Indian Journal Of Clinical Practice最新文献

A Review of Diabetic Foot Osteomyelitis: Focus on Diagnosis, Clinical Presentation, Management and Outcomes 糖尿病足骨髓炎综述：聚焦诊断、临床表现、管理和结果

Indian Journal Of Clinical Practice Pub Date : 2024-01-23 DOI: 10.59793/ijcp.v34i3.767

Milind G Ruke, Manish Garg

{"title":"A Review of Diabetic Foot Osteomyelitis: Focus on Diagnosis, Clinical Presentation, Management and Outcomes","authors":"Milind G Ruke, Manish Garg","doi":"10.59793/ijcp.v34i3.767","DOIUrl":"https://doi.org/10.59793/ijcp.v34i3.767","url":null,"abstract":"Diabetic foot osteomyelitis (DFO) affects around 38.5 lakh patients in India. It is diagnosed using clinical and radiologicalapproaches. Polymicrobial etiology, peripheral artery disease (PAD) and peripheral neuropathy are commonly observed. Ahigh degree of clinical vigil is required to avoid underestimation of the extent of damage due to speed and spread of infectionand prevent chances of lower extremity amputation. ‘Time is Tissue’ (time taken to access multidisciplinary care) aptlyrepresents one of the critical factors affecting outcomes, along with anatomical location and presence of gangrenous tissues.Traditionally, DFO treatment is the most complex and controversial aspect of managing diabetic foot infections (DFIs). Thetherapeutic paradigm has evolved from high-level surgical resection of all necrotic and infected bone to the more refined andindividualized surgical interventions along with appropriate antibiotics and topical antimicrobials. It is necessary to have asurgeon available with diabetic foot expertise. The surgical outcome is facilitated with strict off-loading, wound management,agitation (freshening and scrapping of wound edges), biofilm disruption and negative pressure wound therapy (NPWT) toaccelerate healing. Formal protocol-driven treatment can be provided by a multidisciplinary team involving surgical, medicaland podiatric specialties to reduce hospital stay and the need for repeat debridement.This review aims to present a completeoverview of the diagnosis, clinical presentation, management and outcomes of DFO according to scientific recommendationsand our experience, along with few illustrative case reports.","PeriodicalId":134500,"journal":{"name":"Indian Journal Of Clinical Practice","volume":"16 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139603752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scrub Typhus with Acute Bilateral Cerebellar Ataxia: A Rare Presentation 恙虫病伴急性双侧小脑共济失调：一种罕见的表现

Indian Journal Of Clinical Practice Pub Date : 2024-01-16 DOI: 10.59793/ijcp.v34i8.761

Dr MAHESH DAVE, Dr DEEPANSHU, Dr NISHANT MANGLA, Dr ANUJ GOYAL, Dr KANHAIYA LAL SHARMA

引用次数: 0

My Work is for a King 我为国王工作

Indian Journal Of Clinical Practice Pub Date : 2024-01-16 DOI: 10.59793/ijcp.v34i8.757

Dr Sanjay Kalra, Dr Jubbin Jacob, Dr Bharti Kalra

引用次数: 0

Collective Consciousness 集体意识

Indian Journal Of Clinical Practice Pub Date : 2024-01-16 DOI: 10.59793/ijcp.v34i8.765

Ijcp

引用次数: 0

Consensus on Stroke Prevention in Atrial Fibrillation and Utilization of NOACs in the Real-World Setting in India 印度心房颤动脑卒中预防共识及 NOACs 在现实世界中的使用情况

Indian Journal Of Clinical Practice Pub Date : 2024-01-16 DOI: 10.59793/ijcp.v34i8.758

CK Ponde, Head, Shah Dhiren, Khan Aziz, Director, Verma Gaurav, Dave Tarun Consultant, Narayana Murthy, John Satish Head, AD Sharma, DB Pawar

{"title":"Consensus on Stroke Prevention in Atrial Fibrillation and Utilization of NOACs in the Real-World Setting in India","authors":"CK Ponde, Head, Shah Dhiren, Khan Aziz, Director, Verma Gaurav, Dave Tarun Consultant, Narayana Murthy, John Satish Head, AD Sharma, DB Pawar","doi":"10.59793/ijcp.v34i8.758","DOIUrl":"https://doi.org/10.59793/ijcp.v34i8.758","url":null,"abstract":"Atrial fibrillation (AF) is the most frequent cardiac arrhythmia. Prevention of stroke and systemic thromboembolism remainsthe cornerstone of the management of AF. Even today, there are unresolved knowledge gaps in AF pathophysiology, screeningand therapeutic strategies and stroke prevention. The modified DELPHI method was used to develop the best practicerecommendations for the management of AF in a real-world setting with the participation of 500 cardiologists across India.The experts concurred that the decision to initiate antithrombotic treatment in patients with transient AF could be based onthe duration of transient AF, the co-existence of the risk factor for stroke and echocardiographic abnormalities impact thedecision. The decision to initiate anticoagulant therapy in device-detected atrial high-rate episodes (AHRE) can be decidedbased on the duration of AHRE, the burden of AHRE and the individual’s risk of stroke and thromboembolism. The benefitof early anticoagulation should be balanced with the risk of intracerebral hemorrhage (ICH), especially in elderly patientsand in severe strokes. Apixaban is the preferred drug in patients with concomitant ischemic heart disease (IHD), patientswith a history of gastrointestinal (GI) bleeding, patients with underlying malignancy, elderly patients with AF, patients withcomorbid diseases and patients with hepatic disease or renal disease. Apixaban was considered to be an affordable noveloral anticoagulant (NOAC) for Indian patients for primary and secondary stroke prophylaxis in AF patients","PeriodicalId":134500,"journal":{"name":"Indian Journal Of Clinical Practice","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139619246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Evaluation of an Ayurvedic Preparation “Sangfer” for the Treatment of Anemia in Pregnant Women: An Open-labeled Clinical Study 治疗孕妇贫血的阿育吠陀制剂 "Sangfer "的临床评估：一项开放标签临床研究

Indian Journal Of Clinical Practice Pub Date : 2024-01-16 DOI: 10.59793/ijcp.v34i8.760

Dr SUSHMA KR, Dr BG VARUNI

{"title":"Clinical Evaluation of an Ayurvedic Preparation “Sangfer” for the Treatment of Anemia in Pregnant Women: An Open-labeled Clinical Study","authors":"Dr SUSHMA KR, Dr BG VARUNI","doi":"10.59793/ijcp.v34i8.760","DOIUrl":"https://doi.org/10.59793/ijcp.v34i8.760","url":null,"abstract":"Background: Iron deficiency during pregnancy is one of the primary causes of anemia in infants and young children. Ithas a negative impact on maternal and fetal health throughout pregnancy with higher likelihood of adverse maternal andfetal outcomes. Maternal iron supplementation is a critical tool to address the global problem of iron deficiency and preventits negative consequences. Method: An open-label non-comparative prospective clinical trial was carried out to evaluatethe effectiveness of “Sangfer” liquid in 16 pregnant women with anemia. “Sangfer” is a polyherbal Ayurvedic proprietarymedication containing elemental iron and zinc and four medicinal herbs viz. Withania somnifera, Emblica officinalis, Asparagusracemosus and Pueraria tuberosa. The aim of the study was to examine its efficacy and safety in treating anemia in pregnantwomen. The dose administered was 10 mL twice daily after food for 12 weeks (84 days). Patients were evaluated at screening(Visit 1 at Day 0), baseline (Visit 2 at Day 1) and during follow-ups (Visit 3 at Day 28, Visit 4 at Day 56 and Visit 5 atDay 84). Results: There was a significant increase in mean hemoglobin levels from 8.08% at Day 1 to 11.19% at the finalvisit at Day 84. The anemia sign and symptom scores also significantly reduced from Day 1 to different follow-up visits.The mean Physician Global Assessment (PGA) score was found to reduce from 1.0 at Day 1 to 0.0 at the final follow-upvisit. Conclusion: “Sangfer” is highly effective for the treatment of anemia during pregnancy. No adverse effects includingserious adverse effects were observed during the study period.","PeriodicalId":134500,"journal":{"name":"Indian Journal Of Clinical Practice","volume":" 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139620253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative Urinals with Proteinuria Detection: A Potential Screening Tool for Diabetic Kidney Disease 创新型蛋白尿检测尿壶：糖尿病肾病的潜在筛查工具

Indian Journal Of Clinical Practice Pub Date : 2024-01-16 DOI: 10.59793/ijcp.v34i8.763

Dr SOURABH SHARMA, Dr HIMANSHU VERMA, Dr SREE BHUSHAN RAJU

{"title":"Innovative Urinals with Proteinuria Detection: A Potential Screening Tool for Diabetic Kidney Disease","authors":"Dr SOURABH SHARMA, Dr HIMANSHU VERMA, Dr SREE BHUSHAN RAJU","doi":"10.59793/ijcp.v34i8.763","DOIUrl":"https://doi.org/10.59793/ijcp.v34i8.763","url":null,"abstract":"Chronic kidney disease (CKD) poses a considerable health challenge, particularly in populations with high-risk factorssuch as diabetes and hypertension. This article proposes a novel and cost-effective approach to address this concern byintegrating proteinuria detection technology into urinals. We suggest the installation of these innovative ‘smart’ urinals inhomes of individuals with diabetes, offering a convenient and proactive means of monitoring kidney health. Furthermore,the deployment of such ‘smart’ urinals in public places could serve as accessible screening facilities, enabling early detectionof CKD in a broader population. The potential cost-benefit ratio of this approach is highlighted, emphasizing the long-termeconomic benefits associated with early intervention. We argue that the proposed technology has the potential to revolutionizeCKD screening, providing a valuable tool for individuals at risk and contributing to the global effort to mitigate the impactof CKD on public health. Further research and pilot programs are warranted to explore the feasibility and effectiveness ofthis innovative screening strategy","PeriodicalId":134500,"journal":{"name":"Indian Journal Of Clinical Practice","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139618258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Survey to Assess the Efficacy and Tolerability of Natural Appetite Stimulants in Pediatric Patients 评估儿童患者天然食欲刺激剂的疗效和耐受性的调查

Indian Journal Of Clinical Practice Pub Date : 2023-08-10 DOI: 10.59793/ijcp.v34i3.570

Durgaprasad Marathe, Pradyumna Ratnakar

{"title":"A Survey to Assess the Efficacy and Tolerability of Natural Appetite Stimulants in Pediatric Patients","authors":"Durgaprasad Marathe, Pradyumna Ratnakar","doi":"10.59793/ijcp.v34i3.570","DOIUrl":"https://doi.org/10.59793/ijcp.v34i3.570","url":null,"abstract":"Anorexia, a common symptom in children, leads to undernutrition, with over 60 million underweight children in India suffering from frequent illnesses. Lack of adequate diet, proper breastfeeding and sufficient protein contribute to increased incidence of undernutrition. Parents often complain their children don't eat enough, making mealtimes difficult and impeding growth. Appetite stimulants like cyproheptadine are available, but side effects like sedation, fatigue, disorientation, impaired coordination, restlessness, excitation and irritability limit their use especially in the pediatric population. The use of herbal supplements has increased worldwide, with parents seeking guidance from pediatricians and primary care professionals regarding the efficacy and safety of these products. The study was a retrospective study conducted via a questionnaire-based survey among all doctors between April and June 2023 to assess the efficacy and tolerability of natural appetite stimulants in pediatric patients. Results showed that patients in the age group of 0 to 5 years (23.1%) were the most common visitors in the doctor’s clinic and appetite stimulant agents were being prescribed most of the time (44.8%). They preferred prescribing natural appetite stimulant mostly (34.3%) for poor appetite (37.3%), followed by poor weight gain and growth (22.8%). The natural appetizer was found to nonaddictive and nonsedative with an improvement in the overall well-being (31.3%) among patients. The results suggest that the natural intervention has the potential to serve as a valuable adjunctive therapy in managing appetite challenges and promoting healthy weight gain in pediatric populations and to optimize pediatricnutrition and overall well-being. ","PeriodicalId":134500,"journal":{"name":"Indian Journal Of Clinical Practice","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122127793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Laurence-Moon-Bardet-Biedl Syndrome: A Rare Case Report Laurence-Moon-Bardet-Biedl综合征:一例罕见病例报告

Indian Journal Of Clinical Practice Pub Date : 2023-08-10 DOI: 10.59793/ijcp.v34i3.573

Mahesh Dave, Anuj Goyal, Deepanshu, Ram Gopal Saini, Gaurav Dave

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The Pyinsa Rupa Model of Diabetes Care: Inspiration from Myanmar Pyinsa Rupa糖尿病护理模式:来自缅甸的启示

Indian Journal Of Clinical Practice Pub Date : 2023-08-10 DOI: 10.59793/ijcp.v34i3.569

Ko Ko, Moe Wint Aung, Ye Myint, Sudhanshu Sharma, Sanjay Kalra

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