International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association最新文献

筛选
英文 中文
The dynamics of stigma in leprosy. 麻风病的病耻感。
M L Heijnders
{"title":"The dynamics of stigma in leprosy.","authors":"M L Heijnders","doi":"10.1489/1544-581X(2004)72<437:TDOSIL>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<437:TDOSIL>2.0.CO;2","url":null,"abstract":"<p><p>Leprosy in Nepal is a stigmatizing disease. This paper explores the different coping strategies employed by people affected by leprosy to manage stigma. It is based on a qualitative study conducted in the eastern part of Nepal. It will show that a difference exists between experienced stigma and the anticipation of stigma. Both types of stigma result in different coping strategies. In managing stigma people go through different phases. This paper will show that stigma is a dynamic process, and I will elaborate on the concealment cycle, as developed by Hyland, to produce a more detailed understanding of the stigmatization process in Nepal. Doing so, it highlights the importance of a mutual concealment phase and the importance of triggers to exposure and discrimination. Changing from one phase to a subsequent phase in the stigmatization process is always triggered. It highlights further, that even within the same culture and even the same village, social differentiation makes a significant difference on the impact of stigma and the coping strategies employed in managing stigma. Stigma enforces already existing inequalities in social class, gender, and age.</p>","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"437-47"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24996142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 78
The relapse rate in MB leprosy patients treated with 2-years of WHO-MDT is not low. 接受2年WHO-MDT治疗的MB麻风患者复发率不低。
Robert H Gelber, Victoria F Balagon, Roland V Cellona
{"title":"The relapse rate in MB leprosy patients treated with 2-years of WHO-MDT is not low.","authors":"Robert H Gelber,&nbsp;Victoria F Balagon,&nbsp;Roland V Cellona","doi":"10.1489/1544-581X(2004)72<493:TRRIML>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<493:TRRIML>2.0.CO;2","url":null,"abstract":"<p><p>A group of multibacillary patients is clearly at high risk for relapse following 2-yr WHO-MDT. Relapse is largely confined to BL or LL patients with a high BI initially, and occurs long after the discontinuation of therapy. This important group of patients at risk for treatment failure presents several important issues: the need to identify those at risk and the operational requirements needed for their long term follow-up. Also, this group of patients might well benefit from an alternative antimicrobial regimen from the outset, as well as upon relapse.</p>","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"493-500"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24995434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 58
A mutation at codon 516 in the rpoB gene of Mycobacterium leprae confers resistance to rifampin. 麻风分枝杆菌rpoB基因密码子516的突变使其对利福平产生耐药性。
Liangfen Zhang, Masako Namisato, Masanori Matsuoka
{"title":"A mutation at codon 516 in the rpoB gene of Mycobacterium leprae confers resistance to rifampin.","authors":"Liangfen Zhang,&nbsp;Masako Namisato,&nbsp;Masanori Matsuoka","doi":"10.1489/1544-581X(2004)72<468:AMACIT>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<468:AMACIT>2.0.CO;2","url":null,"abstract":"<p><p>A missense mutation at codon 516 in the rpoB gene of Mycobacterium leprae conferring rifampin resistance was confirmed by the correlation between sequencing results and mouse footpad assay. The isolate was obtained from a relapsed lepromatous leprosy patient. This is the first report on the complete concordance between the mutation located at codon 516 in the rpoB gene and the corresponding resistance to rifampin in leprosy. The novel profile of mutation in the rpoB gene will contribute to the comprehensive understanding of rifampin resistant patterns and offer a useful tool for developing simple and rapid drug susceptibility testing approaches, which would promise more effective and successful control of leprosy.</p>","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"468-72"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24995426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Regarding classification of leprosy. 关于麻风的分类。
Sunil Deepak
{"title":"Regarding classification of leprosy.","authors":"Sunil Deepak","doi":"10.1489/1544-581X(2004)72<491a:RCOL>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<491a:RCOL>2.0.CO;2","url":null,"abstract":"","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"491"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24995432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparison of economic aspects of hospitalization versus ambulatory care in the management of neuritis occurring in lepra reaction. 麻风反应中发生的神经炎的住院治疗与门诊治疗的经济方面的比较。
Ravi H N, Renu George, Elizabeth P Eapen, Susanne A Pulimood, Chandran Gnanamuthu, Mary Jacob, K R John
{"title":"A comparison of economic aspects of hospitalization versus ambulatory care in the management of neuritis occurring in lepra reaction.","authors":"Ravi H N,&nbsp;Renu George,&nbsp;Elizabeth P Eapen,&nbsp;Susanne A Pulimood,&nbsp;Chandran Gnanamuthu,&nbsp;Mary Jacob,&nbsp;K R John","doi":"10.1489/1544-581X(2004)72<448:ACOEAO>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<448:ACOEAO>2.0.CO;2","url":null,"abstract":"<p><p>Neuritis is one of the important causes of deformities and disabilities in leprosy. Neuritis has been managed both in the field and in hospital. This study was done to compare the economic aspects of cost of ambulatory vs in-patient management of neuritis in leprosy. The quality of life of the affected patients and the clinical improvement in the 2 groups were also studied. Twenty six patients fulfilling the study criteria were randomized into the ambulatory and in-patient group (13 in each group). The primary outcome examined was cost, in various categories; the secondary outcomes included pre- and post-treatment comparison of Quality of Life (QOL) scores and tests of sensory and motor function. The direct and indirect medical costs incurred by patients in the hospitalized group were higher than those patients in the ambulatory group. The difference in the direct medical costs between the two groups was Rs. 9110.5, and the extra direct non medical costs incurred by patients in the hospitalized group was Rs. 888.50 because of more frequent visits of family members. A greater percentage of ambulatory than in-patients returned to work in </= 15 days (53.8% vs 15.3%), and the mean duration before returning to work was 19.5 days ambulatory patients compared to 66.8 days for in-patients group. The QOL scores and motor and sensory function tests showed no significant difference between groups. Although the sample size was small, these preliminary results suggest that substantial cost minimization by ambulatory care is possible without significantly affecting the quality of life or peripheral nerve function.</p>","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"448-56"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24996144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Methotrexate in resistant ENL. 甲氨蝶呤治疗耐药ENL。
Bikash R Kar, Ravindra Babu
{"title":"Methotrexate in resistant ENL.","authors":"Bikash R Kar,&nbsp;Ravindra Babu","doi":"10.1489/1544-581X(2004)72<480:MIRE>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<480:MIRE>2.0.CO;2","url":null,"abstract":"<p><p>This is a report of a case of steroid resistant severe Type 2 reaction that was managed with methotrexate and prednisolone. Synergistic action of both the drugs in severe Type 2 reaction make them one of the preferred combinations in the absence of other agents such as thalidomide.</p>","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"480-2"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24995428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Deep vein thrombosis: a rare complication of thalidomide therapy in recurrent erythema nodosum leprosum. 深静脉血栓:沙利度胺治疗复发性麻风结节性红斑的罕见并发症。
Nand L Sharma, Vikas Sharma, Vinay Shanker, Vikram K Mahajan, Sandip Sarin
{"title":"Deep vein thrombosis: a rare complication of thalidomide therapy in recurrent erythema nodosum leprosum.","authors":"Nand L Sharma,&nbsp;Vikas Sharma,&nbsp;Vinay Shanker,&nbsp;Vikram K Mahajan,&nbsp;Sandip Sarin","doi":"10.1489/1544-581X(2004)72<483:DVTARC>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<483:DVTARC>2.0.CO;2","url":null,"abstract":"<p><p>A case of deep-vein thrombosis is reported in a female patient with multibacillary leprosy who received pulses of dexamethasone and cyclophosphamide for recurrent ENL that had not responded to prednisone and thalidomide.</p>","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"483-5"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24995430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Epidemiology of leprosy. 麻风病流行病学。
R Ganapati
{"title":"Epidemiology of leprosy.","authors":"R Ganapati","doi":"10.1489/1544-581X(2004)72<491b:EOL>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/1544-581X(2004)72<491b:EOL>2.0.CO;2","url":null,"abstract":"","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":"72 4","pages":"491; author reply 492"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24995433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
In situ hybridization in the histological diagnosis of early and clinically suspect leprosy. 原位杂交在早期和临床疑似麻风的组织学诊断中的应用。
Mohan Natrajan, Kiran Katoch, Vishwa M Katoch, Vishnu D Sharma, Dharmendra Singh, Devendra S Chauhan, Haribhan Singh
{"title":"In situ hybridization in the histological diagnosis of early and clinically suspect leprosy.","authors":"Mohan Natrajan,&nbsp;Kiran Katoch,&nbsp;Vishwa M Katoch,&nbsp;Vishnu D Sharma,&nbsp;Dharmendra Singh,&nbsp;Devendra S Chauhan,&nbsp;Haribhan Singh","doi":"10.1489/0020-7349(2004)72<296:ISHITH>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/0020-7349(2004)72<296:ISHITH>2.0.CO;2","url":null,"abstract":"<p><p>The present study tests the utility of the in situ hybridization procedure for M. leprae rRNA in the histological diagnosis of early leprosy and clinically suspect leprosy, both diagnostically demanding situations. The histological confirmation obtained with routine histopathology (Haematoxylin-Eosin staining for studying morphologic alterations and Fite-Faraco staining for demonstration of acid-fast bacilli) were 32% for early leprosy and 25% for clinically suspect leprosy. With performance of the in situ hybridization on the histologically unconfirmed cases, the positivity rates obtained were 58.8% and 55%, respectively. The results of the study confirm the utility of the procedure in the diagnostically difficult situations of early and suspect leprosy, and it is proposed that the procedure be employed in situations of clinical doubt.</p>","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":" ","pages":"296-305"},"PeriodicalIF":0.0,"publicationDate":"2004-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40919652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Commentary: is it really M. leprae? 评论:这真的是麻风分枝杆菌吗?
Paul E M Fine
{"title":"Commentary: is it really M. leprae?","authors":"Paul E M Fine","doi":"10.1489/0020-7349(2004)72<317:IIRML>2.0.CO;2","DOIUrl":"https://doi.org/10.1489/0020-7349(2004)72<317:IIRML>2.0.CO;2","url":null,"abstract":"","PeriodicalId":14078,"journal":{"name":"International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association","volume":" ","pages":"317-9"},"PeriodicalIF":0.0,"publicationDate":"2004-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40919654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书