Sanghun Nam, Sojung Park, Suyeong Bae, Ickpyo Hong
{"title":"Prevalence of Chronic Diseases by Cognitive Function Level and Age Group Among Middle-Aged and Older Korean Adults","authors":"Sanghun Nam, Sojung Park, Suyeong Bae, Ickpyo Hong","doi":"10.1002/gps.70159","DOIUrl":"https://doi.org/10.1002/gps.70159","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to investigate the age-dependent association between new cognitive classification and chronic diseases among middle-aged and older adults using Poisson regression analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We included 6940 people from the 2018 Korean Longitudinal Study of Aging. Cognitive status was classified as normal, moderate, and severe based on the participants' Korean Mini-Mental State Examination scores and instrumental activities of daily living. Poisson regression analysis was performed to predict the number of chronic diseases in middle-aged and older adults with grade three cognitive status. The number of predicted events at each cognitive level was calculated according to age.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the normal cognitive group, most of the participants were females 2515 (54.03), and the average age was 66.50 (SD = 8.62). Compared to the normal cognitive group (<i>n</i> = 4665), the incidence of chronic disease in the moderate cognitive impairment group (<i>n</i> = 1316) was 0.07 times that of the normal group, whereas, in the severe cognitive impairment group (<i>n</i> = 420), it was 0.21 times that of the normal group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Higher levels of cognitive impairment and older age were associated with a higher probability of having multiple chronic conditions. The study findings highlight the importance of integrative care with cognitive function and age in managing multiple chronic conditions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tiago Wiesner, Paula Grammatikos, Veerle van Gils, Sarah Bauermeister
{"title":"Relationship Between Clusters of Multimorbidity and Dementia Risk: A Systematic Review","authors":"Tiago Wiesner, Paula Grammatikos, Veerle van Gils, Sarah Bauermeister","doi":"10.1002/gps.70158","DOIUrl":"10.1002/gps.70158","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Emerging evidence demonstrates that multimorbidity, defined as the co-occurrence of at least two chronic conditions, may elevate the risk of dementia especially when certain conditions co-occur. Therefore, we investigated the available evidence on the relationship between clusters of multimorbidity and dementia risk in adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Embase, PsycINFO, and Ovid MEDLINE were searched until the ninth of February 2025. Included studies reported dementia risk or incidence in adult populations in relation to different clusters of multimorbidity. A narrative synthesis was structured according to the identified clusters across studies, their associations with dementia risk, and any moderation or stratification analyses for APOE ε4 allele carriership and C-reactive protein (CRP), among others. The Quality In Prognosis Studies (QUIPS) tool was used for quality assessment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 870 abstracts screened, 7 were included in the final synthesis. Significant relationships between clusters of multimorbidity and an elevated risk of dementia were identified in all studies. The most consistent findings related to cardiometabolic and mental health/neuropsychiatric clusters evidencing the highest dementia risk. Other multimorbidity clusters were less well studied and results regarding dementia risk varied across studies. Moderation and stratification analyses for APOE ε4 and CRP, where available, yielded inconsistent findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This systematic review highlights the importance of understanding multimorbidity clusters for early identification of dementia risk and targeted treatment approaches. Further research is required to explore relationships between multimorbidity clusters and dementia risk across different ethnic groups as well as the potential moderating role of lifestyle factors.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine Quinn, Helen Young, Vasileios Stamou, Kate Gridley, Clare Mason, Jan Oyebode
{"title":"Professionals' Views on Social Care Planning and Provision for People With Young-Onset Dementia and Their Families in England: Findings From the DYNAMIC Study","authors":"Catherine Quinn, Helen Young, Vasileios Stamou, Kate Gridley, Clare Mason, Jan Oyebode","doi":"10.1002/gps.70155","DOIUrl":"10.1002/gps.70155","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Access to appropriate social care post-diagnosis is crucial for people with young onset dementia (YOD) and their families. Yet care is hugely variable, frequently lacking, and poorly coordinated. We aimed to establish levels of awareness, knowledge, and practice among professionals regarding social care provision for people with YOD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A short survey (24 items) was developed based on previous research and through consultation with experts by experience and the project steering group. The aim was to establish awareness, knowledge, and practice among professionals regarding social care needs, care planning, and provision for people YOD. The survey was available online.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There were 139 responses from health and social care professionals. A wide range of situations triggered referrals to social care, illustrating the holistic impact of YOD. However, most referrals were triggered by crises rather than a proactive approach and were in response to carers' needs rather than those of the person with YOD. Referrals for advice and guidance around financial impacts were common. Most respondents reported there was no agreed care pathway and no YOD-specific guidelines in their service. Areas of good practice in social care provision included: person-centred and reablement based approaches; multi-disciplinary and multi-agency working; support from peers and the third sector; seamless care pathways and dedicated YOD services; support for carers; and personal budgets.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Staff need accurate knowledge and awareness of specific YOD-related issues to provide effective social care for those with YOD and their families. The current system tends to be reactive at point of crisis, whereas proactive planning and provision could pre-empt crises and provide more effective support. YOD-specific care pathways and guidance are needed to improve social care for this population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70155","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Climate-Induced Heat and the Mental Health of Older Adults: An Overlooked Challenge","authors":"John Jamir Benzon R. Aruta","doi":"10.1002/gps.70157","DOIUrl":"https://doi.org/10.1002/gps.70157","url":null,"abstract":"","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145038376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine M. Alexander, Hannah Earle, Anthony Martyr, Linda Clare
{"title":"Rapid Review of Interventions Designed to Enhance Personalised Care for People With Dementia When There Are Concerns About Reduced Awareness of Difficulties","authors":"Catherine M. Alexander, Hannah Earle, Anthony Martyr, Linda Clare","doi":"10.1002/gps.70153","DOIUrl":"https://doi.org/10.1002/gps.70153","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Awareness of difficulties varies in people with dementia. Low awareness, also termed anosognosia, has been implicated in carer stress and safety concerns, and can be a barrier to effective clinical communication. Little is known about how to manage situations arising from low awareness. This review looked for evidence of existing interventions to enhance care in situations regarding low awareness, and considered their utility, feasibility and acceptability when delivering personalised care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We used systematic review methodology, adapted for a rapid timeline, searching five databases and grey literature sources. The review built on an earlier scoping review about measuring awareness in dementia. The protocol was registered on PROSPERO (CRD42024626367). Interventions were included if targeted at people with any dementia type in any setting, or dyads or informal carers, or clinicians. Interventions of any type were eligible where awareness had been measured and addressed, and quantitative outcome data were available. Risk of bias of included articles was assessed. The review is reported as a narrative synthesis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From the database search, 6042 articles were screened, with additional findings from grey literature. Seven articles were included, describing heterogenous interventions. Two interventions aimed to enhance awareness as the primary goal. No intervention was aimed at informal carers or clinicians, and none addressed specific everyday concerns arising from low awareness. Five non-pharmacological interventions used methods involving music, a garden, a cognitive programme, interview-based psychosocial approaches or staff training. These appeared generally acceptable to care recipients, with some feasibility of use, but with limited efficacy. Intervention goals regarding awareness were poorly defined. Outcomes on awareness were mixed in comparison with control groups, with slowing of decline at best. Some improvement in mood, quality of life and coping was observed. Two drug interventions showed a reduction in neuropsychiatric symptoms but limited utility regarding awareness. Available public guidance about awareness issues is relevant but lacks a clear evidence-base.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The review identified evidence gaps for suitable interventions for managing low awareness in dementia. Existing interventions have limited efficacy and application regarding awareness. There is scope for fu","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of Professionals' Perceptions of Suicide in Older Adults Living in Care Homes","authors":"Rita Redondo, Carolina Pinazo-Clapés, Irene Checa, Sacramento Pinazo-Hernandis, Alicia Sales","doi":"10.1002/gps.70152","DOIUrl":"https://doi.org/10.1002/gps.70152","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Suicide among older adults living in care homes is a major public health challenge. This study analyses the perceptions and attitudes of professionals working in care homes towards suicidal ideation and suicide attempts in this population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A total of 338 nursing home professionals from Spain participated in the study. A vignette-based methodology was used, in which cases of suicidal ideation or suicide attempts were described, varying the gender of the actor. Responses to a questionnaire assessed perceived frequency, attention-seeking behaviour, ageism, experienced anxiety, perceived risk and likelihood of future suicide.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Professionals perceived suicidal ideation to be more common and normative in older adults, particularly women. However, they attributed a higher risk and likelihood of suicide to cases involving suicide attempts, which also elicited more anxiety. No significant differences were found in the perception of these situations as ‘attention-seeking behaviour'.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Acceptance of suicidal ideation as normal behaviour of suicidal ideation in older adults may reduce the perceived urgency to intervene, highlighting the need for specialised training to help identify risk signals and act promptly. This study highlights the importance of addressing age and gender bias in suicide prevention in care homes and advocates the development of evidence-based strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70152","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144998947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pareidolic Illusions and Associated Lower Regional Gray Matter Volumes in Community-Dwelling Older Adults Without Dementia: The Arakawa 65+ Study","authors":"Hana Nishida, Shogyoku Bun, Ryo Shikimoto, Hisashi Kida, Kouta Suzuki, Akihiro Takamiya, Jinichi Hirano, Hidehito Niimura, Hiroyuki Uchida, Masaru Mimura","doi":"10.1002/gps.70151","DOIUrl":"https://doi.org/10.1002/gps.70151","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Pareidolic illusions involve perceiving meaningful objects in ambiguous or visually complex stimuli. Although seen in dementia, their presence and associated neuroanatomical basis in older adults without dementia remain unclear. Investigating these illusions in this population may reveal early neurodegenerative changes preceding overt dementia. Such insights could support the use of pareidolic illusions as potential early markers for diagnosis and intervention. This study therefore aimed to examine the prevalence and associated neuroanatomical characteristics of pareidolic illusions in community-dwelling older adults without dementia, as assessed by the Noise Pareidolia Test (NPT).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We investigated the prevalence of pareidolic illusions in older adults aged 65–84 residing in Tokyo, Japan with suspected cognitive decline but without dementia. Participants were classified as cognitively normal or having mild cognitive impairment (MCI) based on standard criteria. Participants underwent NPT, and those who exhibited one or more pareidolic illusions were classified as pareidolia-positive. Additionally, a whole-brain voxel-based morphometry (VBM) of structural magnetic resonance imaging data was performed to assess gray matter volume differences associated with pareidolic illusions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Pareidolic illusions were present in 35.1% (155/441) of participants. These individuals were significantly older, had shorter years of education, and more likely to be diagnosed with MCI. VBM revealed significantly lower gray matter volume in bilateral temporal clusters—areas associated with face-related visuoperceptual processing—among pareidolia-positive individuals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Pareidolic illusions were relatively common in community-dwelling older adults without dementia. These illusions may be an early marker of neurodegenerative changes affecting visuoperceptual pathways, and may be detectable using NPT.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144934818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neural Basis of Anxiety in Dementia With Lewy Bodies","authors":"Naohiro Kimura, Yoshihiro Chadani, Ryo Kawai, Ryoko Fujito, Hideki Kanemoto, Ryuichi Takahashi, Tetsuo Kashibayashi, Shunichiro Shinagawa, Kenji Tagai, Kazunari Ishii, Manabu Ikeda, Hiroaki Kazui","doi":"10.1002/gps.70150","DOIUrl":"https://doi.org/10.1002/gps.70150","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The association between core clinical features and anxiety and the neural basis of anxiety in patients with dementia with Lewy bodies (DLB) are unknown. Therefore, this study examined the core clinical features associated with anxiety in DLB and identified the brain regions associated with anxiety using statistical imaging analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study was conducted using a part of the data from “The Japan multicenter study: Behavioral and psychological symptoms Integrated Research in Dementia-Retrospective Neuroimaging part”. Overall, 40 patients with probable DLB whose clinical dementia rating score was either 0.5 or 1 were included in this study. Anxiety was evaluated using the Neuropsychiatric Inventory (NPI). The incidence of each of the 4 core features was compared between patients with and without anxiety, and the brain regions associated with anxiety were examined using single-photon emission computed tomography data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patients with DLB with anxiety had a significantly higher percentage of fluctuating cognition than those without anxiety. The NPI anxiety score was significantly negatively correlated with regional cerebral blood flow in the right supramarginal gyrus in patients with DLB.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Anxiety in DLB is associated with fluctuating cognition. It is also likely that the brain regions associated with anxiety in DLB are potentially influenced by the neurofunctional characteristics of DLB, in which the parietal lobes are more likely to be impaired.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144934746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brendan Flanagan, Jayne Lynch, Sahil Kakar, Bernadette McGuinness, Katherine Patterson, A. Peter Passmore, Emma Louise Cunningham
{"title":"Most Patients Attending a Geriatrician-Led Memory Clinic are Not Eligible for Alzheimer's Disease-Modifying Drugs","authors":"Brendan Flanagan, Jayne Lynch, Sahil Kakar, Bernadette McGuinness, Katherine Patterson, A. Peter Passmore, Emma Louise Cunningham","doi":"10.1002/gps.70149","DOIUrl":"https://doi.org/10.1002/gps.70149","url":null,"abstract":"","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}