International journal of cancer and clinical research最新文献_第4页

Atypical Presentation of Triple-Negative Breast Cancer 三阴性乳腺癌的不典型表现

International journal of cancer and clinical research Pub Date : 2021-01-01 DOI: 10.23937/2378-3419/1410156

Ramon Eduardo Garcia-Cahuich, Felipe Rodríguez-Solis, N. García-Carrillo, Alondra Yereldi Naranjo-Cruz, Lorena Berenice Hernández-Hoil, María Valeria Jiménez-Báez

引用次数: 0

Total Maxillectomy in Children: A Report Two Cases 儿童上颌全切除术2例报告

International journal of cancer and clinical research Pub Date : 2021-01-01 DOI: 10.23937/2378-3419/1410159

Agustina Lorea, E. Figueroa, J. Larrañaga, C. Ruggeri

引用次数: 0

Nasal Cavity and Paranasal Sinuses Metastasis 鼻腔及鼻窦转移

International journal of cancer and clinical research Pub Date : 2020-12-31 DOI: 10.23937/2378-3419/1410143

S RuggeriCarlos, Acosta Lautaro, P. Valentina, Serrano Candelaria

{"title":"Nasal Cavity and Paranasal Sinuses Metastasis","authors":"S RuggeriCarlos, Acosta Lautaro, P. Valentina, Serrano Candelaria","doi":"10.23937/2378-3419/1410143","DOIUrl":"https://doi.org/10.23937/2378-3419/1410143","url":null,"abstract":"Introduction: Metastasis in the nasal cavity and paranasal sinuses are rare. The most common tumor that produces them is clear cell renal carcinoma. The objective of the study is to determine the incidence of metastases in the nasal cavity and paranasal sinuses among malignant rhinosinusal tumors in our patient poblation and survival after rhinosinusal metastasis treatment. Methods: The medical records of all patients who had malignant rhinosinusal tumors diagnosed and treated in the hospital Italiano of Buenos Aires from 1989 to 2019 were retrospectively reviewed. Patients who had metastases of primary neoplasms located outside the head were selected. Results: 67 patients with malignant tumors located in the nasal cavity and paranasal sinuses were diagnosed and treated. Eight patients had metastases in the nasal cavity and paranasal sinuses. All the patients at the time the metastasis was diagnosed had a controlled primary neoplasm. The treatments indicated were: Endonasal surgery with endoscopes with complete resection of the metastasis (3/8), radiotherapy (4/8), and chemo/radiotherapy (1/8). Only two patients who died from systemic metastases had persistent tumor in the paranasal sinuses (25%). Survival at one and two years was 75% and 25% respectively. Conclusions: The incidence of metastasis in the nasal cavity and paranasal sinuses among malignant neoplasms of the rhinosinusal region was 11.94%. Survival was poor, but the performed treatments had a high rate of local control and improved the quality of life of the patients.","PeriodicalId":13873,"journal":{"name":"International journal of cancer and clinical research","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88022282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Regeneration Abilities of Vertebrates and Invertebrates and Relationship with Pharmacological Research: Hypothesis of Genetic Evolution Work and Microenvironment Inhibition Role 脊椎动物和无脊椎动物的再生能力及其与药理研究的关系:遗传进化工作的假设和微环境抑制作用

International journal of cancer and clinical research Pub Date : 2020-09-28 DOI: 10.23937/2378-3419/1410142

M. Luisetto, Almukthar Naseer, HamidHabibah Abdul, G. Ibrahim, A. Nili, R. Yesvi, Mashori Ghulam Rasool, Gadama Tuweh Prince, Latyshev Oleg Yurievich

{"title":"Regeneration Abilities of Vertebrates and Invertebrates and Relationship with Pharmacological Research: Hypothesis of Genetic Evolution Work and Microenvironment Inhibition Role","authors":"M. Luisetto, Almukthar Naseer, HamidHabibah Abdul, G. Ibrahim, A. Nili, R. Yesvi, Mashori Ghulam Rasool, Gadama Tuweh Prince, Latyshev Oleg Yurievich","doi":"10.23937/2378-3419/1410142","DOIUrl":"https://doi.org/10.23937/2378-3419/1410142","url":null,"abstract":"A better understanding of the forces controlling cell growth will be essential for considering wound healing as a fundamental evolutionary with possibility of scar formation and reparative regeneration and the developing effective therapies in regenerative medicine and also in cancer. Historically, the literature has linked to cancer and tissue regeneration—proposing regeneration as both the source of cancer and a method to inhibit tumorigenesis. Aim of this work is to verify similarity and difference between this process un a evolutionary approach. The same verify the evolution of some factors involved in cancer development . In all this process ,genetically conserved or not , there are determinate kind of program ( finalistic or afinalistic ) whit a start messages but also a stop when the scope is achieved ( regeneration).It is clear that regeneration abilities in adult form is reduced in some superior vertebrates like humans and the same it seem related to an introduction of adaptative immunity .This review discusses two powerful regeneration models, the vertebrate urodele amphibians and invertebrate, in light of cancer regulation.","PeriodicalId":13873,"journal":{"name":"International journal of cancer and clinical research","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79141392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Solitary Brain Metastasis in Low-Risk Prostate Cancer - A Case Report 低危前列腺癌单发脑转移一例报告

International journal of cancer and clinical research Pub Date : 2020-06-04 DOI: 10.23937/2378-3419/1410138

Nguyen Sonha, Shaharyar Sameer, Dudheker Neil, Ranpura Vishal

引用次数: 2

Spontaneous Regression of Hepatic Diffuse Large B-cell Lymphoma in HIV and HCV Positive Patient: A Novel Case Study HIV和HCV阳性患者肝弥漫性大b细胞淋巴瘤自发消退:一个新的病例研究

International journal of cancer and clinical research Pub Date : 2019-10-23 DOI: 10.23937/2378-3419/1410127

A. Albert, Badeti Saiaditya, Liu Chen, Dongfang Liu, Donghong Cai

{"title":"Spontaneous Regression of Hepatic Diffuse Large B-cell Lymphoma in HIV and HCV Positive Patient: A Novel Case Study","authors":"A. Albert, Badeti Saiaditya, Liu Chen, Dongfang Liu, Donghong Cai","doi":"10.23937/2378-3419/1410127","DOIUrl":"https://doi.org/10.23937/2378-3419/1410127","url":null,"abstract":"Objective/Background: Diffuse large B-cell lymphoma (DLBCL) rarely occurs in the liver. Spontaneous regression of this tumor is extremely rare. We are reporting the first case of hepatic DLBCL, and we are reviewing the English literature for cases of spontaneous regression of DLBCL and cancer in general. Methods: A 60-year-old gentleman with a history of HIV and HCV infections presented with an incidental liver mass. He was diagnosed with DLBCL germinal cell type with high grade features based on the results of pathological/cytogenetics studies. He started HCV and HIV medication but refused lymphoma chemotherapy. Results: Radiological follow up during a four-year period showed a spontaneous regression of his liver mass to a non-detectable size. Review of the English literature revealed 18 cases of DLBCL spontaneous regression, none of which were found in the liver. Here, two mechanisms are proposed to explain this phenomenon; the immunologic and the genetic. Conclusion: Chemoimmunotherapy is recommended for all DLBCL patients. However, this case of DLBCL spontaneous regression in an HIV and HCV positive patient offers a rare platform to understand the immune and genetic mechanisms for cancer and lymphoma in particular.","PeriodicalId":13873,"journal":{"name":"International journal of cancer and clinical research","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84191017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cancer Patterns in Odisha - An Important Mining State in India 印度重要的矿业邦奥里萨邦的癌症模式

International journal of cancer and clinical research Pub Date : 2019-10-14 DOI: 10.23937/2378-3419/1410126

C. Sharmila, H. LevinePaul, Senapati Surendra Nath, Samanta Dipti Rani, Panigrahi Pinaki

{"title":"Cancer Patterns in Odisha - An Important Mining State in India","authors":"C. Sharmila, H. LevinePaul, Senapati Surendra Nath, Samanta Dipti Rani, Panigrahi Pinaki","doi":"10.23937/2378-3419/1410126","DOIUrl":"https://doi.org/10.23937/2378-3419/1410126","url":null,"abstract":"Background: Odisha, a populous state and a major mining belt in India has high levels of environmental carcinogens. There is no population-based cancer registry in Odisha, thus giving no opportunity to develop systematic studies on important regional carcinogens. This paper highlights current patterns of cancer as seen at Acharya Harihar Regional Cancer Centre (AHRCC), and provides the first opportunity to determine the most important research questions that could drive cancer control programs in Odisha. Methods: The analysis included all patients diagnosed and admitted with cancer at AHRCC, Cuttack, Odisha between January, 1st and December, 31st, 2012. Patient data were extracted from inpatient records, investigation reports and from in-patient registers and admission registers maintained by the Medical Records Department. Relevant information on diagnosis, primary site and demographic data were retrieved. Results: There were a total of 4811 patients, with a mean age of 47.5 ± 15.5 years, 44% males. The most common cancers among males were oral (14%), gastric (13%) and lung (10%) cancers. For females, among the most common cancers were breast (26%), cervix (21%), ovary (11%) gastric (5%) and gall bladder (3.7%). Seven percent of our cancer patients were aged ≤ 20 years. Acute lymphoblastic leukemia, Non-Hodgkin’s lymphoma, Hodgkin’s lymphoma and brain tumors were most common in this age group. Conclusion: Findings from this study suggest that particular attention be given to high prevalence cancers as import ant areas of research for risk factors and cancer control in Odisha.","PeriodicalId":13873,"journal":{"name":"International journal of cancer and clinical research","volume":"CE-23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84563393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The Role of Human Papillomavirus in Cervical Cancer 人乳头瘤病毒在宫颈癌中的作用

International journal of cancer and clinical research Pub Date : 2019-09-28 DOI: 10.23937/2378-3419/1410125

Smolarz Beata, Samulak Dariusz, M. Marianna, Romanowicz Hanna, Kojs Zbigniew, W. Luiza, M. MichalskaMagdalena

引用次数: 5

TCM Combined Chemoradiotherapy in the Treatment of Limited-Stage Small Cell Lung Cancer: Current Status and Perspectives 中药联合放化疗治疗有限期小细胞肺癌的现状与展望

International journal of cancer and clinical research Pub Date : 2019-09-21 DOI: 10.23937/2378-3419/1410124

J. Staffan, Olsson Hans

引用次数: 0

The Resected Tumour Volume of the Specimen as a Marker of the Quality of the Transurethral Resection in T1 Urinary Bladder Cancer T1型膀胱癌经尿道切除肿瘤标本体积作为肿瘤切除质量的标志

International journal of cancer and clinical research Pub Date : 2019-09-18 DOI: 10.23937/2378-3419/1410123

J. Staffan, Olsson Hans

{"title":"The Resected Tumour Volume of the Specimen as a Marker of the Quality of the Transurethral Resection in T1 Urinary Bladder Cancer","authors":"J. Staffan, Olsson Hans","doi":"10.23937/2378-3419/1410123","DOIUrl":"https://doi.org/10.23937/2378-3419/1410123","url":null,"abstract":"Objective: To study the resected volume (RV) and the resected tumour volume (RTV) in the microscopic examination of the TUR specimen in relation to tumour size, clinical variables and outcome. Materials and methods: This prospectively performed population-based study included all patients in the Southeast Healthcare Region in Sweden with T1 UBC registered in the period 1992-2001, inclusive. RV, RTV and important clinic-pathological variables were studied. All patients had T1 tumours including detrusor muscle at the histopathological examination. Median values for RV and RTV were cut-off points for dichotomisation and 3 cm was the cut-off point for tumour size measured at TUR. Recurrence and progression were analysed using Kaplan-Meier curves with Log-rank test and Cox Proportional Hazards analysis. Results: Out of 211 patients we observed low RV in 112 (53%), low RTV in 113 (54%) and tumour size > 3 cm in 109 (52%). Patients with tumour size > 3 cm and low RV had shorter time to recurrence and progression compared to those with high RV (p = 0.006 and p = 0.087, respectively) and this was also the case when comparing patients with low RTV versus high RTV (p < 0.001 and p = 0.017, respectively). Conclusions: Patients with tumours > 3 cm and low RV or low RTV at TUR for T1 UBC are at higher risk for recurrence or progression, indicating an insufficient TUR. Extensive SLR is particularly important for these patients. RV and RTV might also be used as markers to monitor the quality of the TUR to improve treatment outcome.","PeriodicalId":13873,"journal":{"name":"International journal of cancer and clinical research","volume":"21 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91461943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0