International Journal of Scientific Research in Biological Sciences最新文献_第7页

Production Kinetics of Xylanase and Carboxy-methyl Cellulase of Schizophyllum commune in Submerged Fermentation Technique 裂叶菌深层发酵木聚糖酶和羧甲基纤维素酶生产动力学研究

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.8185

K. Majumder, Sumira Mukhia, Urmila Koirala

引用次数: 0

Regression Analysis and Docking Study of Pyrimidine Based Compounds as anti-Tuberculosis Therapeutic Agents 嘧啶类化合物抗结核治疗药物的回归分析与对接研究

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.133143

A. Parmar, M. R. Patle

{"title":"Regression Analysis and Docking Study of Pyrimidine Based Compounds as anti-Tuberculosis Therapeutic Agents","authors":"A. Parmar, M. R. Patle","doi":"10.26438/ijsrbs/v6i2.133143","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i2.133143","url":null,"abstract":"Received: 09/Apr/2019, Accepted: 19/Apr/2019, Online: 30/Apr/2019 AbstractIn the drug-design process, structure activity relationship is an important tool for estimation of biological activity of the unknown compounds. In this process, the objective is development of a relationship between structural features of molecules and the property of interest i. e. biological activity. On the basis of this relationship, the biological activity can be predicted for new candidate structures. Initially, the forty two substituted pyrimidine molecules with known biological activities were considered as known set for regression analysis model building purpose. The properties module from Datawarrior used to calculate descriptors. Structure activity model indicates that these descriptors have significant relationships with observed bioactivity. We have observed a high relationship between experimental and predicted activity values, indicating the validation and the excellent quality of the derived model. In the present study, the new substituted pyrimidine molecules are designed, optimized and their descriptors were calculated using Datawarrior modules. Then by using the Regression analysis model, their biological activities are studied as well as inhibition studies for the 1QPQ by molecular docking method are also carried out. Thus on the basis of regression analysis study and docking study of substituted pyrimidine derivatives, we can conclude that these compounds on further studies may prove to be therapeutic agent against tuberculosis.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75557354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Production and optimization of Polyhydroxybutyrate and its application in bioplastic production 聚羟基丁酸酯的生产与优化及其在生物塑料生产中的应用

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.5058

S. Kate, D. Hire, N. Pawar

引用次数: 0

Histopathological changes in liver of fish Channa punctatus (Bloch) exposure in effluents of Bhilai steel plant C.G. (India) 暴露于印度比莱钢铁厂废水中斑马鱼肝脏的组织病理学变化

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.119125

A. Mishra

引用次数: 0

Management of Varicose Vein by Hirudotherapy 喜疗治疗静脉曲张

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.4349

A. Iqbal, H. Quraishi, Huma, A. Shah, Adil Rashid, Abdur Raheem

{"title":"Management of Varicose Vein by Hirudotherapy","authors":"A. Iqbal, H. Quraishi, Huma, A. Shah, Adil Rashid, Abdur Raheem","doi":"10.26438/ijsrbs/v6i2.4349","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i2.4349","url":null,"abstract":"Received: 26/Mar/2019, Accepted: 13/Apr/2019, Online: 30/Apr/2019 Abstract— Varicose veins are veins that have become enlarged and twisted and are commonly found in legs. The calf muscles of the leg pumps. The venous blood back to the heart against the gravity. When the veins become varicose the valves do not function properly as the blood flows backwards and the veins engorge. The varicose veins are most common in the superficial veins of legs and due to high pressure while standing the veins engorging and ulceration can occur. Only ten percent of the venous blood in the legs is returned back by superficial veins, hence the surgical removal can be opted for superficial varicose veins. Other modalities of treatment included sclerotherapy, elastic stockings, leg elevation, exercise, radiofrequency ablation, endovascular laser treatment etc. In this study Hirudotherapy has been done at Regional Research Institute of Unani Medicine, Srinagar for the treatment of varicose vein and has been observed that leech relieves the symptoms of the varicosity by reducing the engorgements of the superficial leg veins and also improve the venous valvular functioning and thus helps to push the blood normally without regurgitation.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82131024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sesoanal Veriation in Primary Productivity from Nanded Region, Maharashtra 马哈拉施特拉邦南德地区初级生产力的sesananal验证

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.148150

A. Suryawanshi

引用次数: 0

Evaluation of Insecticidal and Antimicrobial Effect of Boerhavia diffusa 白花布草杀虫抑菌效果评价

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.126132

T. M. Manjima, O. G. Indusree, V. Ajitha

{"title":"Evaluation of Insecticidal and Antimicrobial Effect of Boerhavia diffusa","authors":"T. M. Manjima, O. G. Indusree, V. Ajitha","doi":"10.26438/ijsrbs/v6i2.126132","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i2.126132","url":null,"abstract":"— Boerhavia diffusa , commonly known as „Punarnava‟ in the Indian system of medicine is a perennial creeping herb found throughout the waste lands. The insecticidal activity of aqueous and acetone extracts of B. diffusa was tested against the pest insect Dysdercus cingulatus , commonly known as Red Cotton Bug. The plant extract exhibited ovicidal effect, nymphicidal effect, varying degree of moulting disruption, reduced fecundity rate along with prolonged mating period. Insecticidal property exhibited by this plant extract can be exploited in the field of Integrated Pest Management, so as to reduce the hazardous effects of chemical pesticides. The toxic principles present in the plant extract are actually secondary metabolites that are evolved as a protective measure against herbivorous animals. Antimicrobial activity of B. diffusa was also evaluated using gram negative bacteria, Pseudomonas aeruginosa and showed significant level of sensitivity to B. diffusa extracts. Thus it is evident that B. diffusa possess toxic principles having insecticidal as well as antimicrobial activity which can be employed in the field of agriculture and medicine respectively","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77935024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening of Ethnic Indian Fermented Foods for Effective Phytase Producing Lactic Acid Bacteria for Application in Dephytinization of Phytate Rich Foods 有效产植酸酶乳酸菌的印度民族发酵食品筛选及其在富植酸食品脱植酸中的应用

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.17

N. Sharma, K. Kondepudi, N. Gupta

引用次数: 4

Quantification of the minimum amount of lemon juice and apple cider vinegar required for the growth inhibition of dandruff causing fungi Malassezia furfur 柠檬汁和苹果醋抑制头皮屑真菌马拉色菌生长所需的最小量的定量

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.144147

P. Arun, Yaralagadda Vineetha, Maseera Waheed, K. Ravikanth

{"title":"Quantification of the minimum amount of lemon juice and apple cider vinegar required for the growth inhibition of dandruff causing fungi Malassezia furfur","authors":"P. Arun, Yaralagadda Vineetha, Maseera Waheed, K. Ravikanth","doi":"10.26438/ijsrbs/v6i2.144147","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i2.144147","url":null,"abstract":"The main focus of this study is to quantify the amount of lemon juice and apple cider vinegar required to inhibit the growth of lipophilic fungus, Malassezia furfur. Malassezia furfur infects the human scalp, affects hair and causes the dandruff. In this work, the antifungal effect of lemon and apple cider vinegar was investigated along with commercially available antifungal drug fluconazole. Agar diffusion method was used and the zone of inhibition was measured to quantify the amount required and also to estimate the antifungal efficacy of lemon juice and apple cider vinegar. We have used different concentration of lemon juice and apple cider vinegar such as 10%, 20%, 30%, 40%, and 50% concentrations. From our results, by observing the zones of inhibitions on the petridishes, we confirm that lemon juice and apple cider vinegar has good antifungal effect on Malassezia furfur and around 3ml to 4ml of lemon juice or apple cider vinegar diluted and made to 10ml of the solution with water would be sufficient enough to inhibit the growth of Malassezia furfur. This study justifies the use of either lemon juice or apple cider vinegar as a remedy for Malassezia furfur infected scalp and hair. Keywords— Malasezzia furfur, lemon juice, apple cider vinegar, antifungal activity","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79488637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbial analysis of water bodies near food industries 食品工业附近水体微生物分析

International Journal of Scientific Research in Biological Sciences Pub Date : 2019-04-30 DOI: 10.26438/ijsrbs/v6i2.151155

A. Pal, Astha A. Jain

引用次数: 0