Current Research Journal of Pharmaceutical and Allied Sciences最新文献

Traditionally used herbal remedies by the indigenous tribes of Meghalaya: A Review 梅加拉亚邦土著部落传统上使用的草药疗法:回顾

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2022-03-31 DOI: 10.54059/2022.5(1)crjpas_210

T. Kalita

引用次数: 0

Comprehensive review on Alzheimer's Disease: Pathophysiology and its Treatment 阿尔茨海默病:病理生理学及其治疗的综合综述

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-12-31 DOI: 10.54059/2021.4(3)crjpas_206

Prativa Sadhu, S. Sen, Catherine Vanlalhriatpuii

引用次数: 1

Effective scientific writing: A skill that can be learned 有效的科学写作:一种可以学习的技能

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-12-31 DOI: 10.54059/2021.4(3)crjpas_207

Iswar Hazarika

引用次数: 0

Network Pharmacology-Based Approach in Drug Discovery 基于网络药理学的药物发现方法

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-09-30 DOI: 10.54059/2021.4(2)crjpas_196

B. Das

引用次数: 0

A brief study of mechanism, animal models, and management for obesity 肥胖的机制、动物模型和管理的简要研究

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-09-30 DOI: 10.54059/2021.4(2)crjpas_192

R. Haque, Monika Dhaka

引用次数: 0

A Review on the Anti-Viral Activity of Houttuynia cordata: A Possible Herb for the Management and Treatment of COVID-19 治疗新型冠状病毒肺炎可能的中药鱼腥草抗病毒活性研究进展

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-09-30 DOI: 10.54059/2021.4(2)crjpas_190

Emdormi Rymbai

{"title":"A Review on the Anti-Viral Activity of Houttuynia cordata: A Possible Herb for the Management and Treatment of COVID-19","authors":"Emdormi Rymbai","doi":"10.54059/2021.4(2)crjpas_190","DOIUrl":"https://doi.org/10.54059/2021.4(2)crjpas_190","url":null,"abstract":"Plants are an important source of natural products and they play a vital role in the field of medicinal chemistry and pharmaceutical science. Traditional medicines have been practiced and used for thousands of years, mostly in Asian countries, where plants are the main sources of medicine. Houttuynia cordata, a herb that belongs to the family Saururaceae, has a wide range of pharmacological activities and is used traditionally in conditions like anisolobis sores, heatstroke, lung carbuncles, malaria, scrotal abscess, tonsillitis, salammoniac poison and has also been widely accepted to possess anti-cancer, anti-oxidant, anti-hypertension, anti-inflammatory, anti-mutagenic, antibacterial, anti-viral and anti-purulent activity. Moreover, it is one of the herbs that was recognized during pandemic outbreaks, such as Severe Acute Respiratory Syndrome Coronavirus (SARS CoV) in China, virulent Newcastle Disease Virus (VNDV) in Java (Indonesia) and Newcastle (England). In this review, we briefly discuss the role of H. cordata as an anti-viral agent and the possibility of developing a dosage form against Coronavirus disease-19 (COVID-19).","PeriodicalId":131469,"journal":{"name":"Current Research Journal of Pharmaceutical and Allied Sciences","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134440549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Larvicidal activity of ethanolic leaf and seed extract of Croton tiglium against Aedes aegypti 巴豆叶和种子乙醇提取物对埃及伊蚊的杀幼虫活性研究

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-09-30 DOI: 10.54059/2021.4(2)crjpas_191

Parbin Iraqui

{"title":"Larvicidal activity of ethanolic leaf and seed extract of Croton tiglium against Aedes aegypti","authors":"Parbin Iraqui","doi":"10.54059/2021.4(2)crjpas_191","DOIUrl":"https://doi.org/10.54059/2021.4(2)crjpas_191","url":null,"abstract":"Aim and objectives: Mosquitoes are the transmitters of serious human diseases that cause millions of deaths every year. The use of synthetic insecticides causes harmful side effects to the environment and human health. So a natural alternative way is needed to solve this problem. Extracts from the various parts of plants like leaves, seeds, barks and roots can be used to control mosquitoes. This study aims to evaluate the larvicidal activity of ethanolic seed and leaf extracts of a traditionally used medicinal plant Croton tiglium, against Aedes aegypti, the vector of dengue fever. Material and methods: In this study, extracts from the dried leaf and seed powder of the Croton tiglium plant were extracted using ethanol in a soxhlet apparatus. Different concentrations were prepared from the extracts. Third instar larvae of Aedes aegypti were collected from the mosquito culture laboratory of the Life Sciences Department of Dibrugarh University. Prepared concentrations of the extracts were tested against the larvae of Aedes aegypti to evaluate the larvicidal activity by calculating percent mortality. Result: The ethanolic leaf and seed extracts of the selected plant were found effective against the larvae of Aedes aegypti. The 250 ppm concentration of both leaf and seed extracts showed the highest mortality of mosquito larva. The seed extract of this plant was found more effective in killing mosquito larva. Conclusion: From the study, it can be concluded that the ethanolic leaf and seed extracts of Croton tiglium possess larvicidal activity against Aedes aegypti. Hence, it could be useful in controlling mosquitoes without any harmful effects. However, further study and investigation will be needed to isolate and characterize bioactive components from this plant with larvicidal activity and the development of drugs for dengue from the components","PeriodicalId":131469,"journal":{"name":"Current Research Journal of Pharmaceutical and Allied Sciences","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115267147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation by Design (FbD) approach to develop pharmaceutically amended Diclofenac Sodium hydrogel as compared to marketed gel 通过设计(FbD)方法开发药物修饰双氯芬酸钠水凝胶，并与上市凝胶进行比较

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-06-30 DOI: 10.54059/2021.4(1)crjpas_185

Anupama V. Sarma, T. Chakraborty, S. S. Rahman, A. Ahmed

{"title":"Formulation by Design (FbD) approach to develop pharmaceutically amended Diclofenac Sodium hydrogel as compared to marketed gel","authors":"Anupama V. Sarma, T. Chakraborty, S. S. Rahman, A. Ahmed","doi":"10.54059/2021.4(1)crjpas_185","DOIUrl":"https://doi.org/10.54059/2021.4(1)crjpas_185","url":null,"abstract":"The aim of the present study was to develop pharmaceutically better performing Diclofenac Sodium hydrogel through FbD approaches as compared to marketed gel. The quality target product profile was set for the critical quality attributes of the gel. The key material variables like Carbopol 934P, propylene glycol and Triethanolamine (TEA) were optimized using design of experiments. A response surface central composite design was used considering viscosity, pH and cumulative percentage permeation of the drug up to 120 min as responses. TEA had a significant effect on the pH at concentrations of 0.3182-3.6818% (w/w). The applicability of the optimized formulations was influenced by both Carbopol 934P (0.6591-2.3409%; w/w) and propylene glycol (PG; 6.591-23.409%; w/w) content due to their ability to alter the formulation viscosity. The optimized formulation, determined mathematically, contained 1.5% (w/w) Carbopol 934P. 2.0% (w/w) TEA and 15% (w/w) PG. The optimized hydrogel and marketed gel were evaluated for viscosity, spreadability, skin irritation, homogeneity and grittiness, texture analysis, in vitro release and ex vivo permeation studies. When these evaluation parameters were compared with a marketed gel in respect of all the evaluating tests, the optimized hydrogel was found to be far better formulation than the marketed one.","PeriodicalId":131469,"journal":{"name":"Current Research Journal of Pharmaceutical and Allied Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129479979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DNA nano-cocoon: A novel concept DNA纳米茧:一个新概念

Current Research Journal of Pharmaceutical and Allied Sciences Pub Date : 2021-06-30 DOI: 10.54059/2021.4(1)crjpas_188

A. Sarma

引用次数: 0