International Journal of Clinical Rheumatology最新文献_第9页

Predictive value of rheumatoid factor titre in cryoglobulinemia in Hepatitis C positive patients 类风湿因子滴度在丙型肝炎阳性患者冷球蛋白血症中的预测价值

International Journal of Clinical Rheumatology Pub Date : 2019-01-01 DOI: 10.4172/1758-4272.1000222

R. Ghaleb, H. Sadek, Abdo Mohammed

{"title":"Predictive value of rheumatoid factor titre in cryoglobulinemia in Hepatitis C positive patients","authors":"R. Ghaleb, H. Sadek, Abdo Mohammed","doi":"10.4172/1758-4272.1000222","DOIUrl":"https://doi.org/10.4172/1758-4272.1000222","url":null,"abstract":"Background/objective: HCV viremia has been known to provoke a plethora of autoimmune syndromes as well as nonspecific rheumatologic manifestations. HCV is the most frequent cause of mixed cryoglobulinemia, which is characterized by endothelial deposition of rheumatoid factor containing immune complexes and endorgan vasculitis. Rheumatoid factor positivity is found to be more prevalent among patients with HCV infection compared to the general population. The aim of the study was to ascertain the relationship of rheumatoid factor titer with cryoglobuliemia in hepatitis C virus positive patients and to assess its relation with different disease characteristics. Methods: A cross sectional study was carried out through one year. Fifty patients known to suffer from HCV were subjects of the study. Patients were interviewed and demographic, clinical and serologic data were recorded. All patients were tested for cryoglobulins by crude method and rheumatoid factor titer was determined in all patients. Child-Pugh classification was used for assessment of liver cell failure. Data were analyzed by the Statistical Package for the Social Sciences (SPSS, version 17). Data analysis is done by using Chi-Squared test (χ2) test and Fisher’s exact test as appropriate. Associations between interval, ordinal and dichotomous variables were tested by Pearson`s Product Moment Correlation Coefficients (r). Results: Cryoglobulinemia was detected in 36 (72%) patients out of the 50 HCV patients. Rheumatoid Factor (RF) was positive in 38% patients (76%). All HCV patients who were positive for cryoglobulin had a positive RF. Presence of RF found to be positively significantly correlated with the presence of cryogloulins in HCV patients. Conclusions: HCV infection is a major contributing factor of mixed cryoglobulinemia with elevation in RF titre. Positive anti-HCV antibodies together with highly positive RF titre in the presence of musculoskeletal, neurological and cutaneous manifestations strongly suggest the diagnosis of mixed cryoglobulinemia.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82832115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Genetic markers in HLA region to identify patients with tuberculosis risk, in RA subjects HLA区域的遗传标记可识别RA受试者中结核病风险的患者

International Journal of Clinical Rheumatology Pub Date : 2019-01-01 DOI: 10.4172/1758-4272.1000218

G. Lugo-Zamudio, R. Barbosa-Cobos, D. Delgado-Ochoa, Rodrigo Arreola

引用次数: 1

A validation study of the Taiwanese version of the assessment of spondyoarthritis international society health index 台湾版脊柱炎国际社会健康指数评估之验证性研究

International Journal of Clinical Rheumatology Pub Date : 2019-01-01 DOI: 10.37532/1758-4272.2019.14(5).225-233

Holman Chan

{"title":"A validation study of the Taiwanese version of the assessment of spondyoarthritis international society health index","authors":"Holman Chan","doi":"10.37532/1758-4272.2019.14(5).225-233","DOIUrl":"https://doi.org/10.37532/1758-4272.2019.14(5).225-233","url":null,"abstract":"Objective: The objective is to validate the Assessment of SpondyloArthritis International Society Health Index (ASAS HI) in patients with Spondyloarthritis (SpA). Methods: We recruited 102 consecutive patients with SpA from two rheumatology clinics. Demographic data was collected. Recruited patients completed the ASAS HI and other self-assessment questionnaires (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Global Index (BASGI), Oswestry Disability Index (ODI), Short Form (36) Health Survey (SF-36), Euro-quality-of-life-5D (EQ5D), Hospital Anxiety and Depression Scale (HADS) and Work Productivity and Activity Impairment questionnaire (WPAI)). Ankylosing Spondylitis Disease Activity Score (ASDAS) was calculated. Correlations between ASAS HI and the questionnaires were determined for concurrent validity. The ASAS HI score was also checked for test-retest reliability, internal consistency, discriminative ability, and floor and ceiling effects. Results: The ASAS HI achieved good test-retest reliability (ICC 0.87), internal consistency, and discriminative ability. It had no floor or ceiling effect. Favourable concurrent validity was found with measures of disease activities (BASDAI, ASDAS), quality-of-life (SF 36, EQ5D), psychological symptoms (HADS), and work disability (WAPI). The ASAS HI was able to differentiate higher disease activity and psychological symptoms. Patients found it easy to understand, comprehensive, relevant and appropriate to their disease. The average time needed to complete the questionnaire was 2 minutes 36 seconds ± 1 minute 2 seconds. Conclusion: The Taiwanese version of the ASAS HI is a validated tool in the assessment of health status in patients with SpA.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"46 1","pages":"225"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88768400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Refractory thrombocytopenia in SLE patient with massive thigh hematoma and hematuria successfully treated with Rituximab: Case Report 利妥昔单抗治疗难治性血小板减少合并大量大腿血肿和血尿的SLE患者:病例报告

International Journal of Clinical Rheumatology Pub Date : 2019-01-01 DOI: 10.4172/1758-4272.1000219

Maha J Aljasser, Hanady Manasfi, Amjad Abdelnabi Hanan Y Abdurabu

{"title":"Refractory thrombocytopenia in SLE patient with massive thigh hematoma and hematuria successfully treated with Rituximab: Case Report","authors":"Maha J Aljasser, Hanady Manasfi, Amjad Abdelnabi Hanan Y Abdurabu","doi":"10.4172/1758-4272.1000219","DOIUrl":"https://doi.org/10.4172/1758-4272.1000219","url":null,"abstract":"Background: Systemic Lupus Erythematosus is a multisystemic inflammatory disease with broad clinical presentation, 9.5% to 44.5% of patients with SLE have thrombocytopenia complication of different grades. No significant increase in risk of hemorrhage was found in patients with SLE with moderate thrombocytopenia, while those with severe thrombocytopenia frequently developed bleeding, which is associated with the activity of the disease and potentially life-threatening condition, if left untreated. Case presentation: We report a case of 35-year-old SLE male patient, presented with sudden painful large non-traumatic ecchymotic lesion on the right thigh extending to calf with macroscopic hematuria. At presentation, platelets count was 50 x 109/L with hemoglobin dropping from 10.3 to 6.9 g/dl. Anticardiolipin antibody and Antiphospholipid antibody were absent. Other factors including infection and visceral involvement were excluded. MRI of the thigh showed huge intramuscular hematoma extending to calf. Satisfactory control was partially achieved with platelet transfusion, pulse steroid, cellcept, IVIG (intravenous immunoglobulins) and consequently Rituximab. Our case describes refractory thrombocytopenia not responding to multiple agents including high dose steroids, cellcept, platelet transfusion, IVIG (intravenous immunoglobulins) and cyklokapron; however, it achieved its complete remission with Rituximab. Bleeding is not usual presentation with moderate thrombocytopenia in SLE patients and presumably played a role in prognosis. Conclusion: Our case report has demonstrated the efficacy of treating refractory thrombocytopenia resistant to steroids due to Systemic Lupus Erythematosus in whom other reasonable options have been exhausted.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80663970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synovial fluid level of vascular endothelial growth factor (VEGF) can predict functional status and radiological severity in patients with knee osteoarthritis (OA) 滑膜液血管内皮生长因子(VEGF)水平可预测膝关节骨性关节炎(OA)患者的功能状态和放射学严重程度。

International Journal of Clinical Rheumatology Pub Date : 2019-01-01 DOI: 10.4172/1758-4272.1000217

R. Abdel-Magied, Hanaa A.S. AbuOmar, A. Higazi, Abeer Awad Amal A Hassan

{"title":"Synovial fluid level of vascular endothelial growth factor (VEGF) can predict functional status and radiological severity in patients with knee osteoarthritis (OA)","authors":"R. Abdel-Magied, Hanaa A.S. AbuOmar, A. Higazi, Abeer Awad Amal A Hassan","doi":"10.4172/1758-4272.1000217","DOIUrl":"https://doi.org/10.4172/1758-4272.1000217","url":null,"abstract":"Aim of the work: Detection of serum and synovial fluid level of Vascular Endothelial Growth Factor (VEGF) in patients with knee osteoarthritis (OA) and to determine its relation to radiological severity and function status. Patients and methods: Thirty OA patients and thirty controls were included. Function status was assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Knee pain evaluated using the Visual Analogue Scale (VAS). Serum and synovial fluid level of VEGF were measured. Kellgren-Lawrence grading scale (KL) used to assess radiological severity. Results: The mean of patients’ age was 50.33 ± 5.3 years (20 females and 10 males) with disease duration of 7.03 ± 2.12 years. Mean synovial fluid VEGF of OA patients was 964.1 ± 396.72, mean serum VEGF of OA patients was 219.1 ± 96.95. No difference between serum VEGF of patients and control groups (p=0.787). Significant positive correlation between serum and synovial VEGF in OA patients (r=0.58, p=0.001). Significant positive correlation between the synovial fluid VEGF and patients’ age, disease duration, inactivity stiffness, ESR, VAS, WOMAC and KL grade scale (p‹0.0001,p=0.029,p‹0.0001,p‹0.0001,p=0.00 3,p‹0.0001,p‹0.0001). Significant positive correlation between serum VEGF and patients’ age, inactivity stiffness, WOMAC, ESR and KL grade scale (p‹0.0001, p=0.005, p=0.001, p=0.001,p=0.010). Synovial fluid VEGF was the significant predictors for determining the function status (p‹0.0001); while for determining severity; synovial fluid VEGF, patients’ age and VAS were significant predictors (p‹0.0001,p=0.001 and p=0.029 respectively). Conclusion: Serum and synovial fluid VEGF correlated with the clinical features, functional status and radiological features of Knee OA. Synovial VEGF can predict both functional impact and radiological severity in patients with knee OA.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80265792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Favorable outcome of allogenic hematopoietic stem cell transplantation in farber disease 异体造血干细胞移植治疗脂肪疾病的良好结果

International Journal of Clinical Rheumatology Pub Date : 2018-01-01 DOI: 10.4172/1758-4272.1000204

A. Hamidieh, T. Rostami, M. Behfar, A. Ghavamzadeh

引用次数: 1

An unusual presentation of inflammatory myopathy in a patient on natalizumab treatment for multiple sclerosis: A case report and review of myopathological classification of inflammatory myopathy 在接受纳他珠单抗治疗多发性硬化症的患者中，炎症性肌病的不寻常表现:炎症性肌病的病例报告和肌肉病理分类的回顾

International Journal of Clinical Rheumatology Pub Date : 2018-01-01 DOI: 10.4172/1758-4272.1000185

B. Zulfiqar, J. Chua, S. Hassan

{"title":"An unusual presentation of inflammatory myopathy in a patient on natalizumab treatment for multiple sclerosis: A case report and review of myopathological classification of inflammatory myopathy","authors":"B. Zulfiqar, J. Chua, S. Hassan","doi":"10.4172/1758-4272.1000185","DOIUrl":"https://doi.org/10.4172/1758-4272.1000185","url":null,"abstract":"Acquired immune and inflammatory myopathies (IIMs) are traditionally subdivided into dermatomyositis, polymyositis, inclusion body myositis (IBM) and necrotizing autoimmune myopathy (NAM). Our patient is a 38-year old female who had history of Multiple Sclerosis and was on Natalizumab. Almost a year later, she presented with acute proximal bilateral upper extremity weakness with elevated CPK. She was initially labeled as having ‘viral myositis’. Her subsequent two admissions demonstrated worsening of muscle weakness with dysphagia which was initially unresponsive to high dose of steroids. She had an EMG which showed irritative myopathy and a muscle biopsy which showed IMPP. She eventually responded to pulse dose of steroids and IVIG and Natalizumab was held. The temporal relationship between the development of inflammatory myopathy in our patient and subsequent improvement in her course after discontinuation of the drug suggests that natalizumab may have played a role in our patient’s disease and warrants further investigation and vigilance. In addition to the case report, we hope to elaborate on the myopathological descriptions increasingly being used to describe the IIMs and to explore the potential link between natalizumab and the onset of IIM in our patient.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"212 1","pages":"197"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73572735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of obesity on rheumatoid arthritis: Relation with disease activity, joint damage, functional impairment and response to therapy 肥胖对类风湿关节炎的影响:与疾病活动性、关节损伤、功能损害和治疗反应的关系

International Journal of Clinical Rheumatology Pub Date : 2018-01-01 DOI: 10.4172/1758-4272.1000209

Gharbia Om, Elkhateeb As, Okasha Ae Abd El-Karim Sa

{"title":"Impact of obesity on rheumatoid arthritis: Relation with disease activity, joint damage, functional impairment and response to therapy","authors":"Gharbia Om, Elkhateeb As, Okasha Ae Abd El-Karim Sa","doi":"10.4172/1758-4272.1000209","DOIUrl":"https://doi.org/10.4172/1758-4272.1000209","url":null,"abstract":"Background and Aim of Work: The impact of Body Mass Index (BMI) on outcomes of Rheumatoid Arthritis (RA) is uncertain. This study aimed to evaluate the influence of obesity on Egyptian patients with RA. Methods: Medical records of 146 RA patients were reviewed. Patients were categorized into normalweight, overweight and obese groups based on BMI. The clinical and laboratory indices of RA activity, the Health Assessment Questionnaire (HAQ) and the radiographic damage score were compared among the groups at baseline, 8, 16 and 24 months. Results: DAS28 and HAQ score were matched at baseline but improved in the 3 groups thereafter, however, differences among the groups become significant only at 24-month. At the 24-month, DAS28 was significantly better in normal-weight (2.1 ± 1.0) and in overweight groups (2.2 ± 0.8) compared to obese group (2.7 ± 1.0) (normal-weight vs obese p=0.003 and overweight vs obese p= 0.006). At the 24-month, HAQ score was significantly better in normal-weight (0.78 ± 0.6) and in overweight groups (0.82 ± 0.5) compared to obese group (1.09 ± 0.7) (normal-weight vs obese p= 0.16 and overweight vs obese p= 0.041). The radiological Sharp-van der Heijde Score along the study period was lower in obese than in overweight or normal-weight patients, albeit the differences in the radiological score were insignificant among the groups. Conclusion: Obese patients were shown to have a poorer response rate to treatment in all outcome measures in comparison to the overweight and the normal-weight RA patients. Future research work is required to investigate whether weight reduction can decrease non-remission rate among the obese RA patients.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"54 1","pages":"346"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84318382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Heterotopic ossification: a challenging complication of total hip arthroplastyrisk factors, diagnosis, prophylaxis and treatment 异位骨化:全髋关节置换术并发症的危险因素、诊断、预防和治疗

International Journal of Clinical Rheumatology Pub Date : 2018-01-01 DOI: 10.4172/1758-4272.1000189

Legosz P, Otworowski M, Sibilska A, Starszak K, Kotrych D, Synder M

{"title":"Heterotopic ossification: a challenging complication of total hip arthroplastyrisk factors, diagnosis, prophylaxis and treatment","authors":"Legosz P, Otworowski M, Sibilska A, Starszak K, Kotrych D, Synder M","doi":"10.4172/1758-4272.1000189","DOIUrl":"https://doi.org/10.4172/1758-4272.1000189","url":null,"abstract":"Background: This review is intended to summaries the risk factors, classification, diagnosis and treatment of heterotopic ossification (HO) of previously published studies. Results: Heterotopic Ossification is a common complication of total hip arthroplasty. Its prevalence isn’t the same in all of the patient groups. Frequency of HO varies from 15% to 90%. Hip ankylosis, male gender and previous history of HO are said to be risk factors with a significant level. Diagnosis is based on a single AP radiograph-the Brooker classification that divides HO into four grades is the most commonly used. The confirmation test that can be used is a bone scan. A great amount of bone metabolic turnover markers have been tested, but none of them seems to be relevant in case of prevention or diagnosis of HO. The most effective prophylactic treatment is radiotherapy or administration of nonsteroidal anti-inflammatory drugs. Over the years a lot of different RT protocols has been tested. Nowadays the most often used regimen is 7 Gy given postoperatively in a single dose. The most commonly prescribed drug in prophylaxis of HO is indomethacin. Also, the efficacy of ibuprofen and diclofenac were proven. Recently researchers focused on selective COX-2 inhibitors. They appear to be as effective as nonselective NSAIDs having less side effects. The one and only treatment of HO is a revision arthroplasty.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"52 1","pages":"218"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81399970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Rheumatic and musculoskeletal manifestations in renal hemodialysis patients 肾性血液透析患者的风湿病和肌肉骨骼表现

International Journal of Clinical Rheumatology Pub Date : 2018-01-01 DOI: 10.4172/1758-42721000196

M. Haroon, S. Sayed, A. Al-ghitany, Haitham Ezzat Tamer A Gheita

{"title":"Rheumatic and musculoskeletal manifestations in renal hemodialysis patients","authors":"M. Haroon, S. Sayed, A. Al-ghitany, Haitham Ezzat Tamer A Gheita","doi":"10.4172/1758-42721000196","DOIUrl":"https://doi.org/10.4172/1758-42721000196","url":null,"abstract":"Objectives: To determine the frequency of Rheumatic and Musculoskeletal Diseases (RMDs) in patients with renal failure on regular hemodialysis. Methods and findings: The present study included forty-nine patients (28 males and 21 females) with renal failure on regular hemodialysis. Full history taking and clinical examination were documented for all patients. Blood samples were collected for laboratory investigations before the mid-week session. Dual Energy X-ray Absorptiometry (DXA) was performed to all patients to assess bone mineral density (BMD). Kt/V was used as a marker of dialysis adequacy. Mean age for all patients was 54.41 ± 15.9 years, and the dialysis duration was 3 ± 2.3 years. The detected RMDs included (in order of descending frequency): fibromyalgia syndrome (51%), myalgias (37%), arthralgia (37%), flexor tenosynovitis (29%), cramps (29%), ectopic calcifications (25%), flexion deformity of the elbow (16%), carpal tunnel syndrome (14%), destructive spondyloarthritis (8%) and Vasculitis (4.1%). Positive anti-CCP was detected in 1 female and rheumatoid factor in 4 females and 1 male. The BMD was reduced with the DXA t-score at lumbosacral spine, hip and forearm -1.5 ± 1.8, -1.7 ± 1.6, -1.9 ± 1.9 respectively. Overall, there was a tendency to a higher frequency of musculoskeletal findings in males. Other co-morbidities included: diabetes mellitus (45%), hypertension (96%), cardiovascular (33%), cerebrovascular stroke (6%), hyperuricemia (37%), hepatitis C (16%) and amyloidosis (8%). Conclusion: Rheumatic and musculoskeletal diseases are frequent and overlooked among hemodialysis patients especially males and usually associated with chronic pain.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"4 1","pages":"263"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82906650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4