发布求助
文献互助 智能选刊 最新文献

Int. J. Comput. Biol. Drug Des.最新文献

筛选
英文 中文
Preface Special Issue: 15th International Symposium on Bioinformatics Research and Applications (ISBRA 2019) 第15届生物信息学研究与应用国际学术研讨会(ISBRA 2019)
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-02-06 DOI: 10.1089/cmb.2019.29024.zc
Zhipeng Cai, P. Skums, A. Zelikovsky
{"title":"Preface Special Issue: 15th International Symposium on Bioinformatics Research and Applications (ISBRA 2019)","authors":"Zhipeng Cai, P. Skums, A. Zelikovsky","doi":"10.1089/cmb.2019.29024.zc","DOIUrl":"https://doi.org/10.1089/cmb.2019.29024.zc","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"32 1","pages":"131-132"},"PeriodicalIF":0.0,"publicationDate":"2020-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77097048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LCLE: a web portal for lncRNA network analysis in liver cancer LCLE:肝癌lncRNA网络分析的门户网站
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/IJCBDD.2020.113855
Xiuquan Wang, Keli Xu, Junqing Wang, Yunyun Zhou
{"title":"LCLE: a web portal for lncRNA network analysis in liver cancer","authors":"Xiuquan Wang, Keli Xu, Junqing Wang, Yunyun Zhou","doi":"10.1504/IJCBDD.2020.113855","DOIUrl":"https://doi.org/10.1504/IJCBDD.2020.113855","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"15 1","pages":"520-528"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78980665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In silico drug target identification and pharmacophore mapping for Leishmania donovani based on metabolic pathways 基于代谢途径的多诺瓦利什曼原虫药物靶点识别和药效团定位
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/ijcbdd.2020.10033060
Nikita Chordia, Deepak Bhayal, Priyesh Hardia
{"title":"In silico drug target identification and pharmacophore mapping for Leishmania donovani based on metabolic pathways","authors":"Nikita Chordia, Deepak Bhayal, Priyesh Hardia","doi":"10.1504/ijcbdd.2020.10033060","DOIUrl":"https://doi.org/10.1504/ijcbdd.2020.10033060","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"129 1","pages":"378-389"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86594798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-silico analysis of PON1, PON2 and PON3 genes role in coronary artery disease PON1、PON2和PON3基因在冠状动脉疾病中的作用的计算机分析
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/ijcbdd.2020.10033059
Sana Ashiq, K. Ashiq
{"title":"In-silico analysis of PON1, PON2 and PON3 genes role in coronary artery disease","authors":"Sana Ashiq, K. Ashiq","doi":"10.1504/ijcbdd.2020.10033059","DOIUrl":"https://doi.org/10.1504/ijcbdd.2020.10033059","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"16 1","pages":"415-423"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85939861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
In silico studies of bioactive phytocompounds with anticancer activity from in vivo and in vitro extracts of Justicia wynaadensis (Nees) T. Anderson 在体内和体外提取具有抗癌活性植物化合物的硅片研究
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/IJCBDD.2020.113836
C. D. Vandana, K. Shanti, P. Karunakar, V. Chandramohan
{"title":"In silico studies of bioactive phytocompounds with anticancer activity from in vivo and in vitro extracts of Justicia wynaadensis (Nees) T. Anderson","authors":"C. D. Vandana, K. Shanti, P. Karunakar, V. Chandramohan","doi":"10.1504/IJCBDD.2020.113836","DOIUrl":"https://doi.org/10.1504/IJCBDD.2020.113836","url":null,"abstract":"The current study is aimed at substantiating the anticancer activity of phytocompounds identified from extracts of in vivo and in vitro propagated Justicia wynaadensis (Nees) T. Anderson using in silico molecular docking and dynamics study. Few phytocompounds with anticancer activity based on literature were selected from GC-MS results of aqueous extract, methanolic extract of callus and in vitro propagated leaf of Justicia wynaadensis respectively. Totally twelve ligands were docked with Thymidylate synthase, where the binding affinity and efficiencies were analysed and compared with the reference drug Capecitabine. The docking result suggested the presence of compounds with anticancer activity. All the twelve ligands showed binding affinity ranging from -5.0 kcal/mol to -8.4 kcal/mol. To investigate the mechanism of action of Campesterol, Stigmasterol and Capecitabine with the target protein, these compounds were subjected to dynamic simulation which revealed that Campesterol was more stable than Stigmasterol and could be a potential lead-like molecule.","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"60 1","pages":"582-601"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89388973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interactions of Leptospiral PI-PLC with the membrane phosphoinositides: an insight of the protein-phospholipid association in the pathogenesis 钩端螺旋体PI-PLC与膜磷脂肌苷的相互作用:在发病机制中的蛋白质-磷脂关联的见解
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/ijcbdd.2020.107315
T. Samaha
{"title":"Interactions of Leptospiral PI-PLC with the membrane phosphoinositides: an insight of the protein-phospholipid association in the pathogenesis","authors":"T. Samaha","doi":"10.1504/ijcbdd.2020.107315","DOIUrl":"https://doi.org/10.1504/ijcbdd.2020.107315","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"49 1","pages":"200-208"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90588258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting re-admission to hospital for diabetes treatment: a machine learning solution 预测再次入院治疗糖尿病:一个机器学习解决方案
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/IJCBDD.2020.113823
S. Srinivasan, Y. Paat, Philmore Halls, Ruth Kalule, Thomas E. Harvey
{"title":"Predicting re-admission to hospital for diabetes treatment: a machine learning solution","authors":"S. Srinivasan, Y. Paat, Philmore Halls, Ruth Kalule, Thomas E. Harvey","doi":"10.1504/IJCBDD.2020.113823","DOIUrl":"https://doi.org/10.1504/IJCBDD.2020.113823","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"13 1","pages":"539-554"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81603066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PgenePapers: a novel database and search tools of reported regulatory pseudogenes PgenePapers:一个新的数据库和已报道的调节假基因的搜索工具
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/IJCBDD.2020.113820
Achal Awasthi, Shenglong Tan, Travis S. Johnson, X. Mo, Kunjie Fan, Yan Zhang
{"title":"PgenePapers: a novel database and search tools of reported regulatory pseudogenes","authors":"Achal Awasthi, Shenglong Tan, Travis S. Johnson, X. Mo, Kunjie Fan, Yan Zhang","doi":"10.1504/IJCBDD.2020.113820","DOIUrl":"https://doi.org/10.1504/IJCBDD.2020.113820","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"37 1","pages":"504-519"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76457231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generating simulated SNP array and sequencing data to assess genomic segmentation algorithms 生成模拟SNP阵列和测序数据，以评估基因组分割算法
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/IJCBDD.2020.113822
M. Zucker, K. Coombes
{"title":"Generating simulated SNP array and sequencing data to assess genomic segmentation algorithms","authors":"M. Zucker, K. Coombes","doi":"10.1504/IJCBDD.2020.113822","DOIUrl":"https://doi.org/10.1504/IJCBDD.2020.113822","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"22 1","pages":"438-453"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76199602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a RNA-Seq based prognostic signature for colon cancer 基于RNA-Seq的结肠癌预后标记的发展
Int. J. Comput. Biol. Drug Des. Pub Date : 2020-01-01 DOI: 10.1504/IJCBDD.2020.113872
Bjarne R. Bartlett, Yong Zhu, Mark Menor, V. Khadka, Jicai Zhang, Jie Zheng, B. Jiang, Youping Deng
{"title":"Development of a RNA-Seq based prognostic signature for colon cancer","authors":"Bjarne R. Bartlett, Yong Zhu, Mark Menor, V. Khadka, Jicai Zhang, Jie Zheng, B. Jiang, Youping Deng","doi":"10.1504/IJCBDD.2020.113872","DOIUrl":"https://doi.org/10.1504/IJCBDD.2020.113872","url":null,"abstract":"","PeriodicalId":13612,"journal":{"name":"Int. J. Comput. Biol. Drug Des.","volume":"95 1","pages":"488-503"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80654683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信