International Journal of Diabetes and Endocrinology最新文献_第2页

Diabetes Prevalence and Associated Factors in the Adult Population Aged 25–64 in the Humbo Districts of Woliata Zone Woliata地区Humbo地区25-64岁成人糖尿病患病率及相关因素

International Journal of Diabetes and Endocrinology Pub Date : 2023-04-20 DOI: 10.11648/j.ijde.20230801.15

S. Abebe, Wondimagegn Paulos, R. Tschopp

{"title":"Diabetes Prevalence and Associated Factors in the Adult Population Aged 25–64 in the Humbo Districts of Woliata Zone","authors":"S. Abebe, Wondimagegn Paulos, R. Tschopp","doi":"10.11648/j.ijde.20230801.15","DOIUrl":"https://doi.org/10.11648/j.ijde.20230801.15","url":null,"abstract":": The burden of disease caused by NCDs is quickly growing in emerging nations, with substantial social, economic, and health repercussions. However, data on the prevalence of diabetes and related variables among adults aged 25–64 years in Ethiopia, particularly in drought-stricken areas, is limited. The goal of this study is to find out how common diabetes is and what variables contribute to it in the middle-aged population. From January to February 2020, a community-based cross-sectional survey was undertaken among adults aged 25–64 years in Humbo district, southern Ethiopia. 587 people were chosen using a multi-stage sampling process. Weight, height, and fasting blood glucose levels were all measured. To enter data into a computer, Epi Data version 3.1 was utilized, which was subsequently exported to SPSS version 20 for analysis. Descriptive statistics and bivariate and multivariate logistic regression analyses were performed, and statistical significance was determined at a p-value of less than 0.05. Diabetes was found in 5.9% of the research participants (95 percent CI: 3.8–7.8). Age 45–54 (AOR = 4.80, 1.25, 18.32), physical inactivity (AOR = 5.33, 1.37, 20.72), family history of diabetes mellitus (AOR = 6.34, 95 percent CI: 2.43, 16.55), and obesity (AOR = 3.26, 95 percent CI: 1.43, 7.42) were all significantly associated with diabetes, according to multivariable logistic regression. The findings demonstrated the need for implementing educational public policies to encourage population behavior changes in order to prevent and control diabetes.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73571342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association between Insulin Signaling, Type2 Diabetes, And Cognitive Dysfunction 胰岛素信号、2型糖尿病和认知功能障碍之间的关系

International Journal of Diabetes and Endocrinology Pub Date : 2023-03-31 DOI: 10.36266/ijed/148

引用次数: 0

Impact of Balya Protex Powder on Fatigue Levels in Patients with Diabetes Mellitus Adhering to the Ayurveda-Based Comprehensive Diabetic Care Program 巴利亚蛋白粉对坚持以阿育吠陀为基础的糖尿病综合护理计划的糖尿病患者疲劳水平的影响

International Journal of Diabetes and Endocrinology Pub Date : 2023-03-24 DOI: 10.11648/j.ijde.20230801.14

R. Sane, R. Mandole, G. Amin, P. Ghadigaonkar, Harshita Gupta

{"title":"Impact of Balya Protex Powder on Fatigue Levels in Patients with Diabetes Mellitus Adhering to the Ayurveda-Based Comprehensive Diabetic Care Program","authors":"R. Sane, R. Mandole, G. Amin, P. Ghadigaonkar, Harshita Gupta","doi":"10.11648/j.ijde.20230801.14","DOIUrl":"https://doi.org/10.11648/j.ijde.20230801.14","url":null,"abstract":": Chronic fatigue in diabetic patients can be the outcome of protein deficiency. Plant based protein is closer to nature and bodily acceptable, hence we chose to assess plant-based protein “Balya Protex Powder” over whey protein. A prospective, multicentre, post-market study was conducted in India. Patients with a diagnosis of diabetes mellitus aged 18 years and above were included in this study. All patients adhered to the Comprehensive Diabetic Care (CDC) Program. Comparative data of change in fatigue score was collected retrospectively from type 2 diabetes mellitus patients assigned a low carbohydrate low calorie diet for 90 days. A total of 101 patients were included in this study, 50 patients consumed the Balya Protex Powder whilst 51 did not consume the Balya Protex powder whilst adhering to the CDC program. Weight of the patients decreased by 7.92% and 5.52% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. Body mass index decreased by 5.93% and 5.18% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. Abdomen girth decreased by 8.39% and 4.67% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. Weakness grade decreased by 83.69% and 47.61% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. All patients showed significant reduction in glycated hemoglobin (HbA1c) levels, however patients in the subgroup who were taking 30 gm of Balya Protex Powder daily showed 50% greater reduction in chronic fatigue score. It can be concluded that Balya Protex Powder consumption leads to good glycemic control with reduced fatigue in diabetic patients whilst adhering to the CDC program.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83441096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of imeglimin (Twymeeg) on pre-prandial glucose in patient with persisting post-prandial hyperglycemia 伊美美明对持续餐后高血糖患者餐前血糖的影响

International Journal of Diabetes and Endocrinology Pub Date : 2023-03-11 DOI: 10.36266/ijed/147

引用次数: 0

Impact of Myo B Basti on Type 2 Diabetes Mellitus Patients with Low Body Mass Index Myo B basi对低体重指数2型糖尿病患者的影响

International Journal of Diabetes and Endocrinology Pub Date : 2023-03-03 DOI: 10.11648/j.ijde.20230801.13

R. Sane, R. Mandole, G. Amin, Harshita Gupta

引用次数: 0

Biothesiometric Assessment of Persons Living with Diabetes Mellitus in a Tertiary Hospital in Uyo, Southern Nigeria 尼日利亚南部尤约一家三级医院糖尿病患者的生物计量学评估

International Journal of Diabetes and Endocrinology Pub Date : 2023-02-16 DOI: 10.11648/j.ijde.20230801.12

Onung Samuel, Akhimienho Kingsley, Amadi Collins, A. Ekanem, Umoren Ubong, Ekuma Ikwo, Asukpong Eso

{"title":"Biothesiometric Assessment of Persons Living with Diabetes Mellitus in a Tertiary Hospital in Uyo, Southern Nigeria","authors":"Onung Samuel, Akhimienho Kingsley, Amadi Collins, A. Ekanem, Umoren Ubong, Ekuma Ikwo, Asukpong Eso","doi":"10.11648/j.ijde.20230801.12","DOIUrl":"https://doi.org/10.11648/j.ijde.20230801.12","url":null,"abstract":": Background : The burden of foot ulceration and amputation among persons living with diabetes mellitus is quite huge and peripheral neuropathy is a well known risk factor for this. The prevalence of peripheral neuropathy and associated factors among persons living with diabetes, using an objective assessment (biothesiometer), is unknown in our study environment. Method : This was a cross-sectional study involving 108 age matched diabetes mellitus patients and controls. The study was conducted in the Diabetes Clinic of the University of Uyo Teaching Hospital, in Southern Nigeria. Basic demographics and other parameters such as duration of diabetes and glycated haemoglobin were recorded. All participants were recruited consecutively and screened for vibration perception threshold (VPT) using a biothesiometer. Participants with VPT ≥ 25 were considered to have significant neuropathy. Results : Significant neuropathy was recorded in 18 (33.3%) of the 54 diabetes patients. Only 3 (5.5%) of the 54 controls had significant neuropathy (p<0.01). The diabetes patients with significant neuropathy had a mean HbA1c of 8.9% compared to 7.3% for diabetes patients without significant neuropathy (p=0.02). The mean age of the diabetes patients with peripheral neuropathy was 54.0±2.3 years compared to 48.3±1.9 years for the diabetes patients without peripheral neuropathy (p<0.01). The mean duration of diabetes among diabetes patients with significant neuropathy was 10.3 years compared to 6.7 years for diabetes patients without significant neuropathy (p=0.01). Conclusion: There is a high prevalence of significant peripheral neuropathy among diabetes patients as determined using a biothesiometer. Early detection and achieving a good glycaemic control may help in reducing this burden which exposes the patients to the risk of possible amputation, depression and even death.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81647686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early elderly male with type 2 diabetes (T2D) changed from metformin to imeglimin (Twymeeg) 早期老年男性2型糖尿病(T2D)患者从二甲双胍改为伊美乐明(Twymeeg)

International Journal of Diabetes and Endocrinology Pub Date : 2023-02-05 DOI: 10.36266/ijed/145

引用次数: 1

The Effect of Aspirin on HbA1c Assay Among Diabetic Hypertensive Patients Attending Abu Aqulah Centre in Wad Madani, Gezira State, Sudan 阿司匹林对在苏丹Gezira州Wad Madani Abu Aqulah中心就诊的糖尿病高血压患者HbA1c检测的影响

International Journal of Diabetes and Endocrinology Pub Date : 2023-01-09 DOI: 10.11648/j.ijde.20230801.11

Abdalwahab Ahmed Abdalla, Salman Taha Ahmed Elmukashfi, Ahmed Yasin Hassan, A. Dafalla, Khalid Abdelsamea

引用次数: 0

GSTM1 and T1 null variants effects on the predisposition to type 2 diabetes mellitus in Turabah population, Saudi Arabia GSTM1和T1零变异体对沙特阿拉伯Turabah人群2型糖尿病易感性的影响

International Journal of Diabetes and Endocrinology Pub Date : 2022-10-31 DOI: 10.5897/jde2017.0116

A. Mergani, A. Mansour, O. M. Saleh, R. N. Zahran, A. M. Mustafa, M. A. Mohammed, T. Askar

{"title":"GSTM1 and T1 null variants effects on the predisposition to type 2 diabetes mellitus in Turabah population, Saudi Arabia","authors":"A. Mergani, A. Mansour, O. M. Saleh, R. N. Zahran, A. M. Mustafa, M. A. Mohammed, T. Askar","doi":"10.5897/jde2017.0116","DOIUrl":"https://doi.org/10.5897/jde2017.0116","url":null,"abstract":"Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia and associated with an increased production of reactive oxygen species (ROS) affecting beta cells in pancreas. Glutathione S-transferases (GSTs) are a family of antioxidant enzymes that include several classes of GSTs. These enzymes have important roles in decreasing ROS species and act as a kind of antioxidant defense. In a case-control study, the role of GSTMI and TI polymorphisms in predisposition for T2DM using multiplex polymerase chain reaction in 103 T2DM patients and 170 healthy controls from Turabah Province, Saudi Arabia was investigated. GSTM1 null variant was associated with higher genetic risk predisposing to T2DM in the study population. Our study revealed that individuals who are GSTM1 null genotype are associated with 1.863 times risk for predisposition to T2DM (Odds ratio = 1.863; 95% CI = 1.265 - 2.742; P-value=0.00001). While GSTT1 polymorphism has no role in genetic predisposing to T2DM in the study population ( Odds ratio = 1.053; 95% CI = 0.921 - 1.203 ) and its contribution in susceptibility for T2DM was only detected with combined double deletions with GSTM1 null variant in the population ( P-value = 0.041, Odds Ratio = 1.104; 95% CI = 0.991 - 1.230 ) . These results indicated that individuals who have GSTM1 null variant or GSTM1 and GSTT1 double deletion are at higher risk for developing T2DM than those who are positive genotyped for GSTT1 gene.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90489614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Future individualization medicine in diabetes with different responsive subtypes 未来针对不同反应型糖尿病的个体化治疗

International Journal of Diabetes and Endocrinology Pub Date : 2022-06-30 DOI: 10.36266/ijed/139

引用次数: 0