International Journal of Contemporary Pediatrics最新文献_第4页

Study of usefulness of budesonide nebulization in oxygen dependent preterm newborns in NICU 研究布地奈德雾化疗法对新生儿重症监护室中依赖氧气的早产新生儿的作用

International Journal of Contemporary Pediatrics Pub Date : 2024-04-04 DOI: 10.18203/2349-3291.ijcp20240924

Rajith M. L., Punyashree R.

{"title":"Study of usefulness of budesonide nebulization in oxygen dependent preterm newborns in NICU","authors":"Rajith M. L., Punyashree R.","doi":"10.18203/2349-3291.ijcp20240924","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20240924","url":null,"abstract":"Background: Increased duration of neonatal intensive care unit (NICU) stay of preterm neonates have becoming an emotional and financial burden to parents leading to very high chances of parents discontinuing the treatment and thus increased morbidity and mortality of neonates. Oxygen dependency is the major cause of the prolonged NICU stay for the neonates having respiratory illness like respiratory distress syndrome (RDS), meconium aspiration syndrome (MAS), and pneumonia. Inhaled budesonide being a safe immunosuppressor has shown the promising result in the treatment of these immune system activated respiratory disorders of neonate and thus reduction of oxygen dependency and later reducing the hospital stay duration. The intent of this study is to evaluate the usefulness of inhaled budesonide in such respiratory disorders of neonate.\u0000Methods: A randomized controlled trial involving 60 oxygen dependent neonates in NICU was conducted from July 2021 to March 2023.\u0000Results: Budesonide nebulization decreased the duration of oxygen dependency of neonates and thus reduced NICU stay.\u0000Conclusions: Budesonide nebulization is associated with improvements in respiratory parameters in neonates with RDS, MAS, Pneumonia leading to early oxygen weaning and early discharge.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"111 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140742737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myositis as a de-novo extraintestinal manifestation of ulcerative colitis in a pediatric patient developing post-colectomy: a case report 肌炎是一名结肠切除术后儿童患者溃疡性结肠炎的肠外表现：病例报告

International Journal of Contemporary Pediatrics Pub Date : 2024-04-04 DOI: 10.18203/2349-3291.ijcp20240925

Kristīne Kalēja, Ilze Apine, Inita Kaže

引用次数: 0

A study of incidence of respiratory distress syndrome in newborns born to mothers with gestational diabetes 妊娠糖尿病母亲所生新生儿呼吸窘迫综合征发病率研究

International Journal of Contemporary Pediatrics Pub Date : 2024-04-04 DOI: 10.18203/2349-3291.ijcp20240923

Rajith M. L., Punyashree R.

{"title":"A study of incidence of respiratory distress syndrome in newborns born to mothers with gestational diabetes","authors":"Rajith M. L., Punyashree R.","doi":"10.18203/2349-3291.ijcp20240923","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20240923","url":null,"abstract":"Background: Hyaline membrane disease/RDS is an important cause for newborn morbidity and mortality. Many studies have established an association of infants of diabetic mothers (IDMs) with respiratory distress syndrome (RDS) since decades. Modern lifestyle changes have increased the prevalence of obesity in women and thus diabetes in pregnancy. Maintaining strict euglycemia is a double-edged sword in pregnancy which has been affecting the neonatal health and respiratory maturity in particular which has been associated with increased mortality and morbidity.\u0000Methods: It was a prospective case control study done over a span of one year.\u0000Results: Hyaline membrane disease (RDS) is significantly associated with gestational diabetes mellitus (GDM).\u0000Conclusions: Even our study emphasized the ill effects of gestational diabetes on the respiratory development of baby. Most of the babies are manageable and outcome can be drastically improved by early diagnosis and efficient treatment. Education and anticipation of the complications and prompt referral are the need of the hour in peripheries and advancement of neonatal intensive cares in the referral hospitals is needed.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"55 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140742052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethmocephaly: a rare but lethal congenital anomaly 乙脑：一种罕见但致命的先天性畸形

International Journal of Contemporary Pediatrics Pub Date : 2024-02-22 DOI: 10.18203/2349-3291.ijcp20240351

Aneeta Chaudhary, Arun Kumar Arya

引用次数: 0

Clinical profile of pediatric acute renal failure patients requiring renal replacement therapy age less than 15 years: an ambivalent COHORT study 需要肾脏替代疗法的 15 岁以下小儿急性肾衰竭患者的临床概况：一项矛盾的 COHORT 研究

International Journal of Contemporary Pediatrics Pub Date : 2024-02-22 DOI: 10.18203/2349-3291.ijcp20240346

Jayesh R. Solanki, Kishan S. Patel

{"title":"Clinical profile of pediatric acute renal failure patients requiring renal replacement therapy age less than 15 years: an ambivalent COHORT study","authors":"Jayesh R. Solanki, Kishan S. Patel","doi":"10.18203/2349-3291.ijcp20240346","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20240346","url":null,"abstract":"Background: Acute kidney injury (AKI) is characterized by a reversible increase in the blood concentration of creatinine and nitrogenous waste products and by the inability of the kidney to regulate fluid and electrolyte homeostasis appropriately. There is minimal data on the clinical profile of pediatric AKI patients age less than 15 years who required renal replacement therapy (RRT).\u0000Methods: A total of 301 patients (3%) were diagnosed with AKI, amongst them 66 patients who required RRT from January 2021 to December 2022 were enrolled. Their clinical, biochemical, and etiological profile were studied to find out their influence in modifying the outcome of AKI patients requiring RRT.\u0000Results: AKI was noted in 301 patients (3%), amongst them 66 patients we had analyzed who underwent RRT. Result were analyzed in three age group (0-2 month, 2 month-8 year, 8 year-15 year). Male preponderance was seen amongst all age groups with male: female ratio being 2:1, 5:1 and 1.8:1 respectively and rural area preponderance seen in all age groups. Birth asphyxia, neonatal sepsis and septicemia were leading etiologies in different groups. Peritoneal dialysis (PD) was only RRT modality in the 0-2 month age group, while hemodialysis and PD modalities were used in rest groups. Multi-organ dysfunction syndrome was commonly seen comorbidity associated with all groups along with pyogenic meningitis, and encephalopathy. Mortality rate was observed at 47% (n=31).\u0000Conclusions: From our study, we conclude that to expand the facility of point of care, hemodialysis facility in ICUs with a larger study or multicentric study in the pediatric age group is required.\u0000 ","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"2 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139957920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Typical presentation of mucopolysaccharidosis type IVA: a case report 黏多醣症IVA型的典型表现：一份病例报告

International Journal of Contemporary Pediatrics Pub Date : 2024-02-16 DOI: 10.18203/2349-3291.ijcp20240328

Kovvuru Ashrita, Ethuri Lokesh

引用次数: 0

Current clinical profiles of acute respiratory tract infections in children between 2 months to 5 years 目前 2 个月至 5 岁儿童急性呼吸道感染的临床概况

International Journal of Contemporary Pediatrics Pub Date : 2024-01-25 DOI: 10.18203/2349-3291.ijcp20240089

Junita Desouza, Mohan Patil, Indu Thomas, Juanita Desouza

{"title":"Current clinical profiles of acute respiratory tract infections in children between 2 months to 5 years","authors":"Junita Desouza, Mohan Patil, Indu Thomas, Juanita Desouza","doi":"10.18203/2349-3291.ijcp20240089","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20240089","url":null,"abstract":"Background: The nascent respiratory tract of infants is highly vulnerable to frequent infections, thereby making acute respiratory infections a major risk factor for under five years morbidity and mortality. The clinical presentation of acute respiratory tract infections (ARTI) is however ambiguous and varied depending on a plethora of factors. The aim was to delineate the respiratory disease profiles of children aged 2 months-5 years in Western Maharashtra.\u0000Methods: The present cross sectional analytical study was conducted on 249 children aged between 2 months-5 years consulting the Pediatric wards and OPD with complaints of fever with cough, cold, breathlessness, and chest pain. A comprehensive medical history was procured, followed by general and systemic examinations. Infections were assessed and x-ray was taken for all the patients. Data was analyzed using statistical software R version 4.0.3 and Microsoft Excel.\u0000Results: The male:female ratio in the study was 137:112. Cold (80.72%) and cough (74.3%) were the most widely experienced symptoms among patients, while chest pain (0.8%) was the least common. Among 249 cases, upper respiratory tract infection (URTI; 60%) was more predominantly noted than lower respiratory tract infections (LRTI; 44.8%). Nasopharyngitis (34.14%) and tonsillopharyngitis (6.83%) were the commonly prevalent types of URTI whereas pneumonia and bronchiolitis were the most recurrent types in the LRTI.\u0000Conclusions: Practitioners must consider the possibility of acute URTI more closely and must not be quick to disregard common symptoms such as cold and cough. Misdiagnosis or delayed diagnosis can severely hamper the prognosis of ARTI in young children. Hence, keeping abreast of the current clinical profiles exhibited by ARTI is of paramount importance for practitioners and the general population in the fight against under 5 mortalities.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"19 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139595565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of clinical profile and outcome of children presented with poisoning in tertiary care hospital 三级医院中毒儿童的临床概况和治疗结果研究

International Journal of Contemporary Pediatrics Pub Date : 2024-01-25 DOI: 10.18203/2349-3291.ijcp20240094

Chirag D. Shah, Aditi Kaple, Kankana Pratihar, Kush Patel, Jhalak Patel

{"title":"Study of clinical profile and outcome of children presented with poisoning in tertiary care hospital","authors":"Chirag D. Shah, Aditi Kaple, Kankana Pratihar, Kush Patel, Jhalak Patel","doi":"10.18203/2349-3291.ijcp20240094","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20240094","url":null,"abstract":"Background: Poisoning is a common paediatric emergency. Worldwide estimate suggests that the rate of poisoning in under 20 years is 1.8 per one lakh population and for India it ranges between 0.6 to 11.6%.\u0000Methods: The study was conducted at B. J. Medical College Ahmedabad and Civil Hospital, Ahmedabad. A prospective analytical study consisting of total 110 patients, admitted in the intensive care unit during the period from June 2018 to November 2018 with inclusion criterion of children <12 years of age, presented with history of consumption of poisonous substances/insect bite irrespective of signs and symptoms excluding cases of food poisoning and idiosyncratic drug reactions. Detailed proforma was filled after taking necessary consent from the parents. Routine investigations and gastric samples for forensic analysis were sent in all irrespective of type or route of poisoning. Specific investigations done wherever required. Analysis of outcomes done using chi square.\u0000Results: The most common age group was 3-6 years with male to female ratio of 1.5:1. 99.1% poisoning were accidental with hydrocarbon poisoning being the most common of all (27.2%), followed by household substance poisoning in 20.9%. Snakebite was the most common insect bite (10.9%). The average duration of stay was 3.9 days, 8.1% children died with maximum mortality happened in children presented after 6 hours of intoxication.\u0000Conclusions: Management of poisoning requires immediate advice and first aid, followed by a directed treatment. Decontamination, enhanced elimination, antidotes, and supportive care are commonly used to manage poisoning cases.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"73 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139596890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hot cross bun in pediatric age multi-system atrophy an unusual presentation 小儿多系统萎缩症中的热十字包是一种不寻常的表现

International Journal of Contemporary Pediatrics Pub Date : 2024-01-25 DOI: 10.18203/2349-3291.ijcp20240105

Lokesh Naik Mude, O. Shukla, Rinki H. Shah, Rajesh Rambhai Barad

{"title":"Hot cross bun in pediatric age multi-system atrophy an unusual presentation","authors":"Lokesh Naik Mude, O. Shukla, Rinki H. Shah, Rajesh Rambhai Barad","doi":"10.18203/2349-3291.ijcp20240105","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20240105","url":null,"abstract":"A 10-year-old female was brought to emergency department with complaint fever, cold, and cough for 5 days followed by weakness of upper limb weakness more than Lower limb associated with inability to walk/stand, brought to emergency with altered sensorium. Nervous system: Confused and altered, tone is normal, power: 3/3 in upper limbs 2/2 in lower limbs and reflexes in bilateral knee brisk, bilateral plantar-extensor; On general examination revealed hypomimia, dysarthria and bilateral bradykinesia along with ataxic gait and pyramidal signs. Blood investigation were normal and diagnosis made by neuroimaging s/o: Bilaterally symmetrical abnormal signal in both postero-medial thalami, bilateral insular cortices, pons and bilateral middle cerebellar peduncles. It is extending into pons involving transverse pontocerebellar tracts and median pontine raphe nuclei giving 'Hot cross bun sign' (HCBS). During course of treatment child had autonomic disturbances. Child was treated with supportive medication and methyl-presdnisolone followed by oral steroid. Child had responded to treatment given and child has been discharged with no neurological deficit on oral medications. We concluded autonomic dysfunction in any patient presenting with acute onset of weakness with short duration must evaluate for MSA and institute appropriate treatment.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"40 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139598025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myocardial dysfunction and thrombocytopenia, rare manifestations of acute post-streptococcal glomerulonephritis: case report 心肌功能障碍和血小板减少是链球菌感染后急性肾小球肾炎的罕见表现：病例报告

International Journal of Contemporary Pediatrics Pub Date : 2024-01-25 DOI: 10.18203/2349-3291.ijcp20240103

Nazish Malik, Mohammad Arif

{"title":"Myocardial dysfunction and thrombocytopenia, rare manifestations of acute post-streptococcal glomerulonephritis: case report","authors":"Nazish Malik, Mohammad Arif","doi":"10.18203/2349-3291.ijcp20240103","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20240103","url":null,"abstract":"In this case report, we present two rare cases of acute post-streptococcal glomerulonephritis with unusual manifestations in the form of myocardial dysfunction and thrombocytopenia. APSGN typically follows Streptococcal infections and is characterized by inflammation of glomeruli. These cases, however, exhibited additional complexities. The first case involved a 12-year-old male with fever, shortness of breath, and cough. He presented with pedal edema, pallor, and hypertension. Laboratory findings revealed thrombocytopenia, anemia, and decreased C3 levels, while echocardiography indicated grade-3 diastolic dysfunction. The second case featured a 5-year-old female with icterus, fever, and body swelling. She had a palpable liver, pleural effusion, and thrombocytopenia. Both cases were diagnosed with APSGN, congestive heart failure, and thrombocytopenia. Thrombocytopenia is a rare finding in APSGN, and its etiology remains debated. Treatment included decongestive therapy and antihypertensive medication. Notably, thrombocytopenia in both cases improved without specific intervention, challenging the necessity of steroids or IVIg therapy. This report illuminates on the atypical presentation of APSGN, highlighting the potential coexistence of glomerulonephritis and thrombocytopenia. It underscores the need for further research to better understand this association and determine appropriate treatment protocols. These cases emphasize the importance of considering diverse clinical manifestations in the context of APSGN, calling for a broader understanding of this condition.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"54 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139599045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0