{"title":"Total intravenous anaesthesia in neonatal surgery: a case series using the Eleveld model","authors":"Weng Ken Chan, Sanah Mohtar, S. Teo","doi":"10.35119/myja.v2i1.36","DOIUrl":"https://doi.org/10.35119/myja.v2i1.36","url":null,"abstract":"The practice of total intravenous anaesthesia (TIVA) target-controlled infusion of propofol (TCI-propofol) during neonatal surgery was limited by the lack of an appropriate pharmacokinetic-pharmacodynamic model and safety concerns. This is due to the physiological differences between the adult and neonate populations as well as inter-individual pharmacodynamic variation. Eleveld is the latest propofol pharmacokinetic model commercially available and the only model with the neonatal population in its algorithm design. We present a case series of neonates that underwent neonatal surgery under TIVA TCI-propofol utilising the Eleveld pharmacokinetic model. There was no observable clinically significant hypotension intraoperatively. Careful titration of TCI-propofol was necessary for timely emergence and maintaining haemodynamic stability. All neonates were extubated well postoperatively and recovered uneventfully. These demonstrated good and desirable anaesthetic effects using TCI-propofol without undesirable short-term side effects, especially clinically significant hypotension.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125141456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Hamzah, Nadia Md Nor, M. Maaya, Syarifah Noor Nazihah Sayed Masri, Rufinah Teo, A. Masdar
{"title":"Pre-oxygenation in obese patients: facemask versus facemask with nasal prong","authors":"N. Hamzah, Nadia Md Nor, M. Maaya, Syarifah Noor Nazihah Sayed Masri, Rufinah Teo, A. Masdar","doi":"10.35119/myja.v2i1.42","DOIUrl":"https://doi.org/10.35119/myja.v2i1.42","url":null,"abstract":"Introduction: Anatomical and physiological changes of the respiratory system in obese patients predispose them to rapid oxygen desaturation during apnoea. Adequate pre-oxygenation before anaesthesia induction allows a period of safe apnoea. The efficacy of pre-oxygenation with facemask versus facemask with nasal prong was compared. The time taken for expired end-tidal oxygen (FEO2) to reach 0.8 (T0.8) from commencement of pre-oxygenation (T0), and time to oxygen desaturation to 95% (T95%), following apnea (TA) was studied.\u0000Methods: This prospective, randomised study recruited 36 surgical patients of body mass index (BMI) ≥ 30 kg/m2 requiring general anaesthesia with endotracheal intubation. They were randomised to receive pre-oxygenation with oxygen facemask at 12 L/min, or concurrent pre-oxygenation with facemask at 7 L/min and nasal prong at 5 L/min. Oxygen saturation (SpO2) and FEO2 were recorded at T0, T0.8, and at TA following completion of rocuronium administration. Oxygen was then discontinued, and the patient left apnoeic with no ventilation. Intubation was performed 60 seconds after TA, and the patient left apnoeic with the endotracheal tube exposed to room air. Duration from TA until the patient’s SpO2 reached 95% (T95%) was documented.\u0000Results: Pre-oxygenation with facemask and nasal prong resulted in a shorter T0.8 compared to facemask alone (48.61 s ± 23.3 versus 77.72 s ± 26.15), p = 0.001. There was no difference in T95% between the groups.\u0000Conclusion: Pre-oxygenation with facemask plus nasal prong resulted in a shorter time taken to reach FEO2 0.8, but with comparable time to oxygen desaturation between both groups.\u0000 ","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131271577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ji Kwan Lee, Zubaidah Jamil Osman, S. I. F. Ismail, K. Tan
{"title":"Psychometric examination of the Malay version of the Pain Catastrophising Scale in a Malaysian chronic pain sample","authors":"Ji Kwan Lee, Zubaidah Jamil Osman, S. I. F. Ismail, K. Tan","doi":"10.35119/myja.v2i1.19","DOIUrl":"https://doi.org/10.35119/myja.v2i1.19","url":null,"abstract":"Introduction: The purpose of this study was to examine the psychometric properties of the Malay version of the Pain Catastrophizing Scale (PCS-M).\u0000Methods: The original PCS was translated into Malay using the back-translation method and was administered to 132 outpatients with non-malignant chronic pain.\u0000Results: Confirmatory factor analysis revealed that a 10-item single-factor model had a better fit profile compared to 8 competing models as documented in previous studies. In terms of internal consistency, Cronbach’s α value for the PCS-M was 0.93. In terms of predictive validity, the PCS-M explained 47%, 24%, and 22% of the variance in anxiety, depression, and kinesiophobia, respectively.\u0000Conclusion: Best presented as a unidimensional construct, the 10-item PCS-M demonstrated excellent reliability estimate and initial evidence for predictive validity in a Malaysian chronic pain sample. The 10-item PCS-M is a reliable and valid tool to be used in chronic pain management in the Malaysian context.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"69 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114034673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Leong, Maizatulhikma Md Miskan, Vanitha Sivanaser
{"title":"Wolff-Parkinson-White syndrome: anaesthetic care for meningioma excision","authors":"K. Leong, Maizatulhikma Md Miskan, Vanitha Sivanaser","doi":"10.35119/myja.v1i2.9","DOIUrl":"https://doi.org/10.35119/myja.v1i2.9","url":null,"abstract":"In Wolff-Parkinson-White (WPW) syndrome, the presence of an accessory pathway between the atrium and ventricle predisposes the patient to paroxysmal supraventricular tachyarrhythmias, which may progress to ventricular fibrillation and sudden cardiac death. Several drugs that are used perioperatively may alter the cardiac conduction velocity and refractory period. This fact, interacting with factors such as increased sympathetic tone (e.g., anxiety, pain, or seizure) or haemorrhage, leads to tachycardia, where shortened R-R interval predisposes the heart to re-entrant tachyarrhythmias. We reported and highlighted the perioperative issues while anaesthetising a 15-year-old boy with WPW syndrome for craniotomy and excision of parietal meningioma.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126909801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Ong, Hui Ping Ng, Muhamad Rasydan Abd Ghani, Shee Ven Wong
{"title":"Continuous spinal anaesthesia, an underutilised neuraxial technique in current anaesthesia practice: a timely reminder","authors":"E. Ong, Hui Ping Ng, Muhamad Rasydan Abd Ghani, Shee Ven Wong","doi":"10.35119/myja.v1i2.7","DOIUrl":"https://doi.org/10.35119/myja.v1i2.7","url":null,"abstract":"Continuous spinal anaesthesia (CSA) is a cardio-stable technique used in high-risk patients undergoing surgery. However, this technique appeared to decline over the last decades due concerns of complications that arise from using this technique, such as post-dural puncture headaches and neurological deficits. We report two cases of elderly patients, one at high cardiac risk and one with dementia and multiple comorbidities, under CSA for orthopaedic surgery with no reported complications. CSA is an adequeate anaesthetic technique with a low failure rate and complications. Proper technique should be taken into consideration to increase the success rate for this procedure.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115791834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ki Yang Soo, N. Ramly, Azrina Md Ralib, J. Liew, N. Talib, M. B. Mat Nor
{"title":"Monocyte distribution width in the detection of sepsis and prediction of mortality in critically ill patients","authors":"Ki Yang Soo, N. Ramly, Azrina Md Ralib, J. Liew, N. Talib, M. B. Mat Nor","doi":"10.35119/myja.v1i2.16","DOIUrl":"https://doi.org/10.35119/myja.v1i2.16","url":null,"abstract":"Introduction: Sepsis is the leading cause of intensive care unit (ICU) admission. Delayed recognition of sepsis is associated with increased morbidity and mortality. Monocyte distribution width (MDW) represents the width of a set of monocyte volume values, which increases as infections progress in severity. This study evaluated the diagnostic and prognostic accuracy of MDW and white cell count (WCC) for sepsis and mortality.\u0000Methods: This was a prospective cohort study of 100 patients who were grouped into sepsis and non-sepsis according to the Sepsis-3 definition. MDW and WCC were collected on admission to ICU and for the subsequent 3 days.\u0000Results: On admission, MDW was diagnostic of sepsis with an AUC of 0.86 (95% CI, 0.7–0.94) with a cut-off threshold of 20.97. Serial MDW on days 1 and 2 were also shown to be predictive of sepsis. MDW has a high sensitivity of 92.1% (95% CI, 82.4–97.4%) but a specificity of only 68.8% (95% CI, 50.0– 83.9%). The positive predictive value and negative predictive value of MDW using the new cut-off threshold in this study were found to be 83.6% (95% CI, 73–91.2 %) and 81.5% (95% CI, 61.9–93.7%), respectively.\u0000Conclusions: MDW is an effective screening tool in the detection of sepsis upon admission to the ICU. As part of the differential in some complete blood count analysis machines, MDW provides a cost-effective and widely available test at present. Early detection of sepsis allows initiation of sepsis care bundle and better clinical outcomes.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117193070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Value-based medicine and precision medicine in anaesthesia","authors":"I. I. Shariffuddin, Azrina Md Ralib","doi":"10.35119/myja.v1i2.35","DOIUrl":"https://doi.org/10.35119/myja.v1i2.35","url":null,"abstract":"Evidence-based medicine has become the part and parcel of the practice of medicine nowadays. 1 It integrates patient preference with evidence and clinicians’ experience, leading to the improvement in the length of life. 1 However, concern arises that it does not consider quality of life; hence, the concept of value-based medicine has become increasingly popular. Value-based medicine incorporates patient-perceived values that emphasise quality of life. 2 In addition","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128980856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of video tutorial on compliance of medical officers to sequence of intubation protocol in simulated Covid-19 patients","authors":"M. Awang, R. H. M. Zaini, W. M. Hassan","doi":"10.35119/myja.v1i2.21","DOIUrl":"https://doi.org/10.35119/myja.v1i2.21","url":null,"abstract":"Introduction: The use of full PPE, aerosol box, and video laryngoscope are recommended when performing intubation on a Covid-19 patient. However, this technique may be difficult for medical officers unfamiliar with the intubation protocol sequence, especially for those with less experience in anaesthesia. Video tutorials may play a vital role in improving the technique. This study evaluated the compliance of medical officers in our anaesthesia department to the intubation protocol and the effect on compliance before and after viewing the video tutorial on the protocol.\u0000Methods: A total of 70 medical officers (n = 70) in the Department of Anaesthesia, Hospital Universiti Sains Malaysia, Kelantan participated in this study. The participants performed the intubation protocol sequence on a simulated Covid-19 mannequin. Participants then viewed a video tutorial after their initial attempt and repeated the intubation sequence afterward. The outcomes measured include the proportion of participants compliant with the intubation protocol, the association between years of experience and compliance, and the compliance score before and after the video tutorial.\u0000Results: There was no significant association between years of anaesthesia and compliance score (p = 0.058). A large proportion of the subjects were compliant (n = 57, 81.4%). There was a significant difference between initial and repeatedcompliance score post-video tutorial (p < 0.05).\u0000Conclusion: Years of experience in anaesthesia was not a determining factor for compliance with the intubation protocol sequence on simulated Covid-19 patients. However, the video tutorial played a significant role in improving compliance withthe intubation sequence.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123810034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Platelet-rich plasma injection for symptomatic relief of disability associated with traumatic knee arthritis: a case report","authors":"Mei Leng. Yap, Awisul-Islah Ghazali","doi":"10.35119/myja.v1i2.30","DOIUrl":"https://doi.org/10.35119/myja.v1i2.30","url":null,"abstract":"Multimodality is the mainstay of osteoarthritis (OA) treatment and intra-articular platelet-rich plasma (PRP) injection is gaining acceptance due to its regenerative properties and being minimally invasive. We present a young woman with Kellgren-Lawrence grade 3 post-traumatic OA in the left knee who refused surgery and opted for pain clinic follow-up. Five PRP injections in intervals of 4 to 9 months were administered in the past 2 years in addition to oral analgesia when necessary. Five ml of PRP was prepared via the double-spin open method and injected under ultrasound guidance to the left knee joint. Visual analogue scale (VAS) for pain was recorded at pre-procedure, and at 1-week and 1-month post-procedure. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was recorded at pre-procedure and 1-month post-procedure. PRP injection successfully reduced the VAS from 5 to 3 at both 1-week and 1-month post-procedure, and resulted in a WOMAC reduction of 54% with improvement in all WOMAC subscales at 1-month post-procedure. Our case showed that PRP injection demonstrated a positive effect on pain relief and physical function improvement in traumatic knee OA.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"13 Suppl 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126238346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intan Zarina Fakir Mohamed, Ye Yun Phang, Zubaidah Zulkipeli, Rohanizah Alias, Ruwaida Isa, Z. Zahari
{"title":"Successful emergency separation of premature omphalopagus conjoined twins: an anaesthetic experience","authors":"Intan Zarina Fakir Mohamed, Ye Yun Phang, Zubaidah Zulkipeli, Rohanizah Alias, Ruwaida Isa, Z. Zahari","doi":"10.35119/myja.v1i2.32","DOIUrl":"https://doi.org/10.35119/myja.v1i2.32","url":null,"abstract":"Anaesthesia for early emergency separation of premature conjoined twins is extremely rare as surgery generally done electively between 2 to 4 months of age. However, urgent separation may be needed due to life-threatening complications. We report a case of successful early separation of premature omphalopagus twins at 36 weeks of gestational age with a combined weight of 2.7 kg. To the best of our knowledge, this was the lowest weight yet reported of successful surgical separation in Malaysia. Early separation was indicated as extrauterine twin-to-twin transfusion with unbalanced blood shunting through the porto-systemic anastomoses within the shared liver parenchyma potentially risked impending life-threatening organ failures. Anaesthesia for the separation of premature conjoined twins in the emergency setting requires extensive multidisciplinary discussion and planning. Factors predicting difficult anaesthesia in this case were the twins’ size and age as well as duration of anaesthesia. Two separate anaesthetic teams were required with all team members well versed in the operative workflow. Simultaneous airway management, prevention of hypothermia, and vigilant haemodynamic monitoring are key to successful anaesthesia in premature conjoined twin separation.","PeriodicalId":132070,"journal":{"name":"Malaysian Journal of Anaesthesiology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122493663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}