发布求助
文献互助 智能选刊 最新文献

Heterocycles最新文献

筛选
英文 中文
Evaluation of 1,3-Thiazole Derivatives with Pharmaceutical and Chemical Activity: a Review 1,3-噻唑类衍生物的药学和化学活性评价综述
IF 0.6 4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/rev-23-1003
Jyothi Damodara, Sheetal Tresa Fernandes, Smitha Maria DSouza
{"title":"Evaluation of 1,3-Thiazole Derivatives with Pharmaceutical and Chemical Activity: a Review","authors":"Jyothi Damodara, Sheetal Tresa Fernandes, Smitha Maria DSouza","doi":"10.3987/rev-23-1003","DOIUrl":"https://doi.org/10.3987/rev-23-1003","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70752119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances on Catalytic Approaches towards the Synthesis of Quinoline Derivatives Using Povarov Reaction 用Povarov反应催化合成喹啉衍生物的研究进展
IF 0.6 4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/rev-23-1004
Chandi C. Malakar, K. Kant, Sourav Banerjee, Chandresh K. Patel, S. Kalita, N. Aljaar, Reetu Reetu, Priyadarshini Naik
{"title":"Advances on Catalytic Approaches towards the Synthesis of Quinoline Derivatives Using Povarov Reaction","authors":"Chandi C. Malakar, K. Kant, Sourav Banerjee, Chandresh K. Patel, S. Kalita, N. Aljaar, Reetu Reetu, Priyadarshini Naik","doi":"10.3987/rev-23-1004","DOIUrl":"https://doi.org/10.3987/rev-23-1004","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70752286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chiral Benzimidazolium N-Heterocyclic Carbene Ligands with Hydroxyamide- or Hydroxyalkyl-Functionalized Wingtip for Cu-Catalyzed Asymmetric Allylic Alkylation 手性苯并咪唑n杂环卡宾配体与羟基酰胺或羟基烷基功能化翼尖铜催化的不对称烯丙基烷基化
4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/com-23-14880
Satoshi Sakaguchi, Shota Takayanagi
{"title":"Chiral Benzimidazolium N-Heterocyclic Carbene Ligands with Hydroxyamide- or Hydroxyalkyl-Functionalized Wingtip for Cu-Catalyzed Asymmetric Allylic Alkylation","authors":"Satoshi Sakaguchi, Shota Takayanagi","doi":"10.3987/com-23-14880","DOIUrl":"https://doi.org/10.3987/com-23-14880","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135441411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Convenient Synthesis of 1,2,4-Triazino[2,3-b]indazol-3-amine Derivatives via Tandem Abnormal Staudinger/Aza-Wittig/Isomerization Reaction 串联异常Staudinger/Aza-Wittig/异构化反应制备1,2,4-三氮基[2,3-b]吲哚-3胺衍生物
4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/com-23-14889
Hai Xie, Lei Zhang, Xiu-Ting Qin, Ji Li, Ya-Li Zhang, Jin-Yu Li
{"title":"A Convenient Synthesis of 1,2,4-Triazino[2,3-b]indazol-3-amine Derivatives via Tandem Abnormal Staudinger/Aza-Wittig/Isomerization Reaction","authors":"Hai Xie, Lei Zhang, Xiu-Ting Qin, Ji Li, Ya-Li Zhang, Jin-Yu Li","doi":"10.3987/com-23-14889","DOIUrl":"https://doi.org/10.3987/com-23-14889","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135445254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triazene-Bridged Nitrogen-Rich Heterocyclic Energetic Compounds 4,4'-(Triaz-1-ene-1,3-diyl)bis(1,2,5-oxadiazol-3-amine) - Synthesis, Characterization and Properties 三氮烯桥接富氮杂环含能化合物4,4'-(三氮-1-烯-1,3-二基)双(1,2,5-恶二唑-3-胺)的合成、表征和性质
4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/com-23-14905
Suming Jing, Jin Zhu, Qianxiong Chen, Keyao Li, Zhineng Wang, Yuanyuan Wang, Jiahao Deng
{"title":"Triazene-Bridged Nitrogen-Rich Heterocyclic Energetic Compounds 4,4'-(Triaz-1-ene-1,3-diyl)bis(1,2,5-oxadiazol-3-amine) - Synthesis, Characterization and Properties","authors":"Suming Jing, Jin Zhu, Qianxiong Chen, Keyao Li, Zhineng Wang, Yuanyuan Wang, Jiahao Deng","doi":"10.3987/com-23-14905","DOIUrl":"https://doi.org/10.3987/com-23-14905","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"181 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135508537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simple Brønsted Acid Catalyzed Three-Component Reactions for Efficient Alkylation of Indolizines with Aromatic Aldehydes and Hantzsch Esters 简单Brønsted酸催化的三组分反应与芳香醛和Hantzsch酯的高效烷基化
4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/com-23-14898
Dongdong Guo, Jiang Geng, Jinyi Shi, Jin Wang, Jiaxian Li, Lin Jiao
{"title":"Simple Brønsted Acid Catalyzed Three-Component Reactions for Efficient Alkylation of Indolizines with Aromatic Aldehydes and Hantzsch Esters","authors":"Dongdong Guo, Jiang Geng, Jinyi Shi, Jin Wang, Jiaxian Li, Lin Jiao","doi":"10.3987/com-23-14898","DOIUrl":"https://doi.org/10.3987/com-23-14898","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135508714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of Highly Active TEMPO Derivatives for Electrochemical Analysis 高活性TEMPO衍生物在电化学分析中的应用
4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/com-23-14879
Kazuhiro Watanabe, Katsuhiko Sato, Fumiya Sato, Masayuki Kumano, Haruka Nakano, Kyoko Sugiyama, Tsutomu Fujimura
{"title":"Application of Highly Active TEMPO Derivatives for Electrochemical Analysis","authors":"Kazuhiro Watanabe, Katsuhiko Sato, Fumiya Sato, Masayuki Kumano, Haruka Nakano, Kyoko Sugiyama, Tsutomu Fujimura","doi":"10.3987/com-23-14879","DOIUrl":"https://doi.org/10.3987/com-23-14879","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135784557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Review on Indole[2,3-a]quinolizidine: The Synthetic Approaches to the Development of Bioactive Indolo[2,3-a]quinolizidine Scaffolds 吲哚[2,3- A]喹诺齐啶的研究进展:生物活性吲哚[2,3- A]喹诺齐啶支架的合成途径
4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/rev-23-1008
Shivendra Singh, Yukti Monga, Shivangi Sharma, Ashu Gupta
{"title":"A Review on Indole[2,3-a]quinolizidine: The Synthetic Approaches to the Development of Bioactive Indolo[2,3-a]quinolizidine Scaffolds","authors":"Shivendra Singh, Yukti Monga, Shivangi Sharma, Ashu Gupta","doi":"10.3987/rev-23-1008","DOIUrl":"https://doi.org/10.3987/rev-23-1008","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136004420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Antitumor Activity of Heterocylic Aurone and Its Analogue Indanone Derivatives 杂环金酮及其类似物吲哚酮衍生物的合成及抗肿瘤活性研究
IF 0.6 4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/com-22-14764
H. Akber Aisa, C. Niu, Heng Wu, Ayitila Maimaitijiang, Dan-Jie Tang, Baoxing Xie
{"title":"Synthesis and Antitumor Activity of Heterocylic Aurone and Its Analogue Indanone Derivatives","authors":"H. Akber Aisa, C. Niu, Heng Wu, Ayitila Maimaitijiang, Dan-Jie Tang, Baoxing Xie","doi":"10.3987/com-22-14764","DOIUrl":"https://doi.org/10.3987/com-22-14764","url":null,"abstract":"– Based on non-classical bioisosterism and the rule of alkene insertion, thirty-five heterocyclic aurones and its analogue indanones derivatives were designed and synthesized. They were evaluated for inhibitory activity against HELA, HT-29 and A549 and HepG2 human cancer cell lines. Among them, twenty-five compounds exhibited moderate to excellent antitumor activity. The minimum value of IC 50 was 1.649±0.083 μM (compound B1 ). The SAR showed that aurone with B ring as aromatic heterocycles such as 4-bromothiophene, quinoline, carbazole and indanone derivatives and some or indanone were more potent than others. Besides, the introduction of acetylated glycosides was beneficial to the activity. Compounds A1 , B1 , C5 , C8 , C10 , C11 , C12 and D1 were promising antitumor agents. Among them, compounds molecular docking studies were performed between B1 , C8 and potential targets Aurora B (PBD: 2BFY). On the basis, the chemical and physical properties, as well as ADMET of active compounds were predicted and analyzed. And it showed that most of compounds had good pharmacokinetic profiles and high safety profiles","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70398643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Supramolecular Self-Assembly Based on Symmetric Tetramethyl-Substituted Cucurbit[6]uril and Small Aromatic Amines 基于对称四甲基取代葫芦b[6]和小芳胺的超分子自组装
IF 0.6 4区 化学
Heterocycles Pub Date : 2023-01-01 DOI: 10.3987/com-22-14771
Qianjun Zhang, Lin Zhang, Jun Zheng, Xuan Wang, Z. Tao
{"title":"Supramolecular Self-Assembly Based on Symmetric Tetramethyl-Substituted Cucurbit[6]uril and Small Aromatic Amines","authors":"Qianjun Zhang, Lin Zhang, Jun Zheng, Xuan Wang, Z. Tao","doi":"10.3987/com-22-14771","DOIUrl":"https://doi.org/10.3987/com-22-14771","url":null,"abstract":"","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70398819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信