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Basic approaches to quality assurance of biological test systems in GLP-studies glp研究中生物测试系统质量保证的基本方法
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2020-06-01 DOI: 10.29296/2618723x-2020-02-03
Мария Анатольевна Зайцева, Е.Г. Потапенко, Т.В. Кашина, А. Б. Верведа
{"title":"Basic approaches to quality assurance of biological test systems in GLP-studies","authors":"Мария Анатольевна Зайцева, Е.Г. Потапенко, Т.В. Кашина, А. Б. Верведа","doi":"10.29296/2618723x-2020-02-03","DOIUrl":"https://doi.org/10.29296/2618723x-2020-02-03","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126832909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 2: rabbit 临床前研究中血液生化参数的变异性及参考区间的建立。第二部分:兔子
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2020-06-01 DOI: 10.29296/2618723x-2020-02-01
M. Miroshnikov, K. T. Sultanova, M. Kovaleva, M. Makarova
{"title":"Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 2: rabbit","authors":"M. Miroshnikov, K. T. Sultanova, M. Kovaleva, M. Makarova","doi":"10.29296/2618723x-2020-02-01","DOIUrl":"https://doi.org/10.29296/2618723x-2020-02-01","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129648511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Lung bacterial infections. Animal models 肺部细菌感染。动物模型
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2020-06-01 DOI: 10.29296/2618723x-2020-02-06
L. R. Khaibunasova, К. Borovkova, J. V. Salmova
{"title":"Lung bacterial infections. Animal models","authors":"L. R. Khaibunasova, К. Borovkova, J. V. Salmova","doi":"10.29296/2618723x-2020-02-06","DOIUrl":"https://doi.org/10.29296/2618723x-2020-02-06","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114454484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of the most common pathologies of the stomach in laboratory animals in preclinical studies of drugs 在药物临床前研究中最常见的胃病理在实验动物的综述
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2020-06-01 DOI: 10.29296/2618723x-2020-02-02
J. U. Ustenko, Y. Gushchin
{"title":"A review of the most common pathologies of the stomach in laboratory animals in preclinical studies of drugs","authors":"J. U. Ustenko, Y. Gushchin","doi":"10.29296/2618723x-2020-02-02","DOIUrl":"https://doi.org/10.29296/2618723x-2020-02-02","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134281933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian fluctuation in plasma testosterone levels in adult male rats 成年雄性大鼠血浆睾酮水平的昼夜波动
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2020-06-01 DOI: 10.29296/2618723x-2020-02-04
А.А. Матичин, Н.М. Фаустова, Д.Р. Каргопольцева, М. Н. Макарова
{"title":"Circadian fluctuation in plasma testosterone levels in adult male rats","authors":"А.А. Матичин, Н.М. Фаустова, Д.Р. Каргопольцева, М. Н. Макарова","doi":"10.29296/2618723x-2020-02-04","DOIUrl":"https://doi.org/10.29296/2618723x-2020-02-04","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129549009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New in the science and practice of preclinical research 临床前研究的科学和实践的新进展
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2020-06-01 DOI: 10.29296/2618723x-2020-02-07
M. Makarova
{"title":"New in the science and practice of preclinical research","authors":"M. Makarova","doi":"10.29296/2618723x-2020-02-07","DOIUrl":"https://doi.org/10.29296/2618723x-2020-02-07","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127559260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparative morphology of the oral cavity in experimental animals and humans 实验动物和人类口腔的比较形态学
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2020-03-01 DOI: 10.29296/2618723x-2020-01-02
Y. Gushchin, V. V. Kvanchiani
{"title":"Comparative morphology of the oral cavity in experimental animals and humans","authors":"Y. Gushchin, V. V. Kvanchiani","doi":"10.29296/2618723x-2020-01-02","DOIUrl":"https://doi.org/10.29296/2618723x-2020-01-02","url":null,"abstract":"Summary. In pre-clinical studies on laboratory animals the most often studied substances are oral. The data for different types of laboratory animals is very contradictory and ambiguous. However, the differences between them can have a signifi cant effect on the obtained result. Analysis of the literature data revealed the main features of anatomically and histologically similarity of the human’s and laboratory animals’ oral cavity structure. The oral cavity is the initial section of the digestive system, where the food lump undergoes and chemical treatment. Development of the face and on principle of common embryonic rudiments. Anatomically and histologically the oral cavity of the examined species structures. the structure the oral the nature of the familiar food. First of all the most differences can be in the structure the teeth and the dental formula. So, for example, in humans and rabbits, there are two consecutive generations of teeth, while the remaining animals have only one set. In humans, rodents and hares different and the structure of molars. A cardinal difference was found in the histological structure of the oral mucosa. In humans and partly in rabbits the lining represented by neorogovevayuschy multilayered epithelium, whereas in rodents it keratinized in all departments, also varies the thickness and number of layers. by a multilayered non keratinized epithelium. While in rodents it is keratinizing in all departments and the thickness and number of layers The blood supply, lymph drainage and innervation of the oral cavity occur in the same way in humans and animals. This comparative review will help in the planning of studies and further work with the obtained data, and will also be useful for histologists, physiologists and pathologists working with laboratory animals..","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125295783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Technique of dissection and extracting organs of laboratory animals. Message 6 – minipigs 实验动物解剖摘取器官技术。讯息6 -迷你猪
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2019-12-01 DOI: 10.29296/2618723x-2018-02-08
K. Koptyaeva, A. Muzhikyan, Ya. Guschin, E. Belyaeva, M. Makarova, V. Makarov
{"title":"Technique of dissection and extracting organs of laboratory animals. Message 6 – minipigs","authors":"K. Koptyaeva, A. Muzhikyan, Ya. Guschin, E. Belyaeva, M. Makarova, V. Makarov","doi":"10.29296/2618723x-2018-02-08","DOIUrl":"https://doi.org/10.29296/2618723x-2018-02-08","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128298584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Primates as a model for research 灵长类动物作为研究的模型
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2019-12-01 DOI: 10.29296/2618723x-2019-04-10
D. D. Karal-Оgly
{"title":"Primates as a model for research","authors":"D. D. Karal-Оgly","doi":"10.29296/2618723x-2019-04-10","DOIUrl":"https://doi.org/10.29296/2618723x-2019-04-10","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114867120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Approbation of the cisplatin-induced acute vomiting model in ferret and choice of reference treatment 顺铂致雪貂急性呕吐模型的建立及参考治疗方法的选择
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science) Pub Date : 2019-09-01 DOI: 10.29296/2618723x-2019-03-10
A. Katelnikova, A. A. Zueva, A. Matichin, D. R. Kargopolceva, D. Gajdaj
{"title":"Approbation of the cisplatin-induced acute vomiting model in ferret and choice of reference treatment","authors":"A. Katelnikova, A. A. Zueva, A. Matichin, D. R. Kargopolceva, D. Gajdaj","doi":"10.29296/2618723x-2019-03-10","DOIUrl":"https://doi.org/10.29296/2618723x-2019-03-10","url":null,"abstract":"","PeriodicalId":131225,"journal":{"name":"Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129810579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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