UC Merced Undergraduate Research Journal最新文献_第5页

Beyond the Armchair: Defying the Myth of 1950s Fatherhood From Outside of the Household 超越扶手椅:从家庭外挑战1950年代父亲的神话

UC Merced Undergraduate Research Journal Pub Date : 2022-05-05 DOI: 10.5070/m414157332

H. Pacheco

引用次数: 0

My Parents’ Immigration Stories as a Microcosm of American Colonialism 我父母的移民故事是美国殖民主义的一个缩影

UC Merced Undergraduate Research Journal Pub Date : 2022-05-05 DOI: 10.5070/m414157337

Janelle A. Perez

引用次数: 0

The Isolated Youth’s Modern Musical Aesthetic 孤独青年的现代音乐美学

UC Merced Undergraduate Research Journal Pub Date : 2022-05-05 DOI: 10.5070/m414157336

Caitlyn Klemm

引用次数: 0

Graph-based featurization methods for classifying small molecule compounds 小分子化合物分类的基于图的特征化方法

UC Merced Undergraduate Research Journal Pub Date : 2022-05-05 DOI: 10.5070/m414157338

Randy Posada, Mary S. Silva, Marisa W. Torres, Jonathan R. Allen, Jeff Drocco, Sarah Sandholtz, A. Zemla, Ucsf Spoke Investigative teams

{"title":"Graph-based featurization methods for classifying small molecule compounds","authors":"Randy Posada, Mary S. Silva, Marisa W. Torres, Jonathan R. Allen, Jeff Drocco, Sarah Sandholtz, A. Zemla, Ucsf Spoke Investigative teams","doi":"10.5070/m414157338","DOIUrl":"https://doi.org/10.5070/m414157338","url":null,"abstract":"For over a decade, drug-induced liver injury (DILI) has posed significant drawbacks in the synthesis and development of drugs and remains a consequential concern. With finite success within the existing preclinical models, DILI is one of the main causes of drug withdrawal or termination from the market. Particularly, this withdrawal occurs during the late stages of drug development (Kullak-Ublick, 2017). Since DILI is difficult to diagnose and treat, it has become an obstacle in the drug production market that in turn affects clinicians, pharmaceutical companies, and consumers. We propose a method for learning features of DILI-positive drugs based on the graphical relationships and patterns they possess within a network of biological databases. We also train various statistical and machine learning models on these learned features in order to classify the drugs as DILI-positive or negative. Our methods include Random Forest, Neural networks, and logistic regression classification. We utilize labeled DILI-positive and DILI-negative datasets, which were developed by the FDA and the National center for toxicological research, as well as additional literature datasets (Thakkar, 2020) in order to validate our results and assess our featurization and model accuracy.","PeriodicalId":131320,"journal":{"name":"UC Merced Undergraduate Research Journal","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114317916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

I Got My Attitude From My Mom: Behavioral Inheritance 我的态度来自我妈妈:行为遗传

UC Merced Undergraduate Research Journal Pub Date : 2021-12-02 DOI: 10.5070/m413255533

Destini Nguyen

引用次数: 0

An In-Depth Analysis of the Novel SARS-CoV-2 新型SARS-CoV-2深入分析

UC Merced Undergraduate Research Journal Pub Date : 2021-12-02 DOI: 10.5070/m413255539

Joseph Younan

{"title":"An In-Depth Analysis of the Novel SARS-CoV-2","authors":"Joseph Younan","doi":"10.5070/m413255539","DOIUrl":"https://doi.org/10.5070/m413255539","url":null,"abstract":"The COVID-19 outbreak, originating in China and spreading across the globe, has affected the entire world by taking the lives of millions and leaving millions more in hospital beds fighting for their lives. This infectious disease was considered a pandemic by the World Health Organization (WHO) in March of 2020, and since then has created an urgent response from world leaders and health organizations to develop an effective strategy to overcome this deadly disease and put an end to the pandemic. Several techniques have been developed by health organizations and vocalized by world leaders around the world which have all been helpful in the fight against COVID-19, however this article looks to address how living a healthy lifestyle might also be one of the most important techniques that should be implemented and vocalized in order to put an end to this novel virus. Research has shown that continuous physical activity and healthy eating habits have been and continue to be one of the most effective ways in protecting individuals from severe outcomes after infection with SARS-CoV-2. These practices must be adopted by every individual in order to defeat this disease and ultimately put an end to the COVID-19 pandemic.","PeriodicalId":131320,"journal":{"name":"UC Merced Undergraduate Research Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130214308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sexual Education and the LGBT+ Community: The Impact of Information Sources on Sexual Outcomes 性教育与LGBT+群体:信息源对性结局的影响

UC Merced Undergraduate Research Journal Pub Date : 2021-12-02 DOI: 10.5070/m413255540

Raven Burton, Dr. Ross Avilla

引用次数: 0

Negotiations of Power: The Persistence of Indigenous Meanings of Space in Mission-era Alta California 权力的谈判:使命时代上加利福尼亚空间的土著意义的持续

UC Merced Undergraduate Research Journal Pub Date : 2021-12-02 DOI: 10.5070/m413255537

Kiana Hugins

引用次数: 0

Undergraduate Research Journal Volume 13, Issue 2 Staff 本科生研究学报第13卷第2期

UC Merced Undergraduate Research Journal Pub Date : 2021-12-02 DOI: 10.5070/m413255543

Urj Staff

引用次数: 0

AI Technology Ethics in Cognitive Science: A Review of the Literature 认知科学中的人工智能技术伦理:文献综述

UC Merced Undergraduate Research Journal Pub Date : 2021-12-02 DOI: 10.5070/m413255536

Martos Montiel

引用次数: 0