Global Journal of Endocrinological Metabolism最新文献

{"title":"Atypical Presentation of Acute Lymphoid Leukemia as Hypercalcemia and Bilateral Renal Calculi","authors":"Madhu Bj, Chithambaram Ns, G. Harish, V. Sarathi","doi":"10.31031/GJEM.2018.02.000546","DOIUrl":"https://doi.org/10.31031/GJEM.2018.02.000546","url":null,"abstract":"","PeriodicalId":134790,"journal":{"name":"Global Journal of Endocrinological Metabolism","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123408315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Futuristic Medicine and its Applications in the Field of Medical Science","authors":"N. Bhattacharya, Priyodarshi Sengupta","doi":"10.31031/GJEM.2018.02.000545","DOIUrl":"https://doi.org/10.31031/GJEM.2018.02.000545","url":null,"abstract":"During the early twentieth century, the idea of regenerating a new body part/organ to compensate lost and dead tissues would have seemed to be a story taken out from the pages of a science fiction book. There used to be huge sufferings and mortality from diseases like tuberculosis, polio, pneumonia, and malaria just to name a few. Cancer would have been a death penalty. AIDS was an unknown disease until 1983 [1]. Since the last three decades, medical science has made rapid strides and developed sophisticated tools for early diagnosis and detection. Presently, diseases like AIDS, malaria, hepatitis, pneumonia, tuberculosis, leprosy and even certain form of cancers are no longer considered to be fatal and deadly. Polio is now a closed chapter in many developing countries. The age we are currently living in, has become more materialistic and so are the demands and needs for a better healthcare system. This has encouraged many scientific communities globally to undertake and embark on new and futuristic journeys to achieve greater heights in the field of medical science. Massive funding from public and private institutions, emergence of science and scientist as a rewarding career, ever-increasing public awareness, inception of the concept of personalized medicine, competitiveness, quest for knowing the unknown and the willingness coupled with acceptance of the public to invest and pay more for a better health and treatment has helped in the advent of many avenues of modern medicine like Stem cell and Regenerative Medicine, Genomic and Molecular Medicine, Organ and Tissue Engineering and Nanomedicine. Many academics often collectively refer these branches of medicines as “Futuristic Medicine” which encompasses a diverse range of multi-disciplinary fields starting from basic biology to biomedical science, and from physical science to medical science. Classification of Futuristic Medicine","PeriodicalId":134790,"journal":{"name":"Global Journal of Endocrinological Metabolism","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125988383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Efficacy and Safety of Hydroxychloroquine in Patients with Type 2 Diabetes Mellitus","authors":"D. Townsend","doi":"10.31031/gjem.2018.02.000543","DOIUrl":"https://doi.org/10.31031/gjem.2018.02.000543","url":null,"abstract":"Type 2 diabetes is a progressive disease and multiple factors were contributing towards its complication [1]. Only with lifestyle interventions or medication therapy with a single agent, adequate glycemic control may not be possible. American Diabetes Association [2] and other guidelines [3] recommend combination therapy when glycated haemoglobin (HbA1c) goal <7% is not achieved or maintained over a 3 to 6 month period. Hydroxychloroquine inhibits insulin degrading enzyme by changing pH of cellular media and therefore may partially increase intercellular insulin availability. Considering the multifaceted effects of hydroxychloroquine, it could slow down the progression from the pre-diabetes stage to diabetes and can also improve the cardiovascular risk profile in diabetes patients with its favourable actions on blood glucose, lipid profile and antithrombotic properties, making it an attractive add on therapeutic choice for the treatment of T2DM patients. There are few randomised trial as well as few observational study indicate that Hydroxychloroquine (HCQ) 400 mg helps to achieve target glycemic parameter as add on in inadequately control type 2 diabetes patients(T2DM). For example, a 24-week trial in 267 patients demonstrated significant reductions in HbA1c and fasting plasma glucose (FPG) with hydroxychloroquine 400mg as compare to pioglitazone 15mg [4]. The change from baseline in HbA1c at 24 weeks was similar between the 2 treatment groups. Research Article Global Journal of Endocrinological Metabolism C CRIMSON PUBLISHERS Wings to the Research","PeriodicalId":134790,"journal":{"name":"Global Journal of Endocrinological Metabolism","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121237164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resverol (Resveratrol) - Beneficial Effect for Prevention and Treatment of Cardio-Metabolic Syndrome","authors":"Stella Shekerdjiiska","doi":"10.31031/gjem.2018.02.000541","DOIUrl":"https://doi.org/10.31031/gjem.2018.02.000541","url":null,"abstract":"","PeriodicalId":134790,"journal":{"name":"Global Journal of Endocrinological Metabolism","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116887619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary and Alternative Treatment Methods used in Adults with Diabetes in Turkey","authors":"E. Gül, Ümmühan Aktürk","doi":"10.31031/GJEM.2018.02.000539","DOIUrl":"https://doi.org/10.31031/GJEM.2018.02.000539","url":null,"abstract":"Specifically, type 2 diabetes carbohydrate is characterized by chronic hyperglycaemia with impaired fatty and protein metabolism. Type 2 diabetes has become an increasingly public health problem with an estimated prevalence of 285 million people globally (corresponding to 6.4% of the adult population in the world). According to the International Diabetes Federation (IDF) projections, more than 550 million people are expected to receive diabetes until 2030 [1]. The use of complementary and alternative medicine (CAM) is increasing worldwide [2]. CAM encompasses all health systems, modalities, and practices other than those intrinsic to the politically dominant health system of a particular society or culture [3]. Among the most commonly used CAM treatments are nutritional supplements, herbal remedies, mental healing, naturopathy, manipulative body based therapy, energy therapy, massage therapy, hypnosis, music therapy and relaxation techniques [2,4]. Due to inadequate treatment regimens available in the US, 2-3.6 million people use complementary and alternative treatment for diabetes treatment [5]. CAMs are of interest in academic, industrial and economic areas due to their high usage frequency [4]. The use of CAM for the management of chronic diseases is becoming increasingly widespread and its use is influenced by the health belief system, culture and tradition, ethnicity, geography and family history [3]. Diabetic patients, one of the chronic illnesses are often able to take supplementary treatments in addition to medical treatments. In addition, it is stated that the rate of using CAM for diabetic patients is higher than other patient groups [6]. In studies conducted all over the world, CAM use was reported for more than two-thirds of the population [7]. Since 1990s, studies on the prevalence of CAM use among patients with diabetes mellitus are growing and the data showed that CAM is a popular choice for diabetes management [3]. These patients often consult with CAM practitioners or self-manage with CAM the rapies based on their own knowledge [2]. Because diabetes is an individual and multidimensional illness and life-long illness, it is thought that individuals lead other alternative practices besides medical treatment [8]. Cinnamon, garlic preparations, cemenia and multi-vitamins are herbal products commonly used among diabetics and researches continue to have hypoglycaemic effects. Body mind applications such as yoga and tai chi are also used by diabetic patients, but the long-term effects on glycemic control are unsatisfactory [7]. Furthermore, the scientific literature on the efficacy of CAM in the treatment of diabetes is relatively infrequent and diverse. On the spot use of persons with diabetes associated with CAM use, there is a concern that when used as a complementary treatment there is a risk of drug interactions and additional complications [9]. Mini Review","PeriodicalId":134790,"journal":{"name":"Global Journal of Endocrinological Metabolism","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126309255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Education and Supplementation to Overcome Malnutrition in Pregnant Mothers for Improving Offspring Development","authors":"T. Arora, Ayesha Salem-Al Murry","doi":"10.31031/gjem.2018.02.000538","DOIUrl":"https://doi.org/10.31031/gjem.2018.02.000538","url":null,"abstract":"The pre-natal environment as well as the health of women during pregnancy is vital to the survival, health, development, growth and longevity of their offspring. Taking folic acid before and during pregnancy has been shown to help prevent fetal birth defects of the central nervous system, specifically neural tube defects [1]. Developing countries have an extraordinary high level of stunted growth rates in children. Evidence suggests that this is the result of malnutrition during the mother’s pregnancy, as well as in the infant, up to three years after delivery. Stunted growth in children and low birth weight are major public health challenges and these are therefore a national priority in some developing countries. In particular, great efforts have been made to address this problem in several parts of Africa where lipid-based nutrient supplements have been provided to pregnant and lactating women as well as for their offspring in order to promote the healthy development of children.","PeriodicalId":134790,"journal":{"name":"Global Journal of Endocrinological Metabolism","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130119975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Obesity among Adolescents in Ekiti State, Nigeria","authors":"Raimi Th, Oluwayemi Io, Oluwayemi Ma","doi":"10.31031/GJEM.2018.02.000537","DOIUrl":"https://doi.org/10.31031/GJEM.2018.02.000537","url":null,"abstract":"Methods: The index study was a cross-sectional study among secondary school adolescents in Ekiti State. After receiving Government approval and school permission to enter the schools, structured questionnaires were administered to students whose parents gave consent to participate in the study. Measurement of weight, height, waist circumference, blood pressure, and fasting blood glucose were done following standard procedures. Binary logistic regression was employed to determine the predictors of obesity","PeriodicalId":134790,"journal":{"name":"Global Journal of Endocrinological Metabolism","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127183234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}