salmonella specie is acquiring resistance to antibiotics such as ciprofloxacin, ampicillin, cotrimoxazole, chloramphenicol and ceftriaxone, which has made difficult the management and treatment of enteric fever.1","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126667804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Comparative study between the effect of Parkia Biglobosa (JACQ) benth and conventional antibiotics against multiple antibiotic resistant uropathogenic bacteria (MARUB) 大叶Parkia bilobosa (JACQ)底液与常规抗生素对多重耐药尿路病原菌(MARUB)的疗效比较研究
MOJ Bioequivalence & Bioavailability Pub Date : 2018-08-08 DOI: 10.15406/mojbb.2018.05.00103
Dr Oludare temitope Osuntokun, Taiye Anangwureyi Jemilaiye, Akinrodoye Ar
{"title":"Comparative study between the effect of Parkia Biglobosa (JACQ) benth and conventional antibiotics against multiple antibiotic resistant uropathogenic bacteria (MARUB)","authors":"Dr Oludare temitope Osuntokun, Taiye Anangwureyi Jemilaiye, Akinrodoye Ar","doi":"10.15406/mojbb.2018.05.00103","DOIUrl":"https://doi.org/10.15406/mojbb.2018.05.00103","url":null,"abstract":"Urinary tract infections (UTI) are common infections. It is estimated that 150 million urinary tract infections occur yearly worldwide, resulting in more than six billion dollar in direct healthcare cost.1 Complicated UTIs include those in patients with stones or obstructive Uropathies and in patients with catheter-related infections. Urinary tract infections often contribute to a frequent cause of morbidity in out-patients as well as hospitalized patients.2 These infections are often associated with nosocomial, antibiotic-resistant3 Gram negative and Gram positive bacteria.4 The etiological agents of UTIs are predictable, with Escherichia coli being the commonest pathogen.5 Clinical experience has indicated the presence of numerous cases of antibiotic resistance to common antibiotics by Uropathogens in both developed and developing countries.6 Resistant to newer and more potent antimicrobials are no exceptions but this has decreased the effectiveness of some standard regimes, and thus, the management of urinary tract infections becoming complicated with limited therapeutic options. The emergence of multidrug resistance (MDR) in Uropathogens has further narrowed down the therapeutic options and the need for alternative treatment option. Multidrug resistance (MDR) can be defined as resistance to three or more classes of antibiotics. The increasing incidence of antibacterial resistance and multidrug resistance (MDR) in Uropathogens has highlighted the need to find more alternative antibacterial agents from other sources such as natural products.7","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126996427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of intervention in increasing knowledge and awareness of Human Papilloma Virus (HPV) infection and HPV vaccination among graduate students in a private university, Kedah state, Malaysia 干预措施对提高马来西亚吉打州一所私立大学研究生对人乳头瘤病毒(HPV)感染和HPV疫苗接种的认识和认识的效果
MOJ Bioequivalence & Bioavailability Pub Date : 2018-07-30 DOI: 10.15406/mojbb.2018.05.00101
A. Ali, N. Y. Ping, S. Prajapati, Lim Cheng Pheng, M. Z. Iqbal, Nazer Zulfikar Ahmed
{"title":"Effect of intervention in increasing knowledge and awareness of Human Papilloma Virus (HPV) infection and HPV vaccination among graduate students in a private university, Kedah state, Malaysia","authors":"A. Ali, N. Y. Ping, S. Prajapati, Lim Cheng Pheng, M. Z. Iqbal, Nazer Zulfikar Ahmed","doi":"10.15406/mojbb.2018.05.00101","DOIUrl":"https://doi.org/10.15406/mojbb.2018.05.00101","url":null,"abstract":"Human Papilloma Virus (HPV) is the causative agent of several skin and mucosal diseases, including virtually all cases of the world’s second most common female malignancy, cervical cancer, and genital warts, the most common disease occurring in sexually active population.1 The early history of HPV infection and its relation to cervical carcinogenesis have been observed in many studies.2 However, cervical cancer development is a long process lasting 15–20 years.3 It implies, the persistence of infection with high-risk HPV type in a minority of infected women, leading to precancerous lesions (3–5 years), and eventual development of invasive cancer in the long term (>10 years).3,4","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131366535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Comparative analysis of pulmonary and respiratory medicine research in middles east region 中东地区肺与呼吸医学研究的比较分析
MOJ Bioequivalence & Bioavailability Pub Date : 2018-07-09 DOI: 10.15406/mojbb.2018.05.00099
A. Jalali, Nooshin Asadmasjedi, Shaiesteh Dehdardargahi, A. Saki
{"title":"Comparative analysis of pulmonary and respiratory medicine research in middles east region","authors":"A. Jalali, Nooshin Asadmasjedi, Shaiesteh Dehdardargahi, A. Saki","doi":"10.15406/mojbb.2018.05.00099","DOIUrl":"https://doi.org/10.15406/mojbb.2018.05.00099","url":null,"abstract":"Respiratory medicine includes a variety of extremely common diseases, such as chronic obstructive pulmonary disease (COPD), bronchial asthma, respiratory tract infections, community-acquired pneumonia (CAP) or hospital-acquired pneumonia, lung cancer, acute respiratory distress syndrome (ARDS), and pulmonary embolism. Because of the high prevalence of respiratory diseases and their associated morbidity and mortality, a considerable proportion of medical research all over the world got involved in research efforts.1","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"173 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132215836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of microbiological quality of semen of male patients with infertility at Murtala Muhammad specialist hospital kano, Nigeria 尼日利亚卡诺Murtala Muhammad专科医院男性不育症患者精液微生物质量评估
MOJ Bioequivalence & Bioavailability Pub Date : 2018-06-19 DOI: 10.15406/MOJBB.2018.05.00098
A. Muhammad, S. M. Yahaya, Agbo Eb, N. Salisu
{"title":"Assessment of microbiological quality of semen of male patients with infertility at Murtala Muhammad specialist hospital kano, Nigeria","authors":"A. Muhammad, S. M. Yahaya, Agbo Eb, N. Salisu","doi":"10.15406/MOJBB.2018.05.00098","DOIUrl":"https://doi.org/10.15406/MOJBB.2018.05.00098","url":null,"abstract":"Infertility is the inability of a sexually active, non-contraception couple to achieve spontaneous pregnancy in one year. About 15% of couples do not achieve pregnancy within one year and seek medical treatment for infertility.1 One in eight couples encounters problems in attempting to conceive a first child and one in six when attempting to conceive a subsequent child. Both sexes are more or less equally involved in infertility problem.2 Men either alone or along with their female partners, contribute to 40–45% cases of infertility.3 Furthermore, infectious aetiology involving bacteria, virus, fungi, and protozoa contribute to 15% of male factor infertility.4 Some of the microbes are acquired exogenously or endogenously and they could cause infertility in several ways: by damaging sperm motility, deterioration of spermatogenesis, altering the chemical composition of the seminal fluid by dysfunction of accessory sex glands, or by inducing autoimmune processes due to inflammation.5","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"522 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116198599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
A review on effective utilization, phytochemical compounds, pharmacological intervention of a popularly used plant for developing a new drug: Zanthoxylum armatum with reference to its anticancer activity 综述了一种常用植物花椒的有效利用、植物化学成分、药理干预等方面的研究进展，并结合其抗癌活性进行了综述
MOJ Bioequivalence & Bioavailability Pub Date : 2018-06-15 DOI: 10.15406/MOJBB.2018.05.00097
A. Barua, N. Yasmin, Elancheran Ramakrishnan
{"title":"A review on effective utilization, phytochemical compounds, pharmacological intervention of a popularly used plant for developing a new drug: Zanthoxylum armatum with reference to its anticancer activity","authors":"A. Barua, N. Yasmin, Elancheran Ramakrishnan","doi":"10.15406/MOJBB.2018.05.00097","DOIUrl":"https://doi.org/10.15406/MOJBB.2018.05.00097","url":null,"abstract":"Abbreviations: DPPH, 1,1-diphenyl-2-picrylhydrazil radical; MEZA, methanol extract of Zanthoxylum alatum; EAC, ehrlich ascites cancer; NRU, neutral red uptake; DEPA, N, N-diethyl phenyl acetamide; DEET, N, N-diethyl-m-toluamide; DMP, dimethyl phthalate; NBP, N-benzoyl piperidine; PTZ, pentylenetetrazole; ZAP, zanthoxylum alatum planispinu; ZAS, zanthoxylu alatum subtrifoliatum; MAPK, mitogen-activated protein kinases","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128719310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Biosynthesis of zinc oxide nanoparticle: a review on greener approach 纳米氧化锌的生物合成:绿色途径研究进展
MOJ Bioequivalence & Bioavailability Pub Date : 2018-06-12 DOI: 10.15406/MOJBB.2018.05.00096
Uma A maheswari, Lakshmana Prabu S, Purat chikody A
{"title":"Biosynthesis of zinc oxide nanoparticle: a review on greener approach","authors":"Uma A maheswari, Lakshmana Prabu S, Purat chikody A","doi":"10.15406/MOJBB.2018.05.00096","DOIUrl":"https://doi.org/10.15406/MOJBB.2018.05.00096","url":null,"abstract":"In last few decades the revolution of nanotechnology exhibit significant and commercial application in different fields like engineering, environmental science, agriculture, medicine, electrical and electronics, pharmaceutical, biological, biotechnology, mineral nutrition, food processing, reproduction, pharmacology applications and many more.1 The significant and increased commercial applications are owing to its nanoscale dimension, large surface area to volume ratio, unique and potential properties like electronic, magnetic, mechanical, non-linear optical performance, thermal conductivity, enhanced catalytic reactivity and chemical steadiness.2‒4 Real research and development in nanotechnology is concern with making modification in its atomic, molecular and supra-molecular levels to improve its physicochemical properties to produce desired effect.1","PeriodicalId":145593,"journal":{"name":"MOJ Bioequivalence & Bioavailability","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125910722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
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