American Research Journal of Dermatology最新文献

{"title":"Cosmetics’ Safety: Gray Areas with Darker Inside","authors":"Abdul Kader Mohiuddin","doi":"10.21694/2642-2980.19006","DOIUrl":"https://doi.org/10.21694/2642-2980.19006","url":null,"abstract":"Cosmetic items contain a wide scope of chemicals to which we are exposed every day. All cosmetics were separated into 3 classifications: rinse-off items (shower gel, shampoo, toothpaste, liquid soap, private soap, shaving foam) leave-on items (body cream, face cream, hand cream, antiperspirant, sunscreen, post-shaving astringent) and make-up ones (lipstick, lip-balm, foundation, nail polish).The utilization of a significant number of these substances is permitted inside specific limits, because of their toxicity at higher concentrations. Other significant viewpoints ought to be considered as, for example, the likelihood of long-term effects. In the light of the continuous and close nature of the contact on skin and mucosa with these items, it is significant that they don't contain conceivably perilous substances. Additionally, the everyday use and continuous exposition of people to a wide scope of personal consideration items and to various types of chemicals, got from a few sources, may cause the alleged \"cocktail effect\" because of the synergistic interaction of various substances and, likewise, the \"added substance effect\" in light of the nearness of a similar ingredient in numerous items. Actually, every one of the ingredients utilized in cosmetic items meet certain regulatory prerequisites. Notwithstanding, the utilization of numerous substances is permitted inside specific limits, because of their toxicity at higher concentrations.","PeriodicalId":131070,"journal":{"name":"American Research Journal of Dermatology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134421951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urbanization, Environmental Pollution & Skin Aging","authors":"","doi":"10.21694/2642-2980.19007","DOIUrl":"https://doi.org/10.21694/2642-2980.19007","url":null,"abstract":"","PeriodicalId":131070,"journal":{"name":"American Research Journal of Dermatology","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124417269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antifungal activity of selenium nanoparticles and selenium disulfide against two Malassezia species","authors":"Faranak Mavandadnejad, Elnaz Faghfuri, Narges Mokhtari-Nori, S. Rezaie, A. Shahverdi","doi":"10.21694/2642-2980.19002","DOIUrl":"https://doi.org/10.21694/2642-2980.19002","url":null,"abstract":"Yeasts of the genus Malassezia are lipophilic fungi of the normal skin flora of humans and other warm-blooded animals, but they may also be the cause of skin disorders, including dandruff and seborrhoeic dermatitis [Aggarwal ,et al.,2003; Anwar et al.,2016; Roques ,et al.,2006; Rudramurthy et al.,2014]. Seborrhoeic dermatitis (SD), covering areas of the scalp, face and trunk, is a superficial inflammatory skin disorder, which affects 1%10% of the population[Roques et al., 2006]. These diseases are treated with antimycotic shampoos containing various antifungal agents, including selenium disulfide (SeS2), which has antifungal activity against a variety of fungi, including Malasseziaspp[Aggarwal ,et al., 2003; Chu et al., 1984; McGinley et al., 1982; Van Cutsem et al.,1990]. A low concentration of selenium is essential to living organisms [Kitajima et al., 2013]. As a trace element, it is incorporated in the amino acids of selenoproteins and antioxidant enzymes and it protects cells from free radicals. However, in higher concentration, it inhibits fungal growth[Keiliszek et al., 2015; Kitajima et al., 2013] The reason for the antifungal activity of selenium inMalassezia has not been studied but Wu et al [Wu et al., 2014] found that a high concentration of selenium damages the cellular oxygen-eliminating system ofPenicilliumexpansum, which leads to an increase in the production of intracellular ROS. In P. expansum, the inhibitory effect is related to the selenium concentration used[Wu et al.,2014]. SeS2 has been shown to have antifungal activity against Malassezia[Aggarwal ,et al., 2003,McGinley et al., 1982]. However, after treatment with antifungal agents, including SeS2, SD tends to relapse. Aggarwal et al treated 20 SD patients once a week for three weeks with 2.5% SeS2 shampoo and one month after therapy found that three of the patients had mild or considerable residual disease. There is a need for finding more effective compounds for the treatment of S.D. and investigating the reason for the recurrence of infection after SeS2 treatment. Antifungal Activity of Selenium Nanoparticles and Selenium Disulfide against Two Malassezia Species Research Article Open Access American Research Journal of Dermatology Volume 1, Issuse 1, pp: 22-28","PeriodicalId":131070,"journal":{"name":"American Research Journal of Dermatology","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127379129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudo-Tumoral Cutaneous Leishmaniasis","authors":"","doi":"10.21694/2642-2980.19009","DOIUrl":"https://doi.org/10.21694/2642-2980.19009","url":null,"abstract":"A 53-year-old man from a rural area in Tunisia presented with a 2 month history of asymptomatic and persistent vegetating lesion on the dorsal aspect of the right ankle (Figure 1). Physical examination showed a 15 x 6 cm vegetating and pseudo-tumoral lesion with a papillomatous aspect and large ulceration on surface, a soft moist consistency and an indurated base (Figure 2). The rest of the examination was unremarkable. Optical examination of the smears (taken from two sites), after May–Grünwald–Giemsa staining, revealed amastigote forms of the leishmania parasite. Polymerase-chain-reaction (PCR) assay identified Leishmania Major (L. major). The diagnosis of pseudo-tumoral cutaneous leishmaniasis (CL) was confirmed. The patient was treated with meglumine antimoniate intramuscular (60 mg/kg/day) during three weeks. There was a modest and partial response to treatment. Short Communication Open Access American Research Journal of Dermatology ISSN: 2642-2980 Volume 1, Issue 1, pp: 1-3","PeriodicalId":131070,"journal":{"name":"American Research Journal of Dermatology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115851214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heavy Metals: The Notorious Daredevils of Daily Personal Care Products","authors":"Abdul Kader Mohiuddin","doi":"10.21694/2642-2980.19008","DOIUrl":"https://doi.org/10.21694/2642-2980.19008","url":null,"abstract":": Personal care products and facial cosmetics are commonly used by millions of consumers on a daily basis. Direct application of cosmetics on human skin makes it vulnerable to a wide variety of ingredients. Despite the protecting role of skin against exogenous contaminants, some of the ingredients in cosmetic products are able to penetrate the skin and to produce systemic exposure. Consumers’ knowledge of the potential risks of the frequent application of cosmetic products should be improved. While regulations exist in most of the high-income countries, in low income countries there is a lack of similar standards. In most countries for which these legal regulations have been identified, restrictions on the permissible level of heavy metals are strict. There is a need for enforcement of existing rules, and rigorous assessment of the effectiveness of these regulations. The occurrence of metals in cosmetic products is of concern for three principal reasons: (i) the use of cosmetic products could represent a possible source of population-wide exposure daily, and often long-term exposure to metals in cosmetic products (ii) metals can accumulate in the body over time, and (iii) a number of them are known to exhibit different chronic health effects, such as cancer, contact dermatitis, developmental, neurological and reproductive disorders, brittle hair and hair loss. Some metals are potent endocrine disruptors and respiratory toxins. Moreover, some metals, such as Cd, As, Pb, Hg and Sb, are exceptionally toxic with a wide variety of chronic health effects, whereas Cr, Ni and Co are well known skin sensitizers. Since the issue of heavy metals as deliberate cosmetic ingredients has been addressed, attention is turned to the presence of these substances as impurities.","PeriodicalId":131070,"journal":{"name":"American Research Journal of Dermatology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125965216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological Activity of an Essential Oil Blend in Human Dermal Fibroblasts","authors":"Xuesheng Han, Tyler Bahr","doi":"10.21694/2642-2980.19001","DOIUrl":"https://doi.org/10.21694/2642-2980.19001","url":null,"abstract":"Essential oils are complex mixtures of aromatic compounds naturally produced in plants. They have been used historically as well as currently for treating a variety of diseases and maintaining health in humans (Lv et al., 2013; Perry & Perry, 2006). Recent pre-clinical and clinical studies have provided evidence supporting the benefits of essential oils to human health (Kozioł et al., 2014; Navarra et al., 2015), resulting in a wider acceptance and use of essential oils in the US and worldwide. Despite this trend, very few studies have elucidated the mechanisms of action of essential oils inhuman cells.","PeriodicalId":131070,"journal":{"name":"American Research Journal of Dermatology","volume":"31 9‐10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133042063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Regulating Acute Radiodermatitis - A Prospective Study","authors":"","doi":"10.21694/2642-2980.19005","DOIUrl":"https://doi.org/10.21694/2642-2980.19005","url":null,"abstract":"","PeriodicalId":131070,"journal":{"name":"American Research Journal of Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129539330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}