JURNAL FARMANESIA最新文献

PENGGUNAAN EKSTRAK KELOPAK JANTUNG PISANG KEPOK (Musa acuminate L.) DALAM FORMULASI PEWARNA RAMBUT

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2792

Cut Masyitah Thaib, Raissa Fitri, Siti Nurbaya, A. Simatupang

{"title":"PENGGUNAAN EKSTRAK KELOPAK JANTUNG PISANG KEPOK (Musa acuminate L.) DALAM FORMULASI PEWARNA RAMBUT","authors":"Cut Masyitah Thaib, Raissa Fitri, Siti Nurbaya, A. Simatupang","doi":"10.51544/jf.v8i2.2792","DOIUrl":"https://doi.org/10.51544/jf.v8i2.2792","url":null,"abstract":"Hair dye preparations are cosmetics used in hair makeup to color hair, either to restore the original hair color or change the original hair color to a new color. Kepok banana heart contains dyes and produces anthocyanins which are used as a safe food coloring. The purpose of this study was to determine that the leaf extract of the Kepok banana heart can be formulated as a hair dye and to determine the concentration of the banana flower extract that produces the best color. Kepok banana flower petals were extracted by maceration method using 96% ethanol, then concentrated to obtain Kepok banana flower petals extract. Hair dye preparations were made with a formula consisting of Kepok banana flower petals extract with various concentrations, namely: 2.5%, 5%, 7.5% and 10%. Staining is done by soaking for 1-4 hours. Observation of color stability was carried out by means of a stability test against 15 washings and exposure to the sun for 5 hours on colored hair, and a biological test (irritation). This study showed that the formula made with the extract of the petals of the Kepok banana heart can give a black color. The best staining was obtained from formula C, namely the extract of the petals of the banana heart of the Kepok banana with a concentration of 7.5% which produced a dark black color. The stability test for 15 washes and the stability test against the sunlight for 5 hours showed that there was no discoloration and no irritation to the skin. It can be concluded that Kepok banana flower petal extract can be used as hair dye.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116685284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

UJI AKTIVITAS ANTIBAKTERI DARI BLACK GARLIC DENGAN VARIASI WAKTU BERBEDA TERHADAP Streptococcusmutans PENYEBAB KARIES GIGI 对导致蛀牙的链球菌菌的抗菌活性进行了不同时间变化的测试

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2797

V. Purwandari, Jon Kenedy Marpaung, Suharyanisa Suharyanisa

{"title":"UJI AKTIVITAS ANTIBAKTERI DARI BLACK GARLIC DENGAN VARIASI WAKTU BERBEDA TERHADAP Streptococcusmutans PENYEBAB KARIES GIGI","authors":"V. Purwandari, Jon Kenedy Marpaung, Suharyanisa Suharyanisa","doi":"10.51544/jf.v8i2.2797","DOIUrl":"https://doi.org/10.51544/jf.v8i2.2797","url":null,"abstract":"Dental cariesand gingivitis are the two mostcommon dental and oral diseases in human society. The main cause of both diseasesis a collection of bacteria bound in anorganicmatrix and firmlyattachedtothe tooth surface known as plaque. Black garlicis garlic that has been processed by fermentationat a certaintemperaturefor a long time, resulting in new compounds that have pharmacological effects showing broad antibiotic properties against gram-positiveand gram-negative bacteria, includingstrains that are multi-bacterial. Antibiotic resistance. The purpose of this study was to determine the antibacterial activity of black garlic against Streptococcus mutans bacteria and to determine the differences in the variation of the antibacterial fermentation time of blackgarlicon the antibacterial activity of Streptococcus mutans bacteria. The methodused in this study isanexperimentalmethod (experimentalresearch) to determine the effect of blackgarlic as anantibacterial against Streptococcusmutans. The resultsobtained fromthis study are blackgarlic extract containsalkal oids, flavonoids, tannins, andsaponins. Black garlic extract from variations of 7 days, 12 days, 15 days, and Chlorhexidine had an inhibitoryzone with a strong category while steriledistilled water had an inhibitionzone in the weakcategory.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116720831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FORMULASI SEDIAAN PEMBUATAN PELEMBAB BIBIR (LIP BALM) MENGGUNAKAN SARI BUAH PEPAYA(Carica papaya L.)

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2833

Supartiningsih Supartiningsih, S. Maimunah, Elly Sitorus, S. Lestari

{"title":"FORMULASI SEDIAAN PEMBUATAN PELEMBAB BIBIR (LIP BALM) MENGGUNAKAN SARI BUAH PEPAYA(Carica papaya L.)","authors":"Supartiningsih Supartiningsih, S. Maimunah, Elly Sitorus, S. Lestari","doi":"10.51544/jf.v8i2.2833","DOIUrl":"https://doi.org/10.51544/jf.v8i2.2833","url":null,"abstract":"Lip balm adalah sediaan kosmetik perawatan pada bibir yang digunakan untuk melindungi bibir terhadap faktor lingkungan yang merugikan pada keadaan kelembaban udara yang rendah karena suhu yang terlalu dingin, mencegah penguapan air, serta melembabkan bibir agar tidak mudah kering dan pecah- pecah. Tanaman Buah Pepaya (Carica papaya L.) memiliki kandungan antrakuinon, saponin, lignin, glikosida dan tanin. Tujuan penelitian ini adalah untuk memformulasikan dan uji efektifitas sari buah pepaya pada konsentrasi 1%, 5% dan 9% pada sediaan pelembab bibir. Evaluasi sediaan pelembab bibir yaitu uji homogenitas, uji stabilitas, uji oles, uji daya sebar, uji daya lekat. Metode yang dilakukan dalam penelitian ini adalah bersifat eksperimental. Dari hasil penelitian dan pengujian yang telah dilakukan peneliti didapatkan hasil parameter uji daya lekat adalah (Blanko) 1 menit 10 detik, (F1) 1 menit 02 detik, (F2) 57,66 detik, dan (F3) 44,33 detik. Hasil dari pengujian parameter daya sebar memiliki rata-rata 4 cm, 5 cm, 6 cm dan 6 cm. Lip balm yang diformulasi dalam penelitian ini tidak melalui uji iritasi dikarenakan pandemic virus corona yang membuat peneliti tidak bisa menggunakan sukarelawan manusia. Peneliti juga tidak melalui uji kelembapan pada bibir sukarelawan demi menghidari penyebaran virus dan memenuhi protokol kesehatan.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123334367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

KARAKTERISASI DAN SKRINING FITOKIMIA SERTA ANALISIS FLAVONOID DARI BUAH MENGKUDU (Morindacitrifolia L) SECARA KROMATOGRAFI LAPIS TIPIS 植物的特征特征和化学分析以及青金石的黄酮分析

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2793

Panal Sitorus, Suharyanisa Suharyanisa, Devina Chandra, Berton Sitanggang

{"title":"KARAKTERISASI DAN SKRINING FITOKIMIA SERTA ANALISIS FLAVONOID DARI BUAH MENGKUDU (Morindacitrifolia L) SECARA KROMATOGRAFI LAPIS TIPIS","authors":"Panal Sitorus, Suharyanisa Suharyanisa, Devina Chandra, Berton Sitanggang","doi":"10.51544/jf.v8i2.2793","DOIUrl":"https://doi.org/10.51544/jf.v8i2.2793","url":null,"abstract":"Noni fruit (Morindacitrifolia L.) is a medicinal plant that is well known by the people in Indonesia. Noni is efficacious as an immune enhancer, normalizes blood pressure, anti-cancer, analgesic, diabetes mellitus, heart disease, stroke, antimicrobial. To know the characteristics of simplicia and the class of compounds from the noni fruit as well as to analyze the flavonoid compounds contained in the noni fruit using the thin layer chromatography method. The flavonoid compounds were extracted by maceration using ethanol solvent and then the ethanol extract was tested by thin-layer chromatography using 1% HCl mobile phase and spotting with 1 N H2SO4 reagent and methanol pa (1: 1% v/v). Result of simplicia characterization of fruit Noni, obtained 1.32% water content, 38.41 % water soluble extract content, 16.7% ethanol soluble extract content, 6.09% total ash content, and 0.45 acid insoluble ash content. %. Noni fruit simplicia contains chemical compounds of alkaloids, tannins, flavonoids, triterpenoids/steroids, anthraquinones, saponins with phytochemical screening tests. The value of Rf from the analysis of noni fruit flavonoid compounds using the Thin Layer Chromatography method with 3 repetitions is 0.75; 0.68 and 0.62. This indicates the presence of flavonoid compounds in the noni fruit.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114803548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUNMANGKOKAN (Polyscias scutellaria) TERHADAP BAKTERI Propionibacterium acnes 测试柳甘菊乙醇提取物(多毛虫芽孢杆菌)的抗菌活性

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2795

Siti Nurbaya, Dicky Yuswardi Wiratma, Elly Sitorus, Amalia Insani

{"title":"UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUNMANGKOKAN (Polyscias scutellaria) TERHADAP BAKTERI Propionibacterium acnes","authors":"Siti Nurbaya, Dicky Yuswardi Wiratma, Elly Sitorus, Amalia Insani","doi":"10.51544/jf.v8i2.2795","DOIUrl":"https://doi.org/10.51544/jf.v8i2.2795","url":null,"abstract":"Indonesia is a tropical country that has a variety of plants, one of which is the succulent plant (Polyscias Scutellaria). Mangkukan plant contains flavonoid compounds, alkaloids, saponins, polyphenols, fats. This study aimed to determine the antibacterial activity of the ethanol extract of the leaves of the Mangkokan (Polyscias Scutellaria) against Propionibacterium acnes bacteria. The tests were carried out through the stages of collecting materials, preparing simplicia, making an ethanolic extract of Mangkukan leaves, and testing the inhibitory power of basil leaves against Propionibacterium acnes bacteria. The manufacture of ethanolic extract of the leaves of the Mangkokan was carried out by the maceration method using 96% ethanol. Antibacterial activity testing was carried out using the agar diffusion method using disc paper. The results of the study based on the results of phytochemical screening showed that the simplicia and ethanol extract of the Mangkukan leaf contained alkaloids, flavonoids, glycosides, tannins, saponins, steroids/triterpenes. Meanwhile, the results of the antibacterial activity test of the ethanolic extract of the Mangkokan leaf have antibacterial properties against Propionibacterium acnes at extract concentrations of 30% (6.74 mm), .35% (6.84 mm), 40% (7.26 mm), 45% (7.32 mm), 50% (8.68 mm) with medium resistance zone. The positive control used 30 g chloramphenicol disc paper with an inhibition zone diameter of 21.89 and the negative control used 10% DMSO solution which had no inhibition zone. The ethanol extract of basil leaves has antibacterial activity against Propionibacterium acnes bacteria.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124844432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AKTIVITAS PENGHAMBATAN ENZIM PROTEASE 6LU7 VIRUS SARS-COV-2OLEH SENYAWA FLAVONOID DARI TUMBUHAN GENUS ARTOCARPUS SECARA IN SILICO 蛋白酶抑制活性6LU7, sars - cov -2，由硅属ARTOCARPUS植物的类黄酮化合物引起

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2789

Adiansyah Adiansyah, Dumartina Hutauruk, Lastry Derliana Nainggolan

{"title":"AKTIVITAS PENGHAMBATAN ENZIM PROTEASE 6LU7 VIRUS SARS-COV-2OLEH SENYAWA FLAVONOID DARI TUMBUHAN GENUS ARTOCARPUS SECARA IN SILICO","authors":"Adiansyah Adiansyah, Dumartina Hutauruk, Lastry Derliana Nainggolan","doi":"10.51544/jf.v8i2.2789","DOIUrl":"https://doi.org/10.51544/jf.v8i2.2789","url":null,"abstract":"The genus Artocarpus is one of the genera of Moraceae plants, this genus consists of 50 species and 40 species of them are found in Indonesia. Several studies have reported that the flavonoid compounds contained in the genus Artocarpus have cytotoxic, antiproliferative, antimalarial, anti-inflammatory, and antioxidant properties. The purpose of this study was to determine the inhibitory activity of the protease enzyme 6LU7 of the SARS-COV-2 virus by flavonoid compounds from plants of the genus Artocarpus using the in-silico tethering method. The method used in the in-silico tethering process is carried out using the PLANTS program, validated using the Yasara program, and visualized using the Moe2008 program. The protein model of the 6LU7 Protease Enzyme was downloaded via the Protein Data Bank (PDB) with the code 6LU7. The results of this study indicate that the binding of flavonoid compounds from the genus Artocarpus to the expression of 6LU7 gives valid results in silico. The flavonoid compounds of the Artocarpus genus inhibited the 6LU7 enzyme protein with a higher docking value than each of the comparison drugs and produced 7 amino acid residues that were bound to each other. The conclusion of this study can be concluded that flavonoid compounds from the genus Artocarpus inhibit the expression of 6LU7 protein with a docking score close to the docking score of each comparison drug and 7 amino acid residues are bound to each other.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121681865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PENGARUH MINYAK KELAPA MURNI DAN MINYAK INTI SAWIT TERHADAP PERTUMBUHAN RAMBUT PADA KELINCI 纯棕榈油和棕榈油对兔子头发生长的影响

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2794

M. Suryani, Christica Ilsanna Surbakti, Novia Silvana Hadi

引用次数: 0

PEMBUATAN PATI DARI RIMPANG LENGKUAS, TEMULAWAK, TEMUKUNCI SERTA KARAKTERISASINYA 淀粉的制作包括嫩芽、铁杉、钥匙和它的特性

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2791

Pandapotan Nasution, Suharyanisa Suharyanisa, Manahan Situmorang, Nurpita Putri Manihuruk

引用次数: 1

UJI AKTIVITAS ANTIOKSIDAN SEDIAAN GEL YANG MENGANDUNG EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J. R & G. Forst) DENGAN MENGGUNAKAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazyl) 使用DPPH方法(11-di苯-2 picrylhydrazyl)对含有乙醇提取物的置氧性腺活性测试

JURNAL FARMANESIA Pub Date : 2021-12-26 DOI: 10.51544/jf.v8i2.2796

Wahyu Margi Sidoretno, Rosa Devitria, Harni Sepriyani

{"title":"UJI AKTIVITAS ANTIOKSIDAN SEDIAAN GEL YANG MENGANDUNG EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J. R & G. Forst) DENGAN MENGGUNAKAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazyl)","authors":"Wahyu Margi Sidoretno, Rosa Devitria, Harni Sepriyani","doi":"10.51544/jf.v8i2.2796","DOIUrl":"https://doi.org/10.51544/jf.v8i2.2796","url":null,"abstract":"Matoa (Pometia pinnata J.R & J. G. Forster) is one of the plants that can be used for traditional medicine. Based on several studies, it is stated that the ethanolic extract of matoa leaves has good antioxidant activity. This study aims to determine the antioxidant activity of gel preparations from the ethanolic extract of matoa (Pometia pinnata) leaves. Matoa leaf extract (Pometia pinnata) was prepared using maceration method with 96% ethanol as solvent. Then the extract was formulated into a gel with 4 formulations, namely F0 (no matoa leaf extract), FI (with 0.1% matoa leaf ethanol extract), FII (with 0.3% matoa leaf extract), FIII (with ethanol leaf matoa by 0.5%). Furthermore, the antioxidant activity test was carried out on the gel samples using the DPPH method (1,1-diphenyl-2-picrylhydrazyl) spectrophotometrically at a wavelength of 515 nm. The results of the antioxidant activity test showed that the percentage of inhibition of the 96% ethanol extract of matoa leaf (Pometia pinnata) was F0 40.34%, FI 55.187%, FII 61.703%, FIII 27.969%, and the percentage inhibition of vitamin C was 178.947%. So it can be said that the matoa leaf extract gel has antioxidant activity.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126578754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SKRINING FITOKIMIA DAN ANALISIS ALKALOID DARI TUMBUHAN BABAN DOTAN (Ageratum conyzoides L.) DENGAN METODE KROMATOGRAFI LAPIS TIPIS 多坍黄藻(agertum conyzoides L)的植物化学筛选和生物碱分析。色谱法非常薄

JURNAL FARMANESIA Pub Date : 2021-06-26 DOI: 10.51544/jf.v8i1.2786

P. Nasution, Yosy Silalahi, Jon Kennedy Marpaung, Herdison Simatupang

{"title":"SKRINING FITOKIMIA DAN ANALISIS ALKALOID DARI TUMBUHAN BABAN DOTAN (Ageratum conyzoides L.) DENGAN METODE KROMATOGRAFI LAPIS TIPIS","authors":"P. Nasution, Yosy Silalahi, Jon Kennedy Marpaung, Herdison Simatupang","doi":"10.51544/jf.v8i1.2786","DOIUrl":"https://doi.org/10.51544/jf.v8i1.2786","url":null,"abstract":"Medicinal plants are a type of plant that partially or completely and the exudate of the plant is used as medicine, medicinal ingredients, or medicinal ingredients. One of the plants that has been used by the community is Baban dotan (Ageratum conyzoides Linn.) which is one of the superior medicinal plants that has multifunctional properties. This study aims to determine the content of compounds contained in the Babandotan plant (Ageratum conyzodes Linn.) and analysis of the alkaloid content using the Thin Layer Chromatography Method. In the phytochemical screening examination of baban dotan (Ageratum conyzoides Linn.) plants. Examination of the analysis of alkaloids using the Thin Layer Chromatography method resulted in the results of the active substances in the Baban dotan plant in the form of alkaloid content separating or being attracted from the focal point and obtained 2 spots that appeared with a brownish yellow color. The results showed that in the phytochemical screening and alkaloid analysis of the Babandotan plant (Ageratum conyzoides Linn.) using the Thin Layer Chromatography method, there were characteristics that could be used to identify the plant.","PeriodicalId":132191,"journal":{"name":"JURNAL FARMANESIA","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121529914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0