International Journal of Nutrition, Pharmacology, Neurological Diseases最新文献_第2页

Quality parameters determining the buyer behavior toward purchase of bakery product (cake) 决定购买者购买烘焙产品（蛋糕）行为的质量参数

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2024-01-01 DOI: 10.4103/ijnpnd.ijnpnd_36_23

E. Lakshmi, K. S. Selvi, S. R. Fathima, Damini M

{"title":"Quality parameters determining the buyer behavior toward purchase of bakery product (cake)","authors":"E. Lakshmi, K. S. Selvi, S. R. Fathima, Damini M","doi":"10.4103/ijnpnd.ijnpnd_36_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_36_23","url":null,"abstract":"\u0000 Context: Bakery products, especially cake, has evolved from being seen as a tea-time snack to becoming a daily requirement in the typical Indian household. The quality of the ingredients in cake baking has a considerable impact on the finished product and consumers’ intention to purchase. Aims: The aims of the study was to assess the quality parameters of the flour used in baking cake and to determine buyer behavior and preferences for quality criteria in cake. Materials and Methods: The quality parameters of cake flour used in baking were experimentally determined according to IS 1979 guidelines. The characteristics of consumer behavior with regard to purchase of cake were evaluated using a questionnaire. Results: The moisture content of cake flour was 0.2% lower than IS 1979 standards (13%). The key factors in choosing the cake were appearance, tase, and soft texture, scoring the highest (1.4) on the Likert scale. The least score (0.7) was given for nutrient content. Conclusions: There was a significant difference in the purchase of cake by attributes, as the calculated value was higher than the table value.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"192 5-6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140516743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and nutritional and sensory evaluation of ragi, bajra, and white soybean incorporated adai: Traditional South Indian food for pregnant women with micronutrient deficiency 掺入了胡麻、巴豆和白大豆的阿达伊的开发、营养和感官评估：为微量营养素缺乏症孕妇提供的南印度传统食品

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2024-01-01 DOI: 10.4103/ijnpnd.ijnpnd_75_23

Pratheesha Ilangovan, Aruna Subramaniam, R. Vembu, Silambu Selvi

{"title":"Development and nutritional and sensory evaluation of ragi, bajra, and white soybean incorporated adai: Traditional South Indian food for pregnant women with micronutrient deficiency","authors":"Pratheesha Ilangovan, Aruna Subramaniam, R. Vembu, Silambu Selvi","doi":"10.4103/ijnpnd.ijnpnd_75_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_75_23","url":null,"abstract":"\u0000 Background: Pregnant women have increased nutritional needs to support the growth of the baby, placenta, and maternal tissues. Inadequate dietary intake of these essential nutrients can lead to maternal-fetal complications. Hence, this study has developed a micronutrient-rich adai to educate and encourage pregnant women to incorporate it into their regular diet. Aims: The aim of this study was to develop a micronutrient-rich adai using millets, grains, green leaves, and spices and to evaluate its sensory characteristics and nutritional qualities. Methods: A micronutrient-rich adai was prepared with four food groups: (1) cereals and millets, (2) legumes and grains, (3) green leaves, and (4) spices in three different formulations: type I, type II, and type III, with the ratios of [1,2,3+4] are 50:30:20, 40:30:30, and 40:20:40, respectively. Sensory evaluation was conducted among 20 pregnant women using 9-point hedonic scales for color, flavor, taste, texture, and overall acceptability. The nutritional analysis was performed using Association of Official Analytical Collaboration (AOAC) (2016) methods. Statistical analysis was done by using SPSS version 21. Results: Type I adai was well accepted, with a mean score of 36.85, while type II (27.65) and type III (28.5) scored lower. One-way analysis of variance showed a significant difference in mean scores, with type I adai being statistically significant (P < 0.05). Nutrient analysis indicated adequate amounts of iron, calcium, and vitamin D. Conclusion: The study revealed that the type I combination of adai was found to be more palatable compared to the other two types and rich in calcium and iron. This suggests that mothers can be motivated to incorporate it into their diet.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"40 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140524119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acceptability and feasibility of delivering family intervention for caregivers of patients with schizophrenia in Egypt 为埃及精神分裂症患者的照顾者提供家庭干预的可接受性和可行性

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2024-01-01 DOI: 10.4103/ijnpnd.ijnpnd_70_23

Rasha Wahid, E. Lazarus, A. Amirtharaj

{"title":"Acceptability and feasibility of delivering family intervention for caregivers of patients with schizophrenia in Egypt","authors":"Rasha Wahid, E. Lazarus, A. Amirtharaj","doi":"10.4103/ijnpnd.ijnpnd_70_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_70_23","url":null,"abstract":"\u0000 Background: In Egypt as elsewhere, patients with schizophrenia and their families confront unique obstacles. This study examined the views of important stakeholders’ on the feasibility, approval, and obstacles of family intervention programs for schizophrenia in Egypt to address these issues. Objective: The aim of the study was to investigate the perspectives of stakeholders regarding the feasibility, acceptability, and obstacles associated with providing family intervention for schizophrenia in Egypt. Methods: The research took place at El-Maamoura Hospital in Alexandria and included a total of 37 participants. These participants were divided into seven focus groups, with 25 individuals being health professionals and the remaining 12 individuals being caregivers. Concurrently, data collection and analysis were carried out using the qualitative research method, employing the framework analysis to process the transcripts. Results: The participants highlighted the importance of families feeling accepted and well-informed regarding the nature of the illness. In conclusion, the participants suggested making changes to the intervention’s content by incorporating details about the illness, providing emotional support, and including culturally appropriate coping mechanisms. Conclusion: In conclusion, it is determined by the study that before implementing family intervention for schizophrenia, it is crucial to make cultural adjustments to ensure its acceptability. The findings of the study offer valuable insights for the development and execution of family intervention programs for schizophrenia in Egypt. Implication for Clinical Practice: It is crucial to culturally adapt a modified family interventions to cater to the cultural requirements of families and healthcare professionals in Egypt, as this could potentially result in improved outcomes for patients diagnosed with schizophrenia and their families.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"1 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140527335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Cross-Sectional Study to Determine the Prevalence and Predictors of Depression and Anxiety in Type 2 Diabetes Patients in South India 确定南印度 2 型糖尿病患者抑郁和焦虑患病率及预测因素的横断面研究

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2024-01-01 DOI: 10.4103/ijnpnd.ijnpnd_83_23

Prasanth Subramanian, Venkataraman Prabhu, A. Ramachandran, J. Kumar

{"title":"A Cross-Sectional Study to Determine the Prevalence and Predictors of Depression and Anxiety in Type 2 Diabetes Patients in South India","authors":"Prasanth Subramanian, Venkataraman Prabhu, A. Ramachandran, J. Kumar","doi":"10.4103/ijnpnd.ijnpnd_83_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_83_23","url":null,"abstract":"Diabetic patients with depression or anxiety are more likely to develop diabetic complications and have a lower quality of life. The aim of the study is to determine the prevalence of depression and anxiety among type 2 diabetic patients and to identify the associated factors. A cross-sectional, observational study of type 2 diabetes mellitus outpatients, with diabetes-related conditions who attended the hospital from January to April 2023, was conducted by interviewing them using the Patient Health Questionnaire-9 for depression and Generalised Anxiety Disorders-7 for anxiety. Descriptive statistics, bivariate analysis, and multivariant regression were performed for statistical analysis. Out of 450 type 2 diabetic patients, 90% were between ages 30 and 45, 50.2% were male, 60% were living in rural areas, and 76.5% literate; most of them belong to the upper middle class (64%) and they live in joint family (32.7%). Depression and anxiety were observed among 65.3% and 62.4% of type 2 diabetic patients, respectively. When observing the severity, 47.8% of patients had mild depression, and 38.7% had minimal anxiety. Age group, socioeconomic status, treatment type, and years of diabetes were found to be factors associated with depression and family type is associated with anxiety. Hospitalized diabetics have higher depression and anxiety rates for multiple reasons. Therefore, diabetes management programmes should include regular depression and anxiety screenings to quickly identify and treat high-risk patients in healthcare facilities.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140515719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection and Classification of Diabetic Retinopathy Using Inception V3 and Xception Architectures 使用 Inception V3 和 Xception 架构检测和分类糖尿病视网膜病变

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2024-01-01 DOI: 10.4103/ijnpnd.ijnpnd_76_23

V. Sathiya, B. Shenbagavalli, V. Nirupa, K. Subramani

{"title":"Detection and Classification of Diabetic Retinopathy Using Inception V3 and Xception Architectures","authors":"V. Sathiya, B. Shenbagavalli, V. Nirupa, K. Subramani","doi":"10.4103/ijnpnd.ijnpnd_76_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_76_23","url":null,"abstract":"Patients with diabetes usually develop a condition called diabetic retinopathy (DR), resulting from retinal damage. This impairment usually happens when the glucose levels in the blood are elevated, finally causing a blockage in the blood vessels that feed a part of the eye called the retina and finally severing it from the blood supply. Therefore, the eye attempts to produce fresh blood cells. But these cells are either poorly developed or weak. So, it can be leaked out easily. Hence, to lessen the severe effects of this disease, these patients must be diagnosed as soon as possible. Earlier, a number of approaches were put forth to recognise this illness using machine learning algorithms, image processing, and other techniques. The diagnosis process of this disease involves pre-processing of coloured images of the fundus, extraction of clinical features and classification of retinopathy. In this research, fundus photography of the retina is utilised to accelerate the detection of various kinds of retinopathy caused by diabetes based on convolutional neural network (CNN) pre-trained transfer learning algorithm. Inception V3 and Xception are used in this model to determine and categorise diabetic retinopathy, respectively. As a result, people with this disease can lower their risk of exposure to permanent blindness.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"36 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140526429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Sodium Levels in Different Brands of Edible Salts by Flame Photometer 用火焰光度计分析不同品牌食用盐中的钠含量

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2024-01-01 DOI: 10.4103/ijnpnd.ijnpnd_67_23

Mullaicharam Bhupathyraaj, Salha Said Rabia Al Salty, Mohammad Al-Ghazali, N. Halligudi

{"title":"Analysis of Sodium Levels in Different Brands of Edible Salts by Flame Photometer","authors":"Mullaicharam Bhupathyraaj, Salha Said Rabia Al Salty, Mohammad Al-Ghazali, N. Halligudi","doi":"10.4103/ijnpnd.ijnpnd_67_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_67_23","url":null,"abstract":"Sodium is a key element for all living things, mainly animals, some plant species, and humans. In animals, sodium ions are necessary for the regulation of blood and body fluids, the transmission of nerve impulses, heart activity, and certain metabolic functions. Sodium is the chief cation in the extracellular compartment of an animal body. Sodium plays a vital role not only in the human body but also in various food types. Salt, also known as sodium chloride, is about 40% sodium and 60% chloride. It flavors food and is used as a binder and stabilizer. The sodium content in different brands of edible salts can be analyzed using flame photometry. Flame photometry, also called flame atomic emission spectrometry, is a branch of atomic spectroscopy in which the species examined in the spectrometer are in the form of atoms. The samples used for analysis are junk foods, which have become a common trend among all generations. A total of 13 brands were analyzed for iodine content. From that, two commonly used brands were selected and analyzed for estimating the sodium and potassium contents in them by flame photometry. The analysis helps in creating awareness among all generations to reduce the sodium intake in order to prevent problems like hypertension, hyponatremia, hypernatremia, and associated medical complications in the future.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"185 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140516761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and characterization of andrographolide: Albumin nanoparticles and their anticancer activity in HeLa cancer cell line 穿心莲内酯的合成和表征：白蛋白纳米颗粒及其在 HeLa 癌细胞系中的抗癌活性

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2024-01-01 DOI: 10.4103/ijnpnd.ijnpnd_85_23

Lavanya S.K., Shantanu Patil, Sundaresan Sivapatham

{"title":"Synthesis and characterization of andrographolide: Albumin nanoparticles and their anticancer activity in HeLa cancer cell line","authors":"Lavanya S.K., Shantanu Patil, Sundaresan Sivapatham","doi":"10.4103/ijnpnd.ijnpnd_85_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_85_23","url":null,"abstract":"Nanoparticles are frequently employed to control the delivery of drugs and various growth factors to tissues/cells. Nanocarriers, in diverse formulations, have the potential to transport both synthetic and natural anticancer therapeutic drugs. Andrographolide, a diterpenoid extracted from Andrographis paniculata, possesses robust antioxidant, anti-inflammatory, anticancer, and antiviral effects. The inhibition of cervical cancer can be achieved by supplementing with bioactive molecules that decrease the proliferation and differentiation of cervical cancer cells while promoting cell death. This study explores the in vitro antiproliferative efficacy of andrographolide on cervical cancer cells, assessed through a cytotoxicity assay in human cervical cancer cells. The results demonstrated increased activity of andrographolide in a dose- and time-dependent manner. The andrographolide-albumin nanoparticle (ANP) was synthesized using the coacervation process. X-ray diffraction and Raman analysis of ANP revealed the amorphization of andrographolide, a favorable characteristic for drug delivery applications. Additionally, Fourier Transform Infrared (FTIR) analysis illustrated the drug structure and the stretching of bands in the synthesized ANP. High-resolution scanning electron microscopy unveiled spherical granules with nanoparticle sizes ranging from 100 to 200 nm. Furthermore, the anticancer activity of andrographolide-ANPs was observed in the HeLa cancer cell line. The synthesis and characterization of andrographolide-ANPs were undertaken for potential therapeutic applications.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"325 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herbomineral form of Eclipta alba (HMEA) improves age-related dementia by increasing memory performance in animal models: An in vivo approach to investigate the multitherapeutic potential of antioxidant-based Ayurvedic drugs Eclipta alba（HMEA）的草药形式可通过提高动物模型的记忆力来改善与年龄有关的痴呆症：研究以抗氧化剂为基础的阿育吠陀药物的多种治疗潜力的体内方法

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2023-11-30 DOI: 10.4103/ijnpnd.ijnpnd_52_23

Meher Nisha Abubakkar, Abir Biswas, Anitha Rathinam, Kumar Surya, Jenani Murugesan, Ajitha Sherlin, K. S. Jayachandran, Giri Prashanth, M. Anusuyadevi

{"title":"Herbomineral form of Eclipta alba (HMEA) improves age-related dementia by increasing memory performance in animal models: An in vivo approach to investigate the multitherapeutic potential of antioxidant-based Ayurvedic drugs","authors":"Meher Nisha Abubakkar, Abir Biswas, Anitha Rathinam, Kumar Surya, Jenani Murugesan, Ajitha Sherlin, K. S. Jayachandran, Giri Prashanth, M. Anusuyadevi","doi":"10.4103/ijnpnd.ijnpnd_52_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_52_23","url":null,"abstract":"Dementia is a consequential event due to neurodegeneration, which is a prevalent aspect of aging and other diseases associated with neuropathological conditions. The main contributor to dementia is the depletion of neurons in cognitive centers that results in cognitive decline. Cellular damage and apoptosis can occur due to excessive oxidative stress and reduced antioxidant levels. Epidemiological research provides valuable insights into dementia, but current treatments primarily focus on alleviating symptoms rather than addressing the root cause. Both modern and traditional medicines recognize the importance of maintaining cellular antioxidant levels and reduction in amyloid beta aggregation, often relying on natural sources for support. The identification of herbal plants with abundant pharmacologically active secondary metabolites shows promise in the treatment of dementia. Eclipta alba is an ancient traditional herb that elicits nootropic effects. This study reports that the herbomineral form of E. alba (HMEA) constitutes pharmacologically active metabolites and enhances memory and learning in 9- to 12-month-old albino wistar rats. Interestingly, HMEA enhanced learning and memory in adult rats with no significant toxicity, and found to stabilize lipid profile levels in animal models. Histopathological studies of animals showed that HMEA enhanced overall cytoarchitecture of granular cell layer in the hippocampus. It depicts improved cellular morphology, arrangement, and density in the hippocampal region. Taken together, the current study proves HMEA to be an efficient neuroprotective agent in treating age-related dementia.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"23 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139205846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An ensemble of ResNet model for classification of Parkinson disease 用于帕金森病分类的 ResNet 模型集合

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2023-11-30 DOI: 10.4103/ijnpnd.ijnpnd_22_23

M. Mahendran, R. Visalakshi

引用次数: 0

Vitamin B-12, Homocysteine, and Hematological Parameters in Ischemic Stroke Patients 缺血性脑卒中患者的维生素 B-12、同型半胱氨酸和血液学参数

International Journal of Nutrition, Pharmacology, Neurological Diseases Pub Date : 2023-10-01 DOI: 10.4103/ijnpnd.ijnpnd_50_23

J. Isaac, Vijayashree Raghavan

{"title":"Vitamin B-12, Homocysteine, and Hematological Parameters in Ischemic Stroke Patients","authors":"J. Isaac, Vijayashree Raghavan","doi":"10.4103/ijnpnd.ijnpnd_50_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_50_23","url":null,"abstract":"Background: A cerebrovascular accident or stroke is one of the leading causes of disability and death in the world. Several risk factors have been detected and extensively studied and are part of preventive strategies. Emerging risk factors for ischemic that have recently acquired interest are vitamin B-12 and homocysteine levels. A study has been conducted in a tertiary hospital in Chennai to evaluate the levels of vitamin B-12, homocysteine, and hematological variables. Aims: The objective of the study was to estimate the serum levels of homocysteine and vitamin B-12 in patients with ischemic stroke and transient ischemic attack and to analyze hematological parameters, including complete blood counts and peripheral smear and correlate with vitamin B-12. Materials and Methods: A total of 80 individuals with either ischemic stroke or transient ischemic attack were included in the study. Vitamin B-12, homocysteine, complete blood counts, and peripheral smear were analyzed for the patients. Results: Either frank or subclinical vitamin B-12 deficiencies were noted in 59 (73.8%) of the study population. Fifty-seven (71.2%) of the study population had elevated homocysteine. Fifty (62.5%) had a high neutrophil-to-lymphocyte (N:L) ratio and 52 (65%) had elevated red cell distribution width. Conclusion: High homocysteine levels are prevalent among ischemic stroke patients and this elucidates that homocysteine has a role in the thrombus formation and is a risk factor for the development of the stroke. It was also noted that vitamin B-12 deficiency, either frank or subclinical, is prevalent among these patients and can be a target for supplementation strategies.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"10 1","pages":"250 - 254"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139329011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0