International Journal of Life Science Research Archive最新文献

{"title":"Study on the effectiveness of an air treatment tool that combines filtration and photocatalysis","authors":"Simone Pescarolo, Dario Russignaga, Luca Maria D’apuzzo, Matteo Nazzario, Irene Borgini, Sara Beneventi, Giorgio Gilli","doi":"10.53771/ijlsra.2023.4.1.0045","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0045","url":null,"abstract":"The microbiological quality of air in working environments is a very current topic. This study aims to evaluate the effectiveness of a machine equipped with EPA filters and photocatalytic activity. This type of treatment combines a physical action with a chemical activity. The latter occurs thanks to the production of reactive oxygen species (ROS), responsible for a marked bactericidal activity. The search for new sanitization techniques pushes companies to invest to improve the quality of work of their employees. Many tools are sold on the market, but it is important to check their actual effectiveness. Monitoring the activity of air treatments is always very complex, due to the variability and heterogeneity of airborne microorganisms. This study was conducted in a typical working environment, to better simulate normal conditions of use. To avoid potentially pathogenic contamination, microorganisms typically recountable in the air matrix were not used, but the species of bacteria Lactococcus lactis was used. These microorganisms are also naturally present in the outdoor environment and represent a population of bacteria that could potentially cause indoor air pollution. The results confirm the effectiveness of this type of treatment. It was not possible to determine the impact of the catalytic feature installed.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"12 Dermatol Sect 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87542763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of the incorporation of cashew meal (Anacardium occidental) in feed on the laying performance of hens (ISA Brown) in Côte d'Ivoire","authors":"Ouattara Abdoulaye, Diomande Masse, Fofana Daouda","doi":"10.53771/ijlsra.2023.4.1.0043","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0043","url":null,"abstract":"In Côte d'Ivoire, the increase in the price of protein raw materials makes poultry production too costly. This study was carried out to develop new sources of vegetable protein (cashew cake) for feeding laying hens during the laying period. For this, 180 19-week-old ISA Brown hens were used. They were housed in 4 boxes, 45 each. These constituted batches were fed T0 (control), T1 (100% cashew meal as main vegetable protein source), T2 (50% cashew meal) and T3 (95 % cashew meal). Bromatological analysis of the feeds revealed an excellent nutrient content. Feed intake, average number of eggs laid, average cumulative egg weight, feed conversion ratio, and egg laying rate were significantly (p<5%) influenced by the formulation. Cashew meal-based feeds improved egg-laying parameters but not significantly. The food supply for chickens was 93.16 ± 11.35 g / d /chicken (T0), 68.38 ± 13.67 g / d / chicken (T1), 85.67 ± 11.23 g / d / chicken (T2) et 65.88 ± 10.38 g / d / chicken. The number of eggs laid was 29.13 ± 8.77 eggs / d (T0), 11.89 ± 7.03 eggs / d (T1), 24.80 ± 7.85 eggs / d (T2) and 13.51 ± 7.57 eggs / d (T3). The average cumulative egg weight was 1645.86 ± 538.63 g / d (T0), 688.36 ± 445.41 g / d (T1), 1356.83 ± 449.62 g / d (T2) and 776.63 ± 467.51 g / d (T3). The consumption index was 3.84 ± 5.53 (T0), 7.26 ± 11.31 (T1), 4.16 ± 6.19 (T2) and 5.13 ± 8.48 (T3). Laying rate was 64.73 ± 19.51% (T0), 26.42 ± 15.64 % (T1), 55.12 ± 12.46% (T2) and 30.03 ± 16.82% (T3). The incorporation of cashew meal in the feed of laying hens as the main source of protein should allow for a variety of protein raw materials to correct any difficulties encountered by some table egg producers in Côte d’Ivoire.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74663408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Candidemia diagnosed within the Hassan II University Hospital in Fez","authors":"K Lemhouer, J Elamouri, S Adadi, Z.Tlamcani","doi":"10.53771/ijlsra.2023.4.1.0042","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0042","url":null,"abstract":"Introduction: Candidemia are yeast infections of the candida type that are relatively common in intensive care and are burdened with a high mortality rate that has not decreased for decades. The aim of this work is to determine the frequency of candidaemia and to identify the epidemiological profile of the Candida species most implicated in these infections. Materials and methods: This is a descriptive retrospective study over a period of 5 years and 7 months, spanning from January 2017 to July 2022, and involving all blood cultures of patients hospitalized at the CHU Hassan II in Fez. The samples were inoculated into Mycosis IC/F bottles and incubated for 7 days in the BD Bactec® automaton. 37°C. The identification of yeasts was based on morphological, phenotypic, biochemical and sometimes immunological criteria. This identification is followed by the realization of an antifungigram. Results: During the study period, 145 blood cultures were performed, 42 of which were positive for candida. 69% of patients were hospitalized in intensive care. The female sex (52.3%) was more affected than the male sex (47.6%) with an average age of 31 years. The frequency of candidaemia is estimated at 28.9%. They were mainly caused by Candida non albicans (64.2%) including Candida glabrata 33.3%, Candida tropicalis 29.6%, Candida parapsilosis 20%, Candida krusei 18.5% and Candida lusitaniae 3.7%. While Candida albicans was positive in 15 patients. Sensitivity to amphotericin B and fluconazole was 89% and 70% respectively. Conclusion: Candidemia is a frequently fatal opportunistic infection. The proper use of antifungals is essential to better understand changes in the distribution of Candida species and limit the emergence of resistance","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80007137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biphenotypic acute leukemia","authors":"K Lemhouer, J Elamouri, M. Braoul, I. tlamçani, M. Amrani Hassani","doi":"10.53771/ijlsra.2023.4.1.0037","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0037","url":null,"abstract":"Biphenypic leukemia (BAL) is defined by the presence on the same blastic cells of markers belonging to at least two different lines. The incidence is estimated at less than 5% of acute leukemia cases, even if there are disparities in the literature. The morphological aspects of blast cells are variable, aspects of lymphoblasts in 1/3 cases or myeloblasts in other cases. Blast cell flow cytometry distinguishes BAL with co-expression of lymphoid and myeloid markers (L+M) or myeloid markers with lymphoid markers (M+L). BAL with lymphoid markers B and T (B+T) are rarer. Conventional cytogenetic examination makes it possible to highlight more frequently in the BAL type anomalies t(9;22)(q34;q11) in adults, t(12;21)(p13;q22) in children or abnormalities in 11q23, more rarely other cytogenetic abnormalities. We note the observation of two cases of acute leukemia with their immunophenotypic profile in order to highlight the difficulty of classifying certain acute leukemia with a mixed phenotype and highlight the complementarity of biological analyses for characterization and management of these leukemias.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79618281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross sectional survey to assess the effectiveness of HT KOT among the Ayurveda medical practioners across India","authors":"Anoop A K, Ramesh.P. R, K. P. Nair, P. Venugopalan, T. Jayaraj","doi":"10.53771/ijlsra.2023.4.1.0035","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0035","url":null,"abstract":"Hypertension (High blood pressure) is ranked as the third most important risk factor for attributable burden of disease in south Asia. Hypertension (HTN) exerts a substantial public health burden on cardiovascular health status and healthcare systems in India. Overall prevalence for hypertension in India is 29.8% (95% confidence interval: 26.7–33.0). Significant differences in hypertension prevalence were noted between rural and urban parts of the population. [27.6% (23.2–32.0) and 33.8% (29.7–37.8); P = 0.05) It is estimated that at least one in four adults in India has hypertension, but, only about 12% of them have their blood pressure under control. India has set a target of 25% relative reduction in the prevalence of hypertension (raised blood pressure) by 2025. HT Kot tablet is used in the treatment and management of hypertension. HT Kot contain 3 ingredients namely Jadamamsi (Nardostachys jatamansi), Sarpagandha (Raufolia serpentine) and Ruraksha (Elaeocarpus sphaericus). It is observed that HT kot helps in improving the cardiovascular functions. It is also observed that HT Kot helps to reduce nervousness and anxiety. A descriptive cross sectional survey was done among Ayurvedic physicians in different parts of India. Out of 128 physicians, 86 (67.18%) physicians having more than 10 years of experiences. Survey reveals that majority of the physicians (more than 75%) opined that HT kot is effective in stage 1&2 hypertension. The added effect of HT Kot is that it helps to improve the quality of sleep, reduce hyperactivity in children and anxiety. Majority of the respondents opined that the ideal time of administration of HT kot is after breakfast and dinner. The combination therapy with HT Kot is good in many conditions like hyperactivity, nervousness, hyperacidity and fatigue. The present article is based on the survey conducted among the Ayurvedic practioners in different parts of India, to assess the effectiveness and additional benefits observed with HT kot.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90119096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A brief review of medicinal plants used by the Naga tribes of Nagaland, India","authors":"Aruku Dazo Vadeo","doi":"10.53771/ijlsra.2023.4.1.0025","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0025","url":null,"abstract":"This review examines the use of 20 indigenous medicinal plants by the Naga tribes of northeast India. Each Naga tribe has its unique culture and traditions, and their medicinal practices vary. The review focuses on the phytochemical constituents, pharmacological and biological activities of these plants, as well as their traditional uses. The study found evidence supporting the efficacy of these plants and confirming traditional practices, but further investigation is necessary to fully understand their chemical components and biological effects for potential drug development.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90813716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of antibiotics utilization in respiratory tract infections in teaching hospital","authors":"KALYANI B BIRADAR, UMESH MITTE","doi":"10.53771/ijlsra.2023.4.1.0024","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0024","url":null,"abstract":"Background: Antibiotics are the main key drugs for treatment of respiratory tract infections (RTI) of both in upper respiratory tract infections (URTI) and lower respiratory tract infections (LRTI), and are among the most commonly prescribed drugs in adults. The caution use for anti-microbial agents (AMAs) is very important as their serious side effects, drug resistance and cost effectiveness can be life threatening. “In general drug utilization studies are carried out to identify appropriate usage of drugs in terms of medical, social and economical aspects. Objectives: A prospective observational study was carried out for a period of nine months between Januarys to September 2018. The information was collected from the Department of General Medicine and Pulmonology Basaveshwara general and teaching hospital Kalaburgi (India). Materials and methods: The prescription is chosen based on the inclusion criteria and the treatment follow-up until the patient discharge. During the study period the inpatient case records will be reviewed, which include antibiotics used and their dosage schedule, route of administration, dosage frequency & strength, date of discontinuation, generic name & bacteriological investigation. The information will document in the patient profile form. The data were analyzed by using online drug information like microdex, mediscap and data were present percentage calculation. Results: The results showed that out of 80 patients enrolled in the study 39 (48%) were given both IV route and oral route, 38 (47%) were given only IV route, 3 (4%) were given by oral route of antibiotics. In our study found that the combination of antibiotics Ceftriaxone, Amoxicillin with Clavunate, Pipericillin with Tozabactum were found to be commonly prescribed. In 42 patients (52%) are prescribed on diagnostic report were as in 38 patients (47%) prescribed without diagnosis of RTIs. Conclusion: The 20% of studied prescriptions founded prophylactic use of antibiotics combination. Thus special measures are imperative for their rational usage to prevent emergence of antibiotic resistance, serious side effects and cost effective treatment of poor economical patients. It can be concluded that it is mandatory to prepare suitable clinical guidelines for antibiotic prescriptions and usage rather than prescribing multiple and combination antibiotics.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84841706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception prevalence of the relationship between PID and infertility amongst women of reproductive age: A Nigerian study","authors":"Owhonda G, Eli S, Okagua KE, Ocheche U, Alali Dan-Jumbo, Nonye-Enyidah EI, Iwo-Amah RS, Wakama IE, Inimgba NM","doi":"10.53771/ijlsra.2023.4.1.0020","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0020","url":null,"abstract":"There is an established relationship between Pelvic Inflammatory Disease (PID) and infertility. These two entities are of public health concern globally due to the burden on reproductive health. Evidence has shown the relationship between PID and infertility to be between 9 and 85% from various regions of the world. Aim: To determine the perception prevalence of the relationship between PID and infertility amongst women of reproductive age in Rivers State Nigeria. Method: It was a cross sectional study of women of reproductive age who attended enlightenment campaign by the Mother and Baby Care Global Foundation. Information were coded and analysed using SPSS version 25. Results: Two hundred and fifty (250) subjects were enrolled for the study. The mean age was 24 ± 4 years. One hundred and fifteen (46%) were between ages 20 – 29 years, 30 – 39 years represented 85 (34%) of the subjects, 50(20%) were between ages 40 – 49years. Subjects aware of PID and infertility were 74 (30%) and 113 (45%) respectively. The relationship between PID and infertility was 25 (10%). For the educational status of the subjects tertiary level of education comprised of 200 (80%) while 50 (20%) had. Conclusion: This study revealed the perception prevalence of the relationship between PID and infertility as 10%. This indeed worrisome taking into cognisance the devastating effect of PID on human reproduction. Enlightenment programme is highly recommended to prevent its negative consequences PID on fertility.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74478028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study on the rural-urban employment status of low-income individuals (B40 group) with hypertension in Malaysia: The RESPOND study","authors":"Nafiza Mat-Nasir, Mohamad-Rodi Isa, Farnaza Ariffin, Mazapuspavina Md Yasin, Fadhlina Abd-Majid, Benjamin Palafox, Martin McKee","doi":"10.53771/ijlsra.2023.4.1.0027","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0027","url":null,"abstract":"Background: There is a relationship between poor people being more likely to develop non-communicable diseases. This study was conducted to compare the socio-demographic differences mostly looking at the employment status between urban and rural low-income individuals (B40 group) with hypertension in Malaysia. Material and Methods: The communities were selected from rural and urban populations in four peninsular states. Following a multistage sampling approach, communities in each stratum were selected according to probability proportional to the size and identified based on national census data. Households were randomly selected. Eligible individuals were those aged between 35 and 70 years old, self-reported or identified as hypertensive at screening. Informed consent was taken. A survey using validated questionnaires was conducted. Results: A total of 611 respondents were involved in this study. 308 (49.6%) were from urban and 308 (50.4%) were from rural areas. The characteristics of the sociodemographic from both locations were comparable (p>0.05) except for the job description (p<0.001). There were around 50% worked full-time employment and 75.8% disagree that they lost their job within 6 months. There was no significant difference in household income between urban and rural respondents (p=0.550). Unfortunately, there was only a third of them received regular cash transfers, subsidies or payments through B40 Malaysia and 14.0% of the respondents had no more income after deducting taxes. Conclusion: There were not so many differences in the characteristics of the respondents in both locations except for the job description. It might be helpful for the government in the formulation the policies to reduce the poverty and assist this population to receive medical treatment to control their hypertension.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79312473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-trauma care in the Intensive Care Unit and the role of the nurse: A literature review","authors":"Panagiota Garoufali, Christina Karagianni, Areti Panoutsakopoulou, Alexandros Mihopoulos","doi":"10.53771/ijlsra.2023.4.1.0036","DOIUrl":"https://doi.org/10.53771/ijlsra.2023.4.1.0036","url":null,"abstract":"Introduction: Multiple traumas occupy a significant part of the staff in the Intensive Care Unit (ICU), as multi-injured patients almost always require intensive care. These patients are distinguished, depending on the cause and type of injuries, in specific categories such as injuries, bleeding etc. During their stay in the ICU they may experience complications that need immediate treatment. The role of the nurse is mainly focused on the constant vigilance and the correct hierarchy of interventions. Aim: The purpose of this literature review is to investigate the care of the multi-injured in ICU and the role of the nurse on it. Method: A bibliographic review was performed on the sites 'PubMed', 'google scholar', 'Scopus' and 'open-archives', with the keywords: 'multi-injured', 'multi-injured in ICU', 'multi-injured care in ICU' , \"the role of the nurse in ICU\" and \"patient with trauma in ICU\", for the years 2007-21. A total of 28 articles were used, in English and Greek language. Results: An observational study in Greece (2011) showed that the most common cause of admission to ICUs was road accidents, while a study in China (2014-15) showed that acute intracerebral hemorrhage and brain injury were the most common causes of death. A study in South Korea (2010-15) found that the most common complication in multiple injuries in ICU was respiratory-related pneumonia (VAP), while in another study in the Netherlands (2013-18) 24.6% developed delirium/confusion within the ICU. Meta-analyses in China (2018) and Australia (2016) and a literature review in Canada (2016) showed that early enteral nutrition reduces complications, mortality, and length of stay in the ICU. According to a cohort study in USA (2012), early mobilization of the multi-injured also contributes to the reduction of complications. An observational study in England (2012-15) showed that surgery reduces mortality, while in a prospective study in Brazil (2010-11) the workload of nurses in ICUs with multiple injuries was high and correlated with various factors. Finally, in a contemporary study in Greece (2019) it was observed that 80% of patients in the ICU had experienced positive experiences from the nursing staff. Conclusions: In recent years, studies have been conducted internationally on the prevention, treatment and care of multiple injuries in ICUs. It is proposed to further strengthen the role of nurses, mainly through the institutionalization of protocols and training programs, to improve patient prognosis and reduce health costs in hospitals.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"198 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80006482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}