A brief study of mechanism, animal models, and management for obesity

Abstract

Obesity appears as fat accumulation in adipose tissue from high energy intake and insufficient energy consumption. It is accompanied by several factors such as genetics, environmental, fetal nutrition, energy intake and expenditure, and culture. These factors stimulate several other mechanisms that contribute to obesity and obesity-related disorders such as hypertension, diabetes, arthritis, hyperlipidemia, coronary heart disease, etc. In the present article, we have examined the main factors, symptoms, and special problems associated with obesity, mechanisms of obesity, and the relation of important parameters with obesity. We have also depicted the various animal models for obesity research. Lastly, we have described the management of obesity.